• 대한후두음성언어의학회지
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• 제25권1호
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• pp.36-38
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• 2014

The patient suffered cardiac arrest 8 months before presentation. She has been suffering hoarseness and exertional dyspnea and nocturnal stridor. Upon flexible laryngoscopy, her vocal cords showed no motion and fixed in paramedian position. There was no causal finding on neck CT. EMG showed some muscular activity. Under the suspicion of crico arytenoid fixation, we performed suspension laryngoscopy, and found the arytenoid cartilage was fixed with short and stout scar, which was removed with scissors. Just after surgery she regained her voice and respiration.

• Radiation Oncology Journal
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• 제29권4호
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• pp.243-251
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• 2011

Purpose: To evaluate the prognostic value of metabolic tumor volume (MTV) and maximum standardized uptake value (SUVmax) on initial positron emission tomography-computed tomography (PET-CT) and investigate the clinical value of SUVmax for early detection of locoregional recurrent disease after postoperative radiotherapy in patients with locally advanced head and neck squamous cell carcinoma (HNSCC). Materials and Methods: A total of 100 patients with locally advanced HNSCC received primary tumor excision and neck dissection followed by adjuvant radiotherapy with or without chemotherapy. The MTV and SUVmax were measured from primary sites and neck nodes. The prognostic value of MTV and SUVmax were assessed using initial staging PET/CT (study A). Follow-up PET/CT scan available after postoperative concurrent chemoradiotherapy or radiotherapy were evaluated for the SUVmax value and correlated with locoregional recurrence (study B). A receiver operating characteristic (ROC) curve analysis was used to define a threshold value of SUVmax with the highest accuracy for recurrent disease assessment. Results: High MTV (>41 mL) is negative prognostic factor for disease free survival (p = 0.041). Postradiation SUVmax was significantly correlated with locoregional recurrence (hazard ratio, 1.812; 95% confidence interval, 1.361 to 2.413; P < 0.001). A cutoff value of 5.38 from follow-up PET/CT was identified as having maximal accuracy for detecting locoregional recurrence by ROC analysis. Conclusion: MTV at staging work-up was significantly associated with disease free survival. The SUVmax value from follow-up PET/CT showed high diagnostic accuracy for the detection of locoregional recurrence in postoperatively irradiated HNSCC.

• 대한두경부종양학회지
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• 제20권1호
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• pp.44-48
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• 2004

Primary malignancies of hard palate are rare, espicially adenocarcinoma of minor salivary gland in hard palate. The clinical stage of the tumor and its histologic grade at the time of treatment were significant predictors of survival. A 33-year-old woman was diagnosed with stage II, polymorphous low-grade adenocarcinoma of the hard palate and treated with surgery. We thougt that she would have excellent prognosis. After that, there was no definite evidence of recurrence during 3 months. Since then, the patient herself decided to discontunue follow-up. 9 years after that she came to the hospital due to both submandibular mass without any sign of local recurrence. CT scan and biopsy of the mass revealed multiple cervical metastatic adenocarcinoma without distant metastasis and the histologic findings were similar to that of the primary hard palate adenocarcinoma. So, we present this case with the review of literature.

• 대한두경부종양학회지
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• 제36권1호
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• pp.27-31
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• 2020

The midline nasal dermoid cysts are rare congenital neoplasms, which are diagnosed frequently in childhood. Masses are often noticeable at birth gaining size over time with recurrent infections and usually arise from the nasal cavity or lower 1/3 of the nasal dorsum. CT scan as the primary investigation is helpful to determine accurately the size and extent of the lesion as well as the integrity of adjacent bony structures. MRI scan is recommended to rule out an intracranial extension or sinus tracts. Treatment of choice is the complete surgical excision preserving the cyst wall. Here in, we present an unusual case of nasofrontal dermoid cyst in a 19-year-old boy without radiographic evidence of transcranial extension. In this case, we surgically removed nasofrontal dermoid cyst via transcolumellar approach. We also corrected saddle nose deformity after mass removal. Therefore, in this case, we experienced a successful case in which the nasofrontal dermoid cyst was totally removed without facial scar and deformity.

• 임상이비인후과
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• 제29권2호
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• pp.182-189
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• 2018

Background and Objectives : There were few literatures about the relationship between upper airway disorders and cardiovascular risk factors such as hypertension, although an association between impaired lower respiratory function and cardiovascular alterations was often reported. Our purpose was to assess the relationships between chronic sinusitis and hypertension. Materials and Methods : Three hundred subjects with bilateral chronic sinusitis who underwent functional endoscopic sinus surgery between 2015and 2017 were evaluated. Six hundred forty subjects without any nasal diseases were enrolled as a control group. Blood pressure and body mass index (BMI) were measured using a standardized method, and subjects were asked about current use of any antihypertensive medication, history of diabetes, smoking and alcohol drinking habits.Sinusitis group was assessed by nasal endoscopic examination, paranasal sinus CT scan and allergy test. Results : Average systolic and diastolic blood pressures were statistically significantly higher in subjects with sinusitis than control group. Chronic rhinosinusitis was associated with a 1.415-fold (95% confidence interval 1.053-1.930) increased hazard of hypertension after multivariate adjustment. Conclusions : These results suggest that sinusitis is associated with high blood pressure. Therefore patients with sinusitis may need special attention for blood pressure control. Further studies need to be performed to elucidate the pathogenesis behind such associations.

• 대한두경부종양학회지
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• 제17권1호
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• pp.38-41
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• 2001

Background and Objectives: Thyroid nodules can be diagnosed by FNAB, neck sonography, CT scan, or frozen section with relative accuracy. But some cases, which show no malignancy with those methods, are proved differentiated carcinomas on permanent sections. These false negative results of those diagnostic methods pose difficulties in the surgeon's decision-making process. We analyzed completion thyroidectomies retrospectively in order to make a treatment guideline for thyroid nodules. Materials and Methods: During the last six years, we performed 243 thyroid lobectomies, no evidence of malignancy with preoperative or intraoperative diagnostic methods at the Department of Otolaryngology-Head and Neck Surgery, Ansan and Anam Korea University Hospital. Among these cases, 23 patients (male 6, female 17, mean age 33.4 year old) were proved differentiated thyroid carcinomas on permanent section and we performed completion thyroidectomies. Results: Preoperative FNAB showed seven cases of nodular hyperplasia, 11 cases of follicular adenoma, and five cases of inadequate specimen. Among total 15 cases on frozen section, five cases were nodular hyperplasias, and 10 cases were follicular adenomas. Pathologic results of the permanent section were six cases of papillary cell carcinoma and 17 cases of follicular cell carcinoma. Completion thyroidectomy was performed on all these cases. Conclusion: FNAB and frozen section cannot be sufficient to make the diagnosis of thyroid nodule, we consider that completion thyroidectomy should be performed at the moment with malignant evidence on permanent section.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2003년도 제27회 추계학술대회
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• pp.77-77
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• 2003

CT와 MRI의 단면 영상을 대상으로 영상분할 (Image segmentation)과 Image registration방법을 이용하여 인체 모델을 개발 하고자 한다. 우선 인체의 Head와 Neck부분의 CT와 MR 영상을 얻어 뼈, 근육, 인대, 그리고 그 밖의 장기의 해부학적 영상 특징을 분석하였다. 인체의 Head와 Neck 부분에 대한 CT와 MR 영상에 대해 각 부위별로 ROI(region-of-interrest)를 설정하였고, 각 volxel 마다 3차원 좌표를 계산할 수 있는 소프트웨어를 개발하였다. 특히 각 해부학적 영상에서 부위별로 CT 번호를 분석하고, pulse sequence에 따른 MRI 영상의 부위별 특정을 분석하였다. 이 분석한 자료를 바탕으로 영상 분할을 하였다. 영상 분할전에 각종 잡음(noise) 제거 및 영상 분할을 효과적으로 처리하기 위해 기본적인 영상처리 (filtering)를 구현하였고, 대조도(contrast) 및 밝기(brightness)를 조절할 수 있게 프로그램을 구현하였다. 영상 분할 방법 중 선(line) 및 에지(edge) 의 검출 방법, 문턱치화(threshold) 방법, 영역확대(region growing) 방법으로 영상 분할을 해봄으로써 우리의 인체 모델링 개발에 가장 적합한 영상 분할 알고리듬 방법을 찾도록 시도하였다. 결과적으로 말하면, 한가지 방법의 알고리듬을 쓰는 것보다는 인체의 부위에 따라 두 가지 이상의 알고리듬 방법을 쓰는 것이 원하고자 하는 부위를 영상 분할하는데 더 효과적이다는 것을 알게 되었다. 우리의 연구 과제에서는 영역확대(region growing) 방법과 문턱치화 방법, 모드법(피크니스, 밸리)의 알고리듬을 이용하여 영상 분할을 한 결과 우리가 얻고자 하는 인체 부위별 중 근육과 뼈를 구별하는데는 별 무리가 없었으나, 인대 및 기타 장기를 구별하는데는 어려움을 겪게 되었다. 이후에 좀더 알고리듬을 연구하여 이번 연구에서 구별하기 어려운 장기 부분도 구별 할 수 있도록 노력하겠다.

• 대한약침학회지
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• 제10권2호통권23호
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• pp.99-105
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• 2007

Objectives : It is the aim of this study to derive lurker studies evaluating the effectiveness of bee-venom phamacopuncture on malignant melanoma patients. We present a patient of malignant melanoma at right maxilla who survives over one year with stable disease (SD) by the treatment of Bee Venom Phamacopuncture (BVP). Methods : We followed the treatment and examination. We prescribed to the patient what to be taken 1.5cc BVP once a day. Picture series, Head series were followed-up and Neck computed tomography (CT) and positron emission tomography computed tomography (PET CT) were performed to evaluate the therapeutic efficacy. Results : The patient survives over one year and continued stable disease over 6 months. Picture series, Head series X-ray, neck CT and PET CT were shown no interval change. Conclusion : This case may give us the possibility that BVP offers potential benefits for patients with malignant melanoma.

• Journal of International Society for Simulation Surgery
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• 제2권2호
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• pp.67-70
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• 2015

We propose an automatic vessel segmentation method of vertebral arteries in CT angiography using combined circular and cylindrical model fitting. First, to generate multi-segmented volumes, whole volume is automatically divided into four segments by anatomical properties of bone structures along z-axis of head and neck. To define an optimal volume circumscribing vertebral arteries, anterior-posterior bounding and side boundaries are defined as initial extracted vessel region. Second, the initial vessel candidates are tracked using circular model fitting. Since boundaries of the vertebral arteries are ambiguous in case the arteries pass through the transverse foramen in the cervical vertebra, the circle model is extended along z-axis to cylinder model for considering additional vessel information of neighboring slices. Finally, the boundaries of the vertebral arteries are detected using graph-cut optimization. From the experiments, the proposed method provides accurate results without bone artifacts and eroded vessels in the cervical vertebra.

• 대한기관식도과학회지
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• 제15권1호
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• pp.64-67
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• 2009

Paratracheal air cysts are rare lesions and detected incidentally during CT scan or autopsy. Histopathologic diagnoses of paratracheal air cysts include trachocele, tracheal diverticulum and lymphoepithelial cyst. The cysts are lined by ciliated columnar epithelium and have communication with trachea. Previous reports suggested an association with obstructive lung disease because of increased expiratory pressures in these patients. Most of these cysts are asymptomatic but rarely cause productive cough, wheezing, recurrent laryngeal nerve paralysis and difficult intubation. We report a case of paratracheal air cyst causing dyspnea with a review of literature.