• 한국환경과학회지
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• 제15권11호
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• pp.1011-1016
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• 2006

Recently, volatile organic compound(VOC) has been noted as a main cause of air pollution. VOC, with its toxic and offensive odor, is hazardous to health. Furthermore indoor, underground and hish-rise buildings are preferable living spaces. People spend more than 80% of the day indoor, so indoor air pollution is a matter of importance. In Korea, from 2004, 10 types of indoor pollutants in public facilities have been identified. However, there is no standard for individual VOC, so the regulation has not yet effectively been carried out. In this study, we have studied on the diffusion of Benzene in a room using a numerical analysis for various air-controlled conditions consisted of door, window and ventilation system. This study investigates spatial concentration distribution and time-history of room-averaged benzene concentration for several cases. The results of this study show that when the room is ventilated by a small fan only for 30 minutes, the average concentration of benzene is decreased a very little, thus the impact to human body would be serious compared to the case of natural ventilation by window and door, In the case of natural ventilation by window and door, if the wind speed is higher than 0.5m/s, it takes small than 4 minutes for benzene to spread to the target concentration of $1.2mg/m^3$.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5727-5731
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• 2015

Background: There is a long standing interest in natural compounds especially those with a high polyphenolic content and high scavenging activity for hazardous free radicals. Cornus mas (CM) fruit is well known for its antioxidant activities; however, its toxicity against human cancers needs to be addressed. Here, we investigated selective anticancer effects of CM on different human cancer cells. Materials and Methods: A hydro-alcoholic extract of CM (HECM) was prepared and total phenolic content (TPC) and total flavonoid content (TFC) were determined by colorimetric assays. Antioxidant activity was assessed with respectto DPPH radical scavenging. MTT assays were used to evaluate the cytotoxicity of different doses of CM (0, 5, 20, 100, 250, 500, $1000{\mu}g/ml$) towards A549 (lung non small cell cancer), MCF-7 (breast adenocarcinoma), SKOV3 (ovarian cancer) and PC-3 (prostate adenocarcinoma) cells. Results: Significant (P<0.05) or very significant (P<0.001) differences were observed in comparison to negative controls at all tested doses ($5-1000{\mu}g/ml$). In all cancer cells, HECM reduced the cell viability to values below 26%, even at the lowest doses. In all cases, $IC_{50}$ was obtained at doses below $5{\mu}g/ml$. The mean growth inhibition was 81.8%, 81.9%, 81.6% and 79.3% in SKOV3, MCF-7, PC-3 and A549 cells, respectively. Conclusions: Altogether, to our best knowledge, this is a first study that evaluated toxicity of a HECM with high antioxidant activity in different human cancer cells in vitro. Our results indicated that a hydro-alcoholic extract of CM possesses high potency to inhibit proliferation of different tumor cells in a dose independent manner, suggesting that an optimal biological dose is more important and relevant than a maximally tolerated one.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10603-10605
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• 2015

Background: The Prostate cancer is the 2nd most common cancer worldwide for males, and the 5th most common cancer overall, with an estimated 900,000 new cases diagnosed in 2008 (14% of the total in males and 7% of the total overall) aim of this study was to assess some of the most proposed environmental factors influencing the incidence of prostate cancer among Iranian men. Smoking, opioids, occupation and living location were considered as studied risk factors of the prostate cancer in this research. Material and methods: Two groups of affected men with prostate cancer and controls aged 50-75 years referred to medical clinics were subjects in this case-control study. Living and working place, smoking and drug consuming habits were assessed for any associations with prostate cancer. Results: The largest number, of patients, in order, belonged to Tehran, provincial capitals, major industrial cities, small towns and villages, respectively. The disease showed links with smoking and drugs with a significant difference between controls and patients (P value <0.0001). Conclusions: Our recent evidence duplicates previously done researches confirming the serious adverse effects of smoking and drugs on the prostate cancer occurrence in Iranian men. Living place bearings some hazardous behaviors which increases the rate of diseases as well as advanced chance for associated cancers like prostate.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2003년도 International Symposium
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• pp.70-86
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• 2003

Despite its usability, TCE has been managed as a hazardous material due to the toxicity and many contamination cases were surveyed in some developed countries. U.S.EPA(Kram et al., 2001) suggested DNAPL characterization methods and approaches based on survey experiences at several sites. However, Korea has not the least assessment of contamination and trial of remediation, although there are a lot of doubtable areas where ground water would be contaminated with TCE. In this study, we try to assess the volume and extent of ground water contamination with TCE and delineate the contamination source zones in an industrial area. Ground water in this area flows through fractures and the contaminant TCE has the properties of high volatility, high density and low partitioning to soil material. Thus, we applied a variety of technical approaches to identify the contamination status; documentary, hydrogeochemical, hydrogeological and geological surveys. In addition, additional survey was performed based on the interim findings, which showed that ground water contamination was limited to the relatively small area with high concentrations to the deep place. The contamination source zone is estimated to be the asphalt test institute where a great deal of TCE has been used to analyze the amount of asphalt soluble in TCE since 1984. Based on the contamination characterization and a myriad of documents about ground water remediation, appropriate site remediation management options will be recommended later. This study is now under way and this paper was focused on describing the technical approaches used to achieve the goals of this study.

• 한국지하수토양환경학회지:지하수토양환경
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• 제8권2호
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• pp.44-54
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• 2003

토양 슬러리 시스템에서 유해물질의 미생물 분해시 계면활성제를 고려한 속도론적 모델을 개발하였다. 이 모델은 오염물질과 계면활성제의 분배, 미생물의 수용액상, 미셀상, 흡착상 분해, 계면활성제 첨가에 의한 대상물질 용해, 대상물질의 물질전달을 포함한다. 오염물질은 phenanthrene, 계면활성제는 Triton X-100, Triton NP-10, Igepal CA-720, Brij 30을 적용하였다. 미셀상 분해가 존재할 경우 매우 낮은 미셀상 이용도에서도 전체 분해속도를 크게 향상시킬 수 있었다. 미셀상 이용성이 존재하는 경우와 그렇지 않은 경우 모두 계면활성제 농도가 증가할수록 수용액상 농도가 감소하여 전체 분해속도는 감소하였다. 흡착상 분해는 수용액상 분해나 미셀상 분해와 비교하여 전체 분해속도에 미치는 영향이 적었다. 본 모델은 계면활성제를 이용한 오염토양 생물복원시 계면활성제 탐색과 최적 공정 설계에 활용될 수 있을 것이다.

• 한국안전학회지
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• 제29권4호
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• pp.147-152
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• 2014

The purpose of this study, the overall occupational safety and health status and identify the characteristics of the workers engaged in the field of quick services, substitute driving services, home delivery, caregiver, film and television arts, to take appropriate measures to prevent industrial accidents, profession and working environment, safety recognition and education, and safety activities, accident experience and job stress survey. Survey using a structured questionnaire, 846 people directly interview research. Safety consciousness level of himself or herself was "fair level" of 3.19 points and those of colleagues and the general public were evaluated to be low as 2.84 points and 2.54 points, respectively. During the last 12 months, 21.3% of total workers in 5 job categories have received an industrial safety health education for job-related accident or disease and 87.6% of workers engaged in caregiver have received an industrial safety health education for job-related accident or disease. The proportions for delivery worker, substitute driving service and quick service/cultural art were 26.4%, 12.1% and below 10%, respectively. Frequency of having received an education was 5.7 days on average and education hour was 9.2. Regarding cases of having experienced job-related accident or having been exposed to job-related disease over the past 1 year, 17.0% of total respondents have experienced accident and 21.3% have experienced job-related disease. Preventive education for occupational safety is required to be expanded and strengthened. Except caregiver, the proportion of having received an information and education for safety rules and hazardous factors. Safety education is urgently required in order to prevent and reduce accident. Safety and health guideline is required to be developed and disseminated in order to prevent accident in advance.

• 한국안전학회지
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• 제15권3호
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• pp.115-123
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• 2000

공압구동기는 다양한 형태의 위험작업 환경하에서 사용되고 있다. 또한, 공압구동기를 적용한 공정은 일반적으로 환경친화적인 것으로 인식되고 있다. 대부분의 경우, 공압구동기는 point to point 제어에 사용된다. 그러나, 최근 공압구동기의 정밀 위치제어에 관한 많은 연구가 수행되고 있다. 본 연구에서는 비례밸브로 구성된 공압구동기의 추종위치제어에 관하여 논의한다. 제안되는 제어기는 압력제어 루프와 위치제어 루프로 구성된다. 공기의 압축성에 기인한 비선형성을 상쇄하기 위하여 되먹임선형화에 의한 PID제어기가 압력제어 루프에 사용된다. 위치제어에는 신경회로망을 사용하여 비선형성을 보상한 PID제어기가 사용된다. 실험결과에 의하면, 제안된 제어기는 공압구동기의 추종성능을 대폭 향상시킬 수 있는 것으로 나타났다.

• 한국산업보건학회지
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• 제28권1호
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• pp.91-99
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• 2018

Objectives: From a policy perspective, the introduction of confidential information reviews is a vital task for expanding workers' right to know and improving hazardous materials information communication. In this study, rational methods for introducing and administering confidential information reviews were examined as a part of advancing chemical information communication. Methods: The domestic status, social demands, and control cases from other countries about confidential information in material safety data sheets(MSDSs) were all examined. Additionally, principles for introducing MSDS confidential information review, what needs to be revised prior to its introduction, and procedures and manners of reviewing confidential information were suggested. Results and Conclusions: When composition information on MSDS needs to be protected in the EU and Canada, confidential information should be claimed and then approved by competent authorities with a principle of reviewing confidential information prior to rescinding information from MSDS. Applying the same principle, certain information on an MSDS that needs to be protected should be reviewed and approved in Korea. As a result, the MSDS is communicated with approval numbers replacing composition information. MSDS confidential information review has five steps, including deciding whether chemicals claimed to be confidential are excluded from applying for a confidentiality exemption, the names and concentration ranges of ingredients are adequate, and the claimed information is valid in terms of confidentiality.

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2009년도 춘계학술논문발표회 논문집
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• pp.82-92
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• 2009

본 연구에서는 군부대 위험물안전관리 실무자를 대상으로 군부대 위험물 운영 실태와 군부대 위험물 안전사고 사례 분석을 통해, 위험물 관련 취급소의 안전관리 실태, 안전관리 계획, 안전관리 교육내용, 안전관리자 교육등에 관한 의식 등을 설문조사를 통해 분석코자 하였다. 또한 이러한 연구를 바탕으로 현행 군부대 위험물의 실태를 조사하고, 향후 특수집단인 군부대위험물의 안전관리를 함에 있어 군의 특수성에 적합한 체계적인 안전관리 계획을 수립함은 물론 안전교육 프로그램을 개발하여 군관계자들의 관심도 고취 및 위험물 작업장의 효과적인 안전관리를 통해 군부대에서의 위험물 안전사고요인을 사전에 차단함으로서 위험물 안전관리자 및 관계인으로 하여금 안전사고의 위험요소에 대해 인지할 수 있도록 홍보 및 교육활성화 방안을 마련하고자 하였다.

• 한국학교보건학회지
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• 제33권3호
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• pp.194-202
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• 2020

Purpose: The purpose of the study was to develop educational materials on field practice safety based on existing field practice data and accident cases regarding vocational high schools and apply them to identify their impact. Methods: The existing data, accumulated since 2010, on field practices of vocational high schools were analyzed, and educational materials regarding field practices were developed by six experts. 195 students in three vocational high schools were surveyed before and after being taught with the materials. The survey asked about their knowledge of industrial safety and health and attitudes toward industrial safety and health. Results: As a result of the study, harmful environments for field practices of vocational high schools were physical, chemical, ergonomic, and emotional labor, and the consequences were accidents, death by overwork, musculoskeletal diseases, etc. The materials covered students' rights and how to respond to workplace accidents in the 1st round, how to organize a workshop in the 2nd round, workplace safety and health signs in the 3rd round, prevention of musculoskeletal diseases in the 4th round, management of physical risk factors in 5th round, management of hazardous chemicals in 6th round, wearing and managing protective equipment in 7th round, first aid depending on the situation in the 8th round, CPR and defibrillator in the 9th round, sexual harassment in the 10th round, and prevention of sexual violence in the 11th round. After completing the education, their knowledge of industrial safety and health increased significantly from 6.52 points to 7.01 points. Conclusion: The results of this study suggest: first, to statistically organize the data on accidents that have occurred during field practices of vocational high schools; second, to develop a systematic curriculum for high school 1st to 3rd graders on accidents that may happen during field practices of vocational high schools.