• 제목/요약/키워드: Half Life

검색결과 1,829건 처리시간 0.031초

소아청소년 집단에서 집단 따돌림의 유병률과 이와 관련된 정신병리 현상 (Prevalence of School Bullying and Related Psychopathology in Children and Adolescents)

  • 권순재;박태원;박선희;양종철;정영철;정상근
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • 제23권3호
    • /
    • pp.143-153
    • /
    • 2012
  • Objectives : This study examined the current prevalence rate of school bullying and its related psychopathology. Methods : A total of 3,550 elementary/middle school students and their parents were recruited for this study. A self-report questionnaire on perpetration and victimization in school bullying was used for collection of data regarding prevalence and the present state of school bullying. For evaluation of associated psychopathology, self report forms, including the Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), attention-deficit hyperactivity disorder Rating Scale (ARS), Korean-Child Behavior Checklist (K-CBCL), Korean-Youth Self Report (K-YSR), and the Korean Eppendorf Schizophrenia Inventory (K-ESI) were applied. Samples were classified according to four subtype groups (control, victim, perpetrator, and victim-perpetrator) and characteristics of each group were compared. Results : Overall, the prevalence rate for bullying perpetration was 64.4% and the prevalence rate for bullying victimization was 63.4%, indicating involvement of more than half of students in school bullying. Bully-victims reported high social immaturity and depressive and suicidal tendency, whereas bully-perpetrators reported less social immaturity and more externalizing problems. Among the subtype groups, the victim-perpetrator group showed the most prominent depressive/anxiety tendency and behavioral problems. Conclusions : Both victimization and perpetration of bullying are common problems for child and adolescent groups and several psycho-social problems were found to be related. The results of this study will guide direction of future study and development of strategies for prevention of bullying.

Consecutive automated production of carbon-11 labeled radiopharmaceuticals by sharing 11C-methylation reagent from one 11C-synthetic module

  • Park, Hyun Sik;Lee, Hong Jin;An, Hyun Ho;Moon, Byung Seok;Lee, Byung Chul;Kim, Sang Eun
    • 대한방사성의약품학회지
    • /
    • 제2권2호
    • /
    • pp.123-131
    • /
    • 2016
  • Increasing clinical demand for carbon-11 labeled radiopharmaceuticals has triggered technological advances in fields of radiochemistry and automated modules. Even though carbon-11 has a short half-life ($t_{1/2}=20.4min$), the consecutive second production of carbon-11 labeled radiopharmaceutical in one $^{11}C$-synthetic module should be delayed at least over 4 h to avoid the high radiation exposure. We herein aimed to produce two different carbon-11 labeled radiopharmaceuticals ([$^{11}C$]PIB and [$^{11}C$]methionine) by sharing of [$^{11}C$]methylation source in one $^{11}C$-synthetic module. The synthesis of $^{11}C$-labeling reagents ($[^{11}C]CH_3I$ or $[^{11}C]CH_3OTf$) is fully automated using the commercial TRACERlab $FX_{C-pro}$ module and is readily adaptable to $^{11}C$-labeling reactor for [$^{11}C$]PIB as well as another $^{11}C$-labeling apparatus for [$^{11}C$]methionine via the three-way valve. After completing the [$^{11}C$]PIB production, the re-synthesized $[^{11}C]CH_3I$ was passed through the three-way valve connected the polyetheretherketone (PEEK) line and loaded into the C18 Sep-Pak cartridge including the methionine precursor. The labeled product [^${11}C$]methionine was purified by a simple cartridge separation and reformulated into saline. The radiochemical yield of [$^{11}C$]PIB and [$^{11}C$]methionine were $5.3{\pm}0.6%$ and $18.7{\pm}0.8%$ (n.d.c.), respectively, with over 97% of radiochemical purity. The specific activity of [$^{11}C$]PIB was over $110GBq/{\mu}mol$. Total production time of two radiopharmaceuticals needs about 2 h from $1^{st}$ beam irradiation including quality control tests. Final [$^{11}C$]PIB and [$^{11}C$]methionine were satisfied all quality control test standards.

교육적으로 유의미한 의사소통을 위한 지구과학 관련 전시 라벨의 서술 특징 (Descriptive Characteristics of the Label Texts Related to Earth Science: Toward Educationally Meaningful Communication)

  • 김찬종;박은지;윤세열;이선경
    • 한국지구과학회지
    • /
    • 제33권1호
    • /
    • pp.94-109
    • /
    • 2012
  • 본 연구는 국내 주요 과학관 및 자연사 박물관의 지구과학 관련 전시 라벨 텍스트의 서술 특징을 분석하고자 하였다. 이를 위해, 국립 중앙 과학관과 서대문 자연사 박물관에서 자료를 수집하였고, 체계기능언어학을 일부 적용한 분석틀을 사용하였다. 연구 결과, 라벨들은 1) 대부분 평서형 문장, 2) 적절한 과학적 정보의 양, 3) '사실' 위주의 정보 제시, 4) 모두 논리적 설명 장르로 구성되어 있었다. 특히, 국립 중앙 과학관의 라벨들은 5) 전체 어휘 중 과학 용어의 비율이 높고 6) 주어의 절반 이상이 생략되거나 긴 명사화 형태였다. 결론적으로, 분석 대상 라벨들은 전시물과 관람객들 사이에서 과학 문화에 관한 양 방향적 의사소통을 이끌기보다 일 방향적인 의사소통을 일으킬 가능성이 높은 것으로 해석할 수 있었다. 이를 토대로, 과학 문화와 관람객의 일상 문화 사이의 열린 구조를 만들어 보다 교육적으로 유의미한 의사소통을 가능하게 하는 라벨 텍스트의 서술 특징들을 제안하였다.

여자 저고리 소고 (A study on the upper garment of Korean women, Jugori)

  • 이경자
    • 대한가정학회지
    • /
    • 제8권1호
    • /
    • pp.62-86
    • /
    • 1970
  • A study on the upper garment of Korean women, JUORI The upper garment of Korean women. JUGORI, is an inherited mode from the ancient clothing style in the various aspects based on the particulars of Korean clothes. The ancient style of clothes is originated from KWAMDUI belonging to inhabitants of Northern Territory of Korea. And it is quite different from Chinese clothes in lineage. However, this unicque mode of clothes has been much influnced by the Chinese culture and also by the climate of Korea. And it is quite different from Chinese clothes in lineage. However, this unicque mode of clothes has been much influnced by the Chinese culture and also by the climate of Korean penynsula. The changes of the pattern of JUGORI, in a word, is a sign of shortening tendency of size. This tendency of JUGORI is remarkably seen in the shortening of length and other parts are decreased in size. The JUGORI in the ancient age was fallen below the weist of woman, which is similar to Robe, and was worn with band. However, the length of the JUGORI has been gradually shortened, and therefore, GORUM took place of the band. The shortening tendency of JUGORI is seemed to be shown its sign in the initial time of its origin, because there are some evidences that the women in Sylla Dynasty, and this tendency has been much expedited during the period of Koryu Dynasty with influences of Monggorian culture (Won Lynasty of China) The oldest sample for data of JUGORI in nowaday is one the remains of Yi Dynasty, and this sample for data provides all the particulars of the modern pattern of JUGORI. The tendency of JUGORI had been continued even in Yi Dynasty, and at the end of the Dynasty, the clothes was shortened that the women felt inconvenient wearing it in the status of the shortened JUGORI which was even hardly cover the initial time of epoch of modernization induced from the Western civilization, and after 1920s and 1930s JUGORI become a larger tendency. This is a sing of revival of practical use and rationalization of JUGORI become a shortening tendency again, and the size is similar with that of early age of Yi Dynasty. Instead of these similarities, the particulars of modern JUGORI is weighing on much emphasis on curve beauty and expression of experior beauty. The reason is that, together with westernization of clothes, JUGORI became a special pattern of clothes as a traditional Korean women wears. The very thing explaining this pattern of JUGORI is the "ARIRANG DRESS". And there are some fashion using button instead of GORUM and half sleeve JUGORI for summer use which is regarded as a part of improved aspect of life in Korea. in Korea.

  • PDF

류마티스 관절염 환자에서 Methotrexate에 의해 발생한 간질성 폐렴 1예 (A Case of Methotrexate Induced Pneumonitis in a Patient with Rheumatoid Arthritis)

  • 박찬석;이상학;심건호;김완욱;이숙영;김석찬;김관형;문화식;송정섭;박성학
    • Tuberculosis and Respiratory Diseases
    • /
    • 제57권3호
    • /
    • pp.273-277
    • /
    • 2004
  • 저자들은 급성호흡곤란을 주소로 내원한 류마티스 관절염 환자에서 임상소견과 흉부 방사선소견, 기관지폐포세척액 및 경기관지폐생검을 통해 methotrexate에 의한 간질성 폐렴 1예를 진단하였기에 문헌 고찰과 함께 보고하는 바이다.

우울증의 자기 관리 방법 (Self Care in Depression)

  • 이선혜;박용천
    • 생물정신의학
    • /
    • 제14권1호
    • /
    • pp.5-13
    • /
    • 2007
  • Objectives : Depression disturbs the individual life from the loss of productivity to suicide. Furthermore the whole society is also influenced by depression in social and economic areas. Many scientific treatment methods are known to be effective in depression. But in reality more than half of patients with depression prefer self help treatment rather than medically based treatment. For the patients with mild depression and primary physicians, it is reasonable to provide the evidence based self care including self help or alternative treatment. This study is supported by the Korean Health 21 R&D Project for the Depression Center to establish the Korean treatment guideline for depression. Methods : The members of Depression Center including the authors attended the workshops where the methods of evidence based medicine such as literature search, quality evaluation of the articles, making the level of evidence were educated. The professional librarians helped the authors for get the searched articles. Among the total of 354 abstracts of systemic review and 300 abstracts of random controlled trials, 3 systemic reviews and 2 random controlled trials were the main structure of evaluation. Result : Among the 37 self care methods known to be effective for depression, 11 kinds of methods were worth of evaluation. The first step for the self care of mild depression is to use St. John's wort, exercise, bibliotherapy, and light therapy in depression during winter season. Acupuncture, negative ion therapy, massage, relaxation technique are known to be efective with evidence. Music therapy, hypnotherapy, and aromatherapy are known to be effective but until now the evidences is insufficient and further evaluations are needed. Conclusion : Among 11 listed self-care methods, several methods need more evidence especially in Korean situation. Exercise is the most recommendable evidence based self care method in Korea nowadays. St. John's wort is effective with evidence, but it is not the OTC drug in Korea, so it is not recommendable now. For the bibliotherapy, there is no book such as "Feeling Good" in Korea. Only the introductory book about depression is available. Publishing the self help book based upon cognitive behavioral approach or psychodynamic approach is needed. Light therapy is practiced in a few clinics, but not self-help style. Exposure to the sunlight is recommended in the level of commen sense. These self care methods are for the mild patient. Moderate to severe patients with depression should seek the professional treatment.

  • PDF

산업장 건강검진의 한의학적 모델 개발 연구 (Research on the Development of the Oriental Medical Model on the Health Examination in the Industry)

  • 정명수;김성천;이은경;천은주;한종민;이수경;강성호;유택수;정재열;송용선;이기남
    • 대한예방한의학회지
    • /
    • 제4권1호
    • /
    • pp.32-50
    • /
    • 2000
  • On the process of research in the plan on oriental medical participation in the industrial health sponsored by BK21 project, we carried out the oriental medical health examination program for workers during former half-year We reached the conclusion as follows, 1. The oriental medical health examination program is contents and formalities that should be determined by present industrial health system, based on the oriental medical system and scholastic character, and included probability of the western and oriental medical cooperation. 2. The oriental medical health examination program can promote capability of individual health management and productive power of workers, and it is capable to manage on the self-conscious symptoms and macroschophically approach to their environment 3. The oriental medical health examination program that we have developed, is flow as questionare, understanding of working environment, information of result and later management. It is composed of three fields as follow , first, use of pulse diagnostic apparatus, understanding of the health promotion life style, and diagnosis of the oriental medical doctor, second, analysis of constitution, third, photographing for understanding of the musculoskeletal disorders, questionare for musculoskeletal self-conscious symptoms, and diagnosis of oriental medical doctor. 4. The oriental medical health examination program that we have developed, progressive from the view point of health, makes the oriental medical doctor's roll more important. It is the first trial at the western and oriental medical cooperation and characterized by excellence about musouloskeletal disorders. But it need to be improved in aspects of time and specialist on the health examination, diagnostic apparatus, control of examinant and later management. So we think that it needs research on the employment of health examination specialist, establishment of later management system, development of significantly diagnosable standard and assessable form on the health examination, and contents of health examination on the western and oriental medical cooperation.

  • PDF

Re-188-DTPA (Diethylenetriaminepentaacetic acid)의 표지와 생체내 분포 (Labeling and Biodistribution of Re-188-DTPA (Diethylenetriaminepentaaceticacid))

  • 이진;김영주;장영수;정재민;신승애;정준기;이명철;고창순;이동수
    • 대한핵의학회지
    • /
    • 제31권4호
    • /
    • pp.427-432
    • /
    • 1997
  • Re-188은 반감기가 17시간이고 진단을 위한 영상화가 가능한 감마선(155keV)을 방출하며 치료용으로 적당한 베타선(2.12MeV)을 동시에 방출하여 혈관성형술 풍선에 넣어 조사하는 접촉 베타선 방출체 치료용 방사성핵종으로 유력하다. 이 연구에서는 Re-188-DTPA를 관상동맥풍선 성형술시 풍선에 주입하는 방사성 동위원소로 쓸 수 있을지 알기 위해 우선 표지법과 풍선에서 혈관내로 샜을 때의 생체내 분포를 조사하였다. Re-188과 DTPA를 표지하는 방법을 확립하였고 표지효율은 95%, 실온과 사람 혈청에서 안정하였다. 마우스의 체내분포와 랫트와 실험견에서 얻은 신장 시간방사능곡선이 Re-188-DTPA가 신장을 통해 빠르게 제거된다는 것을 밝혔다. 이러한 결과는 Re 188-DTPA를 관상동맥의 재협착을 방지하기 위해 관상동맥풍선 성형술시 풍선에 주입하는 방사성 동위원소로 사용하여도 좋음을 시사한다.

  • PDF

131I 치료입원실 폐기물 방사능 오염도 분석 및 자체처분가능일자 산출 (Determination of Self-Disposal date by the Analysis of Radioactive Waste Contamination for 1131I Therapy Ward)

  • 김기섭;정해조;박민석;정진성
    • 핵의학기술
    • /
    • 제17권1호
    • /
    • pp.3-6
    • /
    • 2013
  • Purpose: The treatment of thyroid cancer patients was continuously increased. According to the increment of thyroid cancer patients, the establishment of iodine therapy site was also increased in each hospital. This treatment involves the administration of radioactive iodine, which will be given in the form of a capsule. Therefore, protections and managements for radioactive source pollution and radiation exposure should be necessary for radiation safety. Among the many problems, the problem of disposing the radioactive wastes was occurred. In this study, The date for self-disposal for radioactive wastes, which were contaminated in clothes, bedclothes and trash, were calculated. Materials and Methods: The number of iodine therapy ward was 15 in Korea Institute of Radiological Medical and Sciences. Recently, 8 therapy wards were operated for iodine therapy patients and others were on standby for emergency treatment ward of any radiation accidents. Radioactive wastes, which were occurred in therapy ward, were clothes, bedclothes, bath cover for patients washing water and food and drink which was leftover by patients. Each sample was hold into the marinelli beaker (clothes, bedclothes, bath covers) and 90 ml beaker (food, drink, and washing water). The activities of collected samples were measured by HpGe MCA device (Multi Channel Analysis, CANBERRA, USA) Results: The storage period for the each kind of radioactive wastes was calculated by equation of storage periods based on the measurement outcomes. The average storage period was 60 days for the case of clothes, and the maximum storage period was 93 days for patient bottoms. The average storage period and the maximum storage period for the trash were 69 days and 97 days, respectively. The leftover foods and drinks had short storage period (the average storage period was 25 days and maximum storage period was 39 days), compared with other wastes. Conclusion: The proper storage period for disposing the radioactive waste (clothes, bedclothes and bath cover) was 100 days by the regulation on self-disposal of radioactive waste. In addition, the storage period for disposing the liquid radioactive waste was 120 days. The current regulation for radioactive waste self-disposing was not suitable for the circumstances of each radioactive therapy facility. Therefore, it was necessary to reduce the leftover food and drinks by adequate table setting for patients, and improve the process and regulation for disposing the short-half life radioactive wastes.

  • PDF

수치해석을 이용한 전동차용 IGBT 모듈의 피로 수명 예측 (Numerical Fatigue Life Prediction of IGBT Module for Electronic Locomotive)

  • 권오영;장영문;이영호;좌성훈
    • 마이크로전자및패키징학회지
    • /
    • 제24권1호
    • /
    • pp.103-111
    • /
    • 2017
  • 본 연구에서는 전동차의 전력 변환 장치로 많이 사용되고 있는 고전압 대전류용(3,300 V/1200 A급) insulated gate bipolar transistor(IGBT) 모듈에 대하여 열 사이클 조건하에서의 열-기계적 응력해석 및 피로수명해석을 수행하였다. 특히 최근 고전압 IGBT용으로 개발되고 있는 구리(copper) 와이어, 리본(ribbon) 와이어를 사용하였을 경우의 응력 및 피로수명을 기존의 알루미늄 와이어와 비교하여 분석하였다. 알루미늄 와이어 보다는 구리 와이어에 응력이 3배 이상 많이 발생하였다. 리본 와이어의 경우 원형 와이어 보다 응력이 더 크게 발생하며, 구리 리본 와이어의 응력이 제일 높았다. 칩과 direct bond copper(DBC)를 접합하고 있는 칩 솔더부의 피로해석을 수행한 결과, 솔더의 크랙은 주로 솔더의 모서리에서 발생하였다. 원형 와이어를 사용할 경우 솔더의 크랙은 약 35,000 사이클에서 발생하기 시작하였으며, 알루미늄 와이어 보다는 구리 와이어에서의 크랙의 발생 면적이 더 컸다. 반면 리본 와이어를 사용하였을 경우 크랙의 면적은 원형 와이어를 사용하였을 경우보다 적음을 알 수 있다. DBC와 베이스 플레이트 사이에 존재하는 솔더의 경우 크랙의 성장 속도는 와이어의 재질이나 형태에 관계없이 비슷하였다. 그러나 칩 솔더에 비하여 크랙의 발생이 일찍 시작하며, 40,000 사이클이 되면 전체 솔더의 반 이상이 파괴됨을 알 수 있었다. 따라서 칩 솔더 보다는 DBC와 베이스 플레이트 사이에 존재하는 솔더의 신뢰성이 더 큰 문제가 될 것으로 판단된다.