• Title/Summary/Keyword: HS

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The Relationship between Metabolic Syndrome Risk Factors and High Sensitive C-reactive Protein in Abdominal Obesity Elderly Women (복부비만 고령여성의 대사증후군 위험요인과 고감도 C-반응성 단백의 관련성)

  • Shin, Kyung-A
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.2
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    • pp.121-127
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    • 2017
  • High sensitive C-reactive protein (hs-CRP) has been associated with metabolic syndrome (MetS) and its risk factors. This study aimed to evaluate the association between hs-CRP and the risk factors of MetS in elderly women with abdominal obesity. The diagnosis of MetS followed the AHA/NHLBI criteria, and abdominal obesity was defined using the WHO Asian-Pacific criteria. We used the data from 174 elderly women, with an average age of 74 years. They were classified into two groups: The absent group (N=97) and the MetS group (N=77). Hs-CRP was significantly higher in the MetS group (p=0.007). Hs-CRP had a positive correlation with abdominal obesity (r=0.190, p=0.014) and fasting blood glucose (r=0.240, p=0.002), while having a negative correlation with HDL cholesterol (r=-0.164, p=0.035). Moreover, hs-CRP was higher in the group with risk of high fasting blood glucose (p=0.006) and low HDL-cholesterol (p=0.010), even in elderly women with abdominal obesity.

A HS tariff classification service based on a knowledge convergence performance system supporting decision elements and field terms (결정요소 및 현장용어 지원 지식융합 수행 시스템 기반의 HS 관세분류 서비스에 관한 실증 연구)

  • Kim, Eunsoo;Song, ByungJun;Lee, Jong Yun
    • Journal of the Korea Convergence Society
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    • v.6 no.1
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    • pp.49-55
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    • 2015
  • In the FTA environment, it is necessary to comply with the rules of origin in order to receive duty-free benefits. To do this, they have to precede the Harmonized System(HS) tariff classification of the goods and understand thoroughly the basic principles that constitute the tariff schedule of HS classification. For the correct classification, they should understand exactly the product name of "Heading" about the items, "Legal Note" in the relevant "Section" or "Chapter" as well as provisions of the commentary. Therefore, this paper proposes to develop a HS classification services based on the performance system of knowledge convergence of field terms commonly used in various industries. In result, our services can provide users the conveniences which users first selects one of seven decision elements of the classification and perform the classification easily and accurately.

Remediation of heavy metal-contaminated soils using eco-friendly nano-scale chelators

  • Lim, Heejun;Park, Sungyoon;Yang, Jun Won;Cho, Wooyoun;Lim, Yejee;Park, Young Goo;Kwon, Dohyeong;Kim, Han S.
    • Membrane and Water Treatment
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    • v.9 no.3
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    • pp.137-146
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    • 2018
  • Soil washing is one of the most frequently used remediation technologies for heavy metal-contaminated soils. Inorganic and organic acids and chelating agents that can enhance the removal of heavy metals from contaminated soils have been employed as soil washing agents. However, the toxicity, low removal efficiency and high cost of these chemicals limit their use. Given that humic substance (HS) can effectively chelate heavy metals, the development of an eco-friendly, performance-efficient and cost-effective soil washing agent using a nano-scale chelator composed of HS was examined in this study. Copper (Cu) and lead (Pb) were selected as target heavy metals. In soil washing experiments, HS concentration, pH, soil:washing solution ratio and extraction time were evaluated with regard to washing efficiency and the chelation effect. The highest removal rates by soil washing (69% for Cu and 56% for Pb) were achieved at an HS concentration of 1,000 mg/L and soil:washing solution ratio of 1:25. Washing with HS was found to be effective when the pH value was higher than 8, which can be attributed to the increased chelation effect between HS and heavy metals at the high pH range. In contrast, the washing efficiency decreased markedly in the low pH range due to HS precipitation. The chelation capacities for Cu and Pb in the aqueous phase were determined to be 0.547mmol-Cu/g-HS and 0.192mmol-Pb/g-HS, respectively.

The Role of HS-1200 Induced Autophagy in Oral Cancer Cells

  • Jang, Nam-Mi;Oh, Sang-Hun;Kim, In-Ryoung;Park, Hae-Ryoun;Park, Bong-Soo
    • International Journal of Oral Biology
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    • v.38 no.3
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    • pp.93-100
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    • 2013
  • Bile acids and synthetic bile acid derivatives induce apoptosis in various kinds of cancer cells and thus have anticancer properties. Recently, it has been suggested that autophagy may play an important role in cancer therapy. However, few data are available regarding the role of autophagy in oral cancers and there have been no reports of autophagic cell death in OSCCs (oral squamous cell carcinoma cells) induced by HS-1200, a synthetic bile acid derivative. We thus examine whether HS-1200 modulates autophagy in OSCCs. Our findings indicate that HS-1200 has anticancer effects in OSCCs, and we observed in these cells that autophagic vacuoles were visible by monodansylcadaverine (MDC)and acridine orange staining. When we analyzed HS-1200-treated OSCC cells for the presence of biochemical markers, we observed that this treatment directly affects the conversion of LC-3II, degradation of p62/SQSTM1 and full-length beclin-1, cleavage of ATG5-12 and the activation of caspase. An autophagy inhibitor suppressed HS-1200-induced cell death in OSCCs, confirming that autophagy acts as a pro-death signal in these cells. Furthermore, HS-1200 shows anticancer activity against OSCCs via both autophagy and apoptosis. Our current findings suggest that HS-1200 may potentially contribute to oral cancer treatment and thus provide useful information for the future development of a new therapeutic agent.

Effect of heat stress on growth performance and blood profiles in finishing pigs

  • Kim, Byeonghyeon;Kim, Hye Ran;Kim, Ki Hyun;Kim, Minji;Baek, Youl-Chang;Lee, Sung Dae;Jeong, Jin Young
    • Korean Journal of Agricultural Science
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    • v.47 no.3
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    • pp.683-691
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    • 2020
  • A biomarker is needed to monitor and manage the health of pigs from heat stress (HS). Therefore, we investigated the effects of HS on growth performance, nutrient digestibility, and blood profiles in finishing pigs. A total of 12 finishing pigs (n = 12) were raised in thermal neutral (TN; 25℃) conditions for a 3-d adaptation period. After the adaption, 6 pigs were exposed to HS at 33℃ (HS33) for 5 d. The pigs were fed the same diet based on corn and soybean meal. Chromic oxide was added to all the diets at a level of 2 g·kg-1 as an indigestible marker for the determination of the apparent total track digestibility (ATTD) of nutrients and amino acids. Blood samples were collected after the adaptation and heat treatment to verify the blood profiles. The HS33 pigs had a lower (p < 0.01) average daily feed intake (ADFI) and higher (p < 0.05) rectal temperature compared to the TN pigs. However, there was no difference in the ATTD of nutrients and amino acids. The HS33 pigs had reduced (p < 0.05) levels of serum glucose, non-esterified fatty acids (NEFA), total protein, albumin, and calcium compared to the TN pigs. However, the level of total bilirubin was increased (p < 0.05) in the HS pigs. In conclusion, HS reduced the feed intake and had an adverse effect on health. Altered blood profiles as a result of a negative energy balance are expected to be biomarkers of HS in finishing pigs.

Comparison of hs-CRP and Lipid Values Between Hypertensive and Normotensive Groups (고혈압군과 정상혈압군 환자에서 hs-CRP와 지질 측정값의 비교)

  • Park, Eun-Jung;Kim, Young-Ah;Lim, Dong-Soo;Gee, Myung-Suk;You, Seun-Woo;Woo, Hee-Yeon
    • Korean Journal of Clinical Laboratory Science
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    • v.37 no.3
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    • pp.185-189
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    • 2005
  • Lipids such as total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C) and high sensitivity C-reactive protein (hs-CRP) are known as good risk factors for coronary artery diseases caused by arthrosclerosis. We measured the serum concentrations of hs-CRP, TC, and HDL-C of 6,128 persons who underwent medical examinations in the Health Screening Center at Kangbuk Samsung Hospital. We classified the subjects into normotensive and hypertensive groups according to the blood pressure measured. We investigated whether there was a difference of hs-CRP and lipids between the normotensive and hypertensive groups. There was significant difference of TC, TC/HDL-C ratio, and hs-CRP concentration between the normotensive and hypertensive groups in both men and women, but there was no significant difference of HDL-C concentration between two groups. Our results indicated that the concentrations of hs-CRP and lipids were higher in patients with hypertension and confirmed the usefulness of lipids and hs-CRP in predicting the risk for coronary artery diseases.

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Effects of Hypochlorous Acid, Calcium Chloride and Phosphoric Acid in a Highly Saline Solution on Cell Death Rate and Growth Rate of Porphyra yezoensis and Ulva intestinalis (고염수 처리제에 차아염소산, 염화칼슘 및 인산 첨가가 방사무늬김(Pyropia yezoensis)과 창자파래(Ulva intestinalis)의 사세포율과 엽체 성장에 미치는 영향)

  • Kwon, O-Nam;Yun, Yeoung-Rang;Shin, Il-Shik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.51 no.6
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    • pp.682-687
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    • 2018
  • We investigated the effects of a highly saline solution (HS) containing hypochlorous acid, calcium chloride ($CaCl_2$), and phosphoric acid ($H_3PO_4$) on cell death and growth rate of laver Porphyra yezoensis and green laver Ulva intestinalis. Cell death rates of laver treated with HS and HS plus hypochlorous acid (HS + HOCl) in the harvesting stage were less than 0.5%, and there were no significant differences between the HS and HS + HOCl treatments. However, cell death of green laver treated with HS + HOCl in the harvesting stage was greater than 81.2%. These results indicate that the addition of HOCl is highly effective to eradicate noxious green laver without causing damage to laver. The addition of HOCl and $H_3PO_4$ to HS did not increase the area or weight of laver blades. A combination treatment of $CaCl_2$ and HS, however, significantly increased the area and weight of laver lades compared to controls (P<0.05).

Heat stress effects on fertility and reproductive health problems of dairy cows in a selected area of Bangladesh

  • Rifat J. Sumi;Ziban C. Das;Mohammad N. Hoque;Abu N. M. A. Rahman;Mohammad T. Islam;Anup K. Talukder
    • Journal of Animal Reproduction and Biotechnology
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    • v.37 no.4
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    • pp.266-275
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    • 2022
  • The impact of heat stress (HS) on reproductive performance and its problems in cows remains to be investigated in Bangladesh. The study was, therefore, aimed to evaluate the effect of HS on fertility and reproductive health problems of dairy cows in a selected area of Bangladesh. A total of 1,095 cows from 500 farms were included in this study. The climate-related data were recorded daily basis for every month in a year and temperature-humidity index (THI) values were calculated to determine the level of HS. Concurrently, data on fertility parameters [number of services per conception (NSC), conception rate (CR) and calving to the first service interval (CFSI)], and reproductive problems were collected through a pre-defined questionnaire. The results show that crossbred [Native x Holstein-Friesian, (HF)] cows were more vulnerable (p < 0.05) to a magnitude of HS effects considering physiological parameters of cows [age, body condition score (BCS), parity and milk yield]. Regarding fertility, HS had no effect on NSC, CR and CFSI in both native and crossbred cows (p > 0.05). The findings on the reproductive problems indicate that HS had significant influence on the prevalence of anestrus (χ2 = 21.814, p < 0.05) and retained placenta (χ2 = 24.632, p < 0.05) in cows. Of note, the prevalence of repeat breeding syndrome was 2.5 folds higher in stress condition than in no stress condition. Abortion and dystocia were not influenced by HS. In conclusion, HS does not influence the fertility parameters of cows studied; however, anestrus and retained placenta are likely to occur under HS conditions in cows.

A Study on the Unmanned Transportation Systems of the Seventh Edition of Harmonized System: Focusing on the Section 17 of HS Nomenclature (제7차 HS 협약 개정에 따른 무인 수송기기 품목분류에 관한 연구: 제17부를 중심으로)

  • Jin-Kyu Kim;Yoon Lee
    • Korea Trade Review
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    • v.46 no.5
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    • pp.49-63
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    • 2021
  • The HS Convention is an agreement on the harmonized commodity description and coding system enacted by the World Customs Organization in January 1988 to promote international trade and unify the commodity classification systems internationally, and the seventh revision will take effect in January 2022. This study's main purpose is to consider criteria for classifying unmanned autonomous transport systems(UATS) in accordance with Section 17 of the HS nomenclature and to present recommendations for improvement of laws related to tariff classification which may be used to amend related laws in Korea. Currently, there are no provisions within the HS Nomenclature that classify unmanned autonomous transportation systems and equipments. Although such technologies have yet to be commercially deployed, they are being actively developed globally. Thus, this study aims to classify UATS and suggest appropriate amendments to the new edition of the HS Nomenclature and Korean law. This paper examines advance ruling cases from domestic and foreign HS classification under the revision of the HS Convention and the criteria for the classification of UATS and Domestic Korean and foreign classification case studies were investigated, along with a survey of the literature on UATS, in order to derive reasonable tariff classification criteria and present legislative implications. In conclusion, this study aims to provide legislative recommendations for how to improve the system to apply the revisions to the HS Convention to the domestic Korean statutes.