• 셀메드
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• 제13권10호
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• pp.12.1-12.4
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• 2023

The purpose of this study is to suggest that compassion is used as a mechanism to improve immunity by activating people's parasympathetic nerves. Compassion is pity and heartbreak for the misfortune of others. The instinctive emotion of compassion is the basis for humans to achieve and develop society. This is also linked to the laws of nature and the factors of evolution that Kropotkin, famous for his "mutual assistance (mutualism)" that all things help each other. Compassion is an individual's instinctive emotion and at the same time a driving force for forming and developing society. If the Hopeful World (希望世上) performs Korean traditional music healing at a nursing home, first, it will have a positive healing effect on the elderly in the nursing home, who are the audience. Second, positive healing effects can also be expected from performers. The stronger the compassion, the greater the healing effect. Third, people who watch the performance also enjoy the healing effect. This seems to have brought about a synergistic effect by combining the feelings felt while looking at the excellent behavior felt by seeing the poor person. It seems that this effect can be named the compassion effect that developed the Mother Teresa effect. The Mother Teresa effect refers to a significant improvement in the body's immune function just by volunteering or seeing good things. By expanding this Mother Teresa effect, it can be inferred that a pitying heart, helping behavior, and being with good behavior will all help improve the human immune system. This can also be called the compassion effect. Therefore, we think having compassion activates the parasympathetic nerves, improving your mood, and increasing your immunity.

• Journal of Ginseng Research
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• 제47권4호
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• pp.493-505
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• 2023

In recent years, an increasing number of reports have explored the wound healing mechanism of these two traditional Chinese herbal medicines- Panax ginseng and Panax notoginseng, but there is no systematic research on the related core functions and different mechanisms in the treatment of wound healing up to now. Based on network pharmacology and meta-analysis, the present work aimed to comprehensively review the commonality and diversity of P. ginseng and P. notoginseng in wound healing. In this study, a wound healing-related "ingredients-targets" network of two herbs was constructed. Thereafter, meta-analysis of the multiple target lists by Metascape showed that these two medicines significantly regulated blood vessel development, responses to cytokines and growth factors and oxygen levels, cell death, cell proliferation and differentiation, and cell adhesion. To better understand the discrepancy between these two herbs, it was found that common signaling pathways including Rap1, PI3K/AKT, MAPK, HIF-1 and Focal adhesion regulated the functions listed above. In parallel, the different pathways including renin-angiotensin system, RNA transport and circadian rhythm, autophagy, and the different metabolic pathways may also explained the discrepancies in the regulation of the above-mentioned functions, consistent with the Traditional Chinese Medicine theory about the effects of P. ginseng and P. notoginseng.

• 인간식물환경학회지
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• 제22권5호
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• pp.425-434
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• 2019

This study was conducted to investigate psychological and physiological changes of elderly affected by agro-healing activities. To meet the purpose, we conducted an agro-healing program with 20 elderly participants (average age 77.6±5.84 men and women) and once a week in total seven sessions. The Korean version of the Brief Encounter Psychosocial Instrument (BEPSI-K), Korean version of the Short Form of Geriatric Depression Scale (SGDS-K), participants' satisfaction with the program, Salivettes system method, and blood pressure were measured to find out the effects of agro-healing activities. BEPSI-K decreased by 5% in the high stress group although it was not statistically significant. The result of program satisfaction showed that 75% of the participants are satisfied with these activities. We investigated how many and what kind of chronic diseases the participants have had before they joined the program. As a result, hypertension was most common(35.6%), followed by hyperlipidemia, diabetes, arthritis, lumbago, osteoporosis, and heart disease. Systolic blood pressure after the activities decreased significantly from 144.75mmHg (stage 1 hypertension), to 132.90mmHg(prehypertension stage). As a result of analyzing the correlations between general matters such as age, education level, average income of the participants, psychological scale and number of diseases, it was found that participants' satisfaction had a negative correlation with depression. In conclusion, agro-healing is very useful in relieving stress or lowering blood pressure for the elderly whose most common disease is hypertension. Agro-healing activities are proved to have positive uses in reducing the problems of the modern society with severe issues of the aging population.

• 한국구조물진단유지관리공학회 논문집
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• 제20권6호
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• pp.10-19
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• 2016

본 연구의 목적은 OPC, GGBFS 그리고 FA를 사용한 삼성분계 시멘트(TBC) 페이스트의 자기치유 특성에 관한 것이다. 초음파속도(UPV)측정으로 통해 삼성분계 시멘트의 자기치유 능력에 대한 OPC-GGBFS-FA의 영향을 분석하였다. TBC 페이스트는 0.5의 일정한 물-결합재 비에 GGBFS-FA를 20%, 40% 그리고 60% 치환한 배합이다. 본 연구는 재령 28일(하중 재하 후)이후의 거동에 초점을 맞추었다. 재령 28일에 휨시험을 통해 사각형의 보 시험체에 미리 균열을 발생시켰다. 시험체들은(균열을 발생시키지 않은 것과 균열을 발생시킨) 60일까지 담수와 해수에 침지하였다. 시험결과에 따르면 TBC 페이스트의 자기치유 능력은 GGBFS의 혼합률이 증가함에 따라 증가하였다. 이는 GGBFS와 FA는 재령 28일 이후에도 계속해서 수화가 진행되는데, GGBFS와 FA의 수화반응 물질들이 미세구조의 변화와 균열을 폐합한다. 이러한 결과들로부터, 균열을 발생시킨 모든 시험체에서 자기치유가 일어났고 이는 침지 30일에서 가장 많이 발생하였다. 더구나 담수와 해수에 침지한 시험체의 치유의 대부분이 침지 30일 동안 일어났다. 해수에 침지한 시험체의 균열 치유는 담수보다 빨랐다. 해수와 담수에 침지한 시험체의 치유효과의 차이는 해수에 포함된 이온들 때문이다. 더구나 재령효과를 고려한 자기치유효과는 침지 30일까지가 가장 강력하고 그다음엔 차츰 약해졌다.

• Human Ecology Research
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• 제54권6호
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• pp.631-642
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• 2016

This study analyzed of the themes (wounding and healing); concerning the Sandplay therapy process applied to children with emotional instability and attention deficit problems. The subjects of the study were 30 elementary school children who agreed to a personal-interview with the author. They all were families of receiving basic livelihood welfare living in the same county. After the preliminary analysis, the main study data collected from subjects was analyzed by variance (t-test), frequency analysis, and correlation analysis using the standard table modified in accordance with Mitchell's classification system. Particular attention was made in the analyses of the characteristics of the subjects as members of low-income families. As the Sandplay therapy proceeded, it became evident that the wounding area showed a low frequency while the healing area featured a high frequency, and confirmed (as in previous studies) that the Sandplay therapy would be effective for children with emotional instability as well as for those with attention deficit problems. The analysis of difference between the types of children with both problems revealed that Sandplay therapy was more effective for children with emotional instability than for those with attention deficit problems. The analysis also revealed that Sandplay therapy was more effective for girls than for boys.

• 한국임상수의학회지
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• 제35권3호
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• pp.83-87
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• 2018

The aim of this study was to evaluate the biomechanical behavior of xenogenic bone plate system (equine bone) using a three-dimensional finite element ulna fracture model. The model was used to calculate the Von Mises stress (VMS) and stress distribution in fracture healing periods with metallic bone plate and xenogenic bone plate systems, which are installed while the canine patient is standing. Bone healing rate (BHR) (0%) and maximum VMS of the xenogenic plate was similar to the yield strength of equine bone (125 MPa). VMS at the ulna and fracture zones were higher with the xenogenic bone plate than with the metallic bone plate at BHRs of 0% and 1%. Stress distributions in fracture zone were higher with the xenogenic bone plate than the metallic bone plate. This study results indicate that the xenogenic bone plate may be considered more beneficial for callus formation and bone healing than the metallic bon plate. Xeonogenic bone plate and screw applied in clinical treatment of canines may provide reduced stress shielding of fractures during healing.

• Journal of Acupuncture Research
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• 제18권5호
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• pp.135-146
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• 2001

Objective : Bone homeostasis is maintained by balance of bone formation and resorption. Therefore, bone related diseases arose by disturbance of this balance between osteoblast and osteoclast activities. To develop a successful screening system of the therapeutic components based on oriental medicine is essential to set out systematic approach for that purpose. Methods : This study was perforated Sprague-Dawley rat femur for bony defects(${\phi}5mm$) by the fissure bur. And experimetal group were treated with Cervi Pantotricuhum Cornu injection at both $Sh{\grave{e}}nsh{\tilde{u}}$(BL23) & $D{\grave{a}}zh{\grave{u}}(BL11)(0.2m{\ell})$. This was evaluated by radiography and histological analysis with in situ hybridization. Results : Cervi Pantotricuhum Cornu Herbal Acupuncture has weak effect on bony defect healing and this was evaluated by X-ray taking and histological analysis with in situ hybridization. Osteocalcin gene expression was not changed by Cervi Pantotricuhum Cornu Herbal Acupuncture in bony defects animal model. Conclusion : Taken together this study show that the Cervi Pantotricuhum Cornu herbal-acupuncture has a weak effect healing of bony defects, this type of approach might give a good chance to explore the favorable effects of Cervi Pantotricuhum Cornu herbal-acupuncture on bone tissue.

• 한국전기전자재료학회논문지
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• 제22권5호
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• pp.431-435
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• 2009

The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a InGaAlP laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. To raise the stimulus effect of the human body, the optical irradiation frequency could be set up. The study has executed in-vivo experiment by employing our own developed laser diode irradiation system to investigate the effects of the InGaAlP laser diode irradiation on the wound healing as a preliminary study aimed at the application of InGaAlP laser diode to wound healing of human skin injury. The study cut out whole skin layers of Sprague-Dawley rat on the back part in 1 cm circle and observed developing effects after executing light irradiation for 9 days, and in result it is found that the light irradiation rat showed earlier wound healing than non-irradiation rat during the experimental period. In addition, there are some differences found regarding the healing process between laser diode irradiated rats and non-irradiated ones.

• Journal of Photoscience
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• 제9권2호
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• pp.194-196
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• 2002

While ultraviolet radiation alters various cutaneous cell functions, little is known about photo-immunological and photobiological effects of infrared radiation (IR) on the skin except its local thermal effects. The fIrst part of this study demonstrated that single exposure of mouse skin to near IR (0.7 - 1.3 $\mu$m) reversibly suppressed the proliferating activity of the epidermis, the density of Langerhans cells, and the ability of skin to induce contact hypersensitivity reaction. The second part demonstrated that the rate of wound closure was significantly accelerated by repeated exposures in animal models. The production of transforming growth factor-$\beta$l and matrix metalloproteinase-2, which are responsible for the wound healing processes, was significantly upregulated by irradiation, as shown by enzyme immunoassay, zymography, and reverse transcription polymerase chain reaction. Thermal controls were negative. The results suggest that near-IR irradiation can modulate the epidermal proliferation and part of the skin immune system, and stimulate the wound healing processes, presumably by non-thermal effects.

• 한국CDE학회논문집
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• 제10권4호
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• pp.262-273
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• 2005

For CAD data users, few things are as frustrating as receiving CAD data that is unusable due to poor data quality. Users waste time trying to get better data, fixing the data, or even rebuilding the data from scratch from paper drawings or other sources. Most related works and commercial tools handle the boundary representation (B-Rep) shape of CAD models. However, we propose a design history?based approach for healing CAD model errors. Because the design history, which covers the features, the history tree, the parameterization data and constraints, reflects the design intent, CAD model errors can be healed by an interdependency analysis of the feature commands or of the parametric data of each feature command, and by the reconstruction of these feature commands through the rule-based reasoning of an expert system. Unlike other B Rep correction methods, our method automatically heals parametric feature models without translating them to a B-Rep shape, and it also preserves engineering information.