• 한국식품과학회지
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• 제33권6호
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• pp.664-668
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• 2001

전통 천연 색소원인 홍화 꽃잎으로부터 추출한 적색소인 carthamin을 식품색소로 활용하기 위한 기초연구로 carthamin의 여러 가지 이화학적 안정성을 분해속도와 반감기를 구하여 조사하였다. Carthamin은 산성에서는 매우 불안정하여 반감기가 pH 3.0에서는 5.26시간, pH 5.0에서는 4.9시간으로 매우 짧았으며 중성(pH 7.0)에서는 11.1시간, 알칼리 조건(pH 11.0)에서는 45.1시간으로 조금 더 안정했으나 적색에서 각각 주황색과 노란색으로 변화하였다. 온도가 증가함에 따라 색소 분해속도가 급격히 증가하였다. 많은 식품들이 약산성이므로 첨가물에 의한 안정성은 pH 5.0과 3.0에서 조사하였는데 무기이온들을 첨가하였을 때 큰 변화는 없었으나 $Al^{3+}$ 첨가 후에 농색화 현상과 함께 분해속도가 감소하여 안정화효과를 나타내었다. 빛에 의해(20,000 lux) 색소 분해가 촉진되어 대조구에 비해 2-3배 단축된 반감기를 나타내었다. 단당류와 이당류에 의해서는 변화가 거의 없었고 다당류를 첨가한 경우 약간의 안정화 효과가 관찰되었으며, 특히 CMC(carboxymethylcellulose)에 의해 pH 5.0의 조건에서 증가된 반감기를 나타내어 앞으로의 안정화 기술 개발의 가능성을 보여주었다.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2011년도 춘계학술발표대회 논문집
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• pp.261-266
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• 2011

The purpose of this study was to identify the perception of residents on green home and their green residential life. For this study, a questionnaire survey was conducted and the items consisted of whether green home was perceived and how well green residential life was maintained in 6 types of environments. A total 118 responses of residents living in apartments of Seoul Metropolitan Area were used for data analysis. Using statistical program SPSS Win 18.0, frequency analysis, t-test, One-way ANOVA, and factor analysis was employed. The major findings were as follows: 1) slightly more than half of the respondents were aware of green home, and the vast majority were in favor of the green home policy; 2) most of the respondents carried out guidelines of green residential life, and in particular, green living on air environment was well done, followed by consumption, waste, energy, traffic and water; 3) the six kinds of environments were subcategorized by using factor analysis, and 3 to 5 factors were included in each category of environment. Also, it was found that age, educational level, employment status of respondents, housing tenure and duration were related to the degree of green residential life. In midst of global movement toward sustainability, environmentally friendly living is not optional but mandatory, so it's important to change each individual's value on the relation between people and environment and to facilitate more environmentally conscious behaviors.

• Journal of Preventive Medicine and Public Health
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• 제39권3호
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• pp.243-248
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• 2006

Objectives: The Quality of Life-Alzheimer's Disease (QOL-AD) scale is a reliable and valid tool for assessing the quality of life (QOL) in the elderly with dementia. This study aimed to develop the Korean version of Quality of Life-Alzheimer's Disease (KQOL-AD) scale for the demented elderly living in the community. Methods: KQOL-AD was administered to two groups: 24 demented elderly and 72 cognitively impaired elderly with no dementia (CIND) who were living in the community Each elderly person and their caregiver rated the elderly QOL. The Korean version of mini-mental state examination (MMSE-K), the clinical dementia rating (CDR), the activities of daily living (ADL), and the neuropsychiatric inventory (NPI) were also assessed. The reliability and validity of the KQOL-AD were examined. Results: In the dementia group, the internal consistency (Cronbach's $\alpha$), the split half and the test-retest reliabilities of the KQOL-AD were excellent. Scores on the KQOL-AD were significantly correlated with the scores of the NPI, but they were not significantly correlated with scores of the MMSE-K, CDR and ADL. In addition, the CIND group showed similar results to the dementia group. Conclusions: KQOL-AD might be a reliable and valid instrument for assessing QOL in the elderly with dementia It could be used as an important outcome measure for research on the demented elderly.

• 한국생활과학회지
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• 제22권2호
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• pp.375-389
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• 2013

This survey was conducted to compare the housewife's food habit and food purchase behavior on healthy dietary life. The questionnaires were collected from 151 working housewives and 159 housewives in Daejeon. The average meal time was 20~30 min., 67.6% of respondents ate breakfast and bap with guk(72.9%) was the most favourite foods. Almost half of them ate egg, fruit, vegetable everyday. They concerned highly about less intake of frozen foods(64.2%) and food additives(61.6%) for wellbeing dietary life. Because of close distance and various foods items, big discount store was chosen as food purchase place. The most considering purchase factor was food additives in working housewife and nutrition in housewife(p<0.05). In grocery shopping, working housewife considered children and their husbands(p<0.05). The most important purchase factor was the freshness in vegetables fishes fruits seaweeds eggs. TV or Radio was utilized the most frequently to obtain the useful knowledge on healthy foods. It is suggested that practical information should be offered housewives to purchase proper foods within their income and to manage dietary life according to their family's health condition.

• 한국공작기계학회논문집
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• 제16권4호
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• pp.64-70
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• 2007

This paper presents a study on the effects of feedrate and shotpeening on the fatigue life of A17075-T6 specimens. For this purpose, six groups of specimens, each of which consists of eight specimens, were first machined at six different feedrates(0.05, 0.10, 0.15, 0.20, 0.25, 0.30mm/rev). Half of eight specimens in each group were then peened and the others remained un-peened. Then, the fatigue life was measured by using 4-point rotatry bending machine. One observation was that the fast the feedrate was, the large the diameter of a specimen was. To make sure that the bending stress was the same in all cases, different loading conditions were thus applied to specimens based on their diameters. Next, comparison of fatigue life among twelve sets of specimens(six groups times two sets, peened and un-peened) was performed. Finally, based on machining cost analysis, a guideline for optimal feedrate was presented.

• Journal of Community Nutrition
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• 제1권2호
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• pp.133-139
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• 1999

The purpose of this survey was to investigate eating habits, life styles and nutritional care of diabetic outpatients and to provide basic data for developing individualized nutritional care and diabetic education programs. This survey was carried out by nutritional counseling with a questionnaire and checking medical record. Information about the general characteristics of the subjects, eating habits, health-related life styles and attitude and perception of subjects to diet therapy was gathered from 200 randomly-sampled diabetic outpatients at a University Hospital located in Inchon. All data were analyzed by Statistical Analysis System(SAS) software. The results are summarized as follows : Female subjects were 63.5% of total subjects and 65.5% of total subjects were 50 years or more. The average Body Mas Index(BMI) of male and female subjects were 23.06kg/㎡ and 25.02kg/㎡ respectively and 44% of all subjects wee obese. Among subjects, type II diabetic patients were 81.0% and 82.5% of subjects had suffered from diabetes for more than one year. Also 41% subjects had diabetic history in their family. More than half of the subjects had nutrition education concerning diabetes. Also 75.5% of them thought that nutrition education was effective. The most important guideline in diet therapy was to eat cooked rice with dietary fiber-rich grains. Therefore, it might be necessary to develop nutrition education program adjusted according to diabetic patient's needs and life styles, which may increase feasibility of self-care and implementation of management guidelines.

• 식물분류학회지
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• 제48권3호
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• pp.218-229
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• 2018

Myanmar's plant diversity is expected to be very high given the wide variety of climates and the diverse vegetation and geographical features of the country. Since the publication of Kress et al.'s plant checklist in 2003, new and unrecorded species have been constantly reported by various botanists, but much of Myanmar's flora requires more intensive examinations. We conducted joint floristic surveys of several Ywangan areas, including the Panlaung-Pyadalin Cave Wildlife Sanctuary in southern Shan State of Myanmar. The initial identification of seed plant specimens collected from three short floristic expeditions revealed that 23 species were newly recorded species in Myanmar. More than half of these were found to be geographically notable species, which are known to be endemic to neighboring countries such as China (4 spp.), Thailand (6 spp.), and India (2 spp.). A considerable number of these unrecorded species are distributed in the limestone areas of neighboring countries, reflecting the geological characteristics of the survey area. The results of this study reemphasize the need for intensive and continuous research on the flora of Myanmar for a more comprehensive understanding of the distribution patterns of flowering plants in Southeast Asia.

• 보건의료기술평가
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• 제6권2호
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• pp.133-141
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• 2018

Objectives: In the past, the pharmaceutical drug heparin was mostly used as the anticoagulant for continuous renal replacement therapy (CRRT), but the duration time is long to have the risk of a bleeding adverse effect, and in that case the drug therapy Nafamostat mesilate was utilized instead, as it is more safe in this case, with a short half-life and is increasing in use to permit lower concerns for bleeding incidents. However, there are insufficient number of large-scale studies on the comparison of Nafamostat mesilate and heparin. Methods: In this study, a systematic review are used to compare the bleeding risk of Nafamostat mesilate and Heparin, as subjected to patients and procedures for measuring risks performed with a CRRT, and the filter life span is to be evaluated as well in this patients. Results: As a result of literature review search, a total of 6 studies were included in systematic review. The reducing risk of bleeding and filter life span was analyzed. The retrospective cohort studies confirm that Nafamostat mesilate is less at risk of bleeding than heparin. And a cohort study confirms that Nafamostat mesilate is longer filter lifespan than heparin and randomized controlled trial studies show that Nafamostat mesilate is longer filter lifespan than not using the anticoagulants. Conclusion: Nafamostat mesilate is considered to be a good therapeutic option because it has a longer filter life span as well as the advantage of reducing bleeding.

• 대한금속재료학회지
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• 제49권7호
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• pp.541-548
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• 2011

Thermomechanical fatigue (TMF) behavior of heat resistant austenitic stainless steel was evaluated in the temperature range from 100$^{\circ}C$ to peak temperatures of 600 to 800$^{\circ}C$; The fatigue lives under TMF conditions were plotted against the plastic strain range and the dissipated energy per cycle. In the expression of the inelastic strain range versus fatigue life, the TMF data obtained at different temperature ranges were located close to a single line with a small deviation; however, when the dissipated energy per cycle, calculated from the area of the stress-strain hysteresis loops at the half of the fatigue life, was plotted against the fatigue life, the data showed greater scattering than the TMF life against the inelastic strain range. A noticeable stress relaxation in the stress-strain hysteresis curve took place at the peak temperatures higher than 700$^{\circ}C$, but all specimens in this study exhibited cyclic hardening behavior with TMF cycles. Recrystallization occurred during the TMF cycle concurrent with the formation of fine subgrains in the recrystallized region, which is considered to cause the cyclic hardening of the steel.

• Natural Product Sciences
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• 제27권1호
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• pp.28-35
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• 2021

The aim of this study was to anatomize the therapeutic potential of alaternin (=7-hydroxyemodin) against inflammation, advanced glycation end products (AGEs) formation, tyrosinase, and two cyclin-dependent kinases (CDKs), CDK2 and CDK4, and compare its potency with emodin. Alaternin showed lower cytotoxicity and higher dose-dependent inhibition against lipopolysaccharide (LPS) induced nitric oxide (NO) production with half maximal inhibitory concentration (IC50) of 18.68 µM. Similarly, alaternin efficaciously inhibited biotransformation of fluorescent AGEs and amyloid cross-β structure on the bovine serum albumin (BSA)-glucose-fructose system, five times more than emodin. Interestingly, alaternin also showed selective activity against CDK4 at 170 µM, whereas emodin inhibited both CDK2 and CDK4 at a concentration of 17 and 380 µM respectively. In addition, alaternin showed dose-dependent inhibitory activity against mushroom tyrosinase with inhibition percentage of 35.84 % at 400 µM. Altogether, alaternin with pronounced inhibition against inflammatory mediator (NO), glycated products formation, and targeted inhibition towards CDK4 receptor can be taken as an important candidate to target multiple diseases.