• Interdisciplinary Bio Central
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• v.2 no.3
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• pp.7.1-7.3
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• 2010

Stroke, also called an attack on the brain, is a complex disease that results from the interaction of many genetic and environmental factors. StrokePortal is a comprehensive resource for information on stroke that integrates and provides essential findings regarding stroke pathology, diagnostics, and treatments, based on Oriental and Western medicine. The stroke information was collected from various sources, such as journal articles, books, websites, and news stories, and it was refined, classified, and stored into a relational database system by automatic classification and manual curation. To provide the stored information effectively to users, a specialized retrieval system, based on web interfaces, was implemented. StrokePortal provides cutting-edge information to experts; interested people, including patients and their families; and investigators to broaden their knowledge of effective treatments for patients and offer many preventive measures. It provides a specialized feature with which users can upload their information and opinions to StrokePortal, which will enrich and mature the content even further. StrokePortal is freely accessible at http://genomics.kribb.re.kr/StrokePortal/.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.11c
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• pp.1835-1838
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• 2002

컴퓨터의 초소형화 및 무선 통신의 범용화에 따라 모바일 환경이 급격히 발전하고 있다. 이동이 가능한 모바일 환경에서 위치와 관련된 작업을 위해 사용되는 공간 데이터를 제공하기 위한 서비스가 필요하다. 본 논문에서는 모바일 환경에서 무선 인터넷을 통해 공간 데이터를 획득할 수 있는 웹 피쳐서버(Web Feature Server)의 개발에 대해 설명한다. 웹 피쳐 서버에 대한 국제 표준은 OGC(Open GIS Consortium)에서 개발중이며 본 논문에서는 1.0.0 버전을 기반으로 모바일 환경을 위해 확장된 질의를 정의하여 처리한다. 웹 피쳐 서버는 크게 질의 관리자, 데이터 관리자, 인덱스 관리자로 구분되며 각각은 컴포넌트로 구현된다. 질의 관리자는 HTTP GET 방식을 통해 전달된 사용자의 요구를 분석한다. 데이터 관리자는 메모리 및 디스크에 저장된 공간 데이터에 접근하는 역할을 담당한다. 인덱스 관리자는 사용자의 질의에 맞는 공간 데이터를 효율적으로 선별하여 신속한 서비스를 제공한다. 웹 피쳐 서버가 제공하는 공간 데이터를 시험하기 위한 클라이언트로는 GML(Geography Markup Language)을 출력하는 컴포넌트를 개발한다.

• Journal of Korean Academy of Nursing
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• v.37 no.1
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• pp.14-25
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• 2007

Purpose: A user centered web-based mental health management system may be particularly useful in Korea where there is widespread diffusion of personal computers and internet connectivity. The purpose of this paper was to describe the development of a web-based system for mental health management in adolescents using principals of a user centered design. Method: Our design process includes five distinct phases: needs assessment, analysis, design, development/testing/revision, and application release. Results: Web content includes an introduction, information about mental health management in adolescents, self-assessment and guidance, interventions for improving mental health, directory of self-help groups, and counseling and additional community resources. The web site was released using the URL: http://www.baejy.com/youth. Conclusion: The end result was a web based mental health management system for adolescents with a high degree of usability. The author believes that web-based mental health interventions in the future have true potential in helping Koreans who are suffering, or at risk, for mental health problems, particularly because of the stigma related to psychiatric therapy in Korea.

• The Korean Journal of Emergency Medical Services
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• v.6 no.1
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• pp.65-75
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• 2002

This study was designed to develop e-Learning multimedia contents to provide the first aid rescuer with the basic resuscitation, members of the public, corporations and any other institutions who wish to learn this skills. It is carried out from October to December in 2001. This program was constructed on the basic of the network-instructional system Design model, this model has severalprogressive steps, which includes the planning, analysis of the contents, development of the contents, instructional design, development of web-based and multimedia, pilot test, implement, and evaluation. The URL of this site is http://www.cyber.hc.ac.kr named as the cyber education program for the basic resuscitatingskill. This contents consisted of 8 chapters providing as follows : Introduction, anatomy and physiology of heart-ling, Adult Cardio-Pulmonary Resuscitation, Adult Foregin-body Air-Obstruction, Child Cardio-Pulmonary Resuscitation, Child Foregin-body Air-Obstruction, Infant Cardio-Pulmonary Resuscitation, Infant Foregin-body Air-Obstruction. To make the learning more interesting, as much animation and videos were integrated. In conclusion, this e-Learning multimedia contents will be useful for student as well as members of the public. It significantly increases the chances of saving the life of person who has collapsed.

• Research in Community and Public Health Nursing
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• v.15 no.1
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• pp.29-35
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• 2004

Purpose: The purpose of this study was to investigate the computer input frequency of blood glucose self testing in type2 diabetic patients, for three months. Method: 39 participants were recruited from the endocrinology outpatient department of a tertiary care hospital in an urban city. The computer input frequencies were measured by patients' log in and input of http://www.biodang.com. Glycosylated haemoglobin was determined by a high performance liquid chromatography technique and fasting blood glucose was analyzed by the glucose oxidase method. Diabetes knowledge was measured by a 19 item diabetes knowledge test. Results: The computer input frequency of before breakfast blood glucose was 33.5 for three months. The total blood glucose input frequency tended to be lower in female, aged patients, middle school graduates, those who have no spouse and job, those who have no insulin treatment, obese subjects, and hyperglycemia patients, than in their counterparts. The diabetic knowledge was positively correlated with the computer input frequency of blood glucose self testing. Conclusion: An educational program should be developed to increase the computer input frequency of blood glucose self testing in type2 diabetic patients.

• Child Health Nursing Research
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• v.12 no.2
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• pp.233-243
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• 2006

Purpose: This study was aimed to develop a WBI(Web Based Instruction) program on safety for 6th grades of elementary school students and to test the effects of it. Method: The web site is http://www.safeschool.co.kr. The effect of it was tested from Mar 24, to Apr 30, 2003. The subjects were 150 students. Data were analyzed with descriptive statistics, and $x^2$ test, t-test, and repeated measure ANOVA. Result: In the knowledge of the safety precaution, the preliminary test was mean 17.8, immediate post-test was mean 20.9 and 4 weeks post-test was mean 20.9, there were significant differences statistically among three points of time. In the attitude of the safety precaution, the preliminary test was mean 75.1, the immediate post-test was mean 80.8 and 4 weeks post-test was mean 80.4, which showed significant difference statistically among three points of time. For the motive of learning to the safety precaution, it was significantly higher statistically in the WBI. As a result, the WBI group had totally longer effects on knowledge, attitude and motivation of the safety accident prevention than the textbook-based instruction. Conclusion: WBI program be used in each class to provide more effective safety instruction.

• Genomics & Informatics
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• v.6 no.2
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• pp.57-63
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• 2008

The Korean HapMap Project has been carried out for the last 5 years since it started in June, 2003. The project generated data for a sum of 1,764,000 Korean SNPs and formally registered the data to the dbSNP of NCBI (The dbSNP website. 2008). We have developed a series of software programs for association studies as well as for the comparison and analysis of Korean HapMap data with four other populations (CEPH, Yoruba, Han Chinese, and Japanese populations). The KHapmap Browser was developed and integrated to provide haplotype retrieval and comparative study tools of human ethnicities for comprehensive disease association studies (http://www.khapmap.org). On that basis, GBrowse was adopted in the KHapmap Browser for inherent Korean genetic data, and a provision of extended services was pledged with the distributed sequence annotation system (DAS). The dynamic linking service of the KHapmap Browser to other tools in our intranetwork environment provides many enhanced functions over GBrowse without DAS. KHapmap Browser is expected to be an invaluable tool for the study of Korean and international Hapmap data.

• CELLMED
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• v.2 no.2
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• pp.18.1-18.16
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• 2012

An oncology-specific database called OncoRx (http://bit.ly/cancerRx) was previously set up in cyberspace to aid clinicians in identifying interactions of anticancer drugs (ACDs) and chemotherapy regimens with traditional Chinese medicines (TCMs) and complementary and alternative medicines (CAMs). Since then, users have requested the drug-CAM interactions (DCIs) of 5 specific CAMs (cranberry, melatonin, co-enzyme Q10, huachansu, reishi mushroom) to be updated in the database. Pharmacokinetic properties (metabolism, enzyme induction/inhibition, elimination), TCM properties and DCIs of each CAM were collated with 117 ACDs using 9 hardcopy compendia and online databases as resources. Additionally, individual ACDs and CAMs were used as keywords for PubMed searches in combination with the terms 'anticancer drugs', 'drug interactions', 'herb-drug/drug-herb interactions', 'pharmacokinetic interactions' and 'pharmacodynamic interactions'. DCI parameters consisted of interaction effects, evidence summaries, proposed management plans and alternative non-interacting CAMs, together with relevant citations and update dates of the DCIs. OncoRx is also used as a case to introduce the "Four Pharmaco-cybernetic Maxims" of quality, quantity, relationship and manner to developers of digital healthcare tools. Its role in Hayne's "5S" hierarchy of research evidence is also presented. OncoRx is meant to complement existing DCI resources for clinicians and alternative medicine practitioners as an additional drug information resource that provides evidence-based DCI information for ACD-CAM interactions.

• BMB Reports
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• v.46 no.8
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• pp.416-421
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• 2013

Genome-wide association studies (GWAS) have become popular as an approach for the identification of large numbers of phenotype-associated variants. However, differences in genetic architecture and environmental factors mean that the effect of variants can vary across populations. Understanding population genetic diversity is valuable for the investigation of possible population specific and independent effects of variants. EvoSNP-DB aims to provide information regarding genetic diversity among East Asian populations, including Chinese, Japanese, and Korean. Non-redundant SNPs (1.6 million) were genotyped in 54 Korean trios (162 samples) and were compared with 4 million SNPs from HapMap phase II populations. EvoSNP-DB provides two user interfaces for data query and visualization, and integrates scores of genetic diversity (Fst and VarLD) at the level of SNPs, genes, and chromosome regions. EvoSNP-DB is a web-based application that allows users to navigate and visualize measurements of population genetic differences in an interactive manner, and is available online at [http://biomi.cdc.go.kr/EvoSNP/].

• Journal of Microbiology and Biotechnology
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• v.16 no.2
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• pp.178-183
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• 2006

Microbes are one of the most important bioresources in bioindustry and provide high economic values. Although there are currently about 6,000 bacterial species with validly published names, microbiologists generally assume that the number may account for less than 1% of the bacterial species present on Earth. To discover the remaining species, studies of metagenomes, metabolomes, and proteomes related to microbes have recently been carried out in various fields. We have constructed an information system that integrates various data on microbial resources and manages bioinformation to support efficient research of microorganisms. We have designated this system 'Bio-Meta Information System (Bio-MIS).' Bio-MIS consists of an integrated microbial resource database, a microbial resource input system, an integrated microbial resource search engine, a microbial resource online distribution system, a portal service, and management via the Internet. In the future, this system is expected to be connected with various public databases. We plan to implement useful bioinformatics software for analyzing microbial genome resources. The Web site is accessible at http://biomis.probionic.com.