Journal of Acupuncture Research
- Volume 22 Issue 3
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- Pages.137-144
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- 2005
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
Clinical Study of Heart Rate Variability on Patients with Idiopathic Parkinson's Disease according to Clinical Scale(Hoehn-Yahr stage, UPDRS)
특발성 파킨슨병 환자의 임상척도에 따른 심박변이도의 변화에 대한 연구
- Park, Sang-min (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
- Lee, Sang-hoon (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
- Jung, Ji-cheol (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
- Kim, Kun-hyung (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
- Park, Hi-joon (Department of Acupuncture & Meridian, College of Oriental Medicine, Kyung Hee University) ;
- Lim, Sabina (Department of Acupuncture & Meridian, College of Oriental Medicine, Kyung Hee University) ;
- Chang, Dae-il (Department of Neurology, College of Medicine, Kyung Hee University) ;
- Lee, Yun-ho (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University)
- 박상민 (경희대학교 한의과대학 침구학교실) ;
- 이상훈 (경희대학교 한의과대학 침구학교실) ;
- 정지철 (경희대학교 한의과대학 침구학교실) ;
- 김건형 (경희대학교 한의과대학 침구학교실) ;
- 박히준 (경희대학교 한의과대학 경혈학교실) ;
- 임사비나 (경희대학교 한의과대학 경혈학교실) ;
- 장대일 (경희대학교 의과대학 신경과학교실) ;
- 이윤호 (경희대학교 한의과대학 침구학교실)
- Received : 2005.04.27
- Accepted : 2005.05.14
- Published : 2005.06.20
Abstract
Objective : This study was designed to assess the heart rate variablitv of patients with Parkinson's disease according to Hoehn-Yahr stage. Methods : Subjects were voluntarily recruited by newspapers and internet. All the subjects are confirmed as idiopathic parkinson's disease by a neurologist. The patients were grouped by Hoehn-Yahr(H-Y) stage. Heart rate variability was measured for 5 minutes after 5 minutes' bed rest. Subjects were comprised of 3 groups which were H-Y stage I (n=14), H-Y stage H(n=9), H-Y stage III(n=7). We compared the heart rate variability of each groups by one-way ANOVA test. We also studied the relationship between UPDRS score and Heat rate variability components (SDNN, RMS-SD and TP) by pearson correlation analysis and simple linear regressin analysis Results: Age, duration was matched among groups. SDNN, RMS-SD, TP were significantly decreased as H-Y stage increased(p<0.05). Especially there was significant difference between H-Y stage I and III group(p<0.05). But other components(Heart rate, LF, HF, LF/HF ratio) were not showed significant difference. SDNN, RMS-SD and TP were significantly decreased as UPDRS scores increase(p<0.05). Conclusion : This study suggests that the function of the autonomic nervous system decreases as Parkinson`s disease progresses.
본 저자는 2004년 3월 9일부터 2004년 5월15일까지 경희의료원 침구과 외래를 내원한 특발성 파킨슨병 환자를 대상으로 하여 파킨슨병 증상의 호전도를 판단하는 임상척도인 H-Y stage에 따른 HRV를 관찰한 결과 다음과 같은 결론을 얻었다. 1. 시간영역분석에서 H-Y stage I, II, III 그룹의 SDNN은
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