• Journal of English Language & Literature
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• v.56 no.2
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• pp.219-236
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• 2010

As a poet, a reviewer of books, and an editor of a major literary journal, Marianne Moore participated in aesthetic revolution which invented the American poetry of the twentieth century. Of all the modernists, she was one of the few truly technical originals, and became an endearing mascot of poetry. Innately attentive to detail, Moore wrote a myriad of poems about animal and plant subjects, and set out to develope and secure her own particular paradigm for modernist poetic and the poetry of objective and scientific description. Foregrounding a mind scientifically trained, Moore used her verse to demonstrate a means by which to see the reality beyond the obvious. Ironically enough, however, a central difficulty with understanding Moore's poetry lies with her concern for such scientific or surface description and precision. In order to understand Moore's poetry fully, it is of special necessity to appreciate relativity among the seemingly disparate entities such as science and literature, as Moore herself did. This paper explores the way in which the poetic techniques of Moore substantiate her sense of morality that underlies the creation of her poetry. Rather than merely addressing her artistic genius or craftsmanship as a modernist poet, Moore's methods engage the power of imagination, magic, lifting the human spirit and eschewing anthropocentric perspectives. For Moore, the poet's magic comes by diligence. In so doing, as I would argue here, Moore draws on the nature of language, especially what Bakhtin insisted with his notions of polyphony and carnival. By introducing openness to various perspectives and meanings in her verse, Moore succeeds in maintaining her own sense of creativity while continuing to acknowledge morality. In a similar skein, her use of active verbs in animal poems and the kaleidoscopic descriptions demonstrate how Moore accommodates imagination and reality, and form and content.

• Clinical and Experimental Pediatrics
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• v.45 no.7
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• pp.917-922
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• 2002

An unbalanced translocation is frequently the result of inheritance of an unbalanced haploid set from a parent with a balanced translocation. Families in which one parent is a balanced translocation carrier fall into the following classes : Those in which none of the possible abnormal offsprings is viable; Those in which one type of offspring, usually the one with the smaller deletion, is born alive; Those in which two types of abnormal offspring are viable. We report a neonate whose karyotype was 46,XX,der(2)t(2;7)(q21;p21.2),der(20)t(2;20)(q21;p13). She was small for her gestational age and had multiple anomalies such as exophthalmos, corneal opacity, short neck, tongue tie, clinodactyly, atrial septal defect, patent ductus arteriosus and ventriculomegaly. Moreover, her mother's karyotype was 46,XX,der(2)t(2;7)(q21;p21.2),del(16)(q22.1),der(20)t(2;20)(q21;p13) but her father had normal karyotype. The same derivative chrosomes were found between mother and her infant, except for del(16)(q22.1) in her mother and these same unbalanced translocations in a two-generation family are extremely rare.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5551-5556
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• 2014

Background: The prognostic value of human epidermal growth factor receptor-2 (HER-2/neu) for survival of patients with colorectal cancer (CRC) is still ambiguous. We therefore performed a meta-analysis to evaluate its prognostic significance. Materials and Methods: We searched the MEDLINE and EMBASE databases for published literature investigating associations between HER-2/neu status and overall survival of patients with CRC. A meta-analysis was performed using a DerSimonian-Laird model and publication bias was investigated by Begg's and Egger's tests. Subgroup analysis was also conducted according to the study design type, study quality score, cut-off value for HER-2/neu overexpression, publication region, patient number and publication year. Results: A total of 17 eligible studies involving 2,347 patients were identified for this meta-analysis. The combined hazard ratio (HR) was 1.31 (95% confidence interval (CI): 0.96-1.79), suggesting that HER-2/neu overexpression was not significantly associated with overall survival of patients with CRC. However, subgroup analysis revealed that HER-2/neu overexpression had an unfavorable impact on survival when the analysis was restricted to subgroups of study quality score ${\leq}5 $(HR=1.56, 95%CI: 1.17-2.10), Asian patients (HR=1.74, 95%CI: 1.22-2.49), patient number ${\leq}106$ (HR=1.57, 95%CI: 1.01-2.44), publication year before 2003 (HR=1.59, 95%CI: 1.02-2.49), and prospectively designed study (HR=3.62, 95%CI: 1.42-9.24). The effect disappeared in subgroups of study quality scores > 5 (HR=0.69, 95%CI: 0.33-1.44), non Asian patients (HR=1.14, 95%CI: 0.77-1.70), patients' number > 106 (HR=1.07, 95%CI: 0.67-1.72), publication year after 2003 (HR=1.13, 95%CI: 0.76-1.69), and retrospectively designed study (HR=1.22, 95%CI: 0.89-1.67). Conclusions: Our meta-analysis suggests that HER-2/neu overexpression might not be a significantly prognostic indicator for patients with CRC. Further studies are required to confirm these results.

• International Journal of Advanced Culture Technology
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• v.7 no.2
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• pp.227-237
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• 2019

In this paper, we have developed a Retina Healthcare Service System through which the patient himself/herself can manage his/her retina health. In the case of conventional portable ophthalmic cameras, patients cannot check their eye health on their own because most of them are used by doctor in environments where ophthalmography cannot be performed properly. This system consists of web, app and camera modules, and when a patient mounts a camera module for fundus photography on his / her smart phone and then photographs his / her fundus through the app, the image is transmitted to a server, and the transmitted image reads the fundus the patient's fundus image status in the fundus image reading model learned using deep learning. When the doctor expresses his/her opinions about the patient 's eye condition based on the reading result and the fundus photograph, the patient can check through the app and judge whether to receive ophthalmologic treatment.

• Transactions of Materials Processing
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• v.30 no.2
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• pp.74-82
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• 2021

Stretch-flangeability, which is the ability of sheet steels to be deformed into complex shapes, is a critical formability property in automobile body parts. In this study, the center-hole for hole expansion test, which is normally used to evaluate the stretch-flangeability of sheet steels, was prepared by both punching and electrical discharge machining (EDM) methods. Hole expansion ratio (HER) of punched hole was far lower than the HER of EDM drilled hole because of damage/crack in hole-edge due to punching process. The effect of hole-edge condition on HER was quantified by mechanical, fractographic and geometric factors. Based on these factors, the empirical equation used to determine HER for various sheet steels was derived using non-linear regression.

• Educational Technology International
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• v.8 no.2
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• pp.93-112
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• 2007

This case study explored the potential for implementing content-based English as a Foreign Language (EFL) instruction in a Korean middle school facilitated by computer-mediated communication (CMC). The instructor scaffolded the student participant's language learning online, helping her to produce English output on her own. While experimental social studies lessons on the topic of stereotyping were taught, data were collected on the student's online exchanges with her counterpart in Iran about their respective cultures. Findings show that the student from Korea was able to better understand her own culture as a result of the online experience. This interaction and the in-class lessons have demonstrated that content-based EFL instruction is a viable alternative to the school's existing curriculum.

• Journal of Gastric Cancer
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• v.24 no.1
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• pp.29-56
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• 2024

In recent years, remarkable progress has been made in the molecular profiling of gastric cancer. This progress has led to the development of various molecular classifications to uncover subtype-specific dependencies that can be targeted for therapeutic interventions. Human epidermal growth factor receptor 2 (HER2) is a crucial biomarker for advanced gastric cancer. The recent promising results of novel approaches, including combination therapies or newer potent agents such as antibody-drug conjugates, have once again brought attention to anti-HER2 targeted treatments. In HER2-negative diseases, the combination of cytotoxic chemotherapy and programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) inhibitors has become the established standard of care in first-line settings. In the context of gastric cancer, potential biomarkers such as PD-L1 expression, Epstein-Barr virus, microsatellite instability, and tumor mutational burden are being considered for immunotherapy. Recently, promising results have been reported in studies on anti-Claudin18.2 and fibroblast growth factor receptor 2 treatments. Currently, many ongoing trials are aimed at identifying potential targets using novel approaches. Further investigations will be conducted to enhance the progress of these therapies, addressing challenges such as primary and acquired resistance, tumor heterogeneity, and clonal evolution. We believe that these efforts will improve patient prognoses. Herein, we discuss the current evidence of potential targets for systemic treatment, clinical considerations, and future perspectives.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.6 no.2
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• pp.185-197
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• 1999

For the past 10 years, the number of male smokers has dwindled. On the other hand, the number of female smokers has increased abruptly. Cigarette smoking is more hazardous to a woman than to a man because it can affect her health and her fetus during pregnancy. Many studies show that cigarette smoking is one of the most important risk factors determining the mortality and the morbidity of various kinds of diseases such as lung cancer and pharyngeal cancer. But, it is also known to be one of the risk factors we can handle and prevent easily. The subjects of this study consisted of 263 female nursing students in Seoul and Chonbuk Province. Using questionnaires, we were collected data from December 1 to December 10 1998. The questionnaire included 24 questions related to environmental factors and 14 questions related with self-efficacy. The statistical analysis was done with SPSS ver. 8.0(SPSS Inc. U.S.). The results of this study are as follows. 1) Cigarette smoking in women was influenced by her family or friends. That is to say, the higher number of her friends or family members who smoked cigarettes, the more likely a woman was to become a smoker. Economic status and knowledge level about the risks of cigarette smoking were also related to women smoking. So, women with lower levels of economic status and less knowledge about the risks of cigarette smoking were the more likely to become smokers. 2) Woman with higher levels of self-efficacy were less likely to become smokers. 3) The factors influencing a woman's smoking were whether her friends smoked, whether her mother smoked and her self-efficacy in that order. Environmental factors, self-efficacy were found to be important factors influencing smoking in women. It is suggested a quit-smoking program for women college students, be based on consideration of these environmental factors and self-efficacy.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.25 no.3
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• pp.133-133
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• 1989

The maneuverabilities of the M.S. Pusan 404 are studied, based on maneuvering indices and the data obtained from her Z test. The results obtained are summarized as follows: 1. The maneuvering indices K' and T' of the M.S Pusan 404 are 0.9359, 0.1955 at 10° Z test and 0.9781, 0.5802 at 20° Z test and 0.9108, 0.7090 at 30° Z test respectively. The above calculated values K', T' showed that her maneuverabilities are more effective when the rudder is used to small angle than to large angle. 2. As her maneuvering indices K' and T' at 10° Z test are smaller than the standard maneuvering indices of fishing boats, her turning ability was found to be lower but her obeying ability higher. 3. the running distance of a turn at her 10° Z test was about 8.7 times her own len호 and she was considered to have good maneuverabilities synthetically.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.25 no.3
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• pp.125-128
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• 1989

The maneuverabilities of the M.S. Pusan 404 are studied, based on maneuvering indices and the data obtained from her Z test. The results obtained are summarized as follows: 1. The maneuvering indices K' and T' of the M.S Pusan 404 are 0.9359, 0.1955 at 10$^{\circ}$ Z test and 0.9781, 0.5802 at 20$^{\circ}$ Z test and 0.9108, 0.7090 at 30$^{\circ}$ Z test respectively. The above calculated values K', T' showed that her maneuverabilities are more effective when the rudder is used to small angle than to large angle. 2. As her maneuvering indices K' and T' at 10$^{\circ}$ Z test are smaller than the standard maneuvering indices of fishing boats, her turning ability was found to be lower but her obeying ability higher. 3. the running distance of a turn at her 10$^{\circ}$ Z test was about 8.7 times her own len호 and she was considered to have good maneuverabilities synthetically.