• Title/Summary/Keyword: HDL

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3X Serial GF(2m) Multiplier on Polynomial Basis Finite Field (Polynomial basis 방식의 3배속 직렬 유한체 곱셈기)

  • 문상국
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2004.05b
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    • pp.255-258
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    • 2004
  • Efficient finite field operation in the elliptic curve (EC) public key cryptography algorithm, which attracts much of latest issues in the applications in information security, is very important. Traditional serial finite multipliers root from Mastrovito's serial multiplication architecture. In this paper, we adopt the polynomial basis and propose a new finite field multiplier, inducing numerical expressions which can be applied to exhibit 3 times as much performance as the Mastrovito's. We described the proposed multiplier with HDL to verify and evaluate as a proper hardware IP. HDL-implemented serial GF (Galois field) multiplier showed 3 times as fast speed as the traditional serial multiplier's adding only Partial-sum block in the hardware.

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Effect of Cnidi rhizoma Water-Extracted Solution on Fat Contents in Plasma, Liver and Adipose, and Fecal Steroids of Fatted Rats (천궁의 열수 추출액이 고지방식이에 의한 흰쥐의 혈장, 간 및 지방조직의 지질함량과 분변 Steroids에 미치는 영향)

  • Seong, Tae-Su;Son, Gyu-Mok;Bae, Man-Jong
    • The Korean Journal of Food And Nutrition
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    • v.7 no.2
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    • pp.100-107
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    • 1994
  • This study was carried out to evaluate the effect of Cnidi rhizoma (CR) water extract on fat accumulation in fatted rats induced by the oral high fat administration for six weeks. Total cholesterol, neutral lipid and epididymal fat pad of CR groups were lower than the control group. On the other hand, high density lipoprotein(HDL) -cholesterol was somewhat higher In CR than In the control group. In addition, the same result as the above case was obtained when examining adipose for liver and epididymal fat components. During the feeding experiment, level of low density Lipoprotein(LDL) and very low density Lipoprotein (VLDL) increased while HDL was decreased. The degree of LDL and VLDL was decreased however, and HDL was, increased In CH groups as compared with the control group. Insulin and cortisol were higher than the control group, due to the fat accumulation. Experiment group showed the increased excretion as compared with the control group, in the excretion of bile acid and neutral sterol. The liver of the control group observed by the light microscope appeared to the fatty liver, but CR groups showed some improvement of the fatty liver. Based on the above results, it was shown that It Is possible to improve fat accumulation induced, by high fat dietary through using the oral administration of Cnidi rhizoma boiling extract solutions.

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A Case Report on Enhanced Lipid Metabolism by Soluble Dietary Fiber Supplementation during the Gamrosu Modified Fasting Therapy Period (감로수 절식요법기에 수용성 식이섬유를 공급하여 지질대사가 개선된 증례)

  • Shin, Seung-Uoo;Kim, Dong-Hwan
    • Journal of Korean Medicine for Obesity Research
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    • v.17 no.2
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    • pp.140-144
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    • 2017
  • A highly obese female patient (body mass index=$30.8kg/m^2$) participated in a 10-day Gamrosu modified fasting therapy with soluble dietary fiber supplementation to enhance lipid metabolism. Gamrosu is a modified fasting therapy beverage which is made from medical herbs and carbohydrates (431 kcal/d). Before and after fasting, we evaluated the efficacy of therapy by measuring the changes of body composition and blood chemistry. After the modified fasting therapy, -6.1% of body weight and -5.6% of body fat mass were decreased. With regard to blood chemistry, all the plasma lipid levels were lowered. -37.4% of total cholesterol, -39.7% of low density lipoprotein cholesterol, -39.0% of triglyceride and -27% of high density lipoprotein (HDL) cholesterol were reduced. Further studies are needed to alleviate the reduction of HDL-cholesterol to apply the Gamrosu modified fasting to hyperlipidemia.

Improving the prediction accuracy for LDL-cholesterol based on semi-supervised learning (준지도학습 기반 LDL-콜레스테롤 예측의 정확도 개선)

  • Yang, Su-Bhin;Kim, Min-Tae;Kwon, Su-Bin;Woo, Na-Hyun;Kim, Hak-Jae;Jeong, Tai-Kyeong;Lee, Sung-Ju
    • Annual Conference of KIPS
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    • 2022.05a
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    • pp.553-556
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    • 2022
  • 이상지질혈증의 발병에 대한 조기 진단 및 관리하는 것은 중요한 문제이다. 이상지질혈증의 진단은 혈액계측 정보 중에서 네 가지 LDL, HDL, TG, 그리고 TC를 이용하여 진단하며, 이상지질혈증 관리를 위해서는 LDL을 추정하는 것이 중요하다. 본 논문에서는 나이, 성별, 그리고 BMI와 같은 신체계측 정보를 학습하여 LDL-콜레스테롤을 예측하기 위한 준지도학습(Semi-supervised learning) 기반 기계학습 방법을 제안한다. 제안 방법은 얕은 학습(Shallow Learning)기반의 MLP(Multi-Layer Perceptron)을 이용하고, 이상지질혈증 진단인자간의 상관관계를 고려하여 신체계측 정보로 예측된 HDL, TG, 그리고 TC을 이용하여 일반적인 기계학습을 이용한 예측방법의 정확도를 개선한다. 즉, 제안방법은 신체계측 정보를 이용하여 혈액계측 정보의 LDL, HDL, TG, 그리고 TC을 각각 예측하고, 신체계측에 혈액계측의 예측 정보를 추가하여 학습한 준지도학습 기반 얕은 네트워크를 설계한다. 실험결과, HDL, TG, 그리고 TC의 혈액예측 정보를 이용한 준지도학습 기반 LDL 예측 정확도는 71.4%로 신체계측 정보만을 이용한 예측 방법의 67.0% 보다 약 4.4% 개선할 수 있음을 확인한다.

FPGA Performance Evaluation According to HDL Coding Style (HDL 코딩 방법에 따른 FPGA에서의 성능 실험 및 평가)

  • Lee, Sangwook;Lee, Boseon;Lee, Seungeun;Suh, Taeweon
    • Annual Conference of KIPS
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    • 2011.11a
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    • pp.62-65
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    • 2011
  • FPGA는 대용량의 게이트를 지원하는 하드웨어를 프로그램 할 수 있는 디바이스이다. ASIC을 위해 설계된 로직은 칩으로 제조되기 전에 검증 과정을 거친다. 이 검증 과정에서 시뮬레이션의 한계를 극복하기 위해 FPGA를 사용한 에뮬레이션 방법을 많이 채택한다. 에뮬레이션 과정에서 ASIC의 동작 속도로 검증하는 것이 바람직하지만 FPGA의 특성상 ASIC과 같은 속도로 동작하기는 쉽지 않은 것이 현실이다. 본 논문에서는 HDL 코딩 방법에 따른 FPGA의 성능 민감도를 실험하였다. 실험 및 평가를 위해 다양한 알고리즘을 가진 가산기를 이용하였고 각 가산기 종류와 비트수에 따라 Verilog-HDL을 이용하여 코딩하였으며 대표적인 FPGA 제조사(Altera와 Xilinx)별, 디바이스별로 동작 속도와 자원 사용량을 측정하였다. 실험 결과 FPGA 제조사별로 다른 경향을 보임을 확인하였다. 성능 면에서는 비트별로 다소 차이는 있지만 Altera 디바이스에서는 Ripple Carry, Carry Lookahead 가산기보다 Prefix 가산기의 성능이 우수하게 나왔다. Xilinx 디바이스에서는 예상과 달리 가산기들 사이의 성능 차이가 크게 나지 않았으며 Ripple Carry, Carry Lookahead 가산기가 Prefix 가산기보다 높은 성능을 보이는 경우도 있었다. 비용 면에서는 디바이스별로 큰 차이가 나지 않았으며 ASIC과 비슷한 성능 민감도를 보였다. 그리고 각 제조사에서 제공하는 IP(Intellectual Property) Core를 사용했을 경우는 대부분의 디바이스에서 우수한 성능을 보여 주었다. TSMC 90nm 공정 기술로 제작한 ASIC과 IP Core를 비교했을 때는 ASIC의 성능이 4배 정도 우수한 것으로 나타났다.

Polyunsaturated/saturated Fatty Acid Ratios and Antioxidant Supplementation under the Control of Dietary Peroxidizability Index Value: Impact on Serum Lipid Profiles in Young and Adult Rats

  • Kang, Min Jeong;Lee, Eun Kyung;Lee, Sang Sun
    • Nutritional Sciences
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    • v.8 no.1
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    • pp.10-15
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    • 2005
  • An increase in serum cholesterol is directly associated with high incidences of cardiovascular diseases (CVD) and atherosclerosis. Serum lipid profiles are highly dependent on dietary fatty acids and age. The purpose of this study was to examine the age-related effects of polyunsaturated/saturated fatty acid ratios and antioxidant supplementation under the control of the dietary peroxidizability index (PI) value on serum lipid profiles in rats. While the PI level of dietary fatty acids was controlled at 81.22, the P/S ratios of fatty acids were 0.38 and 4.81 (LP and HP). The diets were supplemented with a vitamin E 1000 mg/kg diet and a selenium 2.5 mg/kg diet (LPS and HPS). Female Sprague-Dawley rats ages 3 weeks (young) and 16 weeks (adult) were fed four different experimental diets for 4 weeks. The serum triglyceride concentration of LPS was significantly higher in young rats than in adult rats. The total-cholesterol concentration of LP and HPS were higher in young rats than in adult rats. The high-density lipoprotein-cholesterol (HDL-C) concentration of LP, LPS and HP was higher in adult rats than in young rats. The low-density lipoprotein-cholesterol (LDL-C) concentration was higher in young rats than in adult rats. T-C/HDL-C and LDL-C/HDL-C ratios were much higher in young rats than in adult rats. In conclusion, P/S ratios and antioxidant supplementation did not affect T-C/HDL-C and LDL-C/HDL-C ratios as risk factors of CVD in adult rats when we controlled the PI value in the diet Probably, the invisible and confounding effects of dietary PI value implicate the beneficial roles of dietary P/S ratios and antioxidants in CVD. Accordingly, controlling the dietary PI value may be advantageous to lower the risk of CVD in adult rats.

The Effects of Exercise Therapy and Exercise-Behavior Modification Therapy on Obesity, Blood Lipids, and Self-esteem of the Obese Middle-aged Women (운동요법, 운동.행동수정요법이 중년 비만여성의 비만도, 혈중지질 및 자아존중감에 미치는 효과)

  • 김인홍
    • Journal of Korean Academy of Nursing
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    • v.32 no.6
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    • pp.844-854
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    • 2002
  • To examine the effect of the exercise therapy, and exercise-behavior modifi- cation therapy on obesity, blood lipids and self-esteem of the obese middle-aged women. Method: A total of 35 middle-aged women (BMI: over 30) were selected for this research. Walking at a 50% intensity was administered 4 days a week for 12 weeks, while the behavior modification therapy performed for 60~90 minutes per week for 12 weeks. Result: Body weight and BMI has significantly reduced in the case of EG and E BG. The result of comparing body weight between groups showed significant difference between EG and CG, and E BG and CG whereas BMI showed significant difference between EG and CG only. TC, TG, LDL-C, %TC/HDL-C have shown significant decrease in EG and E-BG, while HDL-C displayed significant increase in EG and E BG. And HDL-C showed significant decrease in CG. As for comparison between groups, significant difference was noted in EG and CG, and E BG and CG at TC, HDL-C, LDL-C, and in EG and CG at %TC/HDL-C. Self-esteem displayed significant increase in EG and E BG; however, there was no significant different in CG. As for comparison between groups, there was significant difference noted in E BG and CG only. Conclusion: The results showed that the exercise therapy and the exercise-behavior modification therapy were effective in changing obesity, blood lipids and self-esteem of the obese middle-aged women.

Effect of Growth Inhibition in Hep3B cell and HeLa cell by treatment of Euonymus alatus(Thunb.) Sieb extracts (귀전우(鬼箭羽)(Euonymus alatus(Thunb.) Sieb)가 간암세포(肝癌細胞)(Hep3B)와 자궁암세포(子宮癌細胞)(HeLa)의 성장억제(成長抑制)에 미치는 영향(影響)에 관한 연구(硏究))

  • Choi, Dal-Yeong
    • The Journal of Dong Guk Oriental Medicine
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    • v.7 no.2
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    • pp.155-162
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    • 1999
  • Euonymus alatus(Thunb.) Sieb has been used for cancer theraphy such as Liver cancer, esophagus cancer, stomach cancer, and uterine cancer in folk. Eupolyphaga simemsis(ES) extracted from Euonymus alatus(Thunb.) Sieb increases HDL-C/TC ratio and LCAT activity. TGF-${\beta}$ and Insulin has been Knoen as factors to induce the supression of proliferation of Hep3B, Human hepatoblastoma cell. Plasma HDL3-C involved in carbohydrate methabolism in the liver was maintained in low level by Euonymus alatus(Thunb.) Sieb. The low level of plasma HDL3-C suppresses the transition from normal liver to Fat liver. Finally, this resuly in suppression of cancer in liver. In this study, Euonymus alatus(Thunb.) Sieb showed higher cell toxicity in hepatoblastoma cell(Hep3B) compared to the uterine cancer cell(HeLa). This means Euonymus alatus(Thunb.) Sieb seems not to affect in the all kinds of cancer. In future, we will study whether Euonymus alatus(Thunb.) Sleb have an effect on the liver cancer induced by virus and hepatocellular carcinoma. Also, the mechanims of suppression of cell proliferation in HCC need to investigated.

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An Association between Milk Consumption and Serum Lipid Profiles of Postmenopausal Women in Korea (폐경 여성의 우유 섭취와 혈청 지질수준과의 관련성 연구)

  • Lee Sang-Sun;Kim Soon-Lae;Kim Sun-Hee
    • Journal of Nutrition and Health
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    • v.38 no.2
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    • pp.144-150
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    • 2005
  • The aim of this study was to analyze an association between milk consumption and serum lipid profiles in postmenopausal women in Korea. The dietary data by the Food Frequency Questionnaire were evaluated among 208 postmenopausal women who did not receive hormone therapy and their serum concentrations of triglyceride (TG), total, HDL-, and LDL-cholesterol, and alkaline phosphatase were analyzed. When the relationship between milk consumption and serum lipid profiles were analysed by linear regression, we found a negative relationship of milk consumption with ALP and a positive relationship with HDL-cholesterol. Animal calcium intake was significantly correlated with ALP and HDL-cholesterol. In addition, the serum level of HDL-cholesterol of the upper quartile (UQ) subjects who took animal calcium over 313 mg/day was significantly higher than the lower quartile (LQ) subjects who consumed milk below 101 mg/day when we compared the UQ and LQ subjects. The HDL-cholesterol level of the UQ subjects who consumed 235 ml of milk tended to be higher than the that of the LQ who consumed 53 ml. As for serum concentrations of TG, total cholesterol, and LDL-cholesterol, there was no significant difference between the UQ and LQ groups of milk consumption. Based on our study, we concluded that continual consumption of approximately one cup of milk per day was associated with low cardiovascular risks with favorable lipid profiles and ALP in postmenopausal women. (Korean J Nutrition 38(2): 144~150, 2005)

Effects of Factors on Serum Lipid Levels in Suwon Adult Males (수원지역 성인 남성들의 혈청지질 수준에 영향을 미치는 요인)

  • Lee, Hyun-Joo;Cho, Kang-Ok
    • The Korean Journal of Community Living Science
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    • v.19 no.1
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    • pp.113-123
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    • 2008
  • This study was performed to find and compare the characteristics of dietary factors and obesity indices on serum lipid profiles using 407 healthy adult males that had physical examinations conducted at the general hospital located in Suwon. The subjects were divided 56.3% for the normal group, 16.7% for TG, 14.5% for TC and 12.5% for TC TG group, respectively. When comparing the blood lipid profiles to normal group, TC group was high in both total cholesterol and LDL-cholesterol, TG group was high in triglyceride and low in HDL-cholesterol, TC TG group was high in triglyceride, total cholesterol, LDL-cholesterol and low in HDL-cholesterol. In comparison of blood lipid profiles with normal group, among anthropometric factors, body weigh, BMI (Body Mass Index) and WHR (Waist Hip Ratio) showed significant differences. TC group was high in both total cholesterol and LDL-cholesterol, and TG group was high in triglyceride and low in HDL-cholesterol. TC TG group was high in triglyceride, total cholesterol and LDL-cholesterol, and was low in HDL-cholesterol. Body weigh of TG group was significantly higher than that of normal group (p<0.05). BMI and WHR of TG group and TC TG group were significantly higher than those of normal group (p<0.05). Total cholesterol was mainly related to the intake of animal lipids and alcoholic beverage. Serum triglyceride levels were closely related with lipid intake and high BMI in this group. In TC TG group, BMI and WHR were high. As well, serum LDL-cholesterol was high and HDL-cholesterol was low which indicates TC TG group had the most undesirable blood lipid profiles. Therefore, it may be necessary to manage BMI and WHR to prevent hyperlipidemia and obesity for adult males in Suwon.

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