• Radiation Oncology Journal
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• v.38 no.2
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• pp.84-92
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• 2020

Patients undergoing radiation therapy for head and neck cancer (HNC) experience significant early and long-term side effects. The likelihood and severity of complications depends on a number of factors, including the total dose of radiation delivered, over what time it was delivered and what parts of the head and neck received radiation. Late side effects include: permanent loss of saliva; osteoradionecrosis; radiation recall myositis, pharyngoesophageal stenosis; dental caries; oral cavity necrosis; fibrosis; impaired wound healing; skin changes and skin cancer; lymphedema; hypothyroidism, hyperparathyroidism, lightheadedness, dizziness and headaches; secondary cancer; and eye, ear, neurological and neck structures damage. Patients who undergo radiotherapy for nasopharyngeal carcinoma tend to suffer from chronic sinusitis. These side effects present difficult challenges to the patients and their caregivers and require life-long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. This review presents these side effects and their management.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2003.10a
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• pp.37-37
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• 2003

Enzymes involved in catecholamine synthesis are present in the highest concentration in the adrenal medulla, however they were found also in other, mainly nervous tissues. Increased transcription of genes for catecholamine biosynthetic enzymes is an important mechanism to increase the capacity for epineprine/norepinephrine biosynthesis with stress. Gastrodia elata(Chinese name: Tienma), are very important Chinese herbal medicines used for the medical treatment of headaches, migraine, dizziness, epilepsy, rheumatism, neuralgia, paralysis and other neuralgic and nervous disorders. Immobilize stressed rat markedly increased tyrosine hydroxylase (TH) mRNA and dopamine-$\beta$-hydroxylase (DBH) mRNA transcription level more than control group. But treated Gastrodia elata extracts in immobilized stressed rat slightly increased TH mRNA and DBH mRNA transcription level more than normal group. In addition, we are obtained identical results in PC12 cell line. Decrease of transcription level of TH mRNA and DBH mRNA is indicating that Gastrodia elata have a anti-stress effects which decrease the transcription level of TH and DBH mRNA on catecholamine biosynthesis pathway.

• Investigative Magnetic Resonance Imaging
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• v.23 no.2
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• pp.172-174
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• 2019

Upon review, it is noted that recurrent painful ophthalmoplegic neuropathy (RPON) is a rare neurological syndrome characterized by recurrent unilateral headaches and painful ophthalmoplegia of the ipsilateral oculomotor nerve. As seen on brain MRI, thickening and enhancement of the oculomotor cranial nerve can be observed in these cases. We experienced a case of RPON in an adult patient who showed thickening and enhancement of the oculomotor nerve on gadolinium-enhanced 3D-FLAIR image. The authors report a case of RPON with a review of the literature.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.393.2-393.2
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• 2002

Benzodiazepine is a widely used anxiolytic agent. However it has been reported that most anxiolytics have side effects such as hypotension, depression of respiration. dizziness. headaches. chronic sleep disorders. drug poisonings. and withdrawal symptoms. In this report. we want to evaluate the anxiolytic effect of Albizia julibrissin (AJ), There are various reports that AJ has several biological activities such as sedative action. insomnia. irritability, anorexia and diuretic action. (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.390.1-390.1
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• 2002

Gastrodia elata Blume belongs to Orchidaceae, its steamed and dried rhizomes are very important herbal medicines used for the medical treatment of headaches. migraine. dizziness, epilepsy, rheumatism. neuralgia. paralysis and other neuralgic and nervous disorders. Although phytochemical studies of the rhizome have revealed the presence of several phenolic compounds. in which a phenolic glycoside. gastrodin (C13H18O7). is a major consituent, so far, there is no report on the studies of its aerial part. (omitted)

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.79.1-79.1
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• 2003

Aster scaber T. (Asteraceae) has been used in traditional Korean and Chinese medicine to treat bruises, snakebites, headaches and dizziness. (-) 3,5-Dicaffeoyl-muco-quinic acid (DQ) isolated from Aster scaber induced neurite outgrowth in PC12 cells. It has been reported that the activation of the extracellular signal regulated kinase1/2 (Erk 1/2) and phosphoinositide 3 (P13) kinase plays a crucial role in the NGF-induced differentiation of PC12 cells. This study showed that the effect of DQ on neurite outgrowth is mediated via the Erk 1/2 and PI3 kinase-dependent pathways like NGF. (omitted)

• Journal of Trauma and Injury
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• v.35 no.2
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• pp.115-117
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• 2022

"Whiplash"-type injuries are commonly encountered and often cause neck pain, neck stiffness, and headaches. However, these injuries can have rare and poorly recognized complications, such as the development of a prevertebral hematoma leading to acute respiratory failure in the emergency department, followed by severe, life-threatening dysphagia and recurrent aspirations. In the patient described herein, a whiplash injury was accompanied by vocal cord paralysis and dysphonia (vagus nerve), dysgeusia (glossopharyngeal nerve, vagus nerve), and upper esophageal spasm (cricopharyngeal muscle, vagus nerve). It is unlikely that this was a complication of cervical fusion surgery. Instead, a combined stretch-induced lower cranial nerve injury, possibly on the exit of these nerves through the jugular foramen, seems to be a likely, but underappreciated mechanism occurring in rare instances of whiplash injuries.

• Imaging Science in Dentistry
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• v.52 no.4
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• pp.421-427
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• 2022

McCune-Albright syndrome (MAS) is a rare multisystem disorder characterized by a clinical triad of polyostotic fibrous dysplasia (FD), skin pigmentation, and hyperfunctioning endocrinopathies. A 42-year-old man visited our medical hospital for the treatment of intermittent headaches and was diagnosed with MAS with acromegaly. This patient showed various clinical features of MAS, including pituitary adenoma, polyostotic FD, and hypogonadotropic hypogonadism. The FD lesions showed characteristic radiographic features, such as widespread, sclerotic bony lesions in the cranial bones, mixed radiolucent-radiopaque multilocular lesions in the mandible, and radiolucent lesions in the axial and appendicular skeleton. Over the years, the patient had been hospitalized multiple times due to accidental bony fractures associated with the fragile bony state of FD. This report presents a retrospective description of a case of MAS, with a review of the relevant literature.

• Journal of the Korean Society of Safety
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• v.38 no.6
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• pp.16-25
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• 2023

This study investigated health problems and work-relatedness for fishermen. In total, 121 fishermen (103 males and 18 females) were extracted from the data of the 6th Korean Working Conditions Survey. Two groups (Symptomatic and Asymptomatic) were statistically compared in terms of health problems and exposure to hazards. The most common health problems identified for fishermen were muscular pain in the shoulder, neck, and upper limbs (73.6%), backache (71.1%), muscular pain in the lower limbs (58.7%), overall fatigue (33.9%), headaches or eyestrain (22.3%), and anxiety (8.3%). These health problems were found to be related to the working conditions of the fishermen (low temperatures, tiring or painful postures, stance, sitting position, repetitive hand or arm placement, and the experience of stress). This study's findings may help us better understand the characteristics of the health problems and work-relatedness of fishermen and could be helpful for improving fishermen's overall health and safety.

• Journal of Oral Medicine and Pain
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• v.48 no.4
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• pp.137-143
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• 2023

Purpose: To assess Google Trends (GT) search behavior regarding orofacial pain (OFP) and headaches. Methods: GT scores for OFP and headache specialists between February 2013 and December 2022 were analyzed. Statistical tests such as Poisson regression analyses, mean differences, and Cohen's D were used to assess the score change over time. Results: The top three search words for OFP specialists were "temporomandibular joint (TMJ) specialist," "TMJ doctor," and "TMJ dentist," whereas the top three search words for headache specialists were "Headache specialist," "Headache doctor," and "Migraine specialist." Here, TMJ is temporomandibular joint. The GT scores for OFP specialists increased significantly (p<0.05) for all years except 2017, with the highest mean difference in 2020. The scores for headache specialists showed similar trends but gradually. Conclusions: The interest in OFP and headache specialists expressed by Google searches has increased over the years. More awareness is needed regarding the OFP scope of practice, and the use of GT may serve as an indicator.