• Natural Product Sciences
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• 제9권2호
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• pp.102-104
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• 2003

Aqueous and ethanolic extract of leaves of Canthium parviflorum were evaluated for wound healing and diuretic activities. Extract in the form of ointment is applied topically on excision wound in rats showed significant healing process as evidenced by increased rate of wound contraction as compared to control. The aqueous extract of 10% w/w ointment exhibited equivalent wound healing activity as Nitrofurazone oinment. Significant diuretic activity was exhibited by extracts. Graded dose response for both activities were observed for the extracts.

• 한국산학기술학회논문지
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• 제21권7호
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• pp.54-65
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• 2020

본 연구는 경막외강차단 시술 후 Healing Beats 프로그램 적용하였을 때 환자의 불안, 스트레스, 수축기 혈압, 심박동수 및 Bis index에 미치는 효과를 확인하기 위한 무작위 대조군 전후 실험연구이다. 대상자 선정은 경막외강차단 시술을 위해 2018년 12월부터 2019년 5월까지 마취통증의학과를 방문하여 모집공고를 통해 자원한 환자를 대상으로 하였으며, 실험군 25명, 위약군 24명, 대조군 25명으로 총 74명의 자료를 수집하여 분석하였다. 수집된 자료는 x2-test, F-test와 시간에 따른 효과를 검증하기 위하여 repeated measures of ANOVA로 반복측정 분산분석하였다. 연구결과 실험군, 위약군 및 대조군의 일반적 특성 및 변수는 모두 동질하였으며, 불안은 사전 사후 2회 측정한 결과 집단간 유의한 차이가 있었고(F=27.175, p<.001), 스트레스(F=4.78, p<.001), 심박동수(F=4.22, p<.001) 및 Bis index(F=7.96, p<.001)는 반복측정 분산분석한 결과 집단과 시간에 따라 교호작용에서 유의한 차이를 나타냈다. 하지만 수축기 혈압에서는 유의한 차이가 없었다(F=1.23, p=.298). 따라서 Healing Beats는 통증 시술 후 회복실에서 진정을 유도하기 위한 간호 중재로 효과적이며, 시간 흐름에 따른 추적 조사를 통해 중재 시간을 파악할 수 있었다. 결론적으로 Healing Beats 프로그램은 임상현장이나 일상생활의 스트레스 상황에서 진정을 위한 효율적, 효과적인 중재로 사용할 수 있다고 본다.

• Earthquakes and Structures
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• 제16권6호
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• pp.727-741
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• 2019

A reinforced concrete water tank is a typical functional liquid storage structure and cracks are the greatest threat to the liquid storage structure. Tanks are readily cracked due to seismic activity, thereby leading to the leakage of the stored liquid and a loss of function. In order to study the effect of cracks on liquid storage tanks, self-healing and leakage tests for bending cracks and through cracks in the walls of a reinforced concrete water tank were conducted. Material performance tests were also performed. The self-healing performance of bending cracks in a lentic environment and through cracks in a lotic environment were tested, thereby the self-healing width of bending micro-cracks in the lentic environment in the short term were determined. The through cracks had the capacity for self-healing in the lotic environment was found. The leakage characteristics of the bending cracks and through cracks were tested with the actual water head on the crack. The effects on liquid leakage of the width of bending cracks, the depth of the compression zone, and the acting head were determined. The relationships between the leakage rate and time with the height of the water head were analyzed. Based on the tests, the relationships between the crack characteristics and self-healing as well as the leakage were obtained. Thereby the references for water tank structure design and grading earthquake damage were provided.

• The Journal of Korean Physical Therapy
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• 제23권1호
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• pp.45-51
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• 2011

Purpose: This study investigated the effect of needle electrode stimulation at various frequencies on change in wound healing in excision wound rats Methods: Twenty-four Sprague-Dawley adult male rats were assigned to one of four groups: control (n=6), acupuncture group (n=6), low rate (2 Hz) percutaneous electrical stimulation group, high rate (100 Hz) percutaneous electrical stimulation group (n=6). We analyzed morphological effects by measuring the area of the excision wound, the contraction rate, and chromatic red. A digital camera and an image analysis program were used to measure and analyze the wound area,which was also used for the contraction rate. Chromatic red was obtained by calculating red, green, and blue (RGB) values of the wound area. Results: The electro acupuncture stimulation groupsshowed significant healing effects compared to the control and acupuncture groups. Conclusion: The results of this study showed that various frequencies of percutaneous electrical stimulation have a therapeutic effect on wound healing.

• 농업과학연구
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• 제44권3호
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• pp.451-461
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• 2017

Korean agriculture has recently focused on the 6th dimension of industrialization, which includes the functions of healing and care. The green care and healing business is one of the most representative models, satisfying modern consumers' needs for care or healing in rural agricultural environments. Many studies have shown physical and social benefits from green care and healing, but studies regarding economic performance are rarely found. The present study aimed to analyze the economic feasibility of different green care and healing farm complexes proposed in recent domestic research, with various possible combinations of business scenarios. The results show that most of the scenarios are economically feasible as B/C (benefit-cost ratio) and IRR (internal rate of return) are 1.19 and 8.53%, respectively, under scenario 1. This study also performed a break-even analysis for providing more flexible decision-making information. Overall, scenario 1 from green care and healing site and scenario 4 from green care and healing cluster are found to be superior to the other scenarios in terms of B/C and IRR. The scenarios in this study reflect the domestic farms or complexes which have similar functions of care or healing. Therefore, the results of this study provide information on practical policies and business implications in making decisions on the specific size and operational patterns when adopting green care and healing complexes by central or local governments and private sectors in the future.

• 공학교육연구
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• 제21권6호
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• pp.25-34
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• 2018

The low growth rate and the high youth unemployment rate that our society faces have already come to our country core problem. Today, as we enter the era of the Fourth Industrial Revolution, the social atmosphere that urgently needs to solve the problem of youth employment has become imminent, and the importance of university-industry cooperation is increasingly emphasized. In this paper, in this paper, we explore the process of how to develop fusion multifaceted curriculum centered on the Konkuk University College of Healing Bio Sciences Consortium Focus, which is developed and operated through literature review and Delphi questionnaire, The purpose of this study is to propose the conditions for enhancing educational suitability and the expansion of interdisciplinary convergence education.

• Animal cells and systems
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• 제16권6호
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• pp.469-478
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• 2012

Sex hormones have long been considered to play an important role in bone turnover rate, periodontal diseases, and wound healing. We have studied the effect of porcine testis steroid extract (PTSE), an extract of porcine testes, which holds a good ratio of 19-nortestosterone (nandrolone), testosterone, androstenedione, $17{\beta}$-estradiol, and estrone, on the healing rate of a standardized full-thickness linear wound on the back of the rat. Skin punch or carbon dioxide ($CO_2$) laser methods were used to create the deep skin injury in two groups of animals. The animals were treated with the PTSE cream, control cream and Vaseline (control) to find out the effect in re-epithelialization, contraction, and formation of granulation and scar tissues. Histological examination after 21 days showed 100, 87.4, and 80.5% recovery of epidermis, dermis, and hypodermis, respectively in the PTSE-treated animals. Similarly, on the 15th day of treatment, complete healing of intact skin was observed in the PTSE cream-treated animals among the laser radiation group. Even though the beginning of re-epithelialization phase and completion of serum crust formation was also observed in the base cream- and Vaseline-treated animals respectively, the complete healing cycle was observed only in the PTSE-treated group. The white blood cell count in the PTSE-treated group showed that PTSE cream is nontoxic to animals.

• 한국건설순환자원학회논문집
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• 제10권4호
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• pp.584-592
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• 2022

본 논문에서는 구체방수 혼화재로 사용되는 아세트산나트륨을 활용하여 자기치유 성능 향상 및 강도 성능 개선을 위한 연구를 진행하였다. 선행연구로 개발된 유ㆍ무기계 자기치유 핵심소재와 재생 아세트산나트륨을 혼합 제조하여 자기치유 모르타르, 콘크리트의 기초성능 및 투수 저감 성능을 평가하였다. 재생 아세트산나트륨을 첨가 실험결과 무수화물 단독으로 사용한 배합에 비해 무수화물과 삼수화물을 7:4 비율로 혼합한 소재의 압축강도 개선 효과가 3~7 %로 확인되었다. 또한, 최대 투수감소율은 92.6 %로 자기치유 특성을 만족하는 결과를 확인하였다.

• 한국임상수의학회지
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• 제20권2호
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• pp.198-206
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• 2003

The purpose of the present study was to investigate the effect of polyphosphate on healing of skin wound in rabbits. Four skin wounds of 8mm in diameter were induced bilaterally(4 wounds/rabbit) on the dorsolateral aspect of the trunk of 15 male New Zealand white rabbits. Ten percent polyphosphate(poly P) type 25, 10% poly P type 35, 10% poly P type 25+10% poly P type 35 and 0.85% sterile saline solution were applied on the wound area and examined grossly and histopathologically. The rate of wound contraction and histopathological changes after poly P application on the skin wound were investigated. In gross findings, the wound contraction rates of 10% poly P 25 group were significantly decreased from day 2 to day 7 after operation than those of 0.85% sterile saline solution treated group (p < 0.01). Although the hemorrhage and inflammation were observed on days 3, 6 and 9 after operation in all groups, but in 10% poly P 25 was gradually decreased. Revascularization and reepithelialization were seen 3, 6 and 9 days after operation in all groups, especially in 10% poly P 25 was formed completely on 9 days. Fibroplasia were seen 3. 6 and 9 days after operation in all groups, especially in 10% poly P 25 was compact than other groups on 9 days. The results suggested that polyphosphate, especially 10% poly P 25 would be effective on healing of skin wound in rabbits through decrease of would contraction rate, increase of revascularization, reepithelialization and fibroplasia.

• 한국임상수의학회지
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• 제27권4호
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• pp.382-385
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• 2010

This study was performed to investigate the wound healing effects of Allium cepa L. on Staphylococcus intermedius contaminated wound. 4 full-thickness skin wounds ($2\;cm{\times}2\;cm$) were made in the back and Staphylococcus intermedius was inoculated in seven dogs. In each dog, the wounds were treated with onion extract (experimental group) and normal saline (control group), respectively. The wound contraction rate of the experimental group was higher than that of the control group during the experimental period. The occupation rate showed that the wounds of the experimental groups contracted more vigorously than that of the control group in the early period of wound healing. The mean value of tensile strength on the 22 day after wounding was $4,741{\pm}848\;g/cm^2$ in the experimental group and $2,400{\pm}397\;g/cm^2$ in the control group. The number of S. intermedius in the experimental groups was decreased more rapidly than that of the control group. These results suggest that application of activated onion extract in like full-thickness skin wounds promote wound healing.