• Journal of Biomedical Engineering Research
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• v.24 no.1
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• pp.1-8
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• 2003

The job of long distance driving is likely to be fatiguing and requires long period alertness and attention, which make considerable demands of the driver. Driving fatigue contributes to driver related with accidents and fatalities. In this study, we investigated the relationship between the number of hours of driving and driving fatigue using heart rate variability(HRV) signal. With a more traditional measure of overall variability (standard deviation, mean, spectral values of heart rate). Nonlinear characteristics of HRV signal were analyzed using Approximate Entropy (ApEn) and Poincare plot. Five subjects drive the four passenger vehicle twice. All experiment number was 40. The test route was about 300Km continuous long highway circuit and driving time was about 3 hours. During the driving, measures of electrocardiogram(ECG) were performed at intervals of 30min. HRV signal, derived from the ECG, was analyzed using time, frequency domain parameters and nonlinear characteristic. The significance of differences on the response to driving fatigue was determined by Student's t-test. Differences were considered significant when a p value < 0.05 was observed. In the results, mean heart rate(HRmean) decreased consistently with driving time, standard deviation of RR intervals(SDRR), standard deviation of the successive difference of the RR intervals(SDSD) increased until 90min. Hereafter, they were almost unchanging until the end of the test. Normalized low frequency component $(LF_{norm})$, ratio of low to high frequency component (LF/HF) increased. We used the Approximate Entropy(ApEn), Poincare plot method to describe the nonlinear characteristics of HRV signal. Nonlinear characteristics of HRV signals decreased with driving time. Statistical significant is appeared after 60 min in all parameters.

• Science of Emotion and Sensibility
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• v.14 no.2
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• pp.269-278
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• 2011

This paper illustrates the inter-relationship between the theta/alpha ratio of the EEG signal and multiple HRV related parameters associated with the cardiovascular system response during event-related stimuli. Both EEG and PPG signals were simultaneously recorded in 21 healthy subjects. All subjects had their attention focused on the CNT program for nine minutes. Time-frequency analysis was applied to the EEG and PPG signals. The theta/alpha ratio was extracted from the EEG results, and the HRV features, including beat interval(1), SDNN(2), RMSSD(3), NN50(4), LF(5), HF(6), and LFIHF(7), were extracted from the PPG. Through multiple linear regression, the relationship ($R^2$) between the multiple combined features and the theta/alpha rhythm was identified. As a result, the combinations of $R^2$($R^2=0.253$; seven dimensions) and the theta/alpha ratio indicated a higher inter-relationship value than those of other combinations. The combinations of features that were greater than three dimensions, based on {SDNN(2), HF(6)}, generally showed higher $R^2$ value. We demonstrate that the high dimensional combinations had a higher correlation than did the low dimensional combinations.

• Korean Journal of Psychosomatic Medicine
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• v.28 no.1
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• pp.81-88
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• 2020

Objectives : This study aimed to compare autonomic nervous system (ANS) dysregulation and differential relationships with clinical severities between anxiety disorder, depressive disorder, and trauma·stressor related disorder using heart rate variability (HRV) parameters. Methods : We conducted a retrospective chart review of outpatients from 2017 to 2018 in Stress Clinic of National Center for Mental Health. Total 473 patients were included; 166 anxiety disorder; 184 depressive disorder ; 123 trauma·stressor related disorder. Parameters of 5-min analysis of HRV were compared in three groups. Additionally, we investigated the differential association of each parameters with Clinical Global Impression-Severity Scale (CGI-S) across each group. Results : No significant differences were found in all HRV parameters between the three groups. However, significant group interactions by CGI-S were found in standard deviation of all RR intervals (SDNN) and the square root of the mean squared differences of successive normal-to-normal intervals (RMSSD) (SDNN, p=0.017 ; RMSSD, p=0.034). A negative relationship between CGI-S and SDNN, RMSSD has been found in anxiety disorder and depressive disorder. However, a positive relationship between CGI-S and SDNN, RMSSD has been found in trauma·stressor related disorder. Conclusions : Despite of no significant differences of each HRV parameter, our findings suggested the differential associations of HRV parameters with clinical severity among anxiety disorder, depressive disorder and trauma·stressor related disorder. In trauma·stressor related disorder, the clinical severity and degree of ANS dysregulation may differ, so more aggressive treatment is suggested.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.190-193
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• 2001

본 연구는 색채환경이 정상인의 심전도에 미치는 영향을 정량적으로 분석하여 색채 환경이 인체에 미치는 영향을 규명하고자 하였다. 피험자는 색맹을 가지고 있지 않고 인지기능에 장애가 없는 정상 성인 남, 여 50명을 대상으로 하였다. 색채환경의 제시는 암실에서 백색 광원에 채색 필터를 사용하여 제시하였다. 피검자는 6가지 색채 환경 안에서 심전도를 측정하였으며, HRV 분석을 하였다. HF/LF의 비를 비교 분석하여 본 결과, 남자는 녹색에서 색채 자극전보다 자극후가 HF/LF의 비가 0.508(p<0.07) 상승한 것을 볼 수 있었으며, 여자는 파랑색에서 색채자극전보다 자극후 HF/LF의 비가 0.677상승한 것을 볼 수 있었다. 이는 남자는 녹색에서 여자는 파랑색에서 더욱 편안함과 안락감을 느끼게 된다는 것을 의미한다. 따라서 본연구의 결과는 색채 환경이 인체에 미치는 영향을 규명함으로써 좀 더 편안한 색채 환경의 설계에 도움을 줄 것으로 기대된다.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.200-203
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• 2001

감성평가 실험시 피험자가 받는 작업부하의 영향을 실시간으로 평가하기 위하여 측정된 심전도 신호로부터 R-peak를 자동적으로 검출하여 심전도 관련 파리미터를 분석하는 시스템을 개발하였다. 이 시스템은 심전도 증폭기, A/D변환기, PC로 구성되었으며 National Instrument 사의 LabVIEW를 사용하여 소프트웨어를 개발하였다. 시스템 동작환경은 Microsoft사의 Window OS를 기반함으로서 시스템 이용자들에게 보다 친숙한 실험환경을 제시할 수 있다. 구현된 시스템은 실시간 HRV, Lorentz plot, LF/HF, HRV power spectrum의 3차원 선도를 디스플레이할 수 있다.

• Journal of Biomedical Engineering Research
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• v.28 no.4
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• pp.441-448
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• 2007

Heart rate variability (HRV) in electrocardiogram (ECG) is an important index for understanding the health status of heart and the autonomic nervous system. Most HRV analysis approaches are based on the proper heart rate (HR) data. Estimation of heart rate is thus a key process in the HRV study. In this paper, we report an innovative method to estimate the heart rate. This method is mainly based on the concept of periodicity transform (PT) and instantaneous period (IP) estimate. The method presented is accordingly called the "PT-IP method." It does not require ECG R-wave detection and thus possesses robust noise-immune capability. While the noise contamination, ECG time-varying morphology, and subjects' physiological variations make the R-wave detection a difficult task, this method can help us effectively estimate HR for medical research and clinical diagnosis. The results of estimating HR from empirical ECG data verify the efficacy and reliability of the proposed method.

• Proceedings of the KIEE Conference
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• 2006.07d
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• pp.2157-2158
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• 2006

Heart Rate Variability (HRV) system is useful for evaluating the balance in homeostasis of autonomic nervous system. In this study, we implement HRV monitoring system by performing real time FFT spectrum analysis on R-R intervals data acquired from Electrocardiogram (ECG) acquisition and transmitting the data by RF communication module.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.543-543
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• 2000

A new method for HRV(heart rate variability) detection from the R-wave signal, based on the IPFM(integral pulse frequency modulation) model and its similarity to pulse position modulation, is presented. The proposed method exert lowpass filtering with a Kaiser window. In this paper, The proposed method presents a powerful, but simple, tool for investigation of HRV. It also guarantees real-time behavior. simplicity in design, and phase linearity. Even without the basic assumption of IPFM model. the new algorithm can still be used on-line and with higher performance. It is thoroughly proved that lowpass filtering is an ideal method for PSD(Power Spectrum Density) analysis of HRV.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1997.11a
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• pp.118-122
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• 1997

본 연구에서는 온열환경에 따른 쾌적감을 조사하기 위하여 온열환경을 평가할 수 있는 지표로서 생리신호를 분석하였다. 생리신호로는 인체의 자율신경계에 대한 반응을 나타내는 HRV변수 및 대뇌의 각성수준을 나타내는 CNA파형의 변이도를 이용하였다. HRV스펙트럼분석을 통해 얻어진 HF/LF변수를 이용하여 주어진 환경하에서 교감 및 부교감 신경의 활동성을 조사하였고, CNA 파형에서는 경고신호가 주어진 뒤 0.5-1초 구간의 면적값을 이용하여 온열쾌적감과의 상관성이 높게 나타나지 않은 반면, HRV스펙트럼분석에서는 휴지기에 비해 발과 얼굴부위에 대한 HF/LF값이 높은 사실을 통해 교감신경에 비해 부교감신경이 지배적이라는 사실을 알 수 있었다. 이러한 결과는 바과 얼굴이 주위온도에 따른 인체의 쾌적감을 변화시키는데에 있어서 주된 부위임을 나타내며 HRV스펙트럼분석 및 CNV파형의 관찰이 온열환경에 대한 쾌적감을 평가하는데 유용한 지표로 사용될 수 있음을 말해준다.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1997.11a
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• pp.91-94
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• 1997

Objective of this stuey was to find the corrdlation between emotiona changes and the parameters of HRV spectrum evoked by tactile stimualtion. Twenty-one subjects were useds and five different types of materials, dry cottn, wet cotton, paper, sandpaper, and vinyl were applied to the left hand of each subject as a tactile stimulation. The results showed that HF/LF(ratio of high to low frequency amplitude calculated from power spectrum of HRV) decreased as the subject experienced the unpleasant emotion caused by wet cotton and sandpaper. On the othr hand, when the subject experienced the comfort, HF/LF increased. It was concluded that the proprsed methods can be applied to evaluate the characteristic changes in the autonomic nervous system which regulates the human emotion in the psychological aspects.