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Effect of Dietary Selenium on $\delta$-Aminolevulinic Acid Dehydratase Activity in Lead Poisoned Rats (식품 Selenium이 납중독된 흰쥐에 있어서 $\delta$-Aminolevulinic Acid Dehydratase 활성에 미치는 영향)

  • 방진숙
    • Journal of Nutrition and Health
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    • v.24 no.6
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    • pp.526-533
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    • 1991
  • The effect of dietary selenium on the activity of $\delta$-aminolevulinic acid dehydratase (ALAD) inhibited by the administration of lead were investigated in rats. The levels of dietary lead in the acetate form were 0(contro)200, 1, 000, 2, 000 and 5, 000ppm. Except control group four-level of lead diet groups were again subdivided into two depending on with and without 0.5ppm selenium supplementation. Sixty-three 40-day-old male Sprague-Dawley rats weighing 141$\pm$5g were distributed into total of nine diet groups according to RCB design and fed ad libidum for 4 weeks. Lead dietary groups did not show any significnat difference in food intake from the control group. Food efficiency and weight gain were lower in 2.000ppm and 5, 000ppm lead groups but not found in selenium supplemented ones. Hemoglobin contents hematocrit values ALAD activities in blood were significantly decreased and urinary aminolevulinic acid(ALA) excretion increa-sed with increasing dietary lead levels but partly restored by selenium supplementation. however only in 200, 1, 000 and 2, 000ppm dietary lead groups. On the other hand the hepatic ALAD activites of all four lead groups were recovered 19-30% from suppression by selenium supplementation. It was concluded that selenium administration alleviated lead toxicity in rats.

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Statistical analysis of hazen-williams C and influencing factors in multi-regional water supply system (광역상수도 유속계수와 영향인자에 관한 통계적 분석)

  • Kim, Bumjun;Kim, Gilho;Kim, Hung soo
    • Journal of Korea Water Resources Association
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    • v.49 no.5
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    • pp.399-410
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    • 2016
  • In case of the application of Hazen-Williams C for design, operation or maintenance of water supply system, field situations always should be reflected on the factors. In this study, the relationships between C factors and influencing factors are analyzed using statistical techniques with 174 measured C factor data collected in periodic inspection for safety diagnosis in multi-regional water supply systems. To analyze their relationships, cross analysis, one-way ANOVA, correlation analysis were conducted. Analysis results showed that C factors had high correlations with both of elapsed year and pipe diameter and were relatively highly affected by coating material among influencing factors with the categorical type. On the other hand, elapsed year, pipe diameter and water type were meaningful influencing factors according to the results of multiple regression analysis. The Cluster analysis revealed that C factors had a tendency of being fundamentally classified on the basis of the elapsed year of about 20 years and the pipe diameter of 1500mm. Although C factors were generally greatly affected by elapsed year, size of pipe diameter relatively had an large influence on values of them in case of large diameter pipes. Lastly, It can be suggested that C factor estimation formulas using multiple regression analysis and clustering analysis in this study, can be applied as decision standards of C factor in multi-regional water supply systems.

Effect of Sc Addition on Microstructure, Electrical Conductivity, Thermal Conductivity and Mechanical Properties of Al-2Zn-1Cu-0.3Mg Based Alloy (Al-2Zn-1Cu-0.3Mg합금의 Sc첨가에 따른 미세조직, 전기전도도, 열전도도 및 기계적 특성 변화)

  • Na, Sang-Su;Kim, Yong-Ho;Son, Hyeon-Taek;Lee, Seong-Hee
    • Korean Journal of Materials Research
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    • v.30 no.10
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    • pp.542-549
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    • 2020
  • Effects of Sc addition on microstructure, electrical conductivity, thermal conductivity and mechanical properties of the as-cast and as-extruded Al-2Zn-1Cu-0.3Mg-xSc (x = 0, 0.25, 0.5 wt%) alloys are investigated. The average grain size of the as-cast Al-2Zn-1Cu-0.3Mg alloy is 2,334 ㎛; however, this value drops to 914 and 529 ㎛ with addition of Sc element at 0.25 wt% and 0.5 wt%, respectively. This grain refinement is due to primary Al3Sc phase forming during solidification. The as-extruded Al-2Zn-1Cu-0.3Mg alloy has a recrystallization structure consisting of almost equiaxed grains. However, the as-extruded Sc-containing alloys consist of grains that are extremely elongated in the extrusion direction. In addition, it is found that the proportion of low-angle grain boundaries below 15 degree is dominant. This is because the addition of Sc results in the formation of coherent and nano-scale Al3Sc phases during hot extrusion, inhibiting the process of recrystallization and improving the strength by pinning of dislocations and the formation of subgrain boundaries. The maximum values of the yield and tensile strength are 126 MPa and 215 MPa for the as-extruded Al-2Zn-1Cu-0.3Mg-0.25Sc alloy, respectively. The increase in strength is probably due to the existence of nano-scale Al3Sc precipitates and dense Al2Cu phases. Thermal conductivity of the as-cast Al-2Zn-1Cu-0.3Mg-xSc alloy is reduced to 204, 187 and 183 W/MK by additions of elemental Sc of 0, 0.25 and 0.5 wt%, respectively. On the other hand, the thermal conductivity of the as-extruded Al-2Zn-1Cu-0.3Mg-xSc alloy is about 200 W/Mk regardless of the content of Sc. This is because of the formation of coherent Al3Sc phase, which decreases Sc content and causes extremely high electrical resistivity.

Moisture Sorption and Cooking Properties of Soybeans (콩의 흡습 및 조리성질)

  • Suh, Chung-Sik;Lee, Ae-Rang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.4
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    • pp.398-402
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    • 1989
  • Moisture sorption and cooking properties of two varieties of Korean soybean(Jangyup and Whangkeum) were studied. When soybean was stored under the various relative humidities (RH) of 33-86% at 16'E for 125hours, its sorption behaviors were divided into two : desorption at the RHs of 33 and 44% and adsorption at the RHs of above 55%. The sorption rate was decreased rapidly during storage. In comparisons with only storage humidities, the sample stored at higher RH held the higher sorption rate. The relationships between storage time and sorption rate were applied well to the equation, log dw/dt= b log t+ log a, where w is the moisture content(%, db), t is time(hour) and a and b are the parameters which were calculated from the experimental data. The calculated moisture contents from the equation agreed well with the measured moisture contents. On the other hand, the cooking degrees of soybean which was steamed in an autoclave at $106-121^{\circ}C$ were compared by the maximum cutting forces. The cooking time to attain the same degree of cooking decreased logarithmically as the cooking temperature increased. The z-values which were calculated from the time-temperature combinations that gave the same degree of cooking for Jangyup and Whangkeum were $13.3^{\circ}C$ and $12.8^{\circ}C$ respectively.

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Oxidation of Each Carbon of Lactate in Various Cancer Tissues of Human (인체 각종 암조직에 있어서 젖산 각탄소의 산화과정)

  • Lee, Chong-Hun;Rhee, Sang-Don
    • The Korean Journal of Physiology
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    • v.3 no.1
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    • pp.11-18
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    • 1969
  • Tissue homogenates of 10 kinds of human cancer tissues were incubated in medium containing either one of $C^{14}-1,\; C^{14}-2,\;or\; C^{14}-3-lactate $ as a substrate in order to observe the oxidative pathway of lactate in cancer tissues. Lactate concentration in incubation medium was maintained at 50 mg%. At the end of incubation period, gas samples and incubation media were analyzed for total $CO_2$ production rates, radioactivities of respiratory $CO_2$, lactate uptake rates and pyruvate appearance rates. The following results were obtained. 1. Lactate uptake rates in all of cancer tissues examined were less than $2.5\;{\mu}M/hr/gm$ and much lower than those in normal tissues. 2. In the 10 kind of human cancer tissues, total $CO_2$ production rates were less than $10\;{\mu}M/hr/gm$, in all cases. These lower values impressed that oxidative metabolism in tumor tissues generally inhibited as compared with that in normal tissue. On the other hand, fractions of $CO_2$ derived from lactate to total $CO_2$ production rates were less than 15% except one case These facts showed that oxidation of lactate into $CO_2$ was greatly inhibited in tumor tissues. 3. Respiratory $CO_2$ yields from C-1 carbon of lactate in various cancer tissues were mean of 77.7% of total $CO_2$ yield from lactate and $CO_2$ yields from C-2 and C-3 carbon of lactate were mean of 9.1% and 12.6% respectively. These facts showed that carboxyl carbon of lactate oxidized more easily than ${\alpha}\;and\;{\beta}$ carbon of lactate. 4. In 10 kinds of cancer tissues, fractions of disappeared lacteate from media into $CO_2$ and pyruvate, which expressed as RLD $co_2$ and RLDpy respectively, were about 5% in except 3 cases and less than 3% except one case. These fact showed that almost of disappeared lactate from media were degraded into compounds other than $CO_2$ and pyruvate. From the above date, it was suggested that in the oxidative pathway of lactate in cancer tissues $CO_2$ was easily Produced from carboxyl carbon of lactate by oxidative decarboxylation as in the normal tissue, and further oxidation of 2 carbon unit via TCA cycle was inhibited.

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A Study on the Impact of Customer Equity on Customer Loyalty in the Korean Retail Industry: Mediation of Customer Satisfaction and Switching Costs (고객가치가 고객충성도에 미치는 영향에 관한 연구: 고객만족과 전환장벽을 매개변수로)

  • Kim, Soon-Hong
    • Journal of Distribution Science
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    • v.10 no.11
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    • pp.79-88
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    • 2012
  • Purpose - The objective of this paper is to suggest that a company's CRM activities have an effect on customer loyalty in the Korean retail industry. Typically, Korean customers use large local marts with convenience in the absence of any other choice. Therefore, this study aims to shed light on the fact that customers do not break away from their preferred retail stores, either owing to their stringent loyalty (the lie loyalty) or difficulty in turning to alternative choices. Research design, data, methodology - By surveying a sample of 200 hyper-markets through a questionnaire, and excluding dubious and missing responses, I obtained 181 samples to be included in the empirical analysis. The survey was conducted for two weeks during October 2011. AMOS and SPSS18 statistical packages were used for conducting statistical analysis for this study. This paper was developed using the concept of customer equity on CRM, which is known to have a positive impact on customer loyalty through the satisfaction and switching-barrier parameters. The hypothesis of this paper is that customer equity is composed of relationship equity, value equity and brand equity, and that the relationship equity variable has positive effects on the value equity and brand equity amongst other types of customer equity. Moreover, customer equity influences customer loyalty through parameters including customer satisfaction and switching costs in the Korean retail industry. Results - According to the results of the analysis, it was confirmed that relationship value had a positive effect (+) on all variables, including the perceived QoS (Quality of Service), store brand images, economic value, and store convenience. It was also confirmed that the assumption that the perceived QoS (Quality of Service), economic value, and store convenience had a positive effect on customer satisfaction was shown to be statistically significant, with a p-value below 0.05. Only the store brand value variable had an effect on the switching-cost variable with respect to the causal sequence of the variables, including the perceived QoS, store brand value, economic value, and store convenience. The remaining variables did not seem to influence the switching-cost variable. On the other hand, another effect showed that customer satisfaction had a statistically significant influence on the switching-costs variable. Moreover, the customer satisfaction and switching-cost variables also had a statistical influence on customer loyalty. Conclusions - The CRM activities had an influence on various variables (including perceived QoS, perceived economic value, store brand value, and store convenience) pertaining to customer values. Customer satisfaction and switching-cost had some effects on customer loyalty as a parameter. This confirms that stringent loyalty exists with respect to customer loyalty in the retail industry. The fact that the variable had such a statistically significant influence on the switching-cost and store brand equity variables means that consumers react to the reputation of a brand, confidence about the store, and quality confidence. The implications of this study in the retail industry should be further extended to devise strategies for customer retention.

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The Effects of Service Qualities on Customer Satisfaction and Behavioral Intention in Coffee Shops (커피전문점의 서비스품질이 고객만족과 행동의도에 미치는 영향)

  • Kim, Ho-Sik;Shim, Jae-Hyun
    • The Journal of Industrial Distribution & Business
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    • v.8 no.5
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    • pp.95-109
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    • 2017
  • Purpose - The purpose of this study is to classify the quality factors of coffee shop customers with the service quality based on the SERVQUAL, selection attributes, and service qualities used in previous studies. The path structure of coffee shops' quality factors → customer satisfaction → trust → behavioral intention was analyzed in order to confirm the system of coffee shops' quality factors. Research design, data, and methodology - The survey of was conducted with college students of Kangwon University. A total of 250 questionnaires were distributed, with 232 collected. Of them, Excluding 36 respondents' because of incomplete answers and missing values, 196 responses were used in the final analysis. Empirical analysis was made through factor analysis, correlation analysis, multiple regression analysis, simple regression analysis and mediating regression analysis by using Statistics Package SPSS 19.0. Results - The results are as follows: Firstly, coffee shops' quality factors were classified into seven categories like service encounter quality, product quality, cleanliness, overall interior, purchase quality, convenience, and aesthetics. Secondly, service encounter quality, product quality, purchase quality, and aesthetics had a positive effect on customer satisfaction, respectively. Thirdly, it showed that service encounter quality, product quality, overall interior, purchase quality, and aesthetics had a positive effect on trust, respectively. Fourthly, customer satisfaction had a positive effect on behavioral intention. Lastly, after verifying the effect relations of trust between customer satisfaction about coffee shop and behavioral intention, customer satisfaction has a positive effect on trust and trust has a positive effect on behavioral intention. On the other hand, trust did not have a mediating effect between customer satisfaction and behavioral intention. But, cleanliness, convenience, and overall interior did not have a positive effect on customer satisfaction. Conclusions - Coffee shop consumers put importance on price, discount systems, taste, and freshness, but more on courteous and kind services of coffee shop staff or comfortable and calming atmosphere of inner space. Thereby, coffee shop marketers need to take factors like service encounter quality and aesthetics into more consideration. In addition, customer satisfaction has an effect on trust, while trust on behavioral intention, even though trust is not mediated between customer satisfaction and behavior intention.

Analysis the Multicultural Society Impact on the Local Community (다문화사회가 지역공동체에 미친 영향분석)

  • Park, Jong Gwan
    • The Journal of the Korea Contents Association
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    • v.15 no.12
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    • pp.222-233
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    • 2015
  • In this study, the fact that the influx of multi-cultural society impact on local communities are examined to analysis the negative impact and positive impact with four types of political (government), economic, social and cultural saw classified. Although some have a negative evaluation, most of the respondents said the influx of multi-cultural society had a positive impact on South Korea's development and believes a positive impact in the future. In the results of the analysis, areas where multicultural society gives the most positive impact of local communities in political (administrative), economic, social, of the four segments of culture has been rated as the field of culture, on the other hand, areas that have the most negative impact has been evaluated as social sector. Though we live in nationalism culture for a long time and heterogeneous foreign residents has so rapidly increased that conflicts due to collision of values of differences and culture of each other have occurred, foreign residents are generally, have a positive impact on our society. Substantially marriage immigrants who successfully solve the rural bachelor of marriage problem are willing to prevent population decline phenomenon and reduce the crime rate in the society, of course. In addition, foreign workers who employed at low wages in the 3D industry which is avoided by the South Korean people have contributed to our country's economic development.

Comparison of Synchronization Phenomenon & the Changing Rate of the Charter Rates by major cities - Korea, Seoul, Busan, Daegu, Gwangju, Daejeon - (주요 도시별 전세가율의 동조화 현상과 변동률 비교 - 전국, 서울, 부산, 대구, 광주, 대전 -)

  • Choi, Jeong-Il;Lee, Ok-Dong
    • Journal of Digital Convergence
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    • v.18 no.2
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    • pp.197-204
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    • 2020
  • The purpose of this paper is to find the direction by analyzing the synchronization phenomenon and the change rate of apartment charter rate in Korea, Seoul, Busan, Daegu, Gwangju and Daejeon. For this purpose, this study used a total of 239 monthly data from January 2000 to November 2019 in Kookmin Bank housing statistics. In the correlation analysis, Korea showed the highest relationship in order of Seoul, Busan, Incheon and Daegu. Seoul showed a low figure of 0.3 without any distinctive features from other cities. On the other hand, Busan, Daejeon and Daegu showed high correlations. As a result of the regression analysis, Korea and 5 major cities were all moving in the same direction with positive(+) values. And Busan and Seoul responded significantly to Korea. In the shock response, Korea is most shocked by the change in Seoul. Daegu is relatively shocked by Busan and Daejeon. Seoul's charter rate has declined most strongly in the last three years. Therefore, it is time to be careful not to incur losses due to gap investment. If we look at the relationship between the charter rate and the sale price in future studies, we can better understand the Korean apartment market.

Pulsed Field Gel Electrophoresis Profile of Erythromycin-Clindamycin Resistant Streptococcus pyogenes Isolated in Korea (국내분리 Erythromycin-Clindamycin 내성 Streptococcus pyogenes에 대한 Pulsed Field Gel Electrophoresis 양상 분석)

  • Lee, Young-Hee;Hwang, Kyu-Jam;Lee, Kwang-Jun;Park, Kang-Soo;Bae, Song-Mee;Sung, Hwa-Young;Kim, Ki-Sang;Lee, Chong-Sam
    • The Journal of the Korean Society for Microbiology
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    • v.35 no.2
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    • pp.171-180
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    • 2000
  • Ninety two strains of Streptococcus pyogenes were isolated from patients with pharyngitis, scarlet fever, skin infection, and invasive streptococcal infections in Seoul, Korea from January to December, 1998. All isolates were epidemiologically characterized by T protein serotype, and serum opacity factor (OF) detection to phenotypes. To analyze the genetic relationship, fifty two isolates including 32 erythromycin-clindamycin (Em-Cm) resistant strains, 20 antimicrobial susceptible strains were attempted to the pulsed-field gel electrophoresis (PFGE). T protein serotype showed 16 kinds in distribution including T12 and T4. Among the total isolates, 40 strains (43.5%) belonged to the T12 serotype and twenty strains (21.7%) to T4 serotype. On the other hand, when infection aspect of S. pyogenes isolates were analysed by T serotype distribution, T12 type was predominant for pharyngitidis which contributed to 21 strains (53%) and for skin infection isolates which contributed to 11 strains (28%), respectively. In case of T4 type, it was the most predominant pharyngitidis isolates which contributed to 8 strains (40%). In T serotype distribution of Em-Cm resistant strains, 27 strains (84%) of the thirty two showed T12 serotype. In minimum inhibitory concentration (MIC) values of Em-Cm resistance isolates, thirty two isolates showed resistant to erythromycin 27 strains (84%), had high MIC of >$128\;{\mu}g/ml$. And also to clindamycin, twenty two strains (69%) had high MIC of >$128\;{\mu}g/ml$. When OF detection of Em-Cm resistance of S. pyogenes isolates were analyzed by T serotype distribution, T12 serotype isolates revealed that all of the isolates except one strain were OF negative. In PFGE profile analysis to Em-Cm resistance isolates, of the twenty seven, Em-Cm resistance of T12 serotype isolates, 26 strains showed identical PFGE profile and all of these isolates revealed that OF negative. Eighty four percent of Em-Cm resistance S. pyogenes isolates had identical phenotype and PFGE profile. These results strongly suggested that the Em-Cm resistant S. pyogenes isolates from Seoul area showed close genetic correlation and PFGE could be available tool for molecular epidemiology.

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