• Clinical Nutrition Research
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• 제12권4호
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• pp.293-303
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• 2023

Patients with chronic renal failure, many of which treated with hemodialysis, present a high prevalence of impaired muscle strength which suggest that muscle mass parameters may be used as markers for changes in muscle in these patients. Measurement of handgrip strength (HGS) is a common, simple, and quick measure of muscle function an indicator of overall muscle strength which has been associated with physical activity and several anthropometric traits. Intercellular adhesion molecule-1 (ICAM-1) and insulin-like growth factor-1 (IGF-1) are biochemical markers associated with inflammatory processes which are a common consequence of dialysis. Additionally, hemodialysis patients frequently present signs of malnutrition and depression. This cross-sectional study aimed to evaluate if muscle and biochemical markers could be used to predict the risk of depression in hemodialysis patients. Several anthropometric parameters, nutrient intake, depression state and the serum levels of ICAM-1 and IGF-1 were determined and Pearson's correlation coefficient and/or Spearman's correlation coefficient were used to test the correlation between them. Our results do not show a correlation between HGF, IGF-1 and ICAM-1 with the depression status of the patients, but mid-arm muscle circumference (MAMC) was statistically and positively correlated with depression. Additionally, ICAM-1 levels were negatively correlated with HGS, MAMC, and IGF-1. Overall, the results of the present study suggest that HGS may be used as an indicator of cardiovascular diseases and MAMC may be a good predictor of the level of depression in hemodialysis patients, although further studies are required.

• Journal of Nutrition and Health
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• 제31권7호
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• pp.1130-1138
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• 1998

The objective of this study was to investigate the relationship between changes in body temperature, adiposity and sympathoadrenal activity in normal weight female college students, eating an instant-noodle lunch in a laboratory setting at ambient temperatures of 22-24.8$^{\circ}C$. Preprandial epinephrine(EPI) concentration, as an indicator of adrenal activity, was inversely and significantly correlated with body weight, body mass index(BMI), and waist girth. Changes in pre- and postprandial EPI concentrations showed positive correlations with % body fat, fat mass, waist girth, hip girth, and waist/hip girth ratio(WHR). The preprandial norepinephrine (NE) concentration was negatively correlated with recovery time from the peak postprandial core temperature to the meal-start core temperature(RTST). However, the NE concentration, an indicator of sympathetic neural activity, was not related to anthropometric measurements in normal weight young women. In conclusion, adrenal activity was negatively associated with adiposity and central body fat distribution. Sympathetic activity was related to body temperature regulation capacity after a meal, but was not related to adiposity in normal weight young women. (Korean J Nutrition 31(7) 1130-1138, 1998)

• 대한의생명과학회지
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• 제22권4호
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• pp.167-173
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• 2016

The broth microdilution technique used to measure the minimal inhibitory concentration (MIC) of natural compounds against bacteria is problematic: it is difficult to visualize bacterial growth due to the color of the natural compound. Therefore, the use of a colorimetric method with a redox indicator by broth microdilution can simplify it and increase its objectivity. This study evaluated the usefulness of the colorimetric method in measuring the MIC of Phellinus baumii against methicillin-resistant Staphylococcus aureus (MRSA). The inhibition in disc diffusion method was observed from $8,192{\mu}g/mL$ P. baumii in all 10 MRSA isolates examined; however, the MIC ranges of the 10 MRSA isolates was $512{\sim}2,048{\mu}g/mL$ by broth microdilution using a colorimetric method; with the 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) indicator. In addition, the MIC of P. baumii by broth microdilution using MTT as indicator yielded excellent results. However, the 2, 3, 5-triphenyltetrazolium chloride (TTC) results could not be determined due to the color of the TTC indicator. The MICs of four antibiotics against MRSA using MTT or TTC were equal to those determined by visual interpretation. In conclusion, to evaluate the antibacterial effects of a natural compound, the broth microdilution technique is considered to be better than the disc diffusion method. Moreover, to resolve the problems caused by the colors of natural compounds, a colorimetric method such as that using MTT may be very valuable.

• 한국가스학회지
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• 제27권2호
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• pp.32-38
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• 2023

수도권 내 화학공장에서 부식성 유체를 펌프로 저장탱크에 공급하던 도중 수위파악이 정확히 되지 않아 상부 배기벤트로 부식성유체가 누출되는 사고가 발생하였다. 누출 사고가 발생한데는 다양한 원인이 있지만 직접 원인인 레벨게이지의 수위 지시계가 고착되는 것에 초점을 맞추었다. 분석 결과 사고가 발생한 사업장에서 사용되는 수위 지시계를 임의로 교체하였으며, 사고발생인 여름에 Tubular 방식의 레벨게이지는 열팽창이 쉽게 일어나서 다른 형태보다 고착이 발생될 수 있는 것으로 파악되었다. 또한 국내에는 저장탱크에 설치되는 계측기기의 설치기준이 명확치 않아 적정설치 검토에 어려움이 있었다. 따라서 본 연구에서는 사고사례 및 해외기준을 바탕으로 저장탱크 계측기기류 설치 시 유의사항에 대해 검토하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1865-1871
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• 2015

While health information-seeking behavior as an indicator of health communication of patients including cancer survivors has been researched, few studies have focused on how socioeconomic position and media use combine to influence health-related information seekers. This study examined social characteristics of health information-seeking behavior taking into account an individual's socioeconomic position and their media use in Korea, a developed country. The data for this study came from a survey of 1,010 respondents drawn from a nationally representative sample in the Republic of Korea. We conducted multivariate logistic regression analyses for gender-specific effects. We found that men who reported high household income were one and half times more likely to seek health information than those with low income status. We also found that women who performed Internet searches by computer at home were almost two times more likely to seek health information than those who did not. Similar results were found for men as well. Our analyses revealed that socioeconomic position and media use are associated with health information-seeking behavior by gender. Studies on information seekers may bring us more effective health promotion and relevant intervention for people with chronic conditions including cancer survivors.

• 한국병원경영학회지
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• 제24권4호
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• pp.43-56
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• 2019

Purpose: Importance of patient satisfaction related to patient-centeredness has been emphasized, and it is known to have effect on various health outcomes including health resource utilization. However, the effect of patient satisfaction has been discussed mostly in terms of hospital marketing in Korea. This study aims to examine the effect of patient satisfaction in patient-physician communication on healthcare utilization in a nationally representative adult population of South Korea. Method: Patient satisfaction with physician communication is assessed using 4 items in the 2011 Korea Health Panel Survey. Generalized linear regression analysis is conducted using 9,325 adults' healthcare utilization in 2012. Findings: Adjusting for the socio-demographic, economic factors, individual health status, health behaviors and healthcare utilization in 2011, more satisfied individuals, more likely to utilize the outpatient service, especially in clinical setting. Practical Implications: The study findings suggests that in context of South Korea healthcare system such as insufficient medical consultation time and the absence of health delivery system, patient satisfaction as a subjective healthcare quality indicator would have effect on the individual's outpatient visit. This study contributes to stimulate patient satisfaction research and discussion in South Korea to further explore its relationship with potential and various health related outcomes. Further implications of the study are discussed.

• Safety and Health at Work
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• 제8권1호
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• pp.1-10
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• 2017

Considerable effort has been made to address the issue of occupational health and environmental exposure to mercury. This review reports on the current literature of mercury exposure and health impacts on dental personnel. Citations were searched using four comprehensive electronic databases for articles published between 2002 and 2015. All original articles that evaluated an association between the use of dental amalgam and occupational mercury exposure in dental personnel were included. Fifteen publications from nine different countries met the selection criteria. The design and quality of the studies showed significant variation, particularly in the choice of biomarkers as an indicator of mercury exposure. In several countries, dental personnel had higher mercury levels in biological fluids and tissues than in control groups; some work practices increased mercury exposure but the exposure levels remained below recommended guidelines. Dental personnel reported more health conditions, often involving the central nervous system, than the control groups. Clinical symptoms reported by dental professionals may be associated with low-level, long-term exposure to occupational mercury, but may also be due to the effects of aging, occupational overuse, and stress. It is important that dental personnel, researchers, and educators continue to encourage and monitor good work practices by dental professionals.

• 응용통계연구
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• 제27권7호
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• pp.1243-1255
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• 2014

본 연구에서는 업종에 따른 다양한 근로환경 요인들을 파악하고 관련 분야의 산업안전보건 정책을 판단할 수 있도록 근로환경조사 기초자료를 분석하여 사회요인을 고려한 지수 및 지표 개발을 목표로 하였다. 지표개발을 위해 OECD에서 제시하는 지표개발 가이드라인과 해외의 지표개발 사례들을 벤치마킹하여 수행되었다. OECD의 압력-상태-대응 모형을 벤치마킹하여 건강과 관련 있는 지표들을 제시하였다. 근로환경조사의 압력-상태 건강관련 지표는 압력은 물리적 위험환경, 노동시간, 업무환경, 사회 환경으로 구성되었고, 이에 따른 상태 항목은 건강관련 항목으로 정신건강, 신체건강, 건강문제로 인한 결근, 업무 만족으로 구성되었다. 그 결과 임금근로자, 상용근로자, 관리자, 사무종사자, 전문가 및 관련 종사자, 50세 미만 근로자의 압력-상태 지표가 상대적으로 양호하였다. 반대로, 50세 이상, 자영업자, 일용 직, 농림어업 숙련직, 단순노무, 장치 기계 조립 근로자의 압력-상태 지표가 상대적으로 취약한 것으로 나타났다.

• 환경영향평가
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• 제29권2호
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• pp.93-111
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• 2020

현행 국내 건강영향평가는 환경영향평가제도 내 특정 개발사업에 한해서 수행된다. 하지만 건강영향평가가 개발사업의 시행 단계에서 수행됨에 따라 심각한 건강 악영향이 예상됨에도 불구하고 적절한 조치를 취하지 못하는 경우가 있다. 특히 산업단지 개발사업의 경우에 운영으로 인한 건강 악영향 예상 및 개발단계에서의 건강영향평가로 인해 환경갈등이 자주 발생하고 있다. 이 연구는 산업단지 개발에 있어 건강영향을 고려한 계획 적정성 평가 방법을 제안하고 이를 실제 개발사업들에 적용하고자 하였다. 이 연구는 US EPA의 CalEnviroScreen 3.0 및 US ATSDR의 Public Health Assessment를 참조해서 건강영향을 고려한 계획 적정성 평가 방법을 제안하였다. 평가 방법으로는 지역사회 특성, 배경노출, 그리고 개발부담으로 구분한 지표 사용을 제안하였다. 문헌조사 등을 통해 지역사회 특성 지표 5개, 배경노출 지표 3개, 개발부담 지표 7개를 선정하였으며, 건강영향평가 관련 전문가들에게 계층적 의사결정법 설문조사를 통해 각 지표의 가중치를 산출하였다. 과거 국가 주도의 3개 국가산업단지 개발사업에 대해 시범 적용하였으며, 이를 통해 각 지표들에 대한 활용자료 및 평가값을 세분화하여 평가 방법을 구체화하였다. 건강영향을 고려한 계획 적정성 기준은 산업단지 개발에 대한 정부의 정책방향과 연계하여 첫째 총점기준, 둘째 총점 및 지역사회 특성기준, 그리고 개발부담 지표에 예외를 둔 총점 및 지역사회 특성기준으로 제안하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제28권9호
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• pp.1217-1225
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• 2015

Chicken is a major food source for humans, hence it is important to understand the mechanisms involved in nutrient absorption in chicken. In the gastrointestinal tract (GIT), the microbiota plays a central role in enhancing nutrient absorption and strengthening the immune system, thereby affecting both growth and health of chicken. There is little information on the diversity and functions of chicken GIT microbiota, its impact on the host, and the interactions between the microbiota and host. Here, we review the recent metagenomic strategies to analyze the chicken GIT microbiota composition and its functions related to improving metabolism and health. We summarize methodology of metagenomics in order to obtain bacterial taxonomy and functional inferences of the GIT microbiota and suggest a set of indicator genes for monitoring and manipulating the microbiota to promote host health in future.