• Title/Summary/Keyword: Haemoglobin

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Bleeding Efficiency and Meat Oxidative Stability and Microbiological Quality of New Zealand White Rabbits Subjected to Halal Slaughter without Stunning and Gas Stun-killing

  • Nakyinsige, K.;Fatimah, A.B.;Aghwan, Z.A.;Zulkifli, I.;Goh, Y.M.;Sazili, A.Q.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.406-413
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    • 2014
  • A study was conducted to compare the effect of halal slaughter without stunning and gas stun killing followed by bleeding on residual blood content and storage stability of rabbit meat. Eighty male New Zealand white rabbits were divided into two groups of 40 animals each and subjected to either halal slaughter without stunning (HS) or gas stun-kill (GK). The volume of blood lost during exsanguination was measured. Residual blood was further quantified by determination of haemoglobin content in Longissimus lumborum (LL) muscle. Storage stability of the meat was evaluated by microbiological analysis and measuring lipid oxidation in terms of thiobarbituric acid reactive substances (TBARS). HS resulted in significantly higher blood loss than GK. HS had significantly lower residual haemoglobin in LL muscle compared to GK. Slaughter method had no effect on rabbit meat lipid oxidation at 0, 1, and 3 d postmortem. However, at 5 and 8 days of storage at $4^{\circ}C$, significant differences (p<0.05) were found, with meat from the GK group exhibiting significantly higher levels of MDA than that from HS. At day 3, greater growth of Pseudomonas aeroginosa and E. coli were observed in the GK group (p<0.05) with B. thermosphacta and total aerobic counts remained unaffected by slaughter method. At days 5 and 7 postmortem, bacterial counts for all tested microbes were affected by slaughter method, with GK exhibiting significantly higher growth than HS. It can be concluded that slaughter method can affect keeping quality of rabbit meat, and HS may be a favourable option compared to GK due to high bleed out.

A Randomized Comparative Study of Unani Formulations in Abnormal Uterine Bleeding due to Endometrial Hyperplasia

  • Abothu Suhasini;Wasia Naveed;Arshiya sultana;Shahzadi Sultana
    • CELLMED
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    • v.13 no.14
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    • pp.19.1-19.16
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    • 2023
  • Objectives: To compare the efficacy of polyherbal Unani formulations in heavy menstrual bleeding due to endometrial hyperplasia. Methodology: A prospective, randomized comparative trial was conducted at Govt. Nizamia Tibbi College. Group A (n=20) received Itrifal Aftimoon 5g orally BID from menstruation day 3 to day 21 plus suprapubic Marham Dakhilyun application and per vaginally Marham Dakhilyun (5g) and Roghan Gul (10ml) application from menstruation day 5 to day 14. Group B (n=20) received Gulnar Farsi (2g), Phitakri Biryan (0.25g), Dammul Aqwain (0.25g), and Geru (2g), 2.5g powder orally BID, menstruation day 3 for 20 days plus Douche Bargh Sambhalu then Ḥamūl of Safuf Mazu (2g), Kalijiri (2g) and Roghan Gul (10ml) from menstruation day 3 to day 12 for 3 consecutive cycles. The primary outcome was pelvic ultrasound findings of endometrial thickness. The secondary outcome measures were improvement in haemoglobin percentage, change in menstrual flow and menstrual pattern. The level of significance was 5%. Results and conclusion: The intragroup comparison showed that the mean endometrial thickness at baseline and after treatment in groups A and B was extremely significantly different (P<0.0001). The intragroup comparison showed the mean haemoglobin percent at baseline and after treatment in group, A was significantly different (P<0.0001). After treatment, 50% and 60% of participants had normal duration and menstrual blood loss after treatment from baseline in Groups A and B respectively. However, further, phase II and III randomized standard controlled trials in larger samples are recommended to assess the efficacy of these group medicines.

A Study on Antitoxic Effects of Pine Leaf Extracts against Cadmium Toxicity in Rats (송엽 추출물을 이용한 카드뮴 독성의 해독에 관한 연구)

  • 이종섭;박경옥
    • Journal of Environmental Health Sciences
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    • v.22 no.3
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    • pp.88-97
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    • 1996
  • This study was conducted to investigate the antitoxic effects of Pine Leaf extracts against cadmium toxicity. The experimental rats were divided into 5 groups, such as control group cadmium alone treatment group and simultaneous treatment groups of cadmium and three doses of Pine Leaf extracts. Each group was administered with different dose of Pine Leaf extracts such as 0.5 mg, 2.5 mg, 5.0 mg/kg wet weight in pallets for 12 weeks. Cadmium Chloride($CdCl_2$) was administered by 4 mg/kg body weight. The results were summarized as follows: The simultaneous administration of cadmium and Pine Leaf significantly more decreased cadmium concentration in liver tissues compared to the administration of cadmium only. When blood were measured, no significantly difference in haemoglobin, haematocrit, erythrocyte values compared to the administration of cadmium only, but RBC significantly more increased. The simultaneous administration of cadmium and Pine Leaf more no sigmificantly difference metallothionein concentration in liver than the administration of cadmium only. There were showed the histopathological slight changes in the liver and kidney tissues of rats.

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A Study on the Effects of Radix Menispermi Extracts Against Cadmium Chloride Sub-chronic Toxicity in Rats (카드뮴 중독에 대한 산두근 추출액의 해독효과에 관한 연구)

  • 이종섭;박경옥;이정미
    • Toxicological Research
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    • v.12 no.1
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    • pp.59-68
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    • 1996
  • This study was conducted to investigate the antitoxic effects of Radix Menispermi extracts against cadmium toxicity. The experimental rats were divided into 5 groups such as control group, cadmium alone treatment group and simultaneous treatment groups of cadmium and three doses of Radix Menispermi extracts. Each group was administered with different dose of Radix Menispermi extracts such as 0.55 mg, 1.10 mg, 1.65 mg/kg wet weight in pallets for 12 weeks. Cadmium Chloride $(CdCl_2)$ was administered by 4 mg/kg body weight. The results were summarized as follows: 1. The simultaneous administration of cadmium and Radix Menispermi significantly more decreased cadmium concentration in liver tissues compared to the administration of cadmium only (P < 0.05). 2. When blood were measured, no significantly difference in haemoglobin, haematocrit, erythrocyte values compared to the administration of cadmium only. 3. The simultaneous administration of cadmium and Radix Menispermi more increased metallothionein concentration in liver than the administration of cadmium only (P < 0.05). 4. There were the histopathological slight changes in the liver and kidney tissues of rats.

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Synthesis of some pyridinethione derivatives and their biological activity

  • Miky, Jehane A.A.;Zahkoug, Samir A.M.
    • Natural Product Sciences
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    • v.3 no.2
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    • pp.89-99
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    • 1997
  • Aminolysis, hydrazinolysis and alkylation of 4-methoxy and 4,9-dimethoxy-6-cyano-7-thione-5-methyl-7H furo [3,2-g] [1] benzopyridine (1 a-b) yielded 7N-substituted furobenzopyridine derivatives (2 a-e or the possible isomers 3 a-e and 4 a-b), (5 a,b and 6 a,b) and the ester (8 a,b). Hydrolysis of (la) with acetic acid gave the corresponding pyridone derivatives (7). Furobenzopyridinyl-7-thioacetyl hydrazide (9 a,b) have been prepared via alkylation of furobenzopyridine thione (1 a-b) with ethyl chloroacetate followed by condensation with hydrazine hydrate. Schiff base (11) was prepared by reacting (9a) with p. N,N-dimethyl aminobenzaldehyde in boiling ethanol. Treatment of (8a) with anthranilic acid gave the corresponding 7-substituted-4H-3,1-benzoxazine-4-one (10). We found that compound (11) increased bleeding, coagulating time, the total count of white blood cells, blood glucose level (cause hyperglycemia), enzymes (GOT, GPT) activities, concentration of urea and creatinine. On the other hand it decreased red blood cells number, haemoglobin content and haematocrite value.

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Studies on Serum Micro-mineral, Hormone and Vitamin Profile and Its Effect on Production and Therapeutic Management of Buffaloes in Haryana State of India

  • Sharma, M.C.;Raju, S.;Joshi, C.;Kaur, H.;Varshney, V.P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.4
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    • pp.519-528
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    • 2003
  • A survey was conducted in certain parts of Haryana to record the prevalence of micro mineral deficiency in buffaloes. The prevalence of soil Cu, Co, Zn and Fe deficiency was 55.26%, 6.9%, 59.12% and 7.89% respectively. While that of fodder Cu, Co, Zn and Fe was 60.64%, 6.7%, 61.22% and 11.37% respectively. The overall prevalence of serum Cu, Co, Zn and Fe deficiency in Haryana was 59.2%, 19.1%, 59.2% and 19.9% respectively. The correlation co-efficient of Cu, Co, Zn and Fe in soil, fodder and serum was significant in most of the cases the values were above 0.8. Blood examination revealed significant decrease in haemoglobin and TEC level. However, no variation in level of TLC were observed in mineral deficient buffaloes. In micro mineral deficiency, thyroid hormone (T3 and T4) levels were decreased in buffaloes. Marginally lower concentration of vitamin A and E were observed in mineral deficient buffaloes in Haryana. The highest deficiency of micro minerals was 61.76% in copper at Ambala followed by 65.86% in zinc at Rhotak. For therapeutic studies a mineral mixture was prepared according to defiency obtained and fed to three groups of animals. Observation was recorded on 0, 15, 30, 45 and 60 days. Group A consist of normal healthy animals and group B mineral deficient animal untreated and group C mineral deficient animal, treated with prepared mineral mixture. 25 gram of mineral mixture was fed daily along with normal ration. There was increase in body weight, milk yield, haemoglobin concentration and total erythrocyte level in group C animals when compared to group B animals. The milk yield in group C animals increased to 6.970${\pm}$0.41 after 60th day of supplement in comparison to 0 day where it was 5.910${\pm}$0.37, similarly the body wt. of group C animals increased from 129.42${\pm}$01.13 (at 0 day) to 159.31${\pm}$03.61 at 60th day of treatment.

A Case Report of Diabetic Hyperlipidemia in a Patient with Cerebral Infarction Treated with Ojeok-san (뇌경색 환자의 당뇨병성 고지혈증에 대한 오적산가감방(五積散加減方) 호전 1례)

  • Han, Seung-Hea;Jeong, Byeong-Ju;Woo, Sung-Ho;Kim, Byung-Chul;Kim, Yong-Ho;Seo, Ho-Seok;Hwang, Gyu-Dong;Cho, Cheol-Jun;Nam, Hyo-Ick;Kim, Jin-Won
    • The Journal of Internal Korean Medicine
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    • v.26 no.1
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    • pp.275-280
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    • 2005
  • Hyperlipidemia is one of the major factors causing the atherosclerosis of coronary arteries and well-documented modifiable risk factors of stroke, especially of the ischemic type. For Insulin-Dependent Diabetes Mellitus sufferers, if blood sugar is appropriately maintained, lipid and lipoprotein are normal, but if blood sugar is inappropriately maintained or clinical Diabetic nephropathy induces metabolic disorder of lipid, then Total cholesterol, low density lipoprotein cholesterol, triglyceride and very low density lipoprotein cholesterol levels go up and high density lipoprotein levels go down. The purpose of this study is to evaluate the effect of treatment with Ojeok-san and to observe the changes in Fasting Blood Sugar(FBS), 2 Hours Postprandial Blood Sugar(PP2h), Haemoglobin A1c(HbA1c), Total Cholesterol(T-Chol) and Triglyceride(TG). After the treatment, Fasting Blood Sugar decreased from 149mg/dl to 89mg/dl. 2 Hours Postprandial Blood Sugar decreased from l85mg/dl to 110mg/dl. Haemoglobin A1c decreased from 6.3% to 5.7%. Total Cholesterol decreased from 268mg/dl to 217mg/dl. And Triglyceride decreased from 438mg/dl to 265mg/dl. These results support a role for oriental medical therapy in treating Diabetic Hyperlipidemia. Further case studies of herbal treatment of this ailment are needed.

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Design of an $SpO_2$ Transmission Agent based on ISO/IEEE 11073 Standard Protocol (ISO/IEEE 11073 표준 프로토콜 기반의 산소포화도 전송 에이전트 설계)

  • Pak, Ju-Geon;Im, Sung-Hyun;Park, Kee-Hyun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.10a
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    • pp.462-465
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    • 2011
  • A pulse oximeter is a device which provides non-invasive estimate of percentage oxygen saturation of haemoglobin (SpO2). Due to the limitations of resources of personal health devices (PHDs) including pulse oximeters, they generally transmit the estimated data to a remote monitoring server through a close manager (e.g. mobile device or PC). Therefore, communication protocols between PHDs and a manager is an important research topic in terms of interoperability. In this paper, we present design results of an SpO2 transmission agent based on the ISO/IEEE 11073 (X73) protocol. The protocol is an international standard for PHDs. The agent is an embedded program which generates X73 messages from the estimated pulse rates and SpO2, and transmits the messages to a close manager. The agent consists of a Session, Message and Memory Handler. The Session Handler manages a communication session with the manager, and the Message Handler generates and analyzes the exchanged messages according to the X73 protocol. The Memory Handler extracts pulse rates and SpO2s which are stored in a memory of the pulse oximeter. The SpO2 transmission agent allows pulse oximeters to communicate with managers based on x73 standard. Consequently, the interoperability between the pulse oximeters and the managers is guaranteed.

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A Survey of Blood Glucose Testing, Medication, Diet, and Exercise Adherence in Korean Patients with Type2 Diabetes (당뇨병환자의 자가혈당검사, 약물, 식이 및 운동 치료지시이행)

  • Kim Hee-Seung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.10 no.2
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    • pp.181-186
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    • 2003
  • Purpose: The purpose of this study was to investigate the adherence to diabetes control recommendations (blood glucose testing, medication, diet, exercise) in patients with type 2 diabetes at home and to analyse the correlation between adherence and blood glucose level. Method: Participants, numbering 214, were recruited from the endocrinology outpatient department of a tertiary care hospital in an urban city. The data were collected by a self report adherence questionnaire. Glycosylated haemoglobin (HbA1c) was determined by the high-performance liquid chromatography technique and fasting blood glucose was analyzed by the glucose oxidase method. Result: Medication adherence was higher than diet or exercise adherence. The frequency of blood glucose testing was lower for middle school graduates than college graduates. Diet adherence was significantly lower for participants who were obese, who did not have a spouse, and who had hyperglycemia. Medication and diet adherence were negatively correlated with HbA1c. Conclusion: A diet education program should be developed for patients with type 2 diabetes who are obese, who do not have a spouse, and who have hyperglycemia.

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BLOOD BIOCHEMICAL PROFILE AND HISTOPATHOLOGY OF VITAL ORGANS IN RABBITS FED ON PROCESSED NEEM (Azadirachta indica) KERNEL MEAL INCORPORATED DIETS

  • Gowda, S.K.;Katiyar, R.C.;Sharma, A.K.;Sastry, V.R.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.9 no.4
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    • pp.471-476
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    • 1996
  • Blood biochemical and histopathological changes in vital organs of rabbits were studied after 19 wk of feeding composite diets (75 concentrate : 25 roughage) incorporating either urea (2%, wt/wt) ammoniated or alkali (1.5%, wt/wt) treated neem kernel meal (NKM) replacing peanut meal protein of control diet by either 50 or 100%. The blood biochemical constituents (Haemoglobin, Alanine amino transferase, Aspartate amino transferase, Total protein, Blood urea nitrogen &Cholesterol) in rabbits fed on processed NKM diet at either levels, were comparable to the values of thos on control diet except a lowered (p < 0.05) blood glucose concentration in processed NKM fed rabbits as compared to that in control diet fed ones. Histological examination revealed increased goblet cell activity, stunting of jejunal villi, mild tubular degeneration in kidney and hepatic fibro-cellular reaction in rabbits fed on urea ammoniated and alkali treated NKM diets with less marked changes in the latter. Testicular changes with variable degree of disorganization and vacuolation of spermatogonial cells were noticed in rabbits fed higher levels of urea-ammoniated and alkali treated NKM. Thus, alkali treatment and urea-ammoniation were effective in detoxification of meal, but the processing technology is to be further perfected to prevent cumulative effect of residual neem bitters in long term feeding.