• 제목/요약/키워드: Head-ratio

검색결과 1,108건 처리시간 0.025초

원격 전이로 재발한 갑상선 유두암에 대한 임상적 고찰 (Clinical Manifestations of Papillary Thyroid Carcinoma Recurred as Distant Metastases)

  • 김남영;김경헌;박성호;이국행;이병철;이명철;최익준
    • 대한두경부종양학회지
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    • 제31권2호
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    • pp.11-15
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    • 2015
  • Background and Objectives: This study aimed to analyze the features of patients with papillary thyroid carcinoma (PTC) recurred as distant metastases (DM). Materials and Method: We retrospectively reviewed and analyzed clinical records of 63 patients who were treated for PTC recurred as DM between 2000 and 2006. Univariate and multivariate analyses of various clinical factors were performed. Results: Male patients were 12, and female patients were 51. The 5- and 10-year survival rates for PTC recurred as DM were 85% and 73%, respectively. Size of tumor, multiplicity of tumor, lateral neck node metastasis, and RAI ablation therapy with other treatments such as surgery were associated with survival rate (p < 0.005) in univariate analysis. The lateral neck node metastasis[p =0.039, hazard ratio=2.2(95% CI. 1.18~3.24)] and multiple organ DM[p =0.041, hazard ratio=2.18(95% CI. 1.03~2.89)] were related to the survival in multivariate analysis. Conclusion: PTC recurred as DM is uncommon (2.2%). The size of tumor, the multiplicity of tumor, lateral neck node metastasis and RAI ablation therapy with other treatments for DM were revealed as associated factors for the survival. Evaluation of DM should be considered in patients with PTC during long-term follow-up.

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2개층 사질토지반에서 단일 강성말뚝의 수평거동에 대한 두부 구속영향 (Effect of Pile Head Constraint on Lateral Behavior of Single Rigid Pile in Two-Layered Sand Soil)

  • 김영수;서인식;김병탁;이상웅
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 1999년도 봄 학술발표회 논문집
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    • pp.217-224
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    • 1999
  • This Paper shows the results of a series of model tests on the behavior of single rigid Pile, which subjected to lateral load, in non-homogeneous Nak-Dong River sands, consisted of two layers, upper and lower layers. The purpose of the present paper is to investigate the effect of ratio of lower layer thickness to embedded pile length ratio of soil modules of upper to lower layer (E$\sub$h1//E$\sub$h2/) and pile head constraint condition on the characteristics of lateral behavior of single pile. These effects can be quantified only by the results of model tests. As a model test result, in non-homogeneous sand, it shows that the lateral behavior depends upon the ratio of soil modules of upper to lower layer more than other factors. And, in respect of deflection, it was found that the reduction ratio of deflection by pile head fixity is the value of 0.5 and 0.6 for E$\sub$h1//E$\sub$h2/=0.18 and E$\sub$h1//E$\sub$h2/=5.56, respectively. The critical thickness of lower layer on the change of deflection is about 25 - 50% of pile embedded length. Also, in respect of maximum bending moment it was found that the reduction ratio of maximum bending moment by pile head fixity is the value of 0.55 and 0.7 for E$\sub$h1//E$\sub$h2/=0.18 and E$\sub$h1//E$\sub$h2/=5.56, respectively.

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90도 각도를 갖는 분기수로에서 모형실험결과를 이용한 손실계수 경험식 산정 (Estimation of Head Loss Coefficient Empirical Formulas Using Model Experimental Results in a 90° Angle Dividing Channel Junction)

  • 박인환;성호제;김형준;이동섭
    • 대한토목학회논문집
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    • 제37권6호
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    • pp.989-999
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    • 2017
  • 본 연구에서는 분기수로에서 발생되는 에너지손실을 계산하기 위한 손실계수의 경험식을 산정하기 위해 수리모형실험을 수행했다. 수리모형은 유입수로와 90도의 각도를 갖는 두 유출수로로 구성되어 있으며, 유입수로과 유출수로에서 압력수두와 속도수두를 측정하여 분기수로에서 발생되는 에너지손실을 분석했다. 각 측선에서 동수경사선의 변화를 비교한 결과, 수로의 분기점에서 동수경사선이 급격히 하강하여 에너지손실이 분기점에서 발생되었으며, 유량비의 증가에 따라 속도수두의 감소폭이 증가했다. 유량비와 Froude수가 증가함에 따라 유출량이 더 큰 수로에서 수두손실량이 지수적으로 증가하는 결과를 보였으며, 손실계수 또한 증가했다. 반면에, 유출량이 작은 수로에서는 유량비와 Froude수의 증가에 따라 손실계수가 감소하는 결과가 나타났다. 손실계수 계산결과를 이용하여 두 유출수로에서 손실계수 경험식을 제안하였으며, 경험식의 계산오차가 각각 3.91%, 5.19%로 나타났다. 그리고 두 경험식을 이용하여 계산한 총 손실계수를 실험결과와 비교하여 3.62%의 오차가 발생했다.

터빈 블레이드 선단에서의 샤워헤드 막냉강 - 국소분사율 측정 및 유동의 가시화 - (Shower-Head Film Cooling on the Leading Edge of a Turbine Blade: Measurements of Local Blowing Ratio and Flow Visualizations)

  • 정철희;이상우
    • 대한기계학회논문집B
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    • 제23권3호
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    • pp.419-430
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    • 1999
  • Measurements of local blowing ratio and ammonia-diazo flow visualizations have been conducted for a shower-head film cooling on a first-stage turbine stator. In this study, six rows of normal holes are drilled symmetrically on the semicircular leading edge of a simulated blunt body. The measurements show that for an average blowing ratio based on freestream velocity, M, of 0.5, local average mass flow rate through the first two rows of the holes is less than those through the second and third two rows of the holes, and the fraction of mass flow rate through the first two rows to total mass flow rate has a tendency to increase with the increment of M. The flow visualizations reveal that the injection through the first two row results in inferior film coverage even In the case of M = 0.5, meanwhile the row of holes situated at farther downstream location provides higher film-cooling performances for all tested M. This is because film-cooling effectiveness depends on local mainflow velocity at the hole location as well as the mass flow rate through each row.

무지개송어, Oncorhynchus mykiss와 산천어, O. masou간의 잡종 및 잡종 3배체 생산 II. 성비 및 계측형질 특성 (Production of Hybrid and Allotriploid between Rainbow Trout, Oncorhychus mykiss and Cherry Salmon, O masou II. Characteristics of Sex Ratio and Morphometric Traits)

  • 박인석;최경철;김동수
    • 한국양식학회지
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    • 제10권1호
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    • pp.49-54
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    • 1997
  • 무지개송어, 산천어, 무지개송어와 산천어간의 잡종 3배체를 대상으로 성비조사와 형태학적 계측형질을 측정하였다. 무지개송어, 산천어의 암.수 성비는 공히 유사한 비율로 나타난 반면, 잡종과 잡종 3배체에서는 수컷이 암컷에 비해 높게 나타났다(p<0.01). 잡종 3배체는 두고/두장, 등지느러미 기부장/체장 및 가슴지느러미 길이/체장의 계측형질에서는 친어로 사용된 무지개송어와 산천어의 중간을 나타낸 반면 상악장/두장의 계측형질에서는 무지개송어 쪽을 다소 닮게 나타났다. 이러한 결과들은 잡종 3배체에서 3배체화에 따른 사용된 친어들에 대비된 성비 그리고 계측형질에서의 특징을 나타내었다.

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한국인 두경부 편평세포암 환자에서 Glutathione S-transferase(GST)M1, GSTT1 및 GSTP1유전자 다형성 및 유전적 감수성 (Polymorphism of Glutathione S-Transferase(GST)M1, GSTT1, GSTP1 and Genetic Susceptibility to Head and Neck Squamous Cell Carcinoma in Korean Population)

  • 태경;서인석;강미정;조석현;김경래;이형석
    • 대한두경부종양학회지
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    • 제18권2호
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    • pp.150-156
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    • 2002
  • Objectives: Most of human cancers may result from exposure to environmental carcinogens, and individual effectiveness in the detoxification of these chemicals will influence susceptibility to malignant disease. Glutathione S-Transferases(GSTs) enzymes are involved in the detoxification of active metabolites of many carcinogens from tobacco smoke and may be important in modulating susceptibility to smoke-related cancer. The purpose of this study is to determine the polymorphism of GSTM1, GSTT1, and GSTP1 in control group and head and neck squamous cell carcinoma group of Korean, and to investigate the effect of GSTs polymorphism on the risk of head and neck cancer. Materials and Methods: A hospital-based case-control study was performed with a group of 133 control individual and 136 head and neck squamous cell carcinoma patients. The polymorphisms of GSTs were analysed using polymerase chain reaction in GSTM1 and GSTTl, and polymerase chain reaction-restriction fragment length polymorphism in GSTP1. Results: The relative risk (odds ratio) of GSTM(-) genotype was 1.14(95% CI, 0.70-1.85) compared to GSTM1(+). The odds ratio of GSTTl(-) genotype was 0.91(95% CI, 0.55-1.50). In old age($65$) group, the odds ratio of GSTT1(-) genotype was 5.2(95% CI, 1.53-17.89). The GSTP1 Val/Val genotype conferred a 1.7-fold risk(95% CI, 0.40-7.34) of head and neck cancer compared with GSTP1 Ile/Ile genotype. Among the combined genotypes of GSTs, GSTM1(-)/GSTT1(+)/GSTP1 Val/Val and GSTM1(-)/GSTTl(-)/GSTP1 Ile/Val genotypes conferred a 2.6-fold and 1.3-fold risk(95% CI, 0.24-14.15 and 0.43-3.14) compared with the GSTM1(+)/GSTTl(+)/GSTP1 Ile/Ile genotype, respectively. Conclusion: Polymorphism of GSTs might modulate susceptibility to head and neck cancer in Korean population. The genotype of GSTP1 Val/Val and combined genotypes of GSTM1(-)/GSTT1(+)/GSTP1 Val/Val, and GSTM1(-)/GSTT1(-)/GSTP1 Ile/Val might be important risk factors to determine the individual susceptibility to head and neck squamous cell carcinoma.

Photodimerization of 5,7-Dimethoxycoumarin

  • Shim, Sang Chul;Jeong, Bong Mo;Paik Young Hee
    • Bulletin of the Korean Chemical Society
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    • 제13권6호
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    • pp.684-688
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    • 1992
  • Three photocyclodimers of 5,7-dimethoxycoumarin (DMC) were isolated and characterized from the photolysis of DMC in acetonitrile. The configuration of the dimers was found to be anti head-to-head, syn head-to-head and syn head-to-tail, respectively. The number and the ratio of the products are solvent dependent. The anti head-to-head dimer is favored in nonpolar solvents and the preference decreases as the solvent polarity increases giving almost 100${\%}$ syn dimers and less than 1${\%}$ anti dimer from methanol solution. The overall yields of dimers also increase with the solvent polarity. From sensitization and quenching experiments, anti dimer was found to be formed via excited singlet state while syn dimers were formed via both excited singlet and triplet states.

노인에서 머리회전을 동반한 보행이 보행변수에 미치는 영향 (Effects of the Head-Turn Gait on Gait Parameters in the Elderly)

  • 이명희;장종성
    • PNF and Movement
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    • 제19권3호
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    • pp.435-440
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    • 2021
  • Purpose: The purpose of this study is to investigate the effects of older adult's head-turn gait on gait parameters by comparing with head oriented forward gait and to provide criteria for their risk of falling compared to young adult. Methods: The subjects were 19 young adults in their 20s and 18 older adults in their 60s or above residing in Daegu or Gyeongsangbuk-do. To evaluate their gait parameters, spatiotemporal gait parameters were measured using a gait analysis tool (Legsys, BioSensics, USA) under two conditions: 1) walking while keeping one's eyes forward and 2) walking while turning the head. The measurement for each test was performed after one practice session, and the mean value of three measurements was analyzed. The collected data were statistically processed using a two-way analysis of variance (ANOVA) to compare any differences in gait parameters between the two groups under the two conditions. The statistical significance level was set at α=0.05. Results: According to the comparison of gait parameters in young adult and older adult between the head oriented forward gait and head-turn gait, statistically significant differences were observed in two parameters: stride length according to the height ratio and stride speed obtained by dividing the stride length according to the height ratio by time (p<0.05). Conclusion: The results of this study indicate that the head-turn gait causes greater differences in stride length and speed among older adult than in young adult and therefore can act as a cause of falling.

소득계층별 한국 차입 가계의 부실화 가능성 연구 (The study on insolvency prediction for Korean households across income levels)

  • 이종희
    • 가족자원경영과 정책
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    • 제22권1호
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    • pp.63-78
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    • 2018
  • This study examined the insolvency of debtors using multiple-indicator approaches and compared the outcomes across income levels with the 2016 'Household Financial and Welfare Survey'. This study used (1) the total debt to total assets ratio (DTA), (2) the total debt service ratio (DSR), and (3) the Household Default Risk Index (HDRI) recently developed by the Bank of Korea. Households in the lowest income quintile were more likely to be insolvent than any other income group. Demographics, such as age and gender of the household head, and most of the financial variables significantly increased the likelihood of insolvency based on the DTA. The number of household members and job status increased the likelihood of insolvency based on the DSR. Also, age, gender of the household head, and most of the financial variables increased the likelihood of household insolvency based on the HDRI after controlling for other demographics and financial variables.

재무비율로 평가한 농촌 중ㆍ노년기 가계의 재정상태에 영향을 미치는 요인 분석 (Factors Affecting Financial Status of the Rural Middle-aged and Old-aged Households)

  • 최윤지;최현자
    • 한국농촌생활과학회지
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    • 제9권1호
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    • pp.43-54
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    • 1998
  • This study attempted to investigate the factors affecting financial status of the rural middle-aged and old-aged household. The results shelved that the significant variables which influenced on the probability of financial security measured by consumption to income ratio were sex and education level of the household head, family size, total income, total expenditure and total assets. The most influential variables on the probability of financial security measured by liquidity ratio was liquid assets, and total assets. Education level of the household head. liquid assets, total assets, and total debt had significant effects on the probability of financial security estimated by debt burden ratio. Among the economic variables, only liquid asset had significant negative effects on the probability of financial security assessed by the capital stock ratio.

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