• 대한정형외과스포츠의학회지
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• 제1권1호
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• pp.15-20
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• 2002

목적: 스포츠손상에의한비구순파열환자에서진단및치료에대해고찰해보고자하였다. 대상및방법: 1995년3월부터2000년1월까지스포츠손상후발생한고관절통으로본원에내원한환자에서비구순파열로진단된15예를대상으로하였다. 원인별로달리기5예, 격투기3예, 에어로빅3예, 수영2예, 등산1예, 자전거 1예등이었다. 남자가6명, 여자가9명이었고, 나이는 평균41세였다. 모든 환자는6개월간격으로 추시하였고, 보존적 치료를 시행한 경우최소2년 이상 투약 및 증세관찰을 하였고, 관절경적 수술을 시행한6예에서 수술 전, 수술 후 6개월과 12개월에 Harris Hip Score (이하HHS)를측정하였고, JOA pain scoring system에의해결과를평가하였다. 결과: 보존적치료를 시행한9예에서 HHS는 평균 15점 향상되었고, 그중 4예는 1단계의 통증 지수 향상이 있었는데, 이들 모두Czerny 분류상type IA였다. 관절경적수술을 시행한6예에서수술후 HHS는 32점향상되었고, 6예모두에서2단계이상의통증지수향상이관찰되었다.결론: 스포츠손상환자에서급,만성고관절통을호소하는경우비구순파열은반드시감별진단되어야하며, 이학적검사상의심이될경우자기공명관절조영술을이용한진단이유용할것으로사료된다. 확진이된경우관절경을이용한파열된비구순의변연절제술이효과적인치료방법으로생각된다.

• 한국진공학회지
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• 제18권2호
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• pp.108-115
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• 2009

150 주기의 InAs/GaSb (8/8-ML) 제2형 응력초격자 (SLS)를 활성층에 탑재한 초격자 적외선검출소자 (SLIP) 구조를 MBE 방법으로 성장하고, 직경 $200{\mu}m$의 개구면을 가지는 SLIP 개별소자를 시험 제작하였다 고분해능 투과전자현미경 (TEM) 이미지의 휘도분포와 X선회절 (XRD) 곡선의 위성피크의 분석 결과는 SLS 활성층은 균일한 층두께와 주기적 응력변형을 유지하는 급격한 계면의 초격자임을 입증하였다. 흑체복사 적외선 광원을 이용하여 측정한 입사파장 및 인가전압에 따른 반응도 (R)와 검출률 ($D^*$)로부터, 차단파장은 ${\sim}5{\mu}m$이고 최대 R과 $D^*$ ($\lambda=3.25{\mu}m$)는 각각 ${\sim}10^3mA/W$ (-0.6 V/13 K)와 ${\sim}10^9cm.Hz^{1/2}/W$ (0 V/13 K)임을 보였다. 반응도의 온도의존성으로부터 분석한 활성화에너지 275 meV는 광반응 과정에 개입되어 있는 가전대 및 전도대 부준위 사이의 에너지 간격 (HH1-C)과 잘 일치하였다.

• 약학회지
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• 제58권4호
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• pp.255-261
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• 2014

Poly-pharmacy has been on the rise because of aging of population and chronic disease. Most of drug metabolism happens in the liver by CYP isozymes and the metabolism by CYP450 enzymes. The Cytochrome P450 (CYP) is a superfamily of enzymes that catalyzes the oxidations of many endogenous and exogenous compounds. Primary human Hepatocytes (HH) are considered as the gold standard model for In vitro drug interaction studies. However, there are several limitations (cost, limited life span) for using HH cells. HepaRG cells are being used as a possible alternative. HepaRG cells were cultured in William E medium containing the positive control inducers (1A2: 10, 25, 50 ${\mu}M$ omeprazole, 2C9 and 2C19: 10 ${\mu}M$ rifampin, 3A4: 10, 25, 50 ${\mu}M$ rifampin) at $37^{\circ}C$, 5 % $CO_2$ in a humidified atmosphere. This study was to evaluate the induction of CYP isozymes (1A2, 2C9, 2C19 and 3A4) using LC-MS/MS. We evaluated the potential induction ability of Bosentan, as a drug of pulmonary artery hypertension, in HepaRG cells. For reference, dose of the Bosentan is determined to the basis of the $C_{max}$ (835 mg/ml) value. The enzyme activity demonstrated that CYP2C9 and 3A4 were induced up to 20 times by Bosentan. Like as In vivo, the enzyme activity of CYP2C9 and CYP3A4 is significantly induced in a dose-dependent by Bosentan.

• 한국전자파학회논문지
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• 제23권10호
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• pp.1204-1211
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• 2012

본 연구에서는 위성 SAR(Synthetic Aperture Radar) 시스템 검 보정을 위한 기반기술 습득을 위해 수행된 X-밴드 대역 능동전파반사기를 이용한 실제 위성 SAR 방사 패턴 측정 및 분석에 관한 연구 결과를 선보인다. 실험에 사용된 자체 설계/제작된 능동전파반사기는 최대 63.1 dBsm의 레이더 단면적(RCS: Radar Cross Section)을 가지며, 외부 수신 장치를 이용한 수신 기능을 포함한다. 위성 SAR 시스템의 방사 패턴 측정 정확도를 높이기 위해 동일한 운용 모드의 위성 SAR(COSMO-SkyMed 2/3호, hh-편파, strip-map himage mode, 해상도 3 m) 시스템을 이용하였으며, 이때, SAR 영상 데이터 내 능동전파반사기의 RCS 크기 분석을 병행하여 측정 결과의 신뢰도를 교차분석하였다. 수신된 신호로부터 추출된 위성 SAR 시스템의 방위각 방향 방사 패턴 특성은 각각 HPBW(half-power beamwidth) $0.352^{\circ}$, FNBW(first-null beamwidth) $0.691^{\circ}$, PSLR(peak to side lobe ratio) 11.17 dB이다.

• 대한신경집중치료학회지
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• 제11권2호
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• pp.93-101
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• 2018

Background: At most centers, general anesthesia (GA) has been preferred for endovascular treatment (EVT) of ruptured intracranial aneurysms (RIAs). In this study, we analyzed procedural results, clinical outcomes, and follow-up angiographic findings for patients undergoing EVT for RIA under local anesthesia (LA) with conscious sedation (CS). Methods: We retrospectively evaluated 308 consecutive patients who underwent EVT for RIAs at a single institution between June 2009 and February 2017. EVT under LA with CS was considered for all patients with aneurysmal subarachnoid hemorrhage, regardless of Hunt and Hess (HH) scale score. Results: EVT was performed for 320 aneurysms in 308 patients with subarachnoid hemorrhages. The mean patient age was $55.5{\pm}12.6$ years. Moderate (III) and poor (IV, V) HH grades were observed in 75 (24.4%) and 77 patients (25%), respectively. Complete occlusion immediately after EVT was achieved for 270 (84.4%) of 320 aneurysms. Thromboembolic complications and intraprocedural ruptures occurred in 25 (7.8%) and 14 cases (4.3%), respectively. The morbidity rate at discharge (as defined by a modified Rankin scale score of 3 or greater) was 27.3% (84/308), while the mortality rate was 11.7% (36/308). Follow-up angiographic results were available for 210 (68.1%) of 308 patients. Recanalization was observed in 64 (29.3%) of 218 aneurysms in 210 patients. Conclusion: Based on our experience, EVT for RIAs under LA with CS was feasible, regardless of the clinical grade of the subarachnoid hemorrhage. Complication rates and follow-up angiographic results were also comparable to those observed when GA was used to perform the procedure.

• 한국세라믹학회지
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• 제43권4호
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• pp.242-246
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• 2006

[ ${\alpha}-Al_2O_3$ ] nanopowders were fabricated by the thermal decomposition and synthetic of Ammonium Aluminum Carbonate Hydroxide (AACH). Crystallite size of 5 to 8 nm were fabricated when reaction temperature of AACH was low, $8^{\circ}C$, and the highest $[NH_4{^+}][AlO(OH)_n{(SO_4){^-}}_{3-n/2}][HCO_3]$ ionic concentration to pH of the Ammonium Hydrogen Carbonate (AHC) aqueous solution was 10. The phase transformation fem $NH_4Al(SO_4)_2$, rhombohedral $(Al_2(SO_4)_3)$, amorphous-, ${\theta}-,\;{\alpha}-Al_2O_3$ was examined at each temperature according to the AACH. A Time-Temperature-Transformation (TTT) diagram for thermal decomposition in air was determined. Homogeneous, spherical nanopowders with a particle size of 70 nm were obtained by firing the 5 to 8 m crystallites, which had been synthesized from AACH at pH 10 and $8^{\circ}C,\;at\;1150^{\circ}C$ for 3 h in air.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 1999년도 Proceedings of International Symposium on Remote Sensing
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• pp.468-473
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• 1999

This study was carried out to assess the use of RADARSAT data which is C-band with HH polarization for the rice growth monitoring in Korea. Nine time-series data were taken by shallow incidence angle (standard beam mode 5 or 6) during rice growing season. And then, backscatter coefficient ($\sigma$$^{\circ}$) were extracted by calibration process for comparing with rice growth parameters such as plant height leaf area index(LAI), and fresh and dry biomass. Field experimental data concerned with rice growth were collected 8 times for the ground truth at the study area, Tangjin, Chungnam, Korea. At the maximum vegetative stage of rice, backscatter coefficients were the highest at the flooded rice field ranging from -4.4dB~-3.1dB. The temporal variation of backscatter coefficient($\sigma$$^{\circ}$) in rice field was significant in this study Backscatter coefficient ($\sigma$$^{\circ}$) of rice field was a little bit lower again after heading stage. This results show RADARSTA data is promising for rice monitoring.

• Asian-Australasian Journal of Animal Sciences
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• 제19권7호
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• pp.938-942
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• 2006

Genetic diversity of Magra - a lustrous carpet wool breed of India, was investigated by means of 25 ovine microsatellite markers proposed by the Food and Agriculture Organization and the International Society for Animal Genetics (FAO-ISAG). All used microsatellites amplified well and exhibited polymorphisms. A wide range of genetic variability was observed as allele number from 3 (BM6506, OarCP20) to 10 (CSSM31), observed heterozygosity from 0.200 (BM6506) to 0.947 (OarHH35), expected heterozygosity from 0.368 (CSSM47) to 0.864 (BM1314) and Polymorphism Information Content (PIC) from 0.347 (CSSM47) to 0.849 (BM1314). This supported the utility of these microsatellite loci in the measurement of genetic diversity indices in Indian sheep too. Various average genetic variability measures viz., allele diversity (5.7), observed heterozygosity (0.597), expected heterozygosity (0.694) and mean PIC (0.648) values showed high genetic variability despite accumulated inbreeding as reflected by the high average inbreeding coefficient ($F_{IS}=0.159$) due to the unequal sex ratio of the breeding animals.

• Journal of Korean Neurosurgical Society
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• 제60권3호
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• pp.294-300
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• 2017

Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open craniotomy or endoscopy, stereotactic approaches with radiosurgery and gamma knife surgery or radiofrequency thermos-coagulation, and laser ablation have been introduced. Topographical dimension and the surgeon's preference are key factors for treatment modalities. Endoscopic disconnection has been one of the most favorable options performed in treating HHs. Here we discuss presurgical evaluation, patient selection, surgical procedures, and complications.

• 한국지구과학회:학술대회논문집
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• 한국지구과학회 2010년도 춘계학술발표회 논문집
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• pp.133-133
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• 2010

인공위성 SAR센서는 기존 산란계 해상풍 자료의 낮은 해상도로 인한 여러 한계를 극복함으로써 다양한 해양연구에 있어 필요성과 활용영역이 넓어지고 있다. 이러한 추세에 따라 전세계적으로 다파장 SAR 센서들이 운용 또는 발사 예정에 있음에도 불구하고 현재까지 한반도 주변해에 대한 SAR 해상풍 산출 연구는 C밴드에만 한정되어왔다. 본 연구에서는 L밴드 해상풍 추출알고리즘을 적용하여 L밴드 SAR 영상으로부터 한반도 주변해의 해상풍을 추출하고 산란계 해상풍 자료와 비교 분석을 통해 정확도 특성을 제시하고자 하였다. 2007년 8월 우리나라 동해 지역을 관측한 L밴드 ALOS PALSAR 영상에 대해 L밴드 HH편광 GMF 알고리즘을 적용하여 해상풍을 산출하였다. 산출 해상풍은 동일시점의 산란계 QuikSCAT 자료와 공간적으로 유사한 패턴을 보였으며 두 자료 간의 풍속오차는 3.45m/s로 나타났다. 연구 해역과 같이 강한 바람 범위에서는 산출 해상풍 간의 차이가 크게 나타나며 풍향으로 인한 오차특성이 보인다. 특히 풍속의 경우, 산란계 해상풍이 중간바람 범위에 집중된 것에 비해 L밴드 SAR 산출 해상풍은 강한 바람 범위까지 포함하는 넓은 풍속값 범위를 나타냈다.