• Journal of Acupuncture Research
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• 제37권4호
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• pp.203-208
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• 2020

This literature review was designed to investigate the effects of the microneedle therapy system (MTS) on alopecia in experimental, and clinical studies. The MTS is acupuncture needling therapy delivered by a roller. A literature review of studies published before May 2020 was conducted using 9 online databases, and a total of 13 studies (4 in vivo studies and 9 clinical trials) were included. Most studies showed that the MTS was effective when used in combination with other treatments. In vivo studies reported an increased level of hair growth factors following treatment. Typically, 1.5 mm needles were used in the MTS treatment and photographic evaluation (by either camera or microscope) was reported in most studies. Oriental medicine research included 2 in vivo studies, which reported positive effects when combined with the MTS. There were no reported severe side effects. the MTS might be safe and has a drug delivery effect. Further studies need to be conducted regarding the frequency and needle length depending on the type of alopecia using Oriental and Western medicine.

• Journal of Ginseng Research
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• 제43권2호
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• pp.272-281
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• 2019

Background: Diabetic sensorineural damage is a complication of the sensory neural system, resulting from long-term hyperglycemia. Red ginseng (RG) has shown efficacy for treatment of various diseases, including diabetes mellitus; however, there is little research about its benefit for treating sensorineural damage. Therefore, we aim to evaluate RG efficacy in alloxan-induced diabetic neuromast (AIDN) zebrafish. Methods: In this study, we developed and validated an AIDN zebrafish model. To assess RG effectiveness, we observed morphological changes in live neuromast zebrafish. Also, zebrafish has been observed to have an ultrastructure of hair-cell cilia under scanning electron microscopy. Thus, we recorded these physiological traits to assess hair cell function. Finally, we confirmed that RG promoted neuromast recovery via nerve growth factor signaling pathway markers. Results: First, we established an AIDN zebrafish model. Using this model, we showed via live neuromast imaging that RG fostered recovery of sensorineural damage. Damaged hair cell cilia were recovered in AIDN zebrafish. Furthermore, RG rescued damaged hair cell function through cell membrane ion balance. Conclusion: Our data suggest that RG potentially facilitates recovery in AIDN zebrafish, and its mechanism seems to be promotion of the nerve growth factor pathway through increased expression of topomyosin receptor kinase A, transient receptor potential channel vanilloid subfamily type 1, and mitogen-activated protein kinase phosphorylation.

• 한방안이비인후피부과학회지
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• 제14권1호
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• pp.66-75
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• 2001

Acne is a chronic, inflammatory disorder that mainly affects teenagers and young adults. The disease has many causes, blocking hair follicle or sebaceous gland. Acne is not life threatening, but quality of a patient is compromised. Therefore, the patient needs an active treatment. With this in mind, I witnessed some noticeable improvement among the patients by prescribing Myunposan(面疱散). Here are the findings of my experience. 1. Out of acne patients who visited Oriental Medicine Hospital of Kyung-Won University(暻園大學校서울韓方病院) during September 2000 - December 2000, 8 patients whose prognosis is dramatic were subjects. 2. Myunposan(面疱散) deems effective in removing wind(祛風), unnecessary metabolite(祛痰), heat(淸熱), and draining pus(排膿), and preventing evil effects(解毒). 3. In the case of those 8 success stories as a result of taking Myunposan(面疱散), in the order of redness, pain, iching, and fever, symptoms were quick to disappear, and papula, pustula, etc got better albeit slower. 4. Depending on general symptoms, oriental medicine and acupuncture treatment on top of taking Myunposan(面疱散), symptoms were even quicker to go away and improved.

• 생약학회지
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• 제34권4호통권135호
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• pp.278-281
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• 2003

Cynanchi Wilfordii Radix has been used for the treatment of prematurely grey hair, bald and constipation and Polygoni Multiflori Radix has been used for the treatment of weakness, knee pain, premature greying, elevated serum cholesterol, coronary heart disease, naurasthenia and insominia. Pattern recognition for the analysis of Cynanchi Wilfordii Radix and Polygoni Multiflori Radix was conducted using HPLC method. Pattern of Cynanchi Wilfordii Radix and Polygoni Multiflori Radix was different and we distinguished two medicinal plants by HPLC.

• 한국임상수의학회지
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• 제17권2호
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• pp.499-501
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• 2000

Paraphilmosis, is a condition in which the extruded penis cannot be withdrawn back into the preputial cavity. In this study, the 2 dogs that showed prolonged erection. exposed penis from the sheath and hair surrounding the prepural orifice for several days, were ana1ysis of blood and urine ard carried out surgical treatment. In urinalysis, there were struvites, spermuria and bactera (streptococci) in urine. Firstly, these dogs were treated with non-surgical method, however severe necrosis of the Penis was developed form prolonged exposure and vascular compromise. Finally, partial penile amputation and preputial lengthening were performed and resulted in successful treatment.

• Pediatric Infection and Vaccine
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• 제31권1호
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• pp.122-129
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• 2024

Chediak-Higashi syndrome (CHS) is a rare haematological and immunodeficiency disorder that occurs in childhood leading to recurrent infections, bleeding tendencies and progressive neurological dysfunction. Partial oculocutaneous albinism occurs in almost all cases. The exact prevalence is unknown, and the disease is caused by over 70 identified mutations in the lysosomal trafficking regulator gene. The presence of a bright polychromatic appearance from hair shaft and abnormally large intracytoplasmic granules, especially within neutrophils and platelets in the bone marrow is highly suggestive. Treatment is largely supportive, and the only curative treatment is through an allogeneic hematopoietic stem cell transplant. Without transplant, most patients will enter an accelerated phase of hemophagocytic lymphohistiocytosis (HLH) which carries a high mortality rate. We present a young male with CHS who we had followed through and eventually developed a fulminant accelerated phase. We believe this is only the second reported case of CHS in Malaysia.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3593-3599
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• 2014

Background: Efficacy of childhood cancer treatment in low-income countries may be impacted by parents' and health-care providers' perspectives on chemotherapy-related side-effects. This study explores prevalence and severity of side-effects in childhood cancer, and compares health beliefs about side-effects between parents and health-care providers, and between nurses and doctors in Indonesia. Materials and Methods: Semi-structured questionnaires were filled in by 40 parents and 207 health-care providers in an academic hospital. Results: Parents exporessed a desire to receive more information about side-effects (98%) and worried about this aspect of treatment (90%), although side-effects were less severe than expected (66%). The most frequent was behavior alteration (98%) and the most severe was hair loss. Only 26% of parents consulted doctors about side-effects. More parents, compared to health-care providers, believed that medicines work better when side-effects are more severe (p<0.001), and accepted severe side-effects (p=0.021). More health-care providers, compared to parents, believed that chemotherapy can be stopped or the dosage altered when there are side-effects (p=0.011). More nurses, compared to doctors, stated that side-effects were unbearable (p=0.004) and made them doubt efficacy of treatment (p<0.001). Conclusions: Behavior alteration is the most frequent and hair loss the most severe side-effect. Apparent discrepancies in health beliefs about side-effects exist between parents and health-care providers. A sustainable parental education program about side-effects is recommended. Health-care providers need to update and improve their knowledge and communication skills in order to give appropriate information. Suchmeasures may improve outcome of childhood cancer treatment in low-income countries, where adherence to therapy is a major issue.

• 한국동물위생학회지
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• 제40권2호
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• pp.143-147
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• 2017

A Korean domestic short hair (1-year-old, male) presented with 2 to 3 weeks of seizures, aggressive behavior, vomiting, anorexia, and lethargy. The frequency of seizure had gradually increased from once a week to once every 3 hours. Physical and neurologic examination, diagnostic screening tests, including complete blood count (CBC), serum chemistry, electrolyte, coagulation test, X-ray, ultrasonography, and urinalysis were performed. Feline Leukemia Virus (FeLV), Feline Immunodeficiency Virus (FIV) and Toxoplasma spp. All tested negative, but the Feline Corona Virus (FCoV) kit revealed a positive result. To determine the exact diagnosis, magnetic resonance imaging (MRI) was performed but yielded no specific findings. The patient was then diagnosed with idiopathic epilepsy and treatment of phenobarbital was initiated. A month's treatment with phenobarbital proved ineffective as symptoms worsened. Zonisamide was then selected as an additional anticonvulsant. After adding zonisamide, symptoms improved, and seizures abated for 15 months. This is the first case report in South Korea describing the use of phenobarbital and zonisamide in the treatment of a cat with idiopathic epilepsy.

• 대한간호학회지
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• 제33권1호
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• pp.71-78
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• 2003

Purpose: The study was done to identify the relationship of treatment side effects, family support, and quality of life in patients with cancer, and factors influencing quality of life. Method: A convenience sample of 106 patients who were receiving cancer treatment at W hospital were interviewed using the Side Effects scale by Hur, Family Support scale by Kang, and QOL scale by Ro. Result: Results indicate that women experienced more severe side effects than men. There was a negative relationship between side effects and quality of life, and a positive relationship between family support and quality of life. The most bothersome side effects were changes in taste and appetite, followed by general weakness and fatigue. Side effects such as loss of hair, nausea, dizziness, numbness, pins and needles in fingers and toes, and dry mouth were also experienced. General weakness and family support were analysed as to whether they were factors influencing quality of life. Conclusion: The results revealed that relieving general weakness should be given high priority in nursing interventions for patients undergoing cancer treatment. In addition, nursing programs should be developed that can reinforce family support.

• 혜화의학회지
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• 제24권2호
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• pp.25-34
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• 2016

Objectives : Historical study on application of Kyungohkgo, one of the most popular tonic medicine, and suggestion of modernistic method through it Methods : Investigated effect and its range of Kyungohkgo in original texts of Korean medicine, and researched studies on medical action and treatment effect of Kyungohkgo nowaday. Results : Kyungohkgo has "replenish essence and marrow(補精益髓)" as a major effect, and various original text suggested that Kyungohkgo can be used as antioxidant tonic medicine, treatment of respiratory disease like tuberculosis and medicine for bone disease controling hormone. Several research about these subjects has been progressed recently. However, the most of these researches is not an in-depth study about virtues in original texts, but deduced from effects of Kyungohkgo, and there are some studies experimented with Kyungohkgo that has not followed its own formula. Conclusions : It is required to discuss new application based on understanding effect and is range of Kyungohkgo. It could be thought that using for skin disease based on t theory of "lung presides skin and hair", chronic pulmonary disease based on treatment of cough(咳嗽), and disease of uterine and bone based on "replenish essence and marrow(補精益髓)".