• 동의신경정신과학회지
• /
• 제15권1호
• /
• pp.197-209
• /
• 2004

Objectives : The purpose of this case-control research was to investigate the effects of acupuncture stimulation on autonomic nervous system for patients with HRV and to find out relationship with anti-stress effects. Methods : The study group consists of 24 patients with self-recognition of stress as the case group, and 20 normal person as the control group by similar age. We measured HRV of case and control groups before acupuncture stimulation, prick acupuncture in Hegu(LI4), Taichong(Liv3), Shenme(H7), Neiguan(P6), Zusanli(S36). After treating for 20 minutes, measurement values of HRV and PSV were compared for pre-acupuncture and post-acupuncture. Results : 1. LF norm, HF norm, LF/HF between the case and control groups were significant different in HRV before acupuncture stimulation in the 1st experiment. 2. HRT, SDNN, SDSD, LF norm, HF norm, and LF/HF of the case group were significant different in HRV after acupuncture stimulation in the 1st experiment. HRT of the case group was significantly different in HRV after acupuncture stimulation in the 1st experiment. 3. LF norm, HF norm, LF/HF of the case group were significant different between the 1st and 2nd experiment in HRV before acupuncture stimulation. 4. LF norm, HF norm, and LF/HF were significant different between the 1st and 2nd experiment in HRV of patients whose symptoms improved. But HRV of patients whose symptoms unimproved didn't show significant difference. Conclusion : The results suggest that acupuncture stimulation is associated with changed activity in the sympathetic and parasympathetic nervous system. Measurement values of HRV is suitable to estimate the activity of automatic nervous system.

• 대한한방부인과학회지
• /
• 제24권4호
• /
• pp.71-84
• /
• 2011

Purpose: To evaluate the correlation of MRS, MENQOL, HRV, Yin-Deficiency Questionnaire and the clinical use of Yin-Deficiency Questionnaire by comparison with MRS, MENQOL, and HRV. Methods: The participants were 21 women(44-58yr) with hot flush who were not currently on hormone therapy. The evaluating index of this trial are MRS, MENQOL, HRV, Yin-Deficiency Questionnaire. Results: The MRS and the MENQOL were significantly correlated with each other. The MRS and the HRV(LF/HF ratio) were significantly correlated with each other. The MENQOL and the HRV(LF/HF ratio) were significantly correlated with each other. The MRS somatic subscale and the Yin-Deficiency Questionnaire were significantly correlated with each other. The MENQOL and the Yin-Deficiency Questionnaire were significantly correlated with each other. The Yin-Deficiency Questionnaire and the HRV(LF/HF ratio) were significantly correlated with each other. Conclusions: The Yin-Deficiency Questionnaire is a valuable tool of oriental medicine for assessment of symptoms. The Yin-Deficiency Questionnaire were significantly correlated with the MRS somatic subscale, the MENQOL and the HRV(LF/HF ratio). Yin-Deficiency Questionnaire could serve as an adequate diagnostic instrument of oriental medicine for menopausal syndrome. Further large-scale study is needed for evaluation of the correlation of these measurements related with Menopausal syndrome and the clinical use of Yin-Deficiency Questionnaire.

• 동의신경정신과학회지
• /
• 제22권4호
• /
• pp.87-100
• /
• 2011

Objectives : This study aims to evaluate the relationship between HRV indices and scores of emotional questionnaires and to find out the effective way to assess patients emotional and physical condition. Methods : We selected 144 patients who had both HRV data and BDI, STAI and STAXI scores on the chart among outpatients from July 2006 to December 2010. The relationship between the scores rated from the questionnaires and HRV indices are analyzed. And the HRV indices of patients included in the top 30 percent group and the bottom 30% group are compared. Results : 1. There were no significant correlations between HRV indices and scores of BDI, STAI and trait anger of STAXI. 2. SDNN and TP of HRV significantly decreased with higher state anger scores of STAXI. The top 30 percent group of state anger had lower SDNN, TP, LF, HF and HRV-index and higher pNN50 than the bottom 30 percent group. 3. RMSSD of HRV significantly decreased with higher anger-in scores of STAXI. The top 30 percent group of anger-in had lower RMSSD than the bottom 30 percent group. Conclusions : HRV can be used to evaluate emotional and physical changes related to state anger and inappropriate anger expression.

• 대한한방부인과학회지
• /
• 제35권3호
• /
• pp.122-136
• /
• 2022

Objectives: The aim of this study is to investigate Heart Rate Variability (HRV) characteristics of patients with primary dysmenorrhea at the menstrual phase. Methods: 7 databases (Pubmed, Cochrane library, CNKI, RISS, KISS, OASIS, ScienceON) were searched for eligible studies published before 2021 December. The studies comparing HRV between patients with primary dysmenorrhea and controls were included. A random-effects model was used to evaluate differences of HRV parameters between patients with primary dysmenorrhea and controls. Results: 4 articles were included in this review based on inclusion and exclusion criteria. SDNN (Standard deviation of NN intervals), RMSSD (Square root of the mean squared difference of successive NN intervals), mean PR (Mean of pulse rate), LF (Low frequency), HF (High frequency), was the most frequently used as HRV parameters. RMSSD was significantly lower in patients with primary dysmenorrhea than controls. There was no statistically significant difference of other HRV parameters between patients with primary dysmenorrhea and controls. Conclusions: This study suggests that parasympathetic activity and overall functions of autonomic nervous system might be decreased in patients with primary dysmenorrhea at the menstrual phase. In the future, well-designed clinical studies using HRV and additional meta-analysis should be conducted to obtain a wealth of information about HRV characteristics of patients with primary dysmenorrhea.

• 원예과학기술지
• /
• 제28권6호
• /
• pp.1066-1071
• /
• 2010

자기보고식 설문평가와 컴퓨터 기반 심박변이도(Heart rate variability, HRV) 분석평가를 통해 원예치료가 우울증 환자의 정서개선에 미치는 효과를 알아보았다. 자기보고식 설문 평가는 정신적 스트레스, 신체적 스트레스, 불안, 우울 등 4가지 평가도구를 사용하였다. HRV 분석평가는 standard deviation of the N-N intervals(SDNN), square root of mean squared difference of successive N-N intervals(RMSSD), total power(TP), low-frequency/high-frequency ratio(LF/HF ratio)의 4개 분석지표를 이용하였다. 동일한 병원 소속 우울증 환자 30명을 대상으로 실험을 수행하였다. 이 가운데 실험군 15명을 대상으로 주 1회씩 12회 원예치료 프로그램을 실시하였고, 대조군에는 실시하지 않았다. 그 결과, 원예치료를 실시 한 실험군의 경우 자기보고식 설문평가는 물론 HRV 분석평가에서도 원예치료 후 우울 정서 개선 효과가 확인되었다. 특히 자기보고식 평가에서는 정신적 스트레스, 불안, 우울 척도에서 통계적으로도 유의한 효과가 나타났으며($p$<0.001), HRV 분석평가의 경우 TP 지표에서 통계적 유의성이 확인되었다($p$<0.05). SDNN, RMSSD, LF/HF ratio 지표 역시 눈에 띄게 호전되었으나 통계적 유의성은 없었다. 비록 HRV의 모든 분석지표들이 통계적 유의성을 나타내지는 않았지만, 이 연구를 통해 HRV 측정으로 원예치료 효과를 객관화된 수치로 제시할 수 있는 가능성을 확인하였다. 또한 주관적 평가와 객관적 평가를 도입한 본 실험 결과 원예치료가 우울증 환자의 심리적, 신체적 재활에 효과적임이 입증되었다.

• 정신신체의학
• /
• 제21권1호
• /
• pp.55-61
• /
• 2013

연구목적 알츠하이머병(Alzheimer's disease, 이하 AD)과 경도 인지 장애(Mild cognitive impairment, 이하 MCI)는 자율신경계를 포함한 여러 신경 기능에 영향을 미친다. 신경정신과적 장애와 심박 변이도(Heart rate variability, 이하 HRV)간의 연관성은 많이 연구되어 왔지만, AD에서 심혈관계 자율신경 기능에 관한 연구는 시행된 바가 적고, 연구 결과도 일관되지 않는다. 이에 본 연구는 HRV의 분석을 통하여 AD, MCI 그리고 정상 대조군에서 자율 신경계의 활성도 차이를 평가하고자 하였다. 방 법 5분 동안 RR 간격의 시간, 주파수 영역 변이도가 26명의 정상 대조군, 22명의 MCI군, 34명의 AD군에서 각각 평가되었다. 그룹 간 차이를 평가하기 위해 일원배치 분산분석(Analysis of variance, ANOVA)이 사용되었으며, MMSE-KC와 HRV 요소 간의 상관관계는 피어슨 상관계수(Pearson's correlation coefficient)로 평가되었다. 결 과 HRV의 시간, 주파수 영역 분석에서 그룹간의 의미 있는 차이는 관찰되지 않았다. 인지 기능 장애 정도와 HRV 간의 상관 관계도 유의하지 않은 것으로 나타났다. 결 론 정상 대조군과 비교하였을 때 MCI, AD군의 HRV 요소는 통계적으로 유의한 차이가 없는 것으로 나타났다. MCI와 AD의 비침습적인 검사 도구로써 HRV가 사용되기 위해서는 후속적인 연구가 필요할 것으로 생각된다.

• Clinical and Experimental Pediatrics
• /
• 제59권11호
• /
• pp.432-439
• /
• 2016

Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The advent of molecular diagnostics to detect respiratory viruses has provided new insights into the role of human rhinovirus (HRV) infections in the pathogenesis of asthma. However, it is still unclear whether HRV infections cause asthma or if wheezing with HRV infection is simply a predictor of childhood asthma. Recent clinical and experimental studies have identified plausible pathways by which HRV infection could cause asthma, particularly in a susceptible host, and exacerbate disease. Airway epithelial cells, the primary site of infection and replication of HRV, play a key role in these processes. Details regarding the role of genetic factors, including ORMDL3, are beginning to emerge. This review discusses recent clinical and experimental evidence for the role of HRV infection in the development and exacerbation of childhood asthma and the potential underlying mechanisms that have been proposed.

• 대한의용생체공학회:학술대회논문집
• /
• 대한의용생체공학회 1998년도 추계학술대회
• /
• pp.137-138
• /
• 1998

The purpose of this study is to evaluate the HRV(Heart Rate Variability) to visual and auditory stimulation. We analysed psychological effect and HRV of music, light, and music with light. The results show that HRV pattern is significantly related to the psychological effect, and HRV spectrum is useful to extract more information when various stimulation are presented.

• 대한한방부인과학회지
• /
• 제24권4호
• /
• pp.186-193
• /
• 2011

Purpose: This study was performed to find correlations between Edema Index and Heart Rate Variability(HRV) conducted in early postpartum period. Methods: 17 postpartum women were participated in this study which was conducted with Inbody 720(Biospace Co. Ltd.) and SA-6000(Medicore Co. Ltd.). Edema Index(Extra Cellular Water/Total Body Water) was calculated after body composition analysis and HRV result(TP, VLF, LF, HF, HF norm, LF norm, LF/HF ratio) was analysed within a week after delivery. Results: There was no significant correlations between Edema Index and HRV results in time domain analysis. also Edema Index and TP, LF, HF, LF/HF ratio have no significant correlations in frequency domain analysis. but only VLF data has significance compared with Edema Index. Conclusions: It can be suggested that VLF results analysed by HRV can be useful reference estimating postpartum edema especially occurs in early postpartum period.

• 설비공학논문집
• /
• 제20권1호
• /
• pp.26-34
• /
• 2008

Heat recovery ventilator(HRV) is recommended to improve indoor air quarlity (IAQ) and energy conservation in apartment houses. Recently, in Korea, HRV is produced from many manufacturers. However, there have been not so many experiences to apply HRV in apartment houses and verification on the performance such as heat exchange efficiency, carry-over rate, internal leakage, etc. have not been carried out sufficiently. So in this study, fan performance, heat exchange efficiency, air leakage, internal exhaust leakage, external leakage and sound level of HRV were examined for selected HRV models under domestic and international standard. Results of performance test, there were need to improve latent heat exchange efficiency and sound level of HRV.