• 제목/요약/키워드: Health Gap

검색결과 641건 처리시간 0.026초

Inverse behavior of IL-23R and IL-17RA in chronic and aggressive periodontitis

  • Ruiz-Gutierrez, Alondra del Carmen;Rodriguez-Montano, Ruth;Pita-Lopez, Maria Luisa;Zamora-Perez, Ana Lourdes;Guerrero-Velazquez, Celia
    • Journal of Periodontal and Implant Science
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    • 제51권4호
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    • pp.254-263
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    • 2021
  • Purpose: Periodontitis is associated with a dysbiosis of periodontopathic bacteria, which stimulate the interleukin (IL)-23/IL-17 axis that plays an essential role in the immunopathogenesis of this disease, leading to alveolar bone destruction through receptor activator of nuclear factor κB ligand (RANKL). IL-23 receptor mRNA (IL-23R) has been identified in periodontitis, and IL-17 receptor A mRNA (IL-17RA) and its protein have not yet been evaluated in patients with periodontitis. In this study was measure IL-23R and IL-17RA in gingival tissue (GT) from patients with generalized chronic periodontitis (GCP) and generalized aggressive periodontitis (GAP) and to explore correlations with clinical parameters. Methods: We included 16 healthy subjects (HS), 18 patients with GCP, and 14 with GAP. GT samples were collected during periodontal surgery. Both IL-23R and IL-17RA were detected by enzyme-linked immunosorbent assay. Results: The results were analyzed with Mann-Whitney U test and Spearman' rank correlation coefficients using SPSS version 25.0. We found lower IL-23R levels in patients with GCP and GAP than in HS. Contrarily, we observed higher IL-17RA levels in GCP and GAP patients than in HS. Moreover, we found negative correlations between IL-23R in GT and probing depth and clinical attachment loss (CAL). Likewise, a positive correlation of IL-17RA in GT with CAL was found. Conclusions: The results of these findings suggest that the reverse behavior between IL-23R and IL-17RA in periodontitis patients may also be involved with the activation of RANKL, which promotes alveolar bone loss.

Evaluation of the marginal and internal gaps of three different dental prostheses: comparison of the silicone replica technique and three-dimensional superimposition analysis

  • Park, Jin-Young;Bae, So-Yeon;Lee, Jae-Jun;Kim, Ji-Hwan;Kim, Hae-Young;Kim, Woong-Chul
    • The Journal of Advanced Prosthodontics
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    • 제9권3호
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    • pp.159-169
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    • 2017
  • PURPOSE. The purposes of this study were to evaluate the marginal and internal gaps, and the potential clinical applications of three different methods of dental prostheses fabrication, and to compare the prostheses prepared using the silicone replica technique (SRT) and those prepared using the three-dimensional superimposition analysis (3DSA). MATERIALS AND METHODS. Five Pekkton, lithium disilicate, and zirconia crowns were each manufactured and tested using both the SRT and the two-dimensional section of the 3DSA. The data were analyzed with the nonparametric version of a two-way analysis of variance using rank-transformed values and the Tukey's post-hoc test (${\alpha}=.05$). RESULTS. Significant differences were observed between the fabrication methods in the marginal gap (P < .010), deep chamfer (P < .001), axial wall (P < .001), and occlusal area (P < .001). A significant difference in the occlusal area was found between the two measurement methods (P < .030), whereas no significant differences were found in the marginal gap (P > .350), deep chamfer (P > .719), and axial wall (P > .150). As the 3DSA method is three-dimensional, it allows for the measurement of arbitrary points. CONCLUSION. All of the three fabrication methods are valid for measuring clinical objectives because they produced prostheses within the clinically acceptable range. Furthermore, a three-dimensional superimposition analysis verification method such as the silicone replica technique is also applicable in clinical settings.

실내외 압력 차에 따른 단창과 이중창의 틈새로 침투된 간접흡연의 입자 크기 분포 특성 (Characterization of Particle Size Distribution of Infiltrated Secondhand Smoke through the Gap in a Single Glazed and a Secondary Glazed Window by Indoor and Outdoor Pressure Differences)

  • 김정훈;이기영
    • 한국환경보건학회지
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    • 제44권4호
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    • pp.360-369
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    • 2018
  • Objectives: Outdoor tobacco smoke can penetrate into the indoor environment through cracks in the building envelope. This study aimed to characterize the particle size distribution of infiltrated secondhand smoke (SHS) through the gap in a single glazed and a secondary glazed window according to pressure differences in a chamber. Methods: Two polyvinyl chloride sliding windows were evaluated for infiltration, one with a glazed window and the other with a secondary glazed window. Each window was mounted and sealed in a polycarbonate chamber. The air in the chamber was discharged to the outside to establish pressure differences in the chamber (${\Delta}P$). Outdoor smoking sources were simulated at a one-meter distance from the window side of the chamber. The particle size distribution of the infiltrated SHS was measured in the chamber using a portable aerosol spectrometer. The particle size distribution of SHS inside the chamber was normalized by the outdoor peak for fine particles. Results: The particle size distribution of SHS inside the chamber was similar regardless of window type and ${\Delta}P$. It peaked at $0.2-0.3{\mu}m$. Increases in particulate matter (PM) concentrations from SHS infiltration were higher with the glazed window than with the secondary glazed window. PM concentrations of less than $1{\mu}m$ increased as ${\Delta}P$ was increased inside the chamber. Conclusions: The majority of infiltrated SHS particles through window gap was $0.2-0.3{\mu}m$ in size. Outdoor SHS particles infiltrated more with a glazed window than with a secondary glazed window. Particle sizes of less than $1{\mu}m$ were associated with ${\Delta}P$. These findings can be a reference for further research on the measurement of infiltrated SHS in buildings.

시멘트 공간이 캐드캠 시스템으로 제작한 지르코니아 수복물의 변연과 내부 적합도에 미치는 효과 (Effect of cement space on the marginal and internal fit of zirconia restorations fabricated by CAD/CAM system)

  • 이정환;안재석
    • 대한치과기공학회지
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    • 제39권4호
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    • pp.235-242
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    • 2017
  • Purpose: The aim of this study was to evaluate the marginal and internal gap of zirconia copings fabricated by CAD/CAM system and to research the effect of cement space on the fit of zirconia prosthesis. Methods: Zirconia copings were designed using 3shape software and then milled from presintered zirconia blocks by Kavo dental milling machine. The cement space was set at $0{\mu}m$ around the margins for all groups, and additional cement space appling 1 mm above the finish lines of tooth. The samples were classified into 4 groups according to the cement space setting(Cs-0, Cs-40, Cs-80, Cs-120). Replica technique used to investigate marginal and internal gap. The silicone film thickness was recorded using a optical microscope with image software analysis system at 75${\times}$magnification. The assessment performed on the six points in bucco-lingual and mesio-distal sections(4 groups, 10 copings per group, 12 measuring points per coping). The data were statistically analyzed with one-way ANOVA followed by pair-wise Tukey's post hoc tests(${\alpha}$<0.05). Results: Better marginal and internal fit values were exhibited by $80{\mu}m$ cement space. The results showed that different cement space values had statistically significant effect on the marginal and internal gap of zirconia copings(p<0.001). The gap of margin and axial wall area was smaller than that the gap of occlusal area in all groups(p<0.001). Conclusion : Effect of different cement spaces on the marginal and internal gap of zirconia copings.

Cement Gap에 따른 Zirconia Crown의 파절강도 비교 (A Study on the Fracture Strength of the Cement Gap)

  • 김남중;이청재;곽운선
    • 대한치과기공학회지
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    • 제38권4호
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    • pp.299-304
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    • 2016
  • Purpose: This research is conducted for better clinical test of Zirconia as we find out the fracture strength difference of Zirconia on cement gaps of full Crown that made use of Zirconia which is somewhat being used in recent dental technology. Methods: We produced each nine of Zirconia Crown of Zirconia fracture cement gaps A group(0.03 mm), B group(0.05 mm), C group(0.08 mm) on cement gaps by use of CAD/CAM, and compared the results. We could end up getting conclusions as following. Results: There was fracture strength difference per cement gaps but no impact(P<0.05). There was difference between $1.962{\pm}0.259$ from group A and $2.005{\pm}0.367$ from group B, but no impact(P<0.05). There was difference between $1.962{\pm}0.259$ from group A and $2.478{\pm}0.331$ from group C, but it's hard to be considered as an impact(P<0.05). Conclusion: Because of the hight pressure 0.08 mm is fractured and Margin has a lot of empty space due to gap for 0.08 mm. To identify the difference between 0.08 mm and 0.05 mm, 0.08 mm is selected as a gap. Therefore when it comes to using 0.05 mm authentically 0.05 mm is quite practical to use as a gap.

노인의 연령 정체감, 노인에 대한 태도, 자아존중감 간의 관계 연구 (The Study on the relationships between age-identity, Attitude toward the elderly and self-esteem of the elderly)

  • 이신숙
    • 한국생활과학회지
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    • 제22권1호
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    • pp.57-74
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    • 2013
  • The purpose of this study was to identify how age-identity is associated with the attitude toward the elderly and self-esteem of the aged. The subjects were 366 adults aged 60 and over. The statistics used for the data analysis were reliability test, frequency, percentage, mean, standard deviation, one way ANOVA, correlation and multiple regression. The results of this study were as follows; First, The majority of elderly acknowledged psychological ages as their actual ages. Secondly, The degrees of elderlys' age-identity was 2.12, and the levels of the attitude toward the elderly was 60.62. Also, The degrees of elderlys' self-esteem was 24.16. The surveyed data showed higher means than medians. Third, The age-identity of elderly was significant with respect to spouse, religion, career, living state, sex, age, gap of actual age, health state, economic state, education, monthly living expenses. And the attitude toward the elderly was stastically significant with respect age-identity, career, spouse, religion, living state, health state, education, monthly living expenses, economic state, gap of actual age, and age. Moreover, The elderlys' self-esteem level was significant with respect to spouse, age-identity, living state, religion, career, economic state, monthly living expenses, the attitude toward the elderly, health state, education, and age. Finally, The variables affecting the age-identity of elderly were health state, economic state, religion, age that explained about 34% of the total variance. And The attitude toward the elderly were age-identity, health state, gap of actual age that explained about 19% of the total variance. Also, The variables that affect elderlys' self-esteem were economic state, age-identity, the attitude toward the elderly, sex, monthly living expenses that explained about 33% of the total variance.

Extraoral scanner와 intraoral scanner를 이용하여 제작된 zirconia crown의 2차원 변연 및 내면 적합도 비교: in vitro (Comparison of 2-dimensional marginal and internal fitness for the monolithic zirconia prosthesis using intraoral scanner and extraoral scanner: in vitro)

  • 이태희;이하빈;김지환
    • 대한치과기공학회지
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    • 제41권3호
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    • pp.187-193
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    • 2019
  • Purpose: The purpose of this study was to compare two-dimensional fitness of the monolithic zirconia prosthesis by using different type of scanner. Methods: No. 26 abutment tooth of FDI system was selected for the study. Using the extraoral scanner and intraoral scanner, the abutment tooth was scanned 10 times and the scanned files were saved as STL files. CAD/CAM system was used to produce the monolithic zirconia prosthesis. marginal and internal gap of the monolithic zirconia prosthesis were measured by digital microscope(x160) and applied silicone replica technique was applied. t-test, a statistical software, was used to perform data analysis. Results: Marginal gap $mean{\pm}SD$ of the monolithic zirconia prosthesis was $33{\pm}7.5{\mu}m$ with extra oral scanner and $34.7{\pm}11.1{\mu}m$ with intraoral scanner. axial gap mean was $40.5{\pm}3.5{\mu}m$ with extra oral scanner and $44.6{\pm}11.6{\mu}m$ with intraoral scanner. occlusal gap mean was $110.1{\pm}25.4{\mu}m$ with extra oral scanner and $64{\pm}9.7{\mu}m$ with intraoral scanner. Conclusion: In this study, fabricating zirconia prosthesis with different type of scanner was clinically applicable.

영유아 어머니의 국적이 영유아 건강검진 완전 수검에 미치는 영향 (The Effect of Mothers' Nationality on the Complete Health Screening of Infants and Children)

  • 서미경;정재연;윤인혜;정형선
    • 한국병원경영학회지
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    • 제26권3호
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    • pp.43-55
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    • 2021
  • Purposes: The purpose of this study is to confirm the effect of mother's nationality on screening rates for infants and children health screening. We intend to find out if there is a difference in health level between infants of multicultural families and infants of domestic families, and contribute to policies to enhance future national health levels by providing information on them. Methodology: Data for those who received the first infant and children health screening between 2012 and 2018 were obtained from the National Health Insurance Service(NHIS) DB. Frequency analysis, chi-square test and logistic regression analysis were performed with the SAS 9.4 program, and the case where all the 1st to 3rd checkups were completed was defined as type I, and the case of all the 1st to 7th checkups completed, type II. Findings: Complete screening rates for type I and type II were 45.8% and 20.0%, respectively. Especially, complete screening rate of infants whose mothers nationality is foreign is only 3-4th of that of domestic mothers, and it also differed according to nationality. Practical Implications: The difference in the screening rate according to the mother's nationality is likely to lead to a health gap between multicultural families and domestic families. It is necessary to promote and encourage proper monitoring and health management through continuous health screening for infants and children.

치료 가능한 사망으로 측정한 우리나라 지역 간 건강수준의 격차 (Regional Gaps in Health Status Estimated by Amenable Mortality Rate in Korea)

  • 백세종;김희년;이다호;정형선
    • 보건행정학회지
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    • 제31권1호
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    • pp.100-113
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    • 2021
  • Background: This study aims to figure out the gaps in health status by estimating amenable mortality rate by region, reflecting the characteristics of Korea, and estimating the years of life lost (YLL) per capita by disease. Methods: People who died from amenable diseases between 2008 and 2018 were extracted from the cause of death statistics provided by Statistics Korea. The age-standardized amenable mortality rates were estimated to compare the health status of 229 regions. YLL per capita was calculated to compute the burden of diseases caused by treatable deaths by region. The YLL per capita by region was calculated to identify the burden of disease caused by amenable deaths. Results: First, while the annual amenable mortality rate in Korea is on a steady decline, but there is still a considerable gap between urban and rural areas when comparing the mortality rates of 229 areas. Second, YLL per capita due to the amenable deaths is approximately 14 person-years during the analysis period (2008-2018). Conclusion: Although the health status of Koreans has continuously improved, there is still a gap in health status region by region in terms of amenable mortality rates. Amenable death accounts for a loss of life equivalent to 14 person-years per year. Since the amenable mortality rate is an indicator that can measure the performance of the health care system, efforts at each local area are required to lower it.