• Title/Summary/Keyword: HeLa cell line

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Physiological Activity of Astaxanthin and its Inclusion Complex with Cyclodextrin (Astaxanthin과 Astaxanthin-Cyclodextrin 포접화합물의 생리활성)

  • Kim, So-Young;Cho, Eun-Ah;Yoo, Gui-Jae;Yoo, Ji-Min;Son, Seok-Min;In, Man-Jin;Kim, Dong-Chung;Chae, Hee-Jeong
    • KSBB Journal
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    • v.24 no.6
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    • pp.570-578
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    • 2009
  • In vitro biological activities such as antioxidant, whitening, anti-hangover and anticancer activities were evaluated. The antioxidant activities of astaxanthin and H. pluvialis extract were significantly higher than that of $\alpha$-tocopherol when the antioxidant activities were determined as xanthine oxidase inhibition, hydroxyl radical scavenging and DPPH radical scavenging. The whitening effect of H. pluvialis extract was about two times as kojic acid. H. pluvialis extract indicated an anticancer activity on a cervical cancer cell line. Astaxanthin showed anti-hangover effect of 1.5 times as jiguja extract. The anti-hangover effect of the inclusion complex (As-$\beta$-CD) was about 1.2 times of jiguja extract. And, the inclusion complex of Haematococcus pluvialis (H.p.-$\beta$-CD) showed almost the same whitening effect as kojic acid.

Phytochemical Constituents and Anticancer Activity of Sphagnum palustre Extract (물이끼 추출물의 식물화학적 성분 및 항암활성 연구)

  • Nam, Jung-Hwan;Jeong, Jin-Cheol;Yoon, Young-Ho;Hong, Su-Young;Kim, Su-Jeong;Jin, Yong-Ik;Lee, Ye-Jin;Yoo, Dong-Lim;Lee, Kyung-Tae;Park, Hee-Juhn
    • Korean Journal of Plant Resources
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    • v.24 no.1
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    • pp.40-47
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    • 2011
  • Sphagnum palustre is a semi aquatic moss. S. palustre has been used as Korean traditional medicine to treat cardiac pain and stroke. This study was carried out to analyze phytochemical constituents of S. palustre and investigate the biological activity for the promotion of human health. At first, we isolated seven compounds from the ethanolic extract of this plant, and their structures were characterized by spectroscopic methods. Their structures were characterized to be Coumarin(1), Caffeic acid(2), Quercetin(3), Astragalin(4), Luteolin(5), Chlorogenic acid(6), Rutin(7) were for the first time reported from this source. The ethanol extract from S. palustre which was tested for its anticancer activity against three human tumor cell line by in vitro assay.