• 한국융합학회논문지
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• 제12권2호
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• pp.61-66
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• 2021

본 연구의 목적은 지연성근육통의 통증 변화가 자율신경계와 뇌파에 미치는 영향을 알아보고자 하였다. 지연성 근육통이 유발된 28명을 대조군(n=14)과 실험군(경피신경자극과 키네시오테이핑 적용, n=14)으로 구분하였다. 중재는 지연성근육통 유발 1일 후부터 5일 동안 실시하였다. 평가는 VAS(visual analog scale), 심박변이, 뇌파를 사용하여 지연성근육통 유발 전, 유발 24시간 후, 5일 치료 후, 치료 중단 3일 후에 측정하였다. 실험 결과 지연성근육통이 발생하면 교감신경계의 활성 증가 또는 부교감신경계 활성 억제가 되며, 중재로 인한 통증 감소는 반대의 활동이 나타났다. 통증 발생 시 alpha파의 감소가 나타났으나 유의하지 않았다. 본 연구 결과 통증 변화는 자율신경계와 뇌파에 영향을 미침을 알 수 있었으며, 이러한 결과는 통증 관리와 치료 전략 개발 및 연구에 도움이 될 것이다.

• 대한간호학회지
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• 제51권3호
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• pp.294-304
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• 2021

Purpose: This study aimed to investigate objectively measured physical activity (PA) in institutionalized older adults with mild cognitive impairment (MCI) and to elucidate the influence of autonomic nervous function, salivary cortisol, and PA on cognitive functions based on neurovisceral integration model. Methods: Overall cognitive function was evaluated using the mini-mental state examination (MMSE) and executive function was evaluated using semantic verbal fluency test and clock drawing test. Actigraph for PA, HRV and sAA for autonomous function, and the geriatric depression scale for depression were used. Saliva specimens were collected in the morning for sAA and cortisol. Results: Ninety-eight older adults from four regional geriatric hospitals participated in the study. They took 4,499 steps per day on average. They spent 753.93 minutes and 23.12 minutes on average in sedentary and moderate-to-vigorous activity, respectively. In the multiple regression analysis, lower salivary cortisol level (β = - .33, p = .041) and greater step counts (β = .37, p = .029) significantly improved MMSE score. Greater step count (β = .27, p = .016) also exerted a significant influence on verbal fluency, and greater sAA (β= .35, p = .026) was significantly associated with a better clock drawing test result. Conclusion: Salivary cortisol, sAA and physical activity were significantly associated with cognitive functions. To prevent older adults from developing dementia, strategies are needed to increase their overall PA amount by decreasing sedentary time and to decrease salivary cortisol for cognitive function, and to maintain their sympathetic nervous activity for executive function.

• 인간식물환경학회지
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• 제24권5호
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• pp.545-550
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• 2021

Background and objective: With increasing land use intensity in urban areas, apartment buildings have been recognized as a typical type of urban residence. In this study, the impacts of different views through a window on health-related responses were investigated using psychological and physiological parameters. Methods: Photos of three different types of views taken on low (2-12 m), middle (28-35 m), and high (over 54 m) floors of dense apartment building areas were used as visual stimuli. Twenty-two healthy adults participated in the indoor experiment. Semantic differential methods and profile of mood states were used as psychological tools. Autonomic nervous activity was evaluated using blood pressures, pulse rate and heart rate variability (HRV). Results: Analytic data showed different characteristics of psychological and physiological outcomes in three different apartment views. In the analysis of psychological parameters, significantly negative responses to the views on middle floors were found in the subscales of tension-anxiety and anger-hostility, compared to low floors. Significantly positive scores in the subscale of vigor were found on low floors with abundance of vegetation and high floors with a view of the sky. A significantly increased value of HF was found on low floors (2,294.96 ± 169.79), compared to the middle(1,553.45 ± 84.66) and high (1,523.02 ± 70.49) floors. Despite the high scores in openness and vigor, high floor views showed significantly higher LF/HF values (1.83 ± 0.09), the indicator of the sympathetic nervous system, than low (1.30 ± 0.07) and middle floor views (1.34 ± 0.06), which might be related to the unconscious fear of heights. Conclusion: Views from different heights in an apartment building can affect the psychological states of residents. Green space through the window may have a positive health outcome by reducing physiological stress.

• 사상체질의학회지
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• 제36권1호
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• pp.13-30
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• 2024

Objectives This study aimed to analyze the influence of various sleep-related factors that affect sleep quality by each Sasang type. Methods A total of 400 subjects were included for this study, 108 males and 292 females. Sasang type was diagnosed using the SCAT. Then, the characteristics of each Sasang type were analyzed using HRV, DITI, and PSQI, PSS, and SDFI questionnaires. Logistic regression analysis was used to predict sleep-related factors that affect sleep disorders by Sasang types. Results This study shows that the pathophysiological characteristics for stress and digestive function of each Sasang type can differentiate sleep management through a logistic regression model including subscales of PSS and SDFI. Stress had no effect on the occurrence of sleep disturbance within only So-Eum, since the stress level is originally high in the So-Eum regardless of sleep quality. Rather, decreased appetite and poor eating habits had a significant impact on the decline in sleep quality. In addition, poor digestion and eating habits in So-Yang had a greater impact and poor digestion in Tae-Eum had a greater impact on the decline in sleep quality. Conclusion The stress and subscales of digestive function provide differentiated sleep management in So-Yang, Tae-Eum, and So-Eum types. The individualized sleep management for each Sasang type with statistically validated PSS and SDFI would be useful for sleep-related experts planning safe and effective person-centered health care as well as for Western clinicians who want to incorporate Sasang typology into their treatments as integrative medical technique in the future.

• 대한한의학회지
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• 제45권1호
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• pp.251-256
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• 2024

Objectives: The purpose of this study was to report the short-term blood pressure-lowering effects observed in a patient with malignant hypertension through slow breathing maneuver with heart rate variability(HRV) biofeedback. Methods: Biofeedback sessions, totaling 13, each lasting 10 minutes, were administered. Blood pressure was measured pre and post-treatment, as well as thrice daily at 10 am, 4 pm, and 8 pm. Systolic blood pressure(SBP), diastolic blood pressure(DBP), and pulse rate were recorded for comparative analysis. Results: Before biofeedback, the average SBP, DBP, and pulse rate were 227.2±18.3, 135.2±11.0, and 104.4±5.3, respectively. Immediately post-biofeedback, these values changed to 213.7±15.2, 126.9±8.5, and 99.2±3.6. However, sustained long-term blood pressure reduction was not observed. Conclusions: The findings suggest that biofeedback therapy induces a short-term reduction in blood pressure in cases of malignant hypertension, potentially associated with autonomic nervous system regulation. Integrating biofeedback with other Korean medicine treatments, such as acupuncture or moxibustion, may offer a comprehensive approach for managing malignant hypertension.

• 대한한의학회지
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• 제30권1호
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• pp.120-127
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• 2009

Objectives: Sahyangsohapwon (SS) is a herbal medication that has been widely used with circulatory and neural diseases. This study was conducted to assess the effect of SS on the autonomic nervous system by using heart rate variability measurement. Methods: The eligible subjects were enrolled from the healthy male group of ages 20 to 35 years. They were divided into two groups, the SS group (n=26) and the control (n=24). We monitored the ECG of subjects from the time period 14:00 to 18:00. In the SS group, subjects were administered with a dose of SS at the time 15:00, whereas the control group had none. For each hour HRV measurement was monitored every 15 minutes for 512 seconds from the time period 14:00 to 18:00. The mean value, which was calculated using the 4 values during each hour (i.e. 14:00, 14:15, 14:30, 14:45), was used as the representative value for each individual hour. For the measurement values, RR-interval and SDNN (standard deviation of the NN intervals) were used as time domain analysis, and HF (high frequency), LF (low frequency), and LF/HF ratio were used as frequency domain analysis. Results: The LF value showed an increase after one hour of SS administration and showed gradual diminution for each and every hour. The repeated measures of ANOVA for the comparison of the LF value between the SS group and the control group showed significant differences. While, RR interval, SDNN, HF, and LF/HF ratio values showed no significant differences between the two groups. Conclusions: We suggest that the SS might be useful for stabilizing autonomic nervous system by inhibiting sympathetic nerve activation in healthy people.

• Journal of Acupuncture Research
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• 제22권3호
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• pp.137-144
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• 2005

본 저자는 2004년 3월 9일부터 2004년 5월15일까지 경희의료원 침구과 외래를 내원한 특발성 파킨슨병 환자를 대상으로 하여 파킨슨병 증상의 호전도를 판단하는 임상척도인 H-Y stage에 따른 HRV를 관찰한 결과 다음과 같은 결론을 얻었다. 1. 시간영역분석에서 H-Y stage I, II, III 그룹의 SDNN은 $28.21{\pm}10.10$, $22.25{\pm}11.26$, $14.57{\pm}5.31$으로 그룹 I과 그룹III 간에는 유의한 차이가 있었다(P<0.05). RMS-SD는 $19.23{\pm}13.27$, $14.63{\pm}6.44$, $6.44{\pm}2.32$ 으로 역시 그룹 I과 그룹III 간에는 유의한 차이가 있었 다(p<0.05). 2. 주파수영역분석에서 TP는 H-Y stage Ⅰ, II, III 그룹에서 각각 $499.86{\pm}345.45$, $243.72{\pm}212.22$, $99.44{\pm}51.01$로 ANOYA 검정결과 p-value가 0.007로 매우 유의 있었으며, 사후 검정에서는 그룹 I과 II, 그룹 II와 III에서는 유의한 차이가 없었으나 그룹 I과 III에서는 매우 유의한 차이가 있었다(p<0.01). LF는 H-Y stage I과 III 그룹에서 유의한 차이가 있었으나(p<0.05) VLF, HF, LF norm HF nonm LF norm, LF/HF ratio에서는 각 그룹 간 유의한 차이가 없었다. 3. SDNN, RMS-SD, TP가 UPDRS 총점이 증가함에 따라 유의성 있게 감소하는 경향 (p<0.05)을 보이는 것으로 보아 파킨슨병이 진행함에 따라 자율신경계의 활동성이 저하될 것으로 보인다.

• 한국심리학회지ㆍ건강
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• 제14권2호
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• pp.277-292
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• 2009

급성 스트레스 상황에 따른 Type D 성격의 자율신경계 반응을 심박률 변동성을 중심으로 조사하였다. Type DS-14의 점수에 근거하여 Type D 집단(n=23명)과 non-Type D 집단(n=23명)을 구성하였다. 심박률 변동성(heart rate variability, HRV)을 이용하여 기저선, 스트레스 단계 및 회복 단계 동안의 심박활동을 측정하였으며 스트레스 과제로는 Stroop 색채단어 검사가 사용되었다. 반복측정 변랑분석을 통해 두 집단의 심박활동을 비교하였으며, 회귀분석을 통해 Type D 척도와 스트레스 취약성 척도가 기저선 상태에서의 심박활동의 변화를 예측할 수 있는지를 알아보았다. 연구 결과, Type D 집단은 non-Type D 집단보다 고주파수(high frequency, HF) 활성화가 더 낮았고 저주파수(low frequency, LF) 활성화는 더 높았다. 스트레스 과제 수행 시, non-Type D 집단에서는 교감신경계 활성화 지표(LF component, LF/HF)가 증가하고 부교감신경계 활성화 지표(HF component)가 감소하는 것이 관찰된 반면, Type D 집단에서는 심박활동 비율상의 유의한 변화가 나타나지 않았다. 또한, Type D 척도의 총점수, 부정적 정서 소척도와 사회적 억제 소척도는 기저선 상태에서의 심박활동 반응에 대한 유의한 예측인자로 나타났다. 이러한 결과는 Type D 성격이 non-Type D 성격에 비해 교감신경계 활성화 비율이 높거나 또는 부교감신경계 활성화비율이 낮음을 시사한다. 즉, Type D가 스트레스에 취약한 성격임을 시사하며, Type D에서 관찰된 심박 활동 양상, 즉 높은 교감신경계 혹은 낮은 부교감신경계 활성화는 Type D 성격이 심장혈관 장애 등을 포함한 정신신체 질환과 관련될 수 있음을 시사한다.

• 동의신경정신과학회지
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• 제23권3호
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• pp.47-62
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• 2012

Objectives : This study is to figure the relations of the heart rate variability, body component analysis and accompanying symptoms of 350 insomnia patients. Methods : For this study we evaluated Heart Rate Variability(HRV) and body component analysis on 350 insomnia patients who visited Dongeui oriental hospital of Dongeui university from January 2008 to March 2012. The accompanying symptoms was collected based on each patient's progress note. Results : 1. There was no difference between PR, LF and VLF of male and female groups. HF was higher in the patients' of female group and LF/HF ratio was higher in the male group. The patients' group of age under 39 had higher HF, LF, VLF and LF/HF ratio than the group over 39. 2. The average of LF was the smallest, and the average of VLF was in the middle, while the average of HF was the largest. 3. Regarding patients' age and gender, as the patients' age increased, their HF, LF, VLF and LF/HF ratio decreased significantly. HF, LF, VLF, and LF/HF ratios were, however, independent on the patients' gender. As the patients' age increased, their BMI increased, while the patients' gender did not affect on their BMI. The amount of visceral fat increased with the patients' age, but wasn't dependent on the patients' gender. 4. As the patients' BMI increased, PR and LF decreased. As the patients' amount of visceral fat increased, PR, HF, LF and VLF decreased. 5. The most frequent accompanying symptoms of the insomnia patients was headache. Neither HF nor LF/HF ratio was dependant on any of the accompanying symptoms. Patients with anxiety showed significantly higher LF than those without anxiety. Patients with fatigue and physical pain showed significantly higher VLF than those without either of them. Conclusions : The study showed that as the insomnia patients age increased, the HF, LF, VLF, LF/HF ratio significantly decreased, but the BMI and visceral fat increased. The HF, LF, VLF, LF/HF ratio BMI, or the visceral fat was independent on the gender. As BMI increased, PR and LF decreased. As visceral fat increased, PR HF, LF and VLF decreased. Patients presenting anxiety had higher LF. Patients either with fatigue or physical pain had higher VLF. Neither HF nor LF/HF ratio had any significant correlation with any of the accompanying symptoms.

• 한국조경학회지
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• 제43권5호
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• pp.1-12
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• 2015

본 연구는 숲의 종류에 따른 이용자의 생리적 효과를 분석하기 위하여 실시하였다. 숲은 편백나무숲, 졸참나무숲, 소나무 숲으로 구분하고, 실험대상 집단은 고혈압 환자(64명), 당뇨병 환자(59명) 및 일반인(59명)으로 구분하여 생리적 반응을 측정하였다. 생리적 반응은 뇌파, 심박 변이, 혈압, 맥박, 코티졸, 혈압 등을 지표로 선정하였다. 전체 피험자의 생리적 반응으로 숲의 스트레스 완화효과를 분석한 결과, 졸참나무숲은 중추신경계, 자율신경계, 내분비계 측면에서 다른 숲에 비하여 높은 스트레스 완화효과를 기대할 수 있다. 편백나무숲은 자율신경계를 제외한 지표에서, 소나무숲은 내분비계와 자율신경계 일부 지표에서 스트레스 완화에 기여할 수 있다. 그러나 소나무숲은 스트레스 완화효과에 있어서 상대적으로 효과가 적다. 고혈압 환자는 효과의 정도 측면에서 소나무숲보다 편백나무숲과 졸참나무숲에서 체류할 때 높은 혈압 강하의 효과를 얻을 수 있다. 당뇨병 환자는 혈당저하의 효과측면에서는 모든 숲이 효과적이나 특히, 졸참나무숲에서 체류하는 것이 높은 효과를 경험할 수 있다.