• The Korean Journal of Pain
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• v.18 no.2
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• pp.232-234
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• 2005

Stellate ganglion block (SGB) is one of the most widely used treatment modalities for a broad range of disorders, including otolaryngologic indications such as Meniere's disease and sudden hearing loss. We present a case of a vertiginous attack following SGB for the management of Meniere's disease. A 31-year-old female, suffering from Meniere's disease, underwent repeated right side SGBs with 6 ml of 1% mepivacaine after negative aspiration tests for blood. The eleventh block was performed in the usual manner. Several seconds after injection, she showed agitation, anxiety, nystagmus, and left-sided tinnitus. Two minutes later, her tinnitus and nystagmus were resolved. Fifteen minutes after injection, she experienced acute onset of severe vertigo, nausea, and vomiting. However, her symptoms were gradually alleviated within two hours.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.14 no.2
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• pp.194-197
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• 2001

Progressive pigmented purpuric dermatosis(Schamberg's disease, purpura simplex) is an uncommon eruption characterized by petechiae and patches of brownish pigmentation, particularly on the lower extremities. Lesions remain for months or years and present only a cosmetic problem. there is no hematologic disease, venous insufficiency, or associated internal disease. The most characteristic feature is orange brown, pinhead-sized "cayenne pepper" spots. It is hard to find similar disease in Oriental Medicine, however it could be though related with 瘀血. We observed and treated a 25 old female with progressive pigmented purpuric dermatosis on her lower extremities, without pain and itching sign. About 1 year after our treatment, herb-medication. acupuncture treatment, negative therapy and applied aroma oil in order to remove the 瘀血(a kind of congestion) & inner heat and promote the circulation of her blood, the area of pigmented purpuric dermatosis was decreased remarkably and the colour was lighter. She is been treated continuously now and satisfied with the efficacy of treatment.

• Human Ecology Research
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• v.62 no.2
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• pp.337-349
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• 2024

The aim of this study was to explore the mediating effects of adult attachment and marital satisfaction on the relationship between childhood maternal attachment and parenting behavior. A total of 372 mothers of preschoolers completed questionnaires on childhood maternal attachment, adult attachment, marital satisfaction, and parenting behavior. Adult attachment was analyzed by distinguishing between attachment anxiety and attachment avoidance. Parenting behavior was categorized into positive and negative behaviors. For the main analyses, Preacher and Hayes's PROCESS macro program was used to examine serial mediating effects. The results revealed that attachment anxiety mediated the effects of mothers' childhood attachment experiences on both positive and negative parenting behavior. However, attachment avoidance only mediated the effects on positive parenting behavior. Marital satisfaction mediated the effects of mothers' childhood attachment experiences on both positive and negative parenting behavior. Notably, the sequential mediating effects of attachment anxiety and marital satisfaction were not significant for either positive or negative parenting behavior. By contrast, the sequential mediating effects of attachment avoidance and marital satisfaction were significant for both positive and negative parenting behavior. These findings elucidate the predictive factors for parenting behavior within a process model framework, providing valuable insights for parental education and counseling aimed at enhancing mothers' parenting practices.

• Journal of Interdisciplinary Genomics
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• v.1 no.2
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• pp.19-22
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• 2019

CATCH 22 syndrome is rare genetic disease that has various manifestations. Cervical vertebral anomaly, such as Klippel-Feil anomaly, is frequently observed in the patients with CATCH22 syndrome. We present the case of an 11-year-old female patient with CATCH22 syndrome and Klippel-Feil anomaly who had been treated torticollis using the customized soft neck collar. During the patient's first visit to our clinic, she presented with low ear set, skull deformity, intellectual disability, and tilting of the head to the left by approximately 25 degrees. Imaging studies revealed multisegmental fusion and C3 hemivertebrae of the cervical spine and left thoracic scoliosis at T4 with 50 degrees of Cobb's angle. We instructed passive stretching and applied the customized soft neck collar we invented. The ipsilateral aspect of the neck collar is designed to provide vertical support between the clavicle and mandibular angle and is adjustable in height. The Velcro was attached to the neck collar at the point of contact with the ipsilesional mandibular angle, which provides negative sensory feedback, inducing her to tilt neck to the contralesional side. We applied the neck collar for 2 hours a day. After 1 year of treatment, her neck inclination angle improved from 25 to 10 degrees. Providing negative sensory feedback using the customized soft neck collar can be one of the treatment options of postural management in patients with torticollis in cases of CATCH 22 syndrome combined with Klippel-Feil anomaly.

• Journal of the Korean Home Economics Association
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• v.49 no.7
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• pp.123-133
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• 2011

The purpose of this study was to investigate the effect of relationship variables between mother-in-law and son-inlaw on a son-in-law's relation-satisfaction and negative perception. The son-in-law subjects were 319 married men aged 20-70 years, who were living their mother-in-laws in Daegu, Kyungpook, the Seoul National Capital Area(Seoul, Kyeonggy, Incheon), Busan or Kyungnam. The major findings of this study are as follows: (1) there was a significant difference in a son-in-law's relation-satisfaction of his relationship with his mother-in-law according to the number of children and (2) mutual support and a mother-in-law's conflicting attitude toward her son-in-law affected the son-in-law's relation-satisfaction and negative perception of his relationship with his mother-in-law.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7651-7656
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• 2013

Background: Breast cancer is the most common malignancy among women in both developed and developing countries. The burden is increasing in low-income and middle-income countries (LMCs) and threatens the public health of such societies. Introduction of expensive monoclonal antibodies to cancer treatment regimens poses a real challenge in the health systems of LMCs. Despite controversy of cost-effectiveness of bevacizumab in breast cancer, some studies indicate gain of patients from this drug. The present study aimed to propose a priority setting model for administration of anti-angiogenic agents in breast cancer via assessment of tumor angiogenesis by the microvessel density (MVD) method and associations with clinicopathological characteristics (including simultaneous mutations of TP53 and HER-2 genes). Materials and Methods: Age, axillary lymph nodes status, tumor size, stage and grade, estrogen and progesterone receptors status, HER-2/neu status (by immunohistochemistry and FISH test), TP53 mutation, Ki-67 (for proliferation assay) and CD34 (for angiogenesis assay) were assessed in 111 breast cancer patients. The molecular subtype of each tumor was also determined and correlations of simultaneous mutations of HER-2 and p53 genes with angiogenesis and other clinicopathological characteristics were evaluated. Results: There were significant associations between simultaneous mutations of HER-2 and p53 genes and all other parameters except tumor size. The degree of angiogenesis in the ERBB2 subtype was greater than the others. Younger patients showed a higher angiogenesis rate rather those older than 50 years. Conclusions: Our results demonstrated that patients with simultaneous mutations of HER-2 and p53 genes, those with ERBB2 molecular subtype and also younger women (often triple negative) seem more eligible for obtaining anti-angiogenic agents. These results suggest a model for priority setting of patients with breast cancer for treatment with anti-angiogenic drugs in LMCs.

• Sim-seong Yeon-gu
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• v.25 no.2
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• pp.123-162
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• 2010

The author tried to analyse a Korean fairy tale "the traveller and the fox". The essence of the story is as follows; A traveller who was wandering in mountains found a house with a light. There was a beautiful woman who was very kind to give food and shelter. But she was a fox that tried to kill him with a knife. He asked her to bring a basket of water and he broke the wall with it to run away. The fox chased and he fell down a cliff to ride on the back of a tiger. The tiger ran into a cave and give him to her babies as a prey. He killed them by throwing stones and climbed a tree out of the cave. There came foxes and the tiger and they killed each other. He came back to the village with the fur of the foxes and the tiger. The author tried to understand the contents of the story symbolically and interpret them from the perspective of analytical psychology. On conclusion, the traveller was on the individuation process and experienced the negative anima (the fox) and the negative mother archetype (the tiger) and its negative subsidiaries (the tiger's babies). He tried to be consciously alert and paid continuous attention so that he could get out of the status and get new insight. During this process, it was meaningful that he could actively get an appropriate aid of positive mother archetype and Self symbolized by the water and the tree respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1261-1264
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• 2016

Background: In breast cancer (BC), it has been suggested that nuclear overexpression of p53 protein might be an indicator of poor prognosis. The aim of the current study was to evaluate the expression of p53 BC in Kurdish women from the West of Iran and its correlation with other clinicopathology figures. Materials and Methods: In the present retrospective study, 231 patients were investigated for estrogen receptor (ER) and progesterone receptor (PR) positivity, defined as ${\geq}10%$ positive tumor cells with nuclear staining. A binary logistic regression model was selected using Akaike Information Criteria (AIC) in stepwise selection for determination of important factors. Results: ER, PR, the human epidermal growth factor receptor 2 (HER2) and p53 were positive in 58.4%, 55.4%, 59.7% and 45% of cases, respectively. Ki67 index was divided into two groups: 54.5% had Ki67<20% and 45.5% had Ki67 ${\geq}20%$. Of 214 patients, 137(64%) had lymph node metastasis and of 186 patients, 122(65.6%) had vascular invasion. Binary logistic regression analysis showed that there was inverse significant correlation between lymph node metastasis (P=0.008, OR 0.120 and 95%CI 0.025-0.574), ER status (P=0.006, OR 0.080, 95%CI 0.014-0.477) and a direct correlation between HER2 (P=005, OR 3.047, 95%CI 1.407-6.599) with the expression of p53. Conclusions: As in a number of studies, expression of p53 had a inverse correlation with lymph node metastasis and ER status and also a direct correlation with HER2 status. Also, p53-positivity is more likely in triple negative BC compared to other subtypes.

• Journal of the Korean Home Economics Association
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• v.44 no.3 s.217
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• pp.51-59
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• 2006

The purpose of this study is to determine the relevant variables of parent-leadership that influence family strength based on the transformational leadership and transactional leadership proposed by Bernard M. Bass and to investigate the primary impact of leadership on the subordinate's job satisfaction and job involvement to his/her supervisor. Therefore, this study will provide implications for the family through a diagnosis of the effect by leadership. The results of this research are as follows : 1) How is the relationship of parent-leadership and family strength? A positive correlation was found between transformational leadership scores and family strength. A negative correlation was found between nontransactional leadership scores and family strength. 2) How had transformational leadership and transactional leadership affected on the family strength? Transformational leadership had the strongest effect on family strength. How had the 7 sub- factors of transformational/transactional leadership affected family strength? Idealized influence and contingent reward had strong effect on family strength but management by except had a negative effect on family strength.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8397-8403
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• 2016

Background: Breast cancer (BCa) is the most common malignancy in Mexican women. A set of histopathological markers has been established to guide BCa diagnosis, prognosis and treatment. Nevertheless, in only a few Mexican health services, such as that of the Secretariat of National Defense (SEDENA for its acronym in Spanish), are these markers commonly employed for assessing BCa. The aim of this study was to explore the association of Ki67, TP53, HER2/neu, estrogenic receptors (ERs) and progesterone receptors (PRs) with BCa risk factors. Materials and Methods: Clinical histories provided background patient information. Immunohistochemical (IHC) analysis was conducted on 48 tissue samples from women diagnosed with BCa and treated with radical mastectomy. The Chi square test or Fisher exact test together with the Pearson and Spearman correlation were applied. Results: On average, patients were $58{\pm}10.4$ years old. It was most common to find invasive ductal carcinoma (95.8%), histological grade 3 (45.8%), with a poor Nottingham Prognostic Index (NPI; 80.4%). ERs and PRs were associated with smoking and alcohol consumption, metastasis at diagnosis and Ki67 expression (p<0.05). PR+ was also related to urea and ER+ (p<0.05). Ki67 was associated with TP53 and elevated triglycerides (p<0.05), and HER2/neu with ER+, the number of pregnancies and tumor size (p<0.05). TP53 was also associated with a poor NPI (p<0.05) and CD34 with smoking (p<0.05). The triple negative status (ER-/PR-/HER2/neu-) was related to smoking, alcohol consumption, exposure to biomass, number of pregnancies, metastasis and a poor NPI (p<0.05). Moreover, the luminal B subty was associated with histological type (p=0.007), tumor size (p=0.03) and high cholesterol (p=0.02). Conclusions: Ki67, TP53, HER2/neu, ER and PR proved to be related to several clinical and pathological factors. Hence, it is crucial to determine this IHC profile in women at risk for BCa. Certain associations require further study to understand physiological/biochemical/molecular processes.