• Journal of Ginseng Research
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• v.13 no.1
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• pp.24-29
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• 1989

The tumoricidal activity of marine macrophage against K562 tumor cells was studied in the presence of lipopolysaccharide(LPS) and ginseng saponin. 1 The tumoricidal activity was increased more by LPS treatment with ginseng saponin (44% in 24 hours) than by LPS only (22% in 24 hours). In the case of diol saponin, the tumoricidal activity was increased as much as 35% at concentrations of 10-3 to 1034%. Triol saponin increased the tumoricidal activity more than LPS only treatment at each concentration . 2. When total, dial and triol saponin were added to K.562 tumor cell in various concentration without macrophage, it was found that the ginseng saponin hall no tumoricidal effect. This result suggests that ginseng saponin increases the tumoricidal activity of K562 tumor celts through the tumoricidal activity of the macrophage.

• Journal of Korean Academy of Nursing Administration
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• v.17 no.1
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• pp.54-65
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• 2011

Purpose: The aim of this study was to evaluate the efficiency of community visiting health service units using DEA and to compare the results with those of traditional evaluation methods. Methods: Data were collected using 2008 annual reports of 10 districts in one city. Input variables were number of staff and operational budget per year and output variables were number of managed household per nurse, rate of controlled hypertension, and diabetes mellitus. EMS Window version 3.1 was used to measure efficiency score and bootstrapping Chi-square test was applied to identify differences between efficient and non-efficient unit by organizational factors. Results: The average efficiency score of 10 community visiting health services was about 66%. Only two of the units operated program efficiently. The career of the staff was one among other factors associated with efficiency. The evaluation results from the traditional method and DEA were totally different. Conclusion: These results indicate that, evaluation methods have very important and significant effects on the evaluation results of community visiting health service units. The DEA method is recommend as an alterative method for evaluating community visiting health service.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.1608-1611
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• 2009

Here the hydrogen passivation treatment has been adopted to enhance the performance of poly-Si crystallized by YAG laser annealing (LA poly-Si). We have investigated the effects of passivation time, passivation power and passivation temperature on the hall mobility of the LA poly-Si and analyzed the mechanism of the hydrogen passivation preliminary. It has been found that the quality of the poly-Si annealed by YAG laser could be improved after proper hydrogen plasma treatment.

• Proceedings of the KIEE Conference
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• 1998.07a
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• pp.343-345
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• 1998

By computer simulation, the pattern of magnetic field distribution on the Nb-foil of a rotating flux type superconducting power supply has been calculated. Using the results, the current pumping rate has been calculated and compared with the results obtained by the experiment. The experiment has been executed with small-size flux-rump in the environment of LN2 and LHe in order to compare the pattern of magnetic filed in the superconducting state and in the normal state. Five hall-sensor was located on the center, right side, left-side, upper side, lower side of the Nb-foil in order to obtain more accurate pattern of the magnetic field generated by rotating pole. In the simulation, the effects of the excitation-magnet and the iron core located at the inner-side and circumference of the magnet have been considered. By comparing the data from the experiment and the results from the simulation, the size of normal spot estimated. At the same time, by calculating the linkage flux, the current-pumping-rate has been obtained. Consequently, the results obtained from experiment and simulation coincided as expected.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2004.03a
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• pp.703-712
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• 2004

A variant of the magnetoplasma jet engine (magjet) is here proposed for airbreathing flight in the hypersonic regime. As shown in Figure 1, the engine consists of two distinct ducts: the high-speed duct, in which power is added electromagnetically to the incoming air by a momentum addition device, and the fuel cell duct in which the flow stagnation temperature is reduced by extracting energy through the use of a magnetoplas-madynamic (MPD) generator. The power generated is then used to accelerate the flow exiting the fuel cells with a fraction bypassed to the high-speed duct. The analysis is performed using a quasi one-dimensional model neglecting the Hall and ion slip effects, and fix-ing the fuel cell efficiency to 0.6. Results obtained show that the specific impulse of the magjet is at least equal to and up to 3 times the one of a turbojet, ram-jet, or scramjet in their respective flight Mach number range. Should the air stagnation temperature in the fuel cell compartment not exceed 5 times the incoming air static temperature, the maximal flight Mach number possible would vary between 6.5 and 15 for a magnitude of the ratio between the Joule heating and the work interaction in the MPD generator varied between 0.25 and 0.01, respectively. Increasing the mass flow rate ratio between the high speed and fuel cell ducts from 0.2 to 20 increases the engine efficiency by as much as 3 times in the lower supersonic range, while resulting in a less than 10% increase for a flight Mach number exceeding 8.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.425-432
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• 2021

The purpose of this study was to examine the mediating effects of Informal Learning Activity on the relationship between Cultural Contents Industry Workers' Protean Career Attitude and Career Commitment. The results of this study were as follows: First, Protean career attitude of cultural contents industry workers had positive effect on career commitment. Second, Informal learning activity of cultural contents industry workers had partial mediating effect on the relationship between protean career attitude and career commitment. Based upon these results, several suggestions were suggested to promote cultural contents industry workers' protean career attitude, career commitment, and informal learning activity.

• BMB Reports
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• v.56 no.2
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• pp.114-119
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• 2023

Liver fibrosis is caused by chronic liver damage and results in the aberrant accumulation of extracellular matrix during disease progression. Despite the identification of the HAT enzyme p300 as a major factor for liver fibrosis, the development of therapeutic agents targeting the regulation of p300 has not been reported. We validated a novel p300 inhibitor (A6) on the improvement of liver fibrosis using two mouse models, mice on a choline-deficient high-fat diet and thioacetamide-treated mice. We demonstrated that pathological hall-marks of liver fibrosis were significantly diminished by A6 treatment through Masson's trichrome and Sirius red staining on liver tissue and found that A6 treatment reduced the expression of matricellular protein genes. We further showed that A6 treatment improved liver fibrosis by reducing the stability of p300 protein via disruption of p300 binding to AKT. Our findings suggest that targeting p300 through the specific inhibitor A6 has potential as a major therapeutic avenue for treating liver fibrosis.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.2
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• pp.219-227
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• 2022

In Korea, as the aging phenomenon accelerates, the problem of traffic accidents related to the elderly is continuously emerging. Efforts to improve this are being implemented, but unfortunately the results of these effects are not clear. Therefore, in this study, the effect of traffic characteristics and incentive policies on the return of driver's licenses of elderly drivers was reviewed. As a result of the analysis, it was confirmed that the intention to return the driver's license was low in the case of men, older people, those with low dependence on public transportation, those who undertook long driving hours, and those who took frequent trips. On the other hand, financial incentives were found to play a positive role with regard to the intention to return the driver's license. However, the effect is expected to be insignificant for those with a low intention to return the driver's license. As a result, under the current policy, it is predicted that there is a limit to improving the social problems caused by elderly drivers, meaning that it is necessary to review approaches that induce the return of their driver's licenses.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.161-163
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• 2021

This urban centralization is expected to develop rapidly, with 75% of the population living in the city by 2035. Large cities are becoming unsustainable due to side effects such as environmental pollution, severe traffic jams, excessive energy depletion, and destruction of the natural ecosystem. In addition, the happiness index of citizens of large cities is also falling because of high crime rates and safety accidents, the work-life imbalance caused by inequality and polarization, and overly competitive education. To solve this problem, Smart City, an IT-based future city model, was born. The Korean government is also actively attempting to improve urban competitiveness and promote sustainable development through efficient construction and operation of smart cities as a national focus project. To support the effort, we review the basic directions and strategies of Sejong City's Smart City service infrastructure based on the comprehensive national land plan, Smart City plan, and Smart City strategy plan.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.2
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• pp.357-367
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• 2017

Bending and axial forces simultaneously occur at the cross-section of a shotcrete lining reinforced with steel supports due to the tunnel geometry. The shotcrete has changing flexural stiffness depending on the axial forces and, as a result, severely nonlinear behavior. The mechanical properties of a shotcrete-steel composite also depend on the type of steel support. This study presents a fiber section element model considering the effect of axial force to evaluate the nonlinear behavior of a shotcrete-steel composite. Additionally, the model was used to analyze the effects of different types of steel supports on the load capacity. Furthermore, a modified hyperbolic model for ground reaction, including strain-softening, is proposed to account for the ground-lining interaction. The model was validated by comparing the numerical results with results from previous load test performed on arched shotcrete specimens. The changes in mechanical responses of the lining were also investigated. Results show a lining with doubly reinforcement rebar has similar load capacity as a lining with H-shaped supports. The use of more materials for the steel support enhances the residual resistance. For all types of steel reinforcement, the contribution of steel supports during peak load decreases as the ground becomes stiffer.