• Title/Summary/Keyword: HESS

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Studies on Pythium spp. in Korea -(I) Preliminary taxonomic and physiological studies- (한국(韓國)의 Pythium spp. 에 관(關)한 연구(硏究) -(I) 분류(分類) 및 생화학적(生理學的) 기초연구(基礎硏究)-)

  • Lee, Eung-Kwon;Lee, Young-Hee;Yoo, Jae-Dang;Long, Peter G.
    • The Korean Journal of Mycology
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    • v.3 no.2
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    • pp.7-12
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    • 1975
  • Three species of Pythium previously not recorded in Korea were found during 1975. Pythium spinosum Sawada was isolated from diseased cabbage seedlings, P. myriotylum Dreschl. was isolated from kidney bean and P. butleri Subramanium from cucumber, spinach, red bean and radish. Pathogenicity of isolates of P. butleri and P. myriotylum was confirmed in pathogenicity tests but P. spinosum appeared to be non-pathogenic. Several isolates failed to sporulate satisfactorily on cornmeal agar and some produced degenerate oogonia after sub-culturing on this medium. Sunflower seed agar was found to be a suitable alternative medium. The validity of previous records of P. debaryanum Hess in Korea is discussed.

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Treatment Patterns, Costs, and Survival among Medicare-Enrolled Elderly Patients Diagnosed with Advanced Stage Gastric Cancer: Analysis of a Linked Population-Based Cancer Registry and Administrative Claims Database

  • Karve, Sudeep;Lorenzo, Maria;Liepa, Astra M;Hess, Lisa M;Kaye, James A;Calingaert, Brian
    • Journal of Gastric Cancer
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    • v.15 no.2
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    • pp.87-104
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    • 2015
  • Purpose: To assess real-world treatment patterns, health care utilization, costs, and survival among Medicare enrollees with locally advanced/unresectable or metastatic gastric cancer receiving standard first-line chemotherapy. Materials and Methods: This was a retrospective analysis of the Surveillance, Epidemiology, and End Results-Medicare linked database (2000~2009). The inclusion criteria were as follows: (1) first diagnosed with locally advanced/unresectable or metastatic gastric cancer between July 1, 2000 and December 31, 2007 (first diagnosis defined the index date); (2) ${\geq}65$ years of age at index; (3) continuously enrolled in Medicare Part A and B from 6 months before index through the end of follow-up, defined by death or the database end date (December 31, 2009), whichever occurred first; and (4) received first-line treatment with fluoropyrimidine and/or a platinum chemotherapy agent. Results: In total, 2,583 patients met the inclusion criteria. The mean age at index was $74.8{\pm}6.0years$. Over 90% of patients died during follow-up, with a median survival of 361 days for the overall post-index period and 167 days for the period after the completion of first-line chemotherapy. The mean total gastric cancer-related cost per patient over the entire post-index follow-up period was United States dollar (USD) $70,808{\pm}56,620$. Following the completion of first-line chemotherapy, patients receiving further cancer-directed treatment had USD 25,216 additional disease-related costs versus patients receiving supportive care only (P<0.001). Conclusions: The economic burden of advanced gastric cancer is substantial. Extrapolating based on published incidence estimates and staging distributions, the estimated total disease-related lifetime cost to Medicare for the roughly 22,200 patients expected to be diagnosed with this disease in 2014 approaches USD 300 millions.

Super-Cavitating Flow Problems about Two-Dimensional Symmetric Strut (2차원 대칭 스트럿 주위의 초월 공동 유동 문제의 해석)

  • Y.G.,Kim;C.S.,Lee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.27 no.4
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    • pp.15-26
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    • 1990
  • This paper describes a potential-baoed panel method formulated for the analysis cf a supercavitating two-dimensional symmetri strut. The method employs normal dipoles and sources distributed on the foil and cavity surfaces to represent the potential flow around the cavitating hydrofoil. The kinematic boundary condition on the wetted portion of the foil surface is satisfied by requiring that the total potential vanish in the fictitious inner flow region of the foil, and the dynamic boundary condition on the cavity surface is satisfied by requiring that the potential vary linearly, i.e., the tangential velocity be constant. Green's theorem then results in a potential-based integral equation rather than the usual velocity-based formulation of Hess & Smith type, With the singularities distributed on the exact hydrofoil surface, the pressure distributions are predicted with improved accuracy compared to those of the linearized lifting surface theory, especially near the leading edge. The theory then predicts the cavity shape and cavitation number for an assumed cavity length. To improve the accuracy, the sources and dipoles on the cavity surface are moved to the newly computed cavity surface, where the boundary conditions are satisfied again. This iteration process is repeated until the results are converged.

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Design of an Off Grid type High efficiency Solar charging system Using MATLAB/Simulink (MATLAB/Simulink를 이용한 오프그리드형 고효율 태양광 충전 시스템 설계)

  • Gebreslassie, Maru Mihret;kim, Min;Byun, Gi-sig;Kim, Gwan-hyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.05a
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    • pp.735-737
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    • 2017
  • An Off grid or remote solar electric systems are an energy supply to our home or to our companies without the utility of Grid at all. Off grid solar systems are very important for those who live in remote locations especially for developing countries where getting the electric grid is extremely expensive, inconvenient or for those who doesn't need to pay a monthly bill with the electric bill in general. The main critical components of any solar power system or renewable energy harvesting systems are the energy storage systems and its charge controller system. Energy storage systems are the essential integral part of a solar energy harvesting system and in general for all renewable energy harvesting systems. To provide an optimal solution of both high power density and high energy density at the same time we have to use hybrid energy storage systems (HESS), that combine two or more energy storage technologies with complementary characteristics. In this present work, design and simulation we use two storage systems supercapacitor for high power density and lithium based battery for high energy density. Here the system incorporates fast-response supercapacitors to provide power to manage solar smoothing and uses a battery for load shifting. On this paper discuss that the total energy throughout of the battery is much reduced and the typical thermal stresses caused by high discharge rate responses are mitigated by integrating supercapacitors with the battery storage system. In addition of the above discussion the off grid solar electric energy harvesting presented in this research paper includes battery and supercapacitor management system, MPPT (maximum power point tracking) system and back/boost convertors. On this present work the entire model of off grid electric energy harvesting system and all other functional blocks of that system is implemented in MATLAB Simulink.

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Wortschatzarbeit in der Wortbildung und ihre didaktische $Vorschl\"{a}ge$ (조어론에 있어서의 어휘연습과 교수법 제언)

  • Jang Ki-Sung;Jung Hyun-Sook
    • Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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    • v.3
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    • pp.233-252
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    • 2001
  • 1970년이래 외국어학습 및 교수법에 있어서 어휘에 관련된 문제들에 많은 관심과 그 중요성이 인식되고있다. 특히 Fleischer/Buz (1992)등에 의한 당해 영역의 연구물 뿐 아니라, 전문서적 및 어학 자료(교재)등에서도 이러한 중요성이 강조되어 왔음을 알 수 있다. Fleischer등은 조어규칙의 개념과 조어모델을 규정하는 근거들로 생산성 Produktivitat, 용인성 Akzeptabilitat, 조어참여성 Aktivitat등 중요한 매개요인으로 간주하고 있으며 $G\"{o}tze/ Hess-Luttich$ (1999)등의 학자들은 어휘체계에서 두 개 이상의 구성성분들이 결합하여 당해 시대의 시대정신이나 시대상에 부합되는 신조 어휘들을 생성하며, 또한 그 사회의 정보화와 기술화에 이바지하며, 이를 통해서 전문어의 생산력을 한층 높혀 주는 통로로 작용함을 주장한바 있다. 본고에서는 조어론의 이러한 기본원리나 개념들에 입각하여 독일어 수업에서 목표어의 습득에 관여적인 역할을 수행하는 조어모델, 즉 합성어와 파생어를 형용사와 명사의 층위에서 구체적으로 분석하고 기술했다. 예컨데, 합성어에 있어서 접두사와 접미사, 조어의 유형 가운데 축약어, 그리고 외래어 기저와 고유어 접미사 및 접두사, 고유어기저와 외래어접미사(접두사) 뿐만 아니라, 의미론적 관점에서 본 합성어의 형태, 합성 연결소의 형태와 기호의 사용, 명사적 파생어에서 고유어접미사(접두사), 축약조어와 축약어 단어형성, 형용사조어의 특성, 명시적파생 가운데 고유어(외래어) 접미사(접두사) 등이 어휘생성과 어휘신장의 관점에서 교수법의 적용가능성이 논의되었다. 결론부에서는 외국어를 습득하고자하는 학습자에게 일방적이고 획일적인 암기식 위주의 어휘학습방법에서 벗어나, 목표어가 요구하는 새로운 어휘를 획득하는데 비교적 용이하며 또한 체계적으로 습득 할 수 있도록 인지론에 기대어 텍스트, 문장, 어휘영역 등이 투입되어 적용되었으며, 이에 상응되게 구체적인 몇몇 방안들이 제시되었다. 학습자들이 텍스트를 읽고 중심내용을 찾아내며, 단락을 구획하고 또한 체계를 파악하는데 있어서 어휘연습은 외국어 교수법 측면에서도 매우 관여적이며 시의적절한 과제라 생각된다.

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Polyuria after Surgery of Ruptured Cerebral Aneurysm : with Special Reference to the Administration of Osmotic Diuretics

  • Kang, Sung-Don;Kim, Jong-Moon
    • Journal of Korean Neurosurgical Society
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    • v.38 no.6
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    • pp.431-434
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    • 2005
  • Objective : Subarachnoid hemorrhage[SAH] is commonly associated with polyuria [solute diuresis or water diuresis]. The authors investigate the incidence and clinical characteristics of polyuria with special reference to the administration of osmotic diuretics. Methods : One hundred and forty eight patients with high urine output [>200ml/hr] after ruptured cerebral aneurysm operated early from Jan 1998 to Jun 2003 were selected. Water diuresis [diabetes insipidus, DI] was differentiated from solute diuresis by lower urine specific gravity [<1.005] and higher plasma osmolality. The incidence and mode of onset of polyuria were compared between two types of diuresis. Additionally, the relationships between development of polyuria and clinical features including aneurysm location, clinical grade, Fisher grade, and outcome were analyzed. Osmotic diuretics were not routinely used in patients with Hunt-Hess grade I-III since July 2001. Results : Annual incidence of polyuria decreased markedly since July 2001 : 45.2% in 1998, 34.5% in 2001, 11.9% in 2003. Postoperative DI occurred in $2.4{\sim}11.1%$. DI developed mainly from ruptured anterior communicating artery aneurysm. The mean interval between the last SAH and the onset of DI was 7.1 days [range $1{\sim}27$ days] and lasted mean 4.6 days. When compared with solute diuresis, the development of DI was significantly delayed. Other clinical features were not closely related to polyuria. Conclusion : Uncontrolled polyuria may lead to cerebral ischemia and electrolyte imbalance because SAH patients are already predisposed to hypovolemia, and will risk precipitating the opposite situation with overhydration. We can decrease the development of polyuria without routine use of osmotic diuretics, by avoiding the increased intracranial pressure such as the intraoperative ventriculostomy and gentle brain retraction in good grade patients.

Intracranial Aneurysms in the 3rd and 4th Decades in Comparison with Those in the 8th and 9th Decades

  • Kim, Chang-Hyun;Park, Seong-Hyun;Park, Jae-Chan;Hwang, Jeong-Hyun;Sung, Joo-Kyung;Hamm, In-Suk
    • Journal of Korean Neurosurgical Society
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    • v.38 no.1
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    • pp.28-34
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    • 2005
  • Objective : This study is performed to compare older with younger groups about clinical characteristics and overall outcome of treatments for the intracranial aneurysms. Methods : We retrospectively investigated 633 patients with cerebral aneurysms who were admitted to our institute from January 2000 to May 2004. The authors divided the patients of cerebral aneurysm into two groups, one the third, fourth decades and the other eighth, ninth decades, analyzed clinical characteristics and overall outcome of treatments. Results : There were 57 patients [9.0%] under 39years old and 58 patients [9.2%] over 70. The female to male sex ratio was 0.5 : 1 in the younger group[YG] and 7.3 : 1 in the older group[OG], showing a female predominance with increasing age. In the YG, aneurysms were found in anterior communicating artery[A-com] [44.8%], middle cerebral artery [31.0%]. In the OG, aneurysm of posterior communicating artery [30.1%] was most common followed by that of A-com [26.9%]. More smokers and alcoholics were found in the YG. Older age was related to poor Hunt-Hess grade, Fisher's grade on admission, high incidence of unruptured aneurysms, and endovascular surgery. There was a higher prevalence of hypertension, intraventricular hematoma, hydrocephalus, and rebleeding in the preoperative state in the OG and postoperative complications including hydrocephalus, subdural fluid collection, and systemic complications. Overall outcome was poorer with advancing age [p=0.01]. Conclusion : The patients with aneurysms in the YG have distinct characteristics compared to those in the OG. Because of a good clinical grade on admission, a thin subarachnoid clot, and Low incidence of perioperative complications, the overall outcomes of the young patients were better than those of the old patients.

Impact of Cardio-Pulmonary and Intraoperative Factors on Occurrence of Cerebral Infarction After Early Surgical Repair of the Ruptured Cerebral Aneurysms

  • Chong, Jong-Yun;Kim, Dong-Won;Jwa, Cheol-Su;Yi, Hyeong-Joong;Ko, Yong;Kim, Kwang-Myung
    • Journal of Korean Neurosurgical Society
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    • v.43 no.2
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    • pp.90-96
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    • 2008
  • Objective: Delayed ischemic deficit or cerebral infarction is the leading cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (SAH). The purpose of this study is to reassess the prognostic impact of intraoperative elements, including factors related to surgery and anesthesia, on the development of cerebral infarction in patients with ruptured cerebral aneurysms. Methods: Variables related to surgery and anesthesia as well as predetermined factors were all evaluated via a retrospective study on 398 consecutive patients who underwent early microsurgery for ruptured cerebral aneurysms in the last 7 years. Patients were dichotomized as following; good clinical grade (Hunt-Hess grade I to III) and poor clinical grade (IV and V). The end-point events were cerebral infarctions and the clinical outcomes were measured at postoperative 6 months. Results: The occurrence of cerebral infarction was eminent when there was an intraoperative rupture, prolonged temporary clipping and retraction time, intraoperative hypotension, or decreased $O_2$ saturation, but there was no statistical significance between the two different clinical groups. Besides the Fisher Grade, multiple logistic regression analyses showed that temporary clipping time, hypotension, and low $O_2$ saturation had odds ratios of 1.574, 3.016, and 1.528, respectively. Cerebral infarction and outcome had a meaningful correlation (${\gamma}$=0.147, p=0.038). Conclusion: This study results indicate that early surgery for poor grade SAH patients carries a significant risk of ongoing ischemic complication due to the brain's vulnerability or accompanying cardio-pulmonary dysfunction. Thus, these patients should be approached very cautiously to overcome any anticipated intraoperative threat by concerted efforts with neuro-anesthesiologist in point to point manner.

All-ceramic versus titanium-based implant supported restorations: Preliminary 12-months results from a randomized controlled trial

  • Weigl, Paul;Trimpou, Georgia;Grizas, Eleftherios;Hess, Pablo;Nentwig, Georg-Hubertus;Lauer, Hans-Christoph;Lorenz, Jonas
    • The Journal of Advanced Prosthodontics
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    • v.11 no.1
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    • pp.48-54
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    • 2019
  • PURPOSE. The aim of the present randomized controlled study was to compare prefabricated all-ceramic, anatomically shaped healing abutments followed by all-ceramic abutments and all-ceramic crowns and prefabricated standard-shaped (round-diameter) titanium healing abutments followed by final titanium abutments restored with porcelain-fused-to-metal (PFM) implant crowns in the premolar and molar regions. MATERIALS AND METHODS. Forty-two patients received single implants restored either by all-ceramic restorations (test group, healing abutment, final abutment, and crown all made of zirconia) or conventional titanium-based restorations. Immediately after prosthetic incorporation and after 12 months of loading, implant survival, technical complications, bone loss, sulcus fluid flow rate (SFFR) as well as plaque index (PI) and implant stability (Periotest) were analyzed clinically and radiologically. RESULTS. After 12 months of loading, an implant and prosthetic survival rate of 100% was observed. Minor prosthetic complications such as chipping of ceramic veneering occurred in both groups. No statistical significant differences were observed between both groups with only a minimum of bone loss, SFFR, and PI. CONCLUSION. All-ceramic implant prostheses including a prefabricated anatomically shaped healing abutment achieved comparable results to titanium-based restorations in the posterior region. However, observational results indicate a benefit as shaping the peri-implant soft-tissue with successive provisional devices and subsequent compression of the soft tissue can be avoided.

A Structural Model for Chemotherapy Related Cognitive Impairment and Quality of Life in Breast Cancer Patients (유방암 환자의 항암화학요법 관련 인지기능 변화와 삶의 질의 구조모형)

  • Lee, Jung Ran;Oh, Pok Ja
    • Journal of Korean Academy of Nursing
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    • v.49 no.4
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    • pp.375-385
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    • 2019
  • Purpose: This study aimed to develop and test a structural model for chemotherapy-related cognitive impairment of breast cancer patients based on a literature review and Hess and Insel's chemotherapy-related cognitive change model. Methods: The Participants consisted of 250 patients who were ${\geq}19$ years of age. The assessment tools included the Menopause Rating Scale, Symptom Experience Scale, Hospital Anxiety and Depression Scale, Everyday Cognition, and Functional Assessment of Cancer Therapy-Breast Cancer. Data were analyzed using the SPSS 21.0 and AMOS 21.0 programs. Results: The modified model was a good fit for the data. The model fit indices were ${\chi}^2=423.18$ (p<.001), ${\chi}^2/df=3.38$, CFI=.91, NFI=.91, TLI=.89, SRMR=.05, RMSEA=.09, and AIC=515.18. Chemotherapy-related cognitive impairment was directly influenced by menopausal symptoms (${\beta}=.38$, p=.002), depression and anxiety (${\beta}=.25$, p=.002), and symptom experiences (${\beta}=.19$, p=.012). These predictors explained 47.7% of the variance in chemotherapy-related cognitive impairment. Depression and anxiety mediated the relations among menopausal symptoms, symptom experiences, and with chemotherapy related cognitive impairment. Depression and anxiety (${\beta}=-.51$, p=.001), symptom experiences (${\beta}=-.27$, p=.001), menopausal symptoms (${\beta}=-.22$, p=.008), and chemotherapy-related cognitive impairment (${\beta}=-.15$, p=.024) had direct effects on the quality of life and these variables explained 91.3%. Conclusion: These results suggest that chemotherapy-related toxicity is highly associated with cognitive decline and quality of life in women with breast cancer. Depression and anxiety increased vulnerability to cognitive impairment after chemotherapy. Nursing intervention is needed to relieve chemotherapy-related toxicity and psychological factor as well as cognitive decline for quality of life in patients undergoing chemotherapy.