• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.4
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• pp.331-339
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• 2014

This study is aimed to provide the primary data about safety of cosmetics products using indirect preference of korean cosmetics customer and numerical comparison of applied area. For this study, we collected 9,879 cosmetics products which were inspected in cosmetics research team from January, 2010 to December, 2012. The domestic cosmetics was 645 cases (6.5%) and Imported cosmetics was 9,234 cases (93.5%). As manufacturing country, the France has 4,342 cases (44.0%) and the next ranking were like those, Germany 1,637 cases (16.6%), U.S.A 1,476 cases (14.9%), Republic of Korea 645 cases (6.5%), Italy 557 cases (5.6%), and etc 1,222 cases (12.4%). By the year, the cases of test cosmetics have decreased from 3,784 cases (2010), 3,394 cases (2011) to 2,701 cases (2012), the relative ratio of common cosmetics part was drop in but the other group (functional cosmetics and hair dye related products) was increased. The largest market share product was Skin care 5,470 cases (55.4%) and the next order was like those, Make up 1,908 cases (19.3%), Hand & Foot 1,026 cases (10.4%), Hair Care 616 cases (6.2%), Bath 361 cases (3.7%), and etc 498 cases (5.0%). In domestic cosmetics, the greatest proportion was Skin care and the others were Hair Care > Makeup > Hand & Foot > Bath, but the proportion was evidently changed in imported cosmetics, Skin care > Makeup > Hand & Foot > Hair Care > Bath. It is necessary to set the priority of the international quality standards to identify trends from domestic consumers directly or indirectly. Compare the ratio of category and human application parts from domestic and imported cosmetics, we utilize leverage as the basis for future-oriented cosmetic safety.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.417-430
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• 2003

A new method was developed to prepare microcapsules involving hydrophobic components. A totally new "silicone-resin-polypeptide" was used as the wall materials. The polypeptide was made by hydrolysis of collagen and silk protein and so on, and that was combined with silicone. This microcapsule was easily prepared from silicone-resin-polypeptide in water solution. The ratio of encapsulation in the microcapsule was not only high level as 90％, which had never been reached, but also the particle size could be controlled to obtain very small size (average particle size: 2${\mu}{\textrm}{m}$). Moreover, these microcapsules were resistant to high shearing forces and were stable over a long time period. This stable microcapsule was not crushed in pressure with finger spreading, so the core materials hardly touch the skin directly. Application in cosmetics by using microcapsule involving UV absorbents (2-ethylhexy1-4-methoxycinnamate (OMC) and 4-tert-butyl-4' -methoxydibenzoyl-methane (BMDBM)) was examined. It was possible to apply organic UV absorbents in water-rich formulations without any surfactant by using this microcapsule. This formulation demonstrated a good moisturizing and soft skin feel. Therefore, the microcapsule was applied to hair care products. As a result, the sunscreen hair lotion with microcapsule was able to prevent from damaging and decoloring of hair color by UV rays. As just, it was suggested that this microcapsules were be widely applied in cosmetics.cosmetics.

• Journal of Microbiology and Biotechnology
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• v.31 no.7
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• pp.933-941
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• 2021

Ginsenoside Rg4 is a rare ginsenoside that is naturally found in ginseng, and exhibits a wide range of biological activities including antioxidant and anti-inflammatory properties in several cell types. The purpose of this study was to use an in vivo model of hair follicle (HF)-mimic based on a human dermal papilla (DP) spheroid system prepared by three-dimensional (3D) culture and to investigate the effect of Rg4 on the hair-inductive properties of DP cells. Treatment of the DP spheroids with Rg4 (20 to 50 ㎍/ml) significantly increased the viability and size of the DP spheres in a dose-dependent manner. Rg4 also increased the mRNA and protein expression of DP signature genes that are related to hair growth including ALP, BMP2, and VCAN in the DP spheres. Analysis of the signaling molecules and luciferase reporter assays further revealed that Rg4 induces the activation of phosphoinositide 3-kinase (PI3K)/AKT and the inhibitory phosphorylation of GSK3β, which activates the WNT/β-catenin signaling pathway. These results correlated with not only the increased nuclear translocation of β-catenin following the treatment of the DP spheres with Rg4 but also the significant elevation of mRNA expression of the downstream target genes of the WNT/β-catenin pathway including WNT5A, β-catenin, and LEF1. In conclusion, these results demonstrated that ginsenoside Rg4 promotes the hair-inductive properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway in DP spheres, suggesting that Rg4 could be a potential natural therapy for hair growth.

• Prospectives of Industrial Chemistry
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• v.22 no.1
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• pp.12-22
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• 2019

탈모 인구의 증가로 국내 탈모 시장이 빠르게 팽창하고 있으며, 탈모 관련 산업이 성장기에 진입하였다. 탈모시장은 탈모관리제품, 기기, 관리실 및 의료 시술로 세분화되고 있으며 관련 신제품들이 개발되고 있지만 샴푸와 같은 화장품 시장의 규모가 가장 크게 자리 잡고 있는 상황이다. 세계 헤어케어 관련 화장품 시장은 중국의 탈모 관련 미용산업 시장규모가 매우 크며, 국내 기업들도 중국 탈모 시장에 선진출하기 위해 제품개발 및 마케팅을 강화하고 있다. 이러한 시장동향과 더불어 국내에서는 새로운 소재 개발과 함께 안전하고 기능성이 뛰어난 탈모방지 화장품의 요구가 확대되고 있는 추세이다. 따라서 본 기획에서는 현재 기능성 헤어케어 제품들의 시장분석과 동업계 현황, 5-Force 분석을 통한 경쟁상황, 수요전망 등에 대하여 소개하고, 향후 탈모방지 화장품시장의 발전 가능성과 향후 전략 방안을 제시하고자 한다.

• Textile Coloration and Finishing
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• v.24 no.1
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• pp.27-32
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• 2012

Generally, hair treatments by complementary actions to give a sense of activity are permanent setting, dyeing, and bleaching, etc. In this study, we investigated the wave formation ability and hair damage occuring in permanent setting and bleaching process. The wave formation ability was evaluated by the differences of length and curl diameter after permanent setting. And the hair damage was also evaluated by the protein release ability and SEM of hair. The bleached hair immediately after permanent setting treatment has better wave formation ability, but much more damaged than the bleached hair after rinsing thoroughly with warm water. It was considered that the chain of hair keratin broke down easily by the bleaching action in the existence of permanent setting agents.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2007.11a
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• pp.117-126
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• 2007

Cosmetics have mild activity on the human body, and intended to be used for cleaning, beautifying the human body, and also keeping healthy skin or hair, promoting attractiveness or altering the appearance. Functional cosmetics, in other words cosmeceuticals, are restricted for following functions: 1) Whiten the skin tone by preventing deposition of melanin pigmentation or lightening of the color of melanin of skin, 2) alleviate or improve wrinkles of the skin, and 3) protect the skin from the ultra violet rays from the sun. According to the functions of the functional cosmetics, skin whitening products, anti-wrinkle products, and suntan & sunscreen products are manufactured. In order to manufacture and import the functional cosmetics in Korea, the approval process in KFDA is necessary. The review process in KFDA is performed based on The Korea Food and Drug Administration Notification 2007-44, "The Regulation of Reviewing the Functional Cosmetics" (June 29, 2007). Only after the approval of KFDA, functional cosmetics are allowed to advertise to the consumers for their functionality.

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.4
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• pp.611-621
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• 2009

As fashion is a visual symbol that reflects age and culture, cosmetics and beauty are other products of fashion that move the time. A dominant designer of 20th century Chanel does not merely stand for a design innovation of fashion industry that created a vogue. With liberation from corsets that cruelly exaggerated and suppressed female body, meaning of style in modern fashion could be found not only in clothing but also in make-up and hair style. Simplest possible comfort was aimed for, and philosophical concepts of minimalism, modernism and dandyism were incorporated with clothing, cosmetics, perfume, make-up and hair style to establish aesthetical concept of total fashion. Chanel thought of cosmetics as an accessory with essential role and although her philosophy on cosmetics and beauty is not as well known as her clothing style, the authors believe that understanding such philosophy will become an important stepping stone for accurately understanding Chanel style. The purpose of this study is to firstly illuminate the idea that cosmetic beauty can be studied with artistic and philosophical background in addition to its functional side and to secondly investigate the reason why Chanel style is being loved by women with such durability over time and space and with what tempo fashion is connected with cosmetic beauty culture and develops. Third, by studying the ways in which characteristics of Chanel's fashion philosophy are expressed in cosmetics and beauty culture, this study aims to accurately understand Chanel's philosophy on cosmetics and beauty. The meaning of this study can be found by showing the evidence that globalization of Korean fashion beauty culture can be achieved only when cosmetics and beauty culture moves with an intimate connection to clothing culture.

• Textile Coloration and Finishing
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• v.24 no.3
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• pp.204-212
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• 2012

This study was used a thermogravimetric analyzer to determine thermal characteristics, a hair analysis system to examine morphological changes of wefts-human hair, poly vinyl chloride(PVC) and polyethylene terephthalate (PET)-used in manufacturing wigs. According to a flammability test on human hair and synthetic wefts for wigs, the best results were observed in human hair. According to a thermal test, PET was the best in terms of thermal stability. Also good tensile strength was observed as well. In a scanning electron microscope observation, no human hair scale layer was found because of chemical treatment. In the PVC sample, homogeneous unevenness was observed. Due to a lack of human hair supply and increase in its price, recently, PET weft has emerged as a great substitution for human hair. Because it can be curled using an electric curling device and is more efficient than the conventional non-flammable material PVC in terms of thermal resistance, it will become the next-generation weft for wigs.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.37 no.2
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• pp.37-57
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• 2024

Objectives : The purpose of this study is to evaluate the efficacy and safety of hair Ampoules with Malva Verticillata Seed Extract in alopecia patients. Methods : This 24-week clinical study enrolled 70 patients with Alopecia. A series of clinical examinations, subjects were evaluated at 0, 8, 16 and 24-week, counting of the number of hairs on the crown, and subject survey after using the Ampoules. Results : The clinical evaluation showed a significantly difference (p<0.05) after 24 weeks of product use compared to the baseline in the change in hair count in the treatment group compared to the control group within and between groups. It showed greater improvement in the treatment group than in the control group in hair count, hair thickness, and hair loss symptoms in the top of the head and forehead. No severe adverse events were observed during the clinical trial. Counclusions : This suggests that this hair ampoules containing Malva Verticillata Seed Extract could help prevent hair loss in alopecia patients without inducing side effects.

• Toxicological Research
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• v.35 no.2
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• pp.161-165
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• 2019

Cysteamine has been used in cosmetics as an antioxidant, a hair straightening agent, and a hair waving agent. However, recent studies indicate that cysteamine can act as an allergen to hairdressers. The objective of this study was to develop and validate a simple and effective reversed-phase high-performance liquid chromatography (RP-HPLC) method for the measurement of cysteamine and its dimer, cystamine. Sodium 1-heptanesulfonate (NaHpSO) was used as an ion-pairing agent to improve chromatographic performance. Separation was performed on a Gemini C18 column ($250mm{\times}4.6mm$, $5{\mu}m$ particle size) using a mobile phase composed of 85:15 (v/v) 4 mM NaHpSO in 0.1% phosphoric acid:acetonitrile. UV absorbance was monitored at 215 nm. The RP-HPLC method developed in this study was validated for specificity, linearity, limit of detection, limit of quantitation, precision, accuracy, and recovery. Cysteamine and cystamine were chromatographically resolved from other reducing agents such as thioglycolic acid and cysteine. Extraction using water and chloroform resulted in the recovery for cysteamine and cystamine ranging from 100.2-102.7% and 90.6-98.7%, respectively. This validated RP-HPLC method would be useful for quality control and monitoring of cysteamine and cystamine in cosmetics.