• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.118-118
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• 2012

Cryopump는 반도체 임플란타 공정, OLED분야, 신소재 개발, 표면분석 및 처리, 의료분야, 입자가속기, 핵융합 등 다양한 진공분야에 응용되는 고진공용 극저온펌프이다. 특히 향후로의 산업구조는 디스플레이, 반도체, IT 산업분야로 집중 재편될 것이기에, 이에 따른 핵심제조장비인 고진공 펌프의 수요가 급증할 것으로 판단된다. 그리고 이를 위한 핵심부품과 장비들의 국산화가 시급한 실정이다. 기술적인 측면에서 보자면 GVT는 미국의 Varian과 일본Ebara의 Cryopump 제조기술을 원천으로 한 회사로써 현재는 국내 유일의 G-M 냉동기와 Cryopump 제조기술을 보유한 업체이다. 그리고 최근 오랫동안 정체되었던 관련 기술을 발전시켜 최적화된 한국형 G-M 냉동기 및 이를 장착한 다양한 사이즈의 고성능 Cryopump를 출시하게 되었다. 가장 큰 수확은 Cryopump의 성능을 크게 향상시켰으며 무엇보다 고객맞춤형으로 디자인할 수 있을 정도의 기술력을 확보하게 되었다는 점이다. Cryopump의 성능은 장착되는 Cryocooler (G-M냉동기)의 성능과 밀접한 관련이 있기 때문에 일차로 Cryocooler의 성능을 개선하고 이차로 이를 장착한 Cryopump의 성능을 개선하였다. 본 연구는 일차로 진행된 HP Series 2단 Cryocooler 4가지 모델 중 가장 범용인 HPM 모델과 HPS모델에 대한 제작과 성능시험에 관한 것이다. 이는 각각 기존의 ICP Series 펌프에 장착되던 Expander 535 모델 및 Expander 855 모델에 대한 설계 최적화의 결과물로써 내용은 Cryocooler에 대한 'Typical Performance Test(1st STG와 2nd STG의 온도가 각각의 Stage에 인가되는 Heat Load에 의해 그물망 형태의 그래프가 되도록 수행하는 시험법)'의 절차를 따라 수행되었다. HPM Cryocooler의 성능은 2nd STG Temp. 20K와 1st STG Temp. 80K를 Heat Load기준으로 하였을 경우, 각각 8.2W, 55.0W의 성능을 나타내었고 HPS Cryocooler의 성능은 2nd STG Temp. 20K 와 1st STG Temp. 72K를 Heat Load기준으로 하였을 경우, 각각 14.0W, 90.0W의 성능을 나타내었다. 1st STG Temp.를 72K로 정한 이유는 Power Supply의 용량 한계로 인해 90W이상의 Heat Load를 인가할 수 없었기 때문이다. 만약 성능 그래프의 경향성을 고려하여 1st STG Temp. 80K로 가정한다면, 각각 약 13W, 100W 정도의 성능을 가질 것으로 추정된다. 단, 본 시험에 사용된 Compressor는 GVT의 HC80Plus 모델로 내부에는 Helium용 5HP급 Scroll Type의 Compressor가 장착되어 있으며, 봉입압력 250Psig에 저압 100Psig기준, 65scfm의 유량을 가지는 압축기이다. 압축기와 Cryocooler의 조합은 1:1이었고 시험방법은 Cryocooler에 대한 GVT 자체규정에 따라 진행되었으며 밤과 낮 및 공장전체의 부하변동에 따른 냉각수 온도변화에 따른 펌프의 성능변화는 고려되지 않았다.

• Microbiology and Biotechnology Letters
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• v.31 no.2
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• pp.103-110
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• 2003

The regulation of pyrimidine nucleotide synthesis has been proved to be controlled by a regulatory protein PyrR-mediated attenuation in the Gram-positive bacteria. After several bacterial genome sequencing projects, we have discovered the PyrR orthologues in the databases for Haemophilus influenzae and Synechocystis and sp. PCC6803 genome sequences. To investigate whether these PyrR orthologue proteins regulate pyrimidine nucleotide synthesis as well as the cases of Bacillus, the PyrR regions of each strains were amplified by PCR and cloned with pUC19 or T-vector in Escherichia coli and with a shuttle vector pHPS9 for E. coli and B. subtilis. For the regulation test of the PyrR orthologues, the aspartate-transcarbamylase (ATCase) assay was carried out. From the results of the ATCase assay, it was confirmed that Synechocystis sp. PCC6803 could not restore by pyrimidines to a B. subtilis, PyrR but H. influenzae PyrR could. For Purification of PyrR orthologue proteins, PyrR orthologue genes were cloned into the expression vector (pET14b). Over-expressed product of PyrR orthologue genes was purified and analyzed by the SDS-PACE. The purified PyrR orthologue proteins from H. influenzae and Synechocystis sp. PCC6803 turned out to be molecular mass of 18 kDa and 21 kDa, respectively. The result of uracil phosphoribosyl transferase (UPRTase) assay with purified PyrR orthologue proteins showed that H. influenzae PyrR protein only has UPRTase activity. In addition, we could predict several regulatory mechanisms that PyrR orthologue proteins regulate pyrimidine de novo synthesis in bacteria, through phylogenetic analysis for PyrR orthologue protein sequences.

• Journal of Radiation Protection and Research
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• v.42 no.2
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• pp.83-90
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• 2017

Background: Different cases exist in the measurement of thyroid radiobioassays owing to the individual characteristics of the subjects, especially the potential variation in the counting efficiency. An In situ Object Counting System (ISOCS) was developed to perform an efficiency calibration based on the Monte Carlo calculation, as an alternative to conventional calibration methods. The purpose of this study is to evaluate the applicability of ISOCS to thyroid radiobioassays by comparison with a conventional thyroid monitoring system. Materials and Methods: The efficiency calibration of a portable high-purity germanium (HPGe) detector was performed using ISOCS software. In contrast, the conventional efficiency calibration, which needed a radioactive material, was applied to a scintillator-based thyroid monitor. Four radioiodine samples that contained $^{125}I$ and $^{131}I$ in both aqueous solution and gel forms were measured to evaluate radioactivity in the thyroid. ANSI/HPS N13.30 performance criteria, which included the relative bias, relative precision, and root-mean-squared error, were applied to evaluate the performance of the measurement system. Results and Discussion: The portable HPGe detector could measure both radioiodines with ISOCS but the thyroid monitor could not measure $^{125}I$ because of the limited energy resolution of the NaI(Tl) scintillator. The $^{131}I$ results from both detectors agreed to within 5% with the certified results. Moreover, the $^{125}I$ results from the portable HPGe detector agreed to within 10% with the certified results. All measurement results complied with the ANSI/HPS N13.30 performance criteria. Conclusion: The results of the intercomparison program indicated the feasibility of applying ISOCS software to direct thyroid radiobioassays. The portable HPGe detector with ISOCS software can provide the convenience of efficiency calibration and higher energy resolution for identifying photopeaks, compared with a conventional thyroid monitor with a NaI(Tl) scintillator. The application of ISOCS software in a radiation emergency can improve the response in terms of internal contamination monitoring.

• Journal of the Korean Ceramic Society
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• v.51 no.5
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• pp.477-480
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• 2014

An $Al_2O_3$-CuO-ZnO (ACZ) precursor powder was synthesized by a facial sol-gel process using a nonionic surfactant span 80 as the chelating agent to improve the surface area and morphology. When creating a hydrogen membrane, several kinds of properties are required, such as easy dissociation of hydrogen molecules, fast hydrogen diffusion, high hydrogen solubility, and resistance to hydrogen embrittlement. ACZ-Ni composite membranes (cermet) were prepared with this precursor and pure Ni powder via the hot press sintering (HPS) method. The ACZ powder was characterized by XRD, BET, and FE-SEM. Hydrogen permeation experiments were performed by Sievert's type of hydrogen permeation membrane equipment. The hydrogen permeability of ACZ/Ni 10 wt% and ACZ/Ni 20 wt% was obtained as 7.2 and $10molm^{-2}s^{-1}$ at RT, respectively. These values of the corresponding membranes were slightly increased with increasing pressures.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.6
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• pp.899-905
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• 2001

This paper presents a triple-mode dielectric resonator far low loss and simple structure filter design. The BPF(Band Pass Filter) was designed using HFSS simulation results an4 fabricated using proposed resonators. The filter (3-stage BPF) has an insertion loss of about 0.9 dB at the center frequency of 1.93 GHz and a 3 dB bandwidth of about 25 MHz. If more complex characteristic is required, slot coupling between resonators can be used. Especially, the proposed BPF can be applied to the next generation mobile communication IMT-2000 system.

• Journal of Sensor Science and Technology
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• v.27 no.2
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• pp.126-131
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• 2018

Unlike the hydraulic power steering (HPS) system, which operates by the high pressure of a fluid obtained from the engine power, the motor-driven power steering (MDPS) system uses an electric motor to steer the wheel without consuming engine power. To steer the wheel with an electric motor, a worm wheel and a worm gear rotating between the steering shaft and motor are required. Any imperfection during the construction of an MDPS system or in a composing part creates noise and vibration, which can be sensed by a driver. To solve the noise and vibration problems, each part must be designed to not resonate with other parts. In this work, we developed the measurement and analysis systems to obtain the noise and the vibration of an automobile MDPS system. A signal analyzer was equipped with a 96 kHz, 24-bit ADC and a 150 MHz digital signal processor. The predetermined threshold value of the vibration in the MDPS system was used to determine the pass/fail, and the results were displayed on the screen. Our system can be used in the fabrication line to swiftly determine any imperfections in the MDPS system construction.

• Analytical Science and Technology
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• v.24 no.2
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• pp.105-112
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• 2011

Syntheses and property analysis of hydropolysilanes were studied. Those hydropolysilanes can be utilized as precursors for amorphous silicon and polycrystallline silicon for the purpose of the solar cell and the thin film transister for the next generation's semiconductors. Most important characteristics of this study are to find optimized conditions for the synthesis and property analysis of soluble hydropolysilanes. Also the possibility of pyrolytic conversion to amorphous and polycrystalline silicon was investigated.

• Journal of Environmental Health Sciences
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• v.38 no.4
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• pp.351-359
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• 2012

Objectives: This study was conducted in order to investigate the specific correlation between physicochemical properties and bioactivity in ecdysteroids found in living organisms. Methods: The examined steroidal compounds were classified into three groups according to their relevance to ecdysone activity. Each compound molecule was completely drawn to automatically calculate its physicochemical parameters and docked against 20-hydroxyecdysone to calculate the total distance. Electronic charge distribution was also observed for each molecule. All procedures were conducted using a computational chemistry program. Results: Ecdysone agonists showed different ranges of parameter values, such as log P, hydrophilic-lipophilic balance (HLB), solubility parameter (SP), hydrophilic surface (HPS), hydrogen bond (HB) and Kappa 2, when compared with antagonists and steroids without ecdysone activity. They also showed a similar electronic charge distribution that is significantly different from the electron charge distribution of antagonists and steroids without ecdysone activity. The total distance values of agonists, estimated by docking them with 20-hydroxyecdysone, were relatively small but showed no correlation with binding affinity with receptor ligand. Conclusions: These results suggest that physicochemical properties such as steric and electronic effects, hydrophobicity and hydrogen bonding may operate in combination to determine the binding activity of ecdysteroids to the receptor protein.

• The Journal of Korean Academic Society of Nursing Education
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• v.18 no.1
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• pp.14-24
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• 2012

Purpose: This study was conducted to identify the effect of simulation-based education relevant to the care of patients with acute renal failure (ARF) for third-year nursing students. Methods: This study was a non-equivalent control pre-posttest design. Based on the clinical situation scenarios pertaining to patients with ARF, a simulation-based learning module was developed using Human Patient Simulator version 6 (HPS6) manufactured by Medical Education Technologies Inc. The pretest was conducted so as to evaluate the difference in prior knowledge and clinical competence between two groups. The control group consisted of 91 students during the 2010 academic year and the experimental group consisted of 94 students during the 2011 academic year. Data were analysed using SPSS/win 10.1. Results: In the experimental group, knowledge related to care for ARF patients was not significantly increased; however, clinical competence improved significantly for the experimental group. Conclusion: In conclusion, the simulation-based education program was effective in contributing towards the development of clinical competence. Increased development of clinical competence is vital for today's clinical environment where nursing professionals need the necessary knowledge, thinking, and performance skills to meet the needs of the hospital and their patients.

• The Journal of Korean Society of Virology
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• v.29 no.1
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• pp.23-31
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• 1999

Hantavirus is a genus of the Bunyaviridae family causing two serious diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Puumala virus is a member of hantavirus originally found in Europe, and its natural reservoir is Clethrionomys glareolus. It is also associated with the human disease nephropathia epidemica, a milder form of HFRS. To identify the hantaviruses in bats, bats were collected from Jeong-Sun, Won-Joo, Chung-Ju and Hwa-Cheon area in Korea, and nested RT-PCR was performed with serotype specific primer from M segment. Interestingly, Puumala virus was detected in bats (Rhinolophus ferrum-equinum) only from Won-Joo. The 327 bp nested RT-PCR product, was sequenced. The sequence database search indicates that the sequence is homologous to the published sequence of Puumala viruses. The sequence similarities were ranged from 71% to 97%. The highest sequence similarity was 97% with Puumala virus Vranicam strain, and the lowest was 71% with Puumala virus K27 isolate. Puumala virus Vranicam strain was isolated from a bank vole (Clethrionomys glareolus) in Bosnia-Hercegovina. Puumala virus K27 was isolated from human in Russia. This analysis confirms that bats (Rhinolophus ferrum-equinum) in Korea are natural reservoir of Puumala virus.