• Title/Summary/Keyword: HDL

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HDL Codes Generator for Cyclic Redundancy Check Codes (순환중복검사 부호용 하드웨어 HDL 코드 생성기)

  • Kim, Hyeon-kyu;Yoo, Ho-young
    • Journal of IKEEE
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    • v.22 no.4
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    • pp.896-900
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    • 2018
  • Traditionally, Linear Shift Feedback Register (LFSR) has been widely employed to implement Cyclic Redundant Check (CRC) codes for a serial input. Since many applications including network and storage systems demand as high throughput as ever, various efforts have been made to implement CRC hardware to support parallel inputs. Among various parallel schemes, the look-ahead scheme is one of the most widely used schemes due to its short critical path. However, it is very cumbersome to design HDL codes for parallel CRC codes since the look-ahead scheme is inevitable to consider how register and input values move in the next cycles. Thus, this paper proposes a novel CRC hardware generator, which automatically produces HDL codes given a CRC polynomial and parallel factor. The experimental results verify the applicability to use the proposed generator by analyzing the synthesis results from the generated HDL code.

Effects of Plasma Lipoproteins on Expression of Vasular Cell Adhesion Molecule- in Human Microvasuclar Endothelial Cells (혈관내피세포에서 Vascular Cell Adhesion Molecule-1 발현에 대한 혈장 지단백의 효과)

  • 박성희
    • Journal of Nutrition and Health
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    • v.31 no.8
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    • pp.1235-1243
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    • 1998
  • Although an elevated plasma level of high density lipoprotein (HDL) is known as a protective component against the development of atherosclerosis and ensuing coronary heart diseases, the related mechanisms are still not established . It has been clearly demonstrated in the early stages of atherogenesis that adhesion of monocytes and lymphocytes to the vascular endothelium is enhanced via adhesion molecules, and that monocytes and macrophages accumulate in the subendothelial space. The present study has investigated whether isolated plasma HDL plays a role in protection against atherogenesis by inhibiting the expression of vascular cell adhesioin molecule-1(VCAM-1) on the endothelial cells. Effects of plasma native low density lipoprotein (LDL) and ac ethylated LDL(AcLDL) on VCAM-1 expression were also examined by using an immunocytochemical technique. While plasma HDL did not alter the basal expression of VCAM-1 , lipopolysaccharide(LPS) induction of this adhesion modlecule was markedly inhibited at a phyaiological concentration of HDL. In contrast, 30$\mu\textrm{g}$ protein/ml AcLDL increased sifnificantly both basal VCAM-1 expression and its LPD induction , suggesting that this modified LDL enhances leukocyte adhesiion to endothelial cells. Unlike AcLDL , plasma native LDL inhibited significantly VCAM-1 expression. This indicates that LDL did not undergo oxidative modificantion while incubated with endothelial cells. These results suggest that plasam HDL may inhibit atherogenesis by reducing the expression of adhesion molecules, which is a protective mechanism independent of tis reverse cholesterol transport function . Modified LDL is a potent iducer for adhesion molecules in vascular endothelical cells and could play a role in the pathogenesis of atherosclerosis by adhering to blood cells.

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A Study on Nutrient Intakes and Hematological Status of Female College Students of Ulsan City -1. Emphasis on Serum Lipids- (여대생의 영양섭취상태 및 혈액성상에 관한 연구 - 제1보 혈청지질 성분을 중심으로-)

  • 홍순명
    • Journal of Nutrition and Health
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    • v.26 no.3
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    • pp.338-346
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    • 1993
  • The purpose of this study was to examine nutrient intakes, food and daily habits, and serum lipids for female college students. The subjects consisted of 70 female college students aged 20 to 29 years old. Their dietary intakes were assessed by means of 24 hour dietary recall method. Food models and other measuring tools were also used. Concentrations of serum lipids were measured. The energy intake of the subjects averaged 1837Kcal, whereas the expended energy was 1871Kcal. The subjects consumed 310g of carbohydrates, 66g protien, 37g lipid, 14mg iron, 586mg calcium, 513R.E. vitamin A, 1.0mg vitamin B1, 1.3mg vitamin B2 1.5mg niacin, and 69mg vitamin C, respectively. Vitamin A and iron intakes were lower than the RDA. The percentages of total calorie from carbohydrate, fat, and protein were 67%, 18%, 14%, showing desirable calorie construction. The mean serum triglyceride(TG), cholesterol (Chol), HDL-Chol and LDC-Chol concentrations were 72.4mg/dl, 161.3mg/dl, 44.5mg/dl, and 102.3mg/dl, respectively. All of these values seem to fall in the desirable range. There were positive correlations between serum Chol and HDL-Chol or LDL-Chol or TG ; negative correlations between serum Chol and HDL-Chol/LDL-Chol ratio, between serum TG and HDL-Chol or HDL-Chol/LDC-Chol ratio.

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The Effect of Vitamin B6 Deficiency on the Utilization of Fuel and Blood Cholesterol Profile with Regular Exercise-Training in Rats (비타민 B6 부족이 정기적인 운동 훈련시 연료의 이용과 혈액 콜레스테롤 성상에 미치는 영향)

  • 조윤옥
    • Journal of Nutrition and Health
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    • v.29 no.8
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    • pp.881-888
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    • 1996
  • The purpose of this study was to determine whether vitamin B6(B6) deficiency affects fuel utilization and blood cholesterol profile with exercise-training. Twenty-four rats were fed a B6 deficient(-B6) diet or a control (+B6) diet for 5 weeks and either exercised(EX) or nonexercised (NE). EX rats were exercised on treadmill(10$^{\circ}$, 0.5-0.8km/h) for 20 minutes everyday. Glucose(GLU), glycogen (GLY), protein(PRO), trglyceride(TG), free fatty acid(FFA), total cholesterl(TC), HDL-cholesterol(HDL-C) and LDL-choleterol(LDL-C) were compared in plasma(P), liver(L) and skeletal muscle(M) of rats. There was a vitamin effect on the level of P-GLU, P-TG, M-TG, L-GLY, L-PRO and an exercise effect on the level of P-PRO, P-FFA, M-PRO, L-GLY, L-TG, P-TC, P-HDL-C, P-LDL-C. Compared to +B6 rats were lower and there were no differences in P-GLU, P-FFA, P-TG. M-GLY, L-TG, P-TC and P-HDL-C. In EX group, the level of P-TG was higher and M-PRO was lower in -B6 rats. There were no differences in M-GLY, L-TG, P-TC and P-HDL-C. These results suggest that a lowered intake of vitamin B6 may impair the adaptation of animals to fuel metabolism related to a decrease of fatty acid oxidation and attenuates the exercise-traning effect on blood lipid profile.

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Dietary Sesame Meal Increases Plasma HDL-cholesterol Concentration in Goats

  • Hirano, Y.;Kashima, T.;Inagaki, N.;Uesaka, K.;Yokota, H.;Kita, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.11
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    • pp.1564-1567
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    • 2002
  • Influence of dietary sesame meal on plasma glucose, non-esterified fatty acid (NEFA), triglyceride, total cholesterol, high-density lipoprotein (HDL)-cholesterol and urea concentrations in goats was examined. Goats were fed a control diet (50% timothy hay and 50% concentrates) (CD) or a sesame meal diet (50% timothy hay, 25% concentrates and 25% sesame meal) (SMD) during 12 days. Blood samples were taken after overnight fasting and afternoon every day. Body weight was not changed by feeding either CD or SMD. The concentrations of plasma triglyceride and urea were higher (p<0.05) in goats fed SMD than those fed CD. Plasma NEFA concentration was higher in plasma samples after overnight fasting. Plasma glucose concentration in plasma samples collected afternoon was higher than those after overnight fasting. Plasma total cholesterol concentration was significantly increased by feeding SMD but not by feeding CD, which was due to the remarkable increase of plasma HDL-cholesterol concentration. In conclusion, dietary sesame meal brought about an increase in plasma total cholesterol concentration accompanied with an increment in plasma HDL-cholesterol consentration in goats.

Some Factors Affecting Lipid Metabolism (지질대사(脂質代謝)에 관여하는 인자(因子))

  • Nam, Hyun-Keun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.15 no.2
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    • pp.191-200
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    • 1986
  • It is now generally accepted that individuals at increased risk for cardiovascular disease may be identified by certain traits or habbits. The factors such as high blood pressure, elevated blood cholestrol, age, sex and obesity are associated with increseaed frequency of disease. The blood cholesterol level lowering will decrease cardiovascular disease risk. The regression of atherosclerosis can be achieved by lowering the level of circulating cholesterol. Those things are connected with the quantity and quality of protein, fats, carbohydrates, especially soluble and non-soluble fiber, magnesium and calcium. The lipoprotein and lipid metabolism are connected with the lipid transport. The factors on lipid absorption and blood serum lipid pattern of human are exist. The factors have a variety of materials with different chemical and physical properties. The soluble fiber diet make a low blood and liver lipids. Many kind of soluble fiber results in a lowering of blood cholesterol and triglyceride levels. The cholesterol lowering effects of dietery fiber may be a results of alterations of in intestinal handling of fats, hepatic metabolism of fatty acid or triglyceride acid metabolism of lipoprotein. It is investigated that the high density lipoprotein (HDL) is inversely related to coronary artery disease. It has been postulated that HDL may be an important factor in cholesterol efflux from the tissues, therby reducing the amount of cholesterol deposited there. Alternatively, the HDL may pick up cholestyl ester and phospholipid during normal VLDL lipolysis in the plasma. The HDL levels are relatively insensitive to diet. At present time, the cause-and -diet effect of HDL's inverse relation to CHD remains unclear.

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A Korean Family with Cholesterol Ester Transfer Protein Deficiency

  • Youn, Seo-Young;Shin, Ik-Soon;Hong, Yong-Hee;Lee, Dong-Hwan
    • Journal of Genetic Medicine
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    • v.9 no.1
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    • pp.38-41
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    • 2012
  • A 32-year-old female patient and her sister show high levels of high density lipoprotein (HDL) cholesterol in regular health checkups, since female patient was 11 years old. The patient's serum total cholesterol was 285 mg/dL and HDL cholesterol was 113 mg/dL. Her sister's total cholesterol was 240 mg/dL and the HDL cholesterol measured to be 90 mg/dL. Lipoprotein pattern and cholesteryl ester transfer activity gene analysis were examined in these patients. We found c.1321+1G>A (IVS14+1G/A) hetero mutation in cholesteryl ester transfer protein (CETP) genes. Generally, CETP mediates transfer and exchange of triglycerides and cholesteryl ester between plasma lipoproteins. Also we investigated a key role of HDL-CE and Apo A-1 metabolism. Patients with low levels of CETP have increased serum HDL levels. We hereby report two Korean cases of CETP deficiency in a family. Brief literature review ensues with the cases.

Physical Fitness, Leisure Time Physical Activity, and Serum Lipid Levels in Middle-Aged Male Workers (중년 남성 근로자에서 신체 적합도, 여가중 신체 활동과 혈중 지질 농도)

  • Kim, Jang-Rak;Nam, Bock-Dong;Kim, Ju-Ho;Lee, Song-Kwon;Moon, Joong-Kap;Lee, Jang-Ho;Hong, Dae-Yong
    • Journal of Preventive Medicine and Public Health
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    • v.29 no.2 s.53
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    • pp.173-186
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    • 1996
  • This is a cross-sectional study to evaluate the relationships between physical fitness, leisure time physical activity, and serum lipid levels in middle-aged male workers. Physical fitness was measured by a step test score, and leisure time physical activity was self-reported on a questionnaire. Serum total cholesterol was negatively related to physical fitness(r=-0.27), and positively to obesity index(r=0.27). But leisure time physical activity was related to total cholesterol negatively(r=-0.20) only in subjects whose total cholesterol levels were above 170mg/dl. High density lipoprotein(HDL) cholesterol was positively related to physical fitness(r=0.15), negatively to obestiy index(r=-0.22), and positively to weekly alcohol consumption(r=0.14). Total cholesterol/HDL cholesterol ratio was related to physical fitness(r=-0.23), obesity index(r=0.32), total cigarette index (r=0.13), weekly alcohol consumption(r=-0.13), and vegetable preference(r=0.13). Physical fitness was also related to leisure time physical activity(r=0.19) and obesity index(r=-0.18). In multiple linear regression models, physical fitness(beta=-0.23) and obesity index(beta=0.18) were significantly associated with total cholesterol, obesity index(beta=-0.25) with HDLcholesterol, and obesity index(beta=0.30), physical fitness(beta=-0.16) and vegetable preference (beta=0.14) with total cholesterol/HDL cholesterol ratio. In conclusion, as physical fitness has a stronger relationship with serum lipid levels than leisure time physical activity, and the association between physical fitness and leisure time physical activity is modest, physical fitness should be added as an important variable in addition to activity in future epidemiologic studies.

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Design of an 8-bit Color Adjustor for SDTV Using Verilog HDL (Verilog HDL을 이용한 SDTV용 8bit 색상 보정기의 설계)

  • Jeon, Byoung-Woong;Song, In-Chae
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.801-804
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    • 2005
  • In this paper, we designed an 8-bit color adjustor for SDTV using Verilog HDL. The conversion block requires a lot of multiplication. So we adopted Booth algorithm to reduce amount of operation and processing time. To improve speed, we designed the system output as parallel structure. We synthesized the designed system using Xilinx ISE and verified the operation through simulation using Modelsim.

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Magnetic Immuno-separation 방법을 이용한 HDL Cholesterol 측정시스템 개발

  • Jo, Jeong-Hwan;Chae, U-Cheol;Baek, Se-Hwan
    • 한국생물공학회:학술대회논문집
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    • 2001.11a
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    • pp.833-834
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    • 2001
  • A membrane immuno-chromatographic system that selectively separated plasma lipoproteins and generated a signal in proportion to the concentration of cholesterol within high-density lipoprotein (HDL) was investigated as a point-of-care device for the prognosis of coronary heart disease.

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