• Journal of Applied Biological Chemistry
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• v.49 no.4
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• pp.143-147
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• 2006

A rapid PCR-based assay for detecting hepatitis B viral DNA(HBV DNA) in serum and plasma was developed using a new PCR instrument named GenSpector(TMC-1000, Samsung electronics). PCR was carried out using a chip-based platform, which enabled 50 PCR cycles with internal controls, and melting-curve analysis in 30 minutes. Verification of the amplified HBV DNA product and the internal control was based on specific melting temperatures(Tm) analysis, executed by the GenSpector software. Primers were designed within the region conserved through HBV genotypes A to F. The lower limit of detection was 840 copies/ml serum, conducted with serial dilutions of a HBV DNA positive control(ACCURUN 325 series 700, Boston Biomedica Inc.). The assay was also compared to another assay for HBV DNA(Versant HBV DNA 3.0 assay, Bayer HealthCare) for 200 samples(each 100 clinical negative and positive samples). The sensitivity and specificity were 100% matched. This rapid PCR-based assay is specific, reproducible, and enables qualitative detection of HBV DNA.

• Journal of Multimedia Information System
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• v.5 no.1
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• pp.27-34
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• 2018

In recent years, with the blooming of Internet of Things (IoT) and Cloud Computing (CC), researchers have begun to discover new methods of technological support in all areas (e.g. health, transport, education, etc.). In this paper, in order to achieve a type of network that will provide more intelligent media-data transfer new technologies were studied. Additionally, we have been studied the use of various open source tools, such as CC analyzers and simulators. These tools are useful for studying the collection, the storage, the management, the processing, and the analysis of large volumes of data. The simulation platform which have been used for our research is CloudSim, which runs on Eclipse software. Thus, after measuring the network performance with CloudSim, we also use the Cooja emulator of the Contiki OS, with the aim to confirm and access more metrics and options. More specifically, we have implemented a network topology from a small section of the script of CloudSim with Cooja, so that we can test a single network segment. The results of our experimental procedure show that there are not duplicated packets received during the procedure. This research could be a start point for better and more efficient media data transmission.

• Smart Structures and Systems
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• v.26 no.1
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• pp.11-21
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• 2020

The hinge joint is the key to the overall cooperative working performance of the assembled beam bridge, and it is also the weakest part during the service period. This paper proposes a method for monitoring and evaluating the lateral cooperative working performance of fabricated beam bridges based on dynamic strain correlation coefficient indicator. This method is suitable for monitoring and evaluation of hinge joints status between prefabricated girders and overall cooperative working performance of bridge, without interruption of traffic and easy implementation. The remote cloud monitoring and diagnosis system was designed and implemented on a real assembled beam bridge. The algorithms of data preprocessing, online indicator extraction and status diagnosis were given, and the corresponding software platform and scientific computing environment for cloud operation were developed. Through the analysis of real bridge monitoring data, the effectiveness and accuracy of the method are proved and it can be used in the health monitoring system of such bridges.

• The Journal of Korean Physical Therapy
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• v.21 no.3
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• pp.75-80
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• 2009

Purpose: The purpose of this study was to examine the effect of an obstacle height on the balance control of older adults while stepping over an obstacle from a position of quiet stance. Methods: Fifteen community-dwelling healthy older adults (mean age, $74.4\pm4.27$ yrs; age range, 67-82 yrs) volunteered to participate in this study. The subjects performed gait initiation (GI) and they stepped over obstacles of two different heights (10 cm and 18 cm) at a self-paced speed from a position of quiet stance. Their performance was assessed by recording the changes in the displacement of the COP in the anteroposterior (A-P) and mediolateral (M-L) directions using a force platform. Results: The M-L displacement of the COP significantly increased for an 18 cm obstacle height condition as compared to the GI and a 10 cm obstacle height condition (p<0.01). Furthermore, the M-L displacement of the COP for a 10 cm high obstacle was significantly greater for that for the GI (p<0.01). However, the mean of the A-P displacement of the COP was similar between the stepping conditions for the A-P displacement of the COP (p>0.05). Conclusion: This study suggests that the M-L COP displacement could be a better parameter to identify the dynamic balance control in older adults when negotiating obstacles.

• Korean Journal of Applied Biomechanics
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• v.21 no.1
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• pp.9-16
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• 2011

The purpose of this study is to analyze the effects of both various shoe types and bare feet on ground reaction force while walking. Ten first-year female university students were selected. A force platform(Kistler, Germany) was used to measure ground reaction force. Six types of shoe were tested: flip flops, canvas shoes, running shoes, elevated forefoot walking shoes, elevated midfoot walking shoes, and five-toed shoes. The control group was barefooted. Only vertical passive/active ground reaction force variables were analyzed. The statistical analysis was carried out using the SAS 9.1.2 package, specifically ANOVA, and Tukey for the post hoc. The five-toed shoe had the highest maximum passive force value; while the running shoe had the lowest. The first active loading rate for running shoes was the highest; meanwhile, bare feet, the five-toed shoe, and the elevated fore foot walking shoe was the lowest. Although barefoot movement or movement in five toed shoes increases impact, it also allows for full movement of the foot. This in turn allows the foot arch to work properly, fully flexing along three arches(transverse, lateral, medial), facilitating braking force and initiating forward movement as the tendons, ligaments, and muscles of the arch flex back into shape. In contrast movement in padded shoes have a tendency to pound their feet into the ground. This pounding action can result in greater foot instability, which would account for the higher loading rates for the first active peak for padded shoes.

• Journal of Nutrition and Health
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• v.19 no.5
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• pp.333-341
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• 1986

Several aspects including physical development, reflex acquistion, neuromotor development and learning behavior at Y water maze were compared at the progeny of rats fed low 91.2mg/kg diet) or adequate leves(22mg/kg diet 0 of pyridoxine during growth, gestation, lactation, and adult period. Physical development and development of reflexes (righting reflex, cliff avoidance, negative geotaxis, palmar grasp, and startle reflex to sound) appeared different between control and deficient groups but not significantly. At the 2nd week, rats spent more time in supported standing during 6 minute period was longer in the control then the deficient groups. In the Y-water maze position reversal test, learning ability as judged by the number of errors was not different among three groups, but the rats in supplemented group(DC) reached the escape platform in significantly shorter time than the other two groups, which may suggest their emotional instability. In the visual discrimination test, the performance of rats from the supplemented group had the lower errors than the other groups on the early test days. but as the testing period progressed, the performance of rats in the supplemented group became inferior to those of the control and deficient groups. The performance of control group became superior to that of the deficient group.

• BMB Reports
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• v.49 no.5
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• pp.263-269
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• 2016

The intestine represents the largest and most elaborate immune system organ, in which dynamic and reciprocal interplay among numerous immune and epithelial cells, commensal microbiota, and external antigens contributes to establishing both homeostatic and pathologic conditions. The mechanisms that sustain gut homeostasis are pivotal in maintaining gut health in the harsh environment of the gut lumen. Intestinal epithelial cells are critical players in creating the mucosal platform for interplay between host immune cells and luminal stress inducers. Thus, knowledge of the epithelial interface between immune cells and the luminal environment is a prerequisite for a better understanding of gut homeostasis and pathophysiologies such as inflammation. In this review, we explore the importance of the epithelium in limiting or promoting gut inflammation (e.g., inflammatory bowel disease). We also introduce recent findings on how small RNAs such as microRNAs orchestrate pathophysiologic gene regulation.

• The Journal of Korean Physical Therapy
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• v.21 no.4
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• pp.51-56
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• 2009

Purpose: This study examined the difference in the static balance ability according to the visual cues and postural tasks in normal subjects. Methods: Thirty participants (12 male, 18 female; mean age $24.63\pm1.43$ years) stood barefoot on a force platform in a one-legged stance, tandem Romberg stance and tandem Romberg with neck extension stance with a visual cue open and closes. The static balance was assessed by the center of pressure (CoP), surface electromyography root mean square (RMS) of the leg muscles according to the stance position. Results: In the CoP tests, the difference in the unit path length and circumference area was affected by the visual cue according to the stance posture (p<0.01). In the RMS tests, the difference in the tibialis anterior and medial gastrocnemius muscle was affected by visual cue in accordance with the stance posture (p<0.01). Conclusion: The visual cue and postural task affect the balance ability in normal subjects. Therefore, this study provides clinical evidence that the balance and postural control can be improved. Therapeutic intervention, such as an obstacle course, and a lower leg muscle performance program with a change in the base of support can affect the balance and postural control.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.2
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• pp.529-546
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• 2012

To address the need for autonomous control of remote and distributed mobile systems, Machine-to-Machine (M2M) communications are rapidly gaining attention from both academia and industry. M2M communications have recently been deployed in smart grid, home networking, health care, and vehicular networking environments. This paper focuses on M2M communications in the vehicular networking context and investigates areas where M2M principles can improve vehicular networking. Since connected vehicles are essentially a network of machines that are communicating, preferably autonomously, vehicular networks can benefit a lot from M2M communications support. The M2M paradigm enhances vehicular networking by supporting large-scale deployment of devices, cross-platform networking, autonomous monitoring and control, visualization of the system and measurements, and security. We also present some of the challenges that still need to be addressed to fully enable M2M support in the vehicular networking environment. Of these, component standardization and data security management are considered to be the most significant challenges.

• Journal of radiological science and technology
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• v.23 no.1
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• pp.103-111
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• 2000

In recent years, medical procedures have become more complex, while financial pressures for shortened hospital stays and increased efficiency in patient care have increased. As a result, several shortcomings of present film-based systems for managing medical images have become apparent. Maintaining film space is labor intensive and consumes valuable space. Because only single copies of radiological examinations exist, they are prone to being lost or misplaced, thereby consuming additional valuable time and expense. In this paper, MINI-PACS for image archiving, transmission, and viewing offers a solution to these problems. Proposed MINI-PACS consists of mainly four parts such as Web Module, Client-Server Module, Internal Module, Acquisition Module. In addition, MINI-PACS system includes DICOM Converter that Non-DICOM file format converts standard file format. In Client-Server Module case, Proposed system is combined both SCU(Service Class User: Client) part and SCP(Service Class Provider: Server)part therefore this system provides the high resolution image processing techniques based on windows platform. Because general PACS system is too expensive for Medium and Small hospitals to install and operate the full-PACS. Also, we constructed Web Module for database connection through the WWW.