• 제목/요약/키워드: HTR-PM

검색결과 14건 처리시간 0.023초

HTGR PROJECTS IN CHINA

  • Wu, Zongxin;Yu, Suyuan
    • Nuclear Engineering and Technology
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    • 제39권2호
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    • pp.103-110
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    • 2007
  • The High Temperature Gas-cooled Reactor (HTGR) possesses inherent safety features and is recognized as a representative advanced nuclear system for the future. Based on the success of the HTR-10, the long-time operation test and safety demonstration tests were carried out. The long-time operation test verifies that the operation procedure and control method are appropriate for the HTR-10 and the safety demonstration test shows that the HTR-10 possesses inherent safety features with a great margin. Meanwhile, two new projects have been recently launched to further develop HTGR technology. One is a prototype modular plant, denoted as HTR-PM, to demonstrate the commercial capability of the HTGR power plant. The HTR-PM is designed as $2{\times}250$ MWt, pebble bed core with a steam turbine generator that serves as an energy conversion system. The other is a gas turbine generator system coupled with the HTR-10, denoted as HTR-10GT, built to demonstrate the feasibility of the HTGR gas turbine technology. The gas turbine generator system is designed in a single shaft configuration supported by active magnetic bearings (AMB). The HTR-10GT project is now in the stage of engineering design and component fabrication. R&D on the helium turbocompressor, a key component, and the key technology of AMB are in progress.

Structural safety reliability of concrete buildings of HTR-PM in accidental double-ended break of hot gas ducts

  • Guo, Quanquan;Wang, Shaoxu;Chen, Shenggang;Sun, Yunlong
    • Nuclear Engineering and Technology
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    • 제52권5호
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    • pp.1051-1065
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    • 2020
  • Safety analysis of nuclear power plant (NPP) especially in accident conditions is a basic and necessary issue for applications and commercialization of reactors. Many previous researches and development works have been conducted. However, most achievements focused on the safety reliability of primary pressure system vessels. Few literatures studied the structural safety of huge concrete structures surrounding primary pressure system, especially for the fourth generation NPP which allows existing of through cracks. In this paper, structural safety reliability of concrete structures of HTR-PM in accidental double-ended break of hot gas ducts was studied by Exceedance Probability Method. It was calculated by Monte Carlo approaches applying numerical simulations by Abaqus. Damage parameters were proposed and used to define the property of concrete, which can perfectly describe the crack state of concrete structures. Calculation results indicated that functional failure determined by deterministic safety analysis was decided by the crack resistance capability of containment buildings, whereas the bearing capacity of concrete structures possess a high safety margin. The failure probability of concrete structures during an accident of double-ended break of hot gas ducts will be 31.18%. Adding the consideration the contingency occurrence probability of the accident, probability of functional failure is sufficiently low.

The Association between the T102C Polymorphism of the HTR2A Serotonin Receptor Gene and HDL Cholesterol Level in Koreans

  • Choi, Jin-Ho;Zhang, Shu-Ying;Park, Kyung-Woo;Cho, Young-Seok;Oh, Byung-Hee;Lee, Myoung-Mook;Park, Young-Bae;Kim, Hyo-Soo
    • BMB Reports
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    • 제38권2호
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    • pp.238-242
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    • 2005
  • 5-HT2A is one of major serotonin receptor that is involved in the action of serotonin-targeting drugs. Previous clinical studies have shown an unexpected association between lower cholesterol level and psychiatric diseases, in which T102C polymorphism of HTR2A, gene of 5-HT2A serotonin receptor, might be involved. Therefore, we hypothesized a potential association between lower cholesterol level and T102C polymorphism. The effect of the T102C polymorphism on the serum lipid profiles of 646 subjects without specific psychiatric disease was investigated. Genotype was determined by polymerase chain reaction and restriction fragment length polymorphism analysis. There were significantly lower levels of total cholesterol ($193.6{\pm}35.0$ versus $202.1{\pm}45.5\;mg/dl$, p = 0.016) and HDL-cholesterol ($42.7{\pm}11.6$ versus $46.3{\pm}12.7\;mg/dl$, p = 0.004) in CC genotype than non-CC genotypes. Moreover, multivariate analysis showed that the CC genotype is a strong predictor of a lower HDL-cholesterol level (p < 0.001). In conclusion, this study shows that the CC genotype of the HTR2A gene is related to lower HDL-cholesterol level in Koreans. This is the first demonstration showing the potential genetic relationship between the serotonin receptor gene polymorphism and the HDL-cholesterol level.

강원도 화천지역에 거주하는 40대 이상 주민의 혈청지질 농도 및 이와 관련된 요인 분석 (A Study on the Concentration of Serum Lipids and Its Related Factors of Persons Over 40 Years Old in Whachon Area, Kang-Won Do)

  • 이정선
    • Journal of Nutrition and Health
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    • 제29권9호
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    • pp.1035-1041
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    • 1996
  • The study was undertaken to examine the levels of serum lipids and the correlations between serum lipid levels and other factors(nutrient intakes, anthrometric measurement, blood pressure, drinking, smoking). The participants in this study were healthy volunteers over the age of 40 residing in Whachon area, Kang-Wan Do. The level of serum TG was higher in males than in females, particularly in age of 40(209.8mg/dl$\pm$154.9, p<0.05). The HDL-c/total cholesterol ratio(HTR) in males was the lowest(0.23$\pm$0.07, p<0.05) in age of 40 and in females was the lowest(0.25$\pm$0.1) in age of 60 and over. LDL-c/HDL-c ratio(LHR) was the highest (males 3.64$\pm$6.29, females 3.28$\pm$3.03) in age of 40 in both sexes. In the age of 40-59, serum TG, total cholesterol and LDL-cholesterol and HDL-cholesterol tended to increase with BMI. Serum TG showed positive correlation with drinking (r=0.026, p<0.001) and BMI (r=0.2096, p<0.01). BMI was negatively correlated with HTR(r=-0.2242, p<0.01) and HDL-cholesterol (r=-0.2054, p<0.01).

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DME 예혼합기를 분위기로 하는 디젤 분무의 연소에 관한 연구 (The investigation of Diesel Spray Combustion in DME HCCI)

  • 임옥택;노리마사 이이다
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회B
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    • pp.3329-3334
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    • 2007
  • The purpose of the research is to investigate of diesel spray combustion for simultaneously reduce way NOx and PM. The pressure diesel injection were done into intermediates that are generated by very lean DME HCCI combustion using a RCM. The concentration of intermediate could not be directly measured; we estimated it by CHEMKIN calculation. DME HCCI characteristic is surveyed. Validations of the CHEMKIN calculation were confirmed pressure rise of an experiment and pressure rise of a calculation. Using a framing streak camera captured two dimensional spontaneous luminescence images from chemical species at low temperature reaction(LTR) and high temperature reaction (HTR). Also, the combustion events were observed by high-speed direct photography, the ignition and combustion were analyzed by the combustion chamber pressure profiles.

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DME 예혼합 자기착화 연소중의 디젤분무연소에 관한 연구 (The Investigation of Diesel Spray Combustion in DME HCCI Combustion)

  • 임옥택
    • 대한기계학회논문집B
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    • 제32권4호
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    • pp.241-248
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    • 2008
  • The purpose of the research is to investigate of diesel spray combustion for simultaneously reduction way of NOx and PM. The diesel injection were done into intermediates that are generated by very lean DME HCCI combustion using a RCM. The concentration of intermediate could not be directly measured, so we estimated it by CHEMKIN calculation. Two dimensional spontaneous luminescence images which are created by chemical species reaction at low temperature reaction (LTR) and high temperature reaction (HTR) are captured by using a framing streak camera. Also, combustion events were observed by high-speed direct photography. The ignition and combustion events were analyzed by pressure profiles and the KL values and flame temperatures were analyzed by the two-color method.

Experimental research on vertical mechanical performance of embedded through-penetrating steel-concrete composite joint in high-temperature gas-cooled reactor pebble-bed module

  • Zhang, Peiyao;Guo, Quanquan;Pang, Sen;Sun, Yunlun;Chen, Yan
    • Nuclear Engineering and Technology
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    • 제54권1호
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    • pp.357-373
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    • 2022
  • The high-temperature gas-cooled reactor pebble-bed module project is the first commercial Generation-IV NPP(Nuclear Power Plant) in China. A new joint is used for the vertical support of RPV(Reactor Pressure Vessel). The steel corbel is integrally embedded into the reactor-cabin wall through eight asymmetrically arranged pre-stressed high-strength bolts, achieving the different path transmission of shear force and moment. The vertical monotonic loading test of two specimens is conducted. The results show that the failure mode of the joint is bolt fracture. There is no prominent yield stage in the whole loading process. The stress of bolts is linearly distributed along the height of corbel at initial loading. As the load increases, the height of neutral axis of bolts gradually decreases. The upper and lower edges of the wall opening contact the corbel plate to restrict the rotation of the corbel. During the loading, the pre-stress of some bolts decreases. The increase of the pre-stress strength ratio of bolts has no noticeable effect on the structure stiffness, but it reduces the ultimate bearing capacity of the joint. A simplified calculation model for the elastic stage of the joint is established, and the estimation results are in good agreement with the experimental results.

Operation optimization of auxiliary electric boiler system in HTR-PM nuclear power plant

  • Du, Xingxuan;Ma, Xiaolong;Liu, Junfeng;Wu, Shifa;Wang, Pengfei
    • Nuclear Engineering and Technology
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    • 제54권8호
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    • pp.2840-2851
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    • 2022
  • Electric boilers (EBs) are the backup steam source for the auxiliary steam system of high-temperature gas-cooled reactor nuclear power plants. When the plant is in normal operations, the EB is always in hot standby status. However, the current hot standby operation strategy has problems of slow response, high power consumption, and long operation time. To solve these problems, this study focuses on the optimization of hot standby operations for the EB system. First, mathematical models of an electrode immersion EB and its accompanying deaerator were established. Then, a control simulation platform of the EB system was developed in MATLAB/Simulink implementing the established mathematical models and corresponding control systems. Finally, two optimization strategies for the EB hot standby operation were proposed, followed by dynamic simulations of the EB system transient from hot standby to normal operations. The results indicate that the proposed optimization strategies can significantly speed up the transient response of the EB system from hot standby to normal operations and reduce the power consumption in hot standby operations, improving the dynamic performance and economy of the system.

천마분말 복용이 심혈관계 질환 노인들의 혈중 지질 양상 변화에 미치는 영향 (The Effects of Gastrodiae Rhizoma Powder on Plasma Lipid Profiles in the Elderly with Cardiovascular Disease)

  • 양경미
    • 한국식품영양과학회지
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    • 제37권7호
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    • pp.858-868
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    • 2008
  • 평균 수명과 노인 연령층의 증가에 따른 노인들의 삶의 질적 향상을 위하여 보다 적극적인 건강증진 방안이 요구된다. 이에 본 연구에서는 영양군 마을 주민들 중에서 60세 이상으로 고혈압, 당뇨병, 고지혈증 진단 및 유소견자 중 자원자 32명을 대상으로 2006년 9월 14일에서 2007년 3월 13일까지 6개월 동안 천마복용 전후의 설문조사와 혈액학적 지질성분 변화 양상에 대한 천마의 효과를 살펴 본 결과는 다음과 같다. 조사대상자의 전체 평균 연령은 $65.7{\pm}7.84$세로 남자는 $70.0{\pm}6.24$세, 여자는 $63.3{\pm}7.76$세이었다. 전체 평균키와 몸무게는 각각 $152.5{\pm}28.9\;cm$, $57.6{\pm}10\;kg$이었으며, 남자 노인은 $165.3{\pm}5.86\;cm$461.7{\pm}11.7\;kg$, 여자 노인은 $143.7{\pm}34.9\;cm$$54.4{\pm}8.03\;kg$로 표준 체격보다 작았고 남자 노인에 비해서 여자 노인의 비만도가 다소 높았다. 질병보유상태는 전체 조사대상자의 81.3%로 고혈압, 근골격 질환, 당뇨병, 심장병, 신경통 등을 앓고 있었다. 약물복용 상태는 조사대상자의 53.1%가 현재 복용하고 있는 약물은 없었으며, 한 가지 약물복용은 남녀 각각 18.2%, 38.1%, 두 가지 약물복용은 9.1%, 9.5%로 남자 노인이 여자 노인보다 약물 복용수가 많았다. 조사대상자의 식태도는 남자에 비해서 여자가 채소와 과일의 섭취 빈도수가 높았으나 남녀 모두 육류와 생선의 빈도수가 낮았다. 1회 식사량은 조사대상자의68.8%가 보통수준이었으며 조사대상자의 87.1%가 균형식으로 먹는다고 답하였다. 또한 영양위험도 평가에서는 고위험 영양불량군이 남녀 각각 81.8%, 76.2%로 고위험 영양불량상태인 조사대상자의 비율이 높았다. 조사대상자의 천마복용 전후의 남녀의 혈압, 혈당 및 헤모글로빈의 평균 수치는 모두 정상 범위 내에 있었으며, 천마복용으로 남자의 경우 p<0.05 수준에서 이완기혈압이 증가된 반면에 혈당이 감소되었다. 혈액 내 중성지방, 총콜레스테롤, LDL과 HDL-콜레스테롤 역시 천마복용 전후 남녀의 평균 수치는 모두 정상범위 내에 있었다. 남자의 경우 p<0.05 수준에서 중성지방은 감소된 반면에 HDL-콜레스레롤은 p<0.05 수준에서 천마복용 전에 비하여 복용 후에 증가되는 경향을 보였다. 그러나 동맥경화나 심혈관계 위험 지수에 있어서는 남녀 모두 천마복용으로 유의적으로 호전된 양상을 보였다. 남녀 성별에의한 영향을 통제하고 천마복용의 효과를 분석하기 위하여 공변량 분석을 실시한 결과 천마복용이 최고혈압, 최저혈압, 헤모글로빈, 중성지방, 총콜레스테롤, HDL-콜레스테롤, LDL-콜레스테롤, AI, CRF 그리고 HTR에는 유의적인 영향은 미치지 못하였다. 그러나 천마복용이 p<0.01 수준에서 혈당치와 p<0.05 수준에서 LHR에는 영향을 미친 것으로 나타났다. 본 연구의 제한점으로는 기본적으로 본 연구의 참여 대상자를 자원자 중심으로한 결과 이들 중 56% 정도가 혈당강하제, 고지혈증 및 고혈압 약을 복용하면서 천마를 섭취했다는 한계점 때문에 천마복용 전후 혈압과 혈중 지질성분이 정상 기준치 범위 내에 있었으며, 그 결과 혈당, 혈압 및 지질성분에 대한 뚜렷한 함량 변화가 나타나지 않은 것으로 추측된다. 따라서 앞으로 천마를 이용한 건강기능식품의 생리효과를 검증하기 위한 실험을 수행하고자 할 때는 정상인, 고지혈증 환자, 고혈압 환자, 약물 복용자 및 비복용자 등 각 항목에 대한 정상군과 위험군을 대상으로 한 광범위한 연구가 수행되어야 한다고 본다. 또한 조사대상자의 혈압과 혈중 지질성분에 대하여 천마 이외에 다른 관련 인자가 미치는 효과에 대한 분석도 필요하다고 본다. 그러나 본 연구결과에서 천마의 복용으로 동맥경화나 심혈관계 질환에 관련된 위험지수가 저하된 결과를 통해서 볼 때 심혈관계 질환의 예방이나 치료의 목적을 위해 한의학적으로 사용되고 있는 천마의 심혈관계 질환에 효능이 있는 것으로 여겨지며 천마를 이용한 다양한 건강식품이 개발되어 국민 건강 향상에 이바지할 수 있으리라 기대된다.

초기 성인기 우울증에 대한 유전적, 환경적 요인의 영향 (Effects of Genetic and Environmental Factors on the Depression in Early Adulthood)

  • 김시경;이상익;신철진;손정우;엄상용;김헌
    • 생물정신의학
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    • 제15권1호
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    • pp.14-22
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    • 2008
  • 우울 장애는 유전적 요인과 함께 환경적 요인이 복합적으로 작용하는 정신 장애이다. 본 연구에서는 세로토닌 체계와 연관된 유전적 요인과 생활사건과 같은 환경적 요인이 초기 성인기 우울 장애 발현에 미치는 영향을 조사함으로써 우울 장애의 원인론에 있어 유전자${\times}$환경 상호작용을 설명할 수 있는 자료를 제시하고자 하였다. 534명의 대학 신입생을 종적으로 추적 조사하여 생활사건 빈도와 중요도, 우울 척도와 불안 척도를 조사하였으며 전화 면담을 통해 DSM-IV 우울 장애 여부를 확인하였다. 최종적으로 150명이 연구에 포함되었으며 이전 연구로 확인된 TPH1 유전형과 함께 보관되어 있던 대상군의 DNA를 이용하여 SNaPshot$^{TM}$ 방식으로 TPH2, 5HTR2A 유전자를 추가 분석하였다. 유전자 정보와 생활사건 특성이 우울 증상에 미치는 영향을 확인하기 위해 로지스틱 회귀 분석과 상관 분석, 카이 자승 분석을 사용하였다. TPH1 유전형 중 C 대립 유전자가 존재하지 않는 집단과 달리 C 대립 유전자가 존재하는 집단에서는 생활사건 빈도가 우울 장애 유발에 유의한 영향을 미쳤다. 이러한 영향은 다른 대립 유전자나 유전형을 보이는 집단에서는 관찰되지 않았다. 본 연구의 결과는 TPH1 유전형은 생활사건 이후 우울 장애 발생의 유의미한 예측 요인임을 시사한다. 이는 우울 장애의 유전${\times}$환경 상호작용에 TPH1 유전자가 작용하고 있음을 제시한다.

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