• Journal of the Korean Society for Precision Engineering
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• v.21 no.8
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• pp.97-105
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• 2004

The vertical roller mill is the important machine grinding and mixing various crude materials in the manufacturing process of portland cement. Table liner is one of grinding elements of vertical roller mill and is subjected to the cyclic bending stress by rollers and the centrifugal force by rotation of table. It demands $4{\times}10^7$ expense of life but has $4{\times}10^6~-8{\times}10^6$ cycle. It fractures at the edge of grinding path of outside roller The repair expense fur it amounts to 30% of total maintenance of vertical roller mill. Therefore, this study shows the fracture mechanism of table liner of vertical roller mill using HDM and fatigue analysis

• Proceedings of the KWS Conference
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• 2002.10a
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• pp.657-660
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• 2002

In this paper, a study on the residual stress of plate with longitudinal stiffeners is explained in terms of the welding sequences. In order to verify the results of numerical analysis, the hole drilling method (HDM) is performed, to measuring the residual stresses of the test plates in $CO_2$ Flux Cored Arc Welding (FCAW) under various welding conditions. The non-linear transient analysis technique for the numerical analysis in a large and complicate structure is considered. The residual stress of plate in consideration of the welding sequences and directions is evaluated by some numerical simulations and also by experiments. Comparison of numerical analysis results with experimental data shows the accuracy and validity of the proposed method.

• Journal of Welding and Joining
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• v.8 no.4
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• pp.76-82
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• 1990

Lots of research works have been done to improve the accuracy of the hole drilling method to measure residual stress by many investigators. In this study, first, size effect of specimen was analyzed based on the solution of hole in a strip under tension. If the ratio of hole diameter tothe strip width is less than 0.2, the stress distribution around hold may be given from the solution of hole in an infinite plate. Second, the residual stress above $0.6{\sigma}_y$(yield stress) may be measured less than the actual stress by 10-15 percent. Third, eccentricity of hole relative to the rosette center effects on the accuracy of residual stress measurements by 10 percent. The error due to eccentricity of hole can be corrected by the iteration method or the direct method.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.163-169
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• 2003

The vertical roller mill is the important machine grinding and mixing various crude materials in the manufacturing process of portland cement. Table liner is one of grinding elements of vertical roller mill and is subjected to the cyclic bending stress by rollers load and the centrifugal force by rotation of table. It demands $4{\times}10^7$ cycle but has $4{\times}10^6{\sim}8{\times}10^6$ cycle. It fractures at the edge of grinding path of outside roller. The repair expense for it amounts to 30% of total maintenance of vertical roller mill. Therefore, this study shows the fracture mechanism of table liner for vertical roller mill using HDM and fatigue analysis

• BMB Reports
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• v.42 no.5
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• pp.299-303
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• 2009

In this study, we use promoter analysis to show that interaction between Jab1 and p53 induces suppression of p53 activation in U2OS and H1299 cells. Interaction between p53 and Jab1 was further confirmed by immunoprecipitation and immunofluorescent analyses. In particular, Jab1 was able to induce nuclear export of p53 as previously reported. When Jab1 was overexpressed in U2OS cells followed by etoposide or hydrogen peroxide ($H_2O_2$), cell death induced by such stresses was protected against. On the contrary, when the level of Jab1 was suppressed in U2OS cells, cytotoxicity imposed by etoposide and $H_2O_2$ was dramatically increased, suggesting a cell protective role for Jab1. These results indicate that Jab1 is a negative regulator of p53 and a plausible oncogene.

• Journal of Welding and Joining
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• v.31 no.2
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• pp.43-48
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• 2013

This paper Investigated the characteristics of residual stress in weld is composed of typical specimens, are investigated by using three dimensional thermal elasto-plastic FEM analysis. Numerically calculated residual stresses in the gas welds were then compared with experimental results obtained by the hole-drilling method. Using the stress amplitude (${\sigma}a$)R at the hot spot point of gas weld, the relations obtained as the fatigue test results for typical specimens having various dimensions and shapes were systematically rearranged to obtain the (${\sigma}a$)R-Nf relationship. It was found that more systematic and accurate evaluation of the fatigue strength of plug- and ring-type gas-welded joints can be achieved by using (${\sigma}a$)R.

• International Journal of Korean Welding Society
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• v.4 no.1
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• pp.10-14
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• 2004

In this paper, a study on the residual stress of plate with longitudinal stiffeners is explained in terms of the welding sequences. In order to verify the results of numerical analysis, the hole drilling method (HDM) is performed, to measuring the residual stresses of the test plates in $CO_2$ Flux Cored Arc Welding (FCAW) under various welding conditions. The non-linear transient analysis technique for the numerical analysis in a large and complicate structure is considered. The residual stress of plate in consideration of the welding sequences and directions is evaluated by some numerical simulations and also by experiments. Comparison of numerical analysis results with experimental data shows the accuracy and validity of the proposed method.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.3
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• pp.188-195
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• 2016

Neutrophils and lymphocytes are essential inflammatory cells in the pathogenesis of allergy. In this study, we evaluated the role of house dust mite (HDM) in the interaction between allergic lymphocytes and neutrophils. The extract of Dermatophagoides pteronissinus (DP) showed a stronger anti-apoptotic impact on neutrophil apoptosis in the coculture of allergic neutrophils with allergic lymphocytes when compared with that in allergic neutrophils alone. DP increased IL-6, IL-8, MCP-1, and GM-CSF in allergic lymphocytes, and the increased cytokines were inhibited by rottlerin-an inhibitor of the protein kinase C (PKC) ${\delta}$, as well as by SB202190-a p38 MAPK inhibitor. DP activated p38 MAPK in a time-dependent manner. The activation of p38 MAPK was suppressed by PAR2i, which is a protease-activated receptor (PAR) 2 inhibitor, and rottlerin. Both aprotinin-a serine protease inhibitor-and E64-a cysteine protease inhibitor-were not effective on cytokine secretion of lymphocytes. These results, despite increased cytokines in allergic lymphocytes via DP, did not show any differences between asthma and allergic rhinitis. Molecules, including cytokines, released by DP in lymphocytes inhibited the migration of neutrophils. This finding may further elucidate the pathogenic mechanism of allergic diseases due to HDM.

• Environmental Analysis Health and Toxicology
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• v.30
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• pp.8.1-8.8
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• 2015

Objectives Bedding in childcare centers (CCCs) can hold house dust mite (HDM) allergens. This study examined whether HDM allergen levels can be reduced through the distribution of an educational newsletter on bedding control to parents of CCC children in Korea. Methods All 38 CCCs were measured for Der 1 (sum of Der f 1 and Der p 1) concentrations on classroom floors and bedding before the intervention. Educational newsletters on children's bedding control were sent to 21 CCCs by mail, and teachers were asked to distribute the newsletters to the parents of the children (intervention group). The remaining 17 CCCs were not sent newsletters (control group). The measurement of Der 1 concentrations in 38 CCCs was repeated after the intervention. Dust samples were collected with a vacuum cleaner and analyzed using enzyme-linked immunosorbent assay methods. Results The Der 1 concentrations on the bedding were significantly higher than those on the floors in 38 CCCs at baseline (p < 0.05). Although changes of the Der 1 concentrations for the control group (n=17) were not significant, Der 1 concentrations for the intervention group (n=21) decreased significantly from 2077.9 ng/g dust to 963.5 ng/g dust on the floors and from 3683.9 ng/g dust to 610.4 ng/g dust on bedding (p < 0.05). Conclusions The distribution of educational newsletters on bedding control to parents may be an effective means of controlling HDMs in CCCs.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.817-823
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• 1999

Background: The prevalence of allergic disease has increased substantially over the past decades. The reasons for these trends are complex but include increased environmental allergen exposure. Environmental control measures are of particular importance in the prevention and management of allergic disease. Thus, we purposed to evaluate the changes of causative allergens in allergic patients in Chonbuk provincial area that began industralized recently. Method: To evaluate the allergens epidemiologically, we performed skin prick tests and RAST in 201 allergic patients from February, 1984 to February, 1985 and 339 patients from February, 1997 to February, 1998. Results: The Following results were obtained. 1) Total sensitization rates did not change significantly(74.2% vs 75.8%, p=0.664). 2) Positive reaction rates to pollens were similar(35.8% vs 30.1%, p=0.17). 3) Positive rates to HDM(house dust mite) were decreased(66.1% vs 56.3%, p=0.02). 4) Positive rates to fungi and animal danders were decreased significantly(p<0.001). Conclusion : Environmental allergens associated with hygine in Chonbuk provincial areas such as HDM and fungi are decreased significantly during 13 years.