• Proceedings of the KIEE Conference
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• 1996.11a
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• pp.200-202
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• 1996

MgO film was deposited on the glass substrate by the hollow cathode discharge ion plating method and the characteristics of the MgO thin film such as deposition rate, crystalline orientation, surface morphology and secondary electron coefficient were investigated. The deposition rate of MgO thin films were $430^{\sim}1270{\AA}$/min at various temperatures and biases. The crystalline orientation of the MgO thin film changed from (200) to (220) upon increasing the HCD current from 100A to 200A. These results indicated that the crystallin orientation of the MgO thin film was determined by the super-saturation ratio. The (200) peak decreased and the (220) peak increased as the substrate bias increased, while both peaks increased as the substrate temperature increased. The grain size increased as the substrate bias increased and the secondary electron emission coefficient increased as the substrate bias increased.

• Korean Journal of Food Science and Technology
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• v.47 no.5
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• pp.658-666
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• 2015

The aim of this study was to investigate the effects of rice contatining Aspergillus terreus (Hwangkuk, HK) on lipid metabolism in male Sprague-Dawley (SD) rats fed a high-cholesterol diet (HCD) for 8 weeks. SD rats were divided into five groups: Normal, [Negative Control (HCD), Positive Control (lovastatin)], [HK 0.5 g/kg and HK 2 g/kg]. Hepatic total lipids significantly decreased following treatment with rice contatining Asp. terreus. Furthermore, this treatment led to higher expression levels of HMG-CoA reductase, LDL receptor and SREBP2 mRNA in the liver compared with the HCD group. In addition, histopathologic evaluation showed that feeding rats with rice containing Asp. terreus suppressed hepatic steatosis. These results suggest that rice containing Asp. terreus may be able to regulate of cholesterol synthesis and prevent hyperlipidemia.

• Nutrition Research and Practice
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• v.14 no.3
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• pp.175-187
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• 2020

BACKGROUND/OBJECTIVES: In this study, we investigated the beneficial effects of skate cartilage extracts containing chondroitin sulfate (SCS) on hyperlipidemia-induced inflammation and oxidative stress in high cholesterol diet (HCD)-fed mice in comparison with the effects of shark cartilage-derived chondroitin sulfate (CS). MATERIALS/METHODS: Low-density lipoprotein receptor knockout (LDLR-KO) mice were fed HCD with an oral administration of CS (50 and 100 mg/kg BW/day), SCS (100 and 200 mg/kg BW/day), or water, respectively, for ten weeks. RESULTS: The administration of CS or SCS reduced the levels of serum triglyceride (TG), total cholesterol (TC), and LDL cholesterol and elevated the levels of high-density lipoprotein cholesterol, compared with those of the control group (P < 0.05). Furthermore, CS or SCS significantly attenuated inflammation by reducing the serum levels of interleukin (IL)-1β and hepatic protein expression levels of nuclear factor kappa B, inducible nitric oxide synthase, cyclooxygenase-2, and IL-1beta (P < 0.05). In particular, the serum level of tumor necrosis factor-alpha was reduced only in the 100 mg/kg BW/day of SCS-fed group, whereas the IL-6 level was reduced in the 100 and 200 mg/kg BW/day of SCS-fed groups (P < 0.05). In addition, lipid peroxidation and nitric oxide production were attenuated in the livers of the CS and SCS groups mediated by the upregulation of hepatic proteins of antioxidant enzymes, such as superoxide dismutase, catalase, and glutathione peroxidase (P < 0.05). CONCLUSIONS: These results suggest that the biological effects of SCS, similar to those of CS, are attributed to improved lipid profiles as well as suppressed inflammation and oxidative stress induced by the intake of HCD.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.189-190
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• 2016

국제해사기구에서는 사용자 중심의 운항환경 구축을 위해 항해장비에 대한 사용자 요구사항 분석과 사용성 평가의 필요성을 강조하고 있다. 다양한 분야에서 많은 사용성의 평가방법이 연구되어져 오고 있지만, 항해장비 분야의 연구에는 미흡한 실정이다. 본 연구에서는 선교의 다양한 항해장비들 중 ECDIS를 대상으로 실무에서 활용가능한 사용성 평가항목 및 체크리스트를 개발하여 제안하고자 한다.

• Conservation Science in Museum
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• v.14
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• pp.7-12
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• 2013

The conservation has been conducted for the fragments of an wooden boat in the Neolithic Age, excavated from Bibong-ri, Changnyeong, Korea. The vacuum-freeze drying have been applied to mostly to the small relics, such as wooden lacquerwares or small wooden goods etc.. Therefore, the large objects like a wooden boats have been treated almost by air-drying after impregnation with aqueous PEG solution. The air-drying is needed to impregnate with PEG aqueous solution during long period and run the risk of the fault generation. This report explain an example adapted for the fragments of the wooden boat by humidity-controlled drying(HCD) with slow adjusting moisture content. We did the chemical pre-treatment, PEG aqueous solution. The concentration of the aqueous solution was increased gradually from 10% to 80%. After the impregnation, the objects were dried by the HCD. The dimensional stability of the fragments after treatment was good.

• Animal Bioscience
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• v.36 no.1
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• pp.53-62
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• 2023

Objective: In this study, metabolites that changed in the rumen fluid, urine and feces of dairy cows fed different feed ratios were investigated. Methods: Eight Holstein cows were used in this study. Rumen fluid, urine, and feces were collected from the normal concentrate diet (NCD) (Italian ryegrass 80%: concentrate 20% in the total feed) and high concentrate diet (HCD) groups (20%: 80%) of dairy cows. Metabolite analysis was performed using proton nuclear magnetic resonance (NMR) identification, and statistical analysis was performed using Chenomx NMR software 8.4 and Metaboanalyst 4.0. Results: The two groups of rumen fluid and urine samples were separated, and samples from the same group were aggregated together. On the other hand, the feces samples were not separated and showed similar tendencies between the two groups. In total, 160, 177, and 188 metabolites were identified in the rumen fluid, urine, and feces, respectively. The differential metabolites with low and high concentrations were 15 and 49, 14 and 16, and 2 and 2 in the rumen fluid, urine, and feces samples, in the NCD group. Conclusion: As HCD is related to rumen microbial changes, research on different metabolites such as glucuronate, acetylsalicylate, histidine, and O-Acetylcarnitine, which are related to bacterial degradation and metabolism, will need to be carried out in future studies along with microbial analysis. In urine, the identified metabolites, such as gallate, syringate, and vanillate can provide insight into microbial, metabolic, and feed parameters that cause changes depending on the feed rate. Additionally, it is thought that they can be used as potential biomarkers for further research on subacute ruminal acidosis.

• Journal of the Korean institute of surface engineering
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• v.28 no.5
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• pp.267-275
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• 1995

Electron beam can provide convenient way to heat the substrate during Hollow Cathode Discharge (HCD) ion plating of Ti(C, N)films. Densification of columnar structrue is enhanced by longer duration of electron beam heating(EBH). While strong(111) texture is identified always to be formed, the amount of (200) oriented grains which coherently interfaced with carbide particles of the substrate increased with heating(EBH). In turns, these crystallogaphical change lead to the increase of micro hardness and adhesion of coating. Adhesion of Ti(C, N) films increased more dramatically in case of ASP30 substrate of which carbide particles dispersed more finely than M42. Therefore, it could be concluded that both the density of film and interfacial structure can affect the adhesion property. Overheating of substrate could be resulted in low adhesion resistance due to high residual stress developed in the film.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.35-37
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• 2016

최근 IMO에서는 e-Navigation IT서비스를 사용자 입장에서 평가하도록 인간중심설계(HCD, Human Centered Design) 활동에 기반을 둔 유용성 평가에 대하여 표준화 작업을 진행하고 있다. 만약 IT서비스를 유용성 평가 기법으로 수행한다면 문제점, 오류, 개선사항, 사용자 요구사항 등을 도출할 수 있다. 그러나 IT서비스에 대한 유용성 평가의 관련 연구는 거의 진행되지 않고 있다. 이유는 최근 국제표준 제정을 준비하고 있고 평가를 위한 도구 및 평가 척도, 방법에 대한 기준이 명확하지 않기 때문이다. 따라서 본 연구에서는 경로 계획 공유(Route Plan Exchange) e-Navigation IT서비스에 대하여 유용성 평가 과정을 수행하였다. 유용성 평가를 위해 평가도구, 평가 시나리오, 평가 척도, 평가 방법을 개발하고 항해사 대상으로 유효성(Effectiveness), 효율성(Efficiency), 만족성(Satisfaction)을 평가하였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.186-188
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• 2016

전자항법시대의 도래로, 항해사의 의사결정시 항해설비 의존도는 점차 증가하고 있으며, 국제협약에 의해 ECDIS(전자해도 정보시스템)의 강제화로 전자항해설비 사용을 위한 친숙화는 필수적이다. 국제사회에서도 항해사 및 도선사들이 항해설비의 친숙한 사용을 도모하기 위한 표준이 필요함을 인식하고, 2015년 6월 IMO MSC 95차에서 항해설비에 표준모드 적용을 위한 S-Mode 가이드라인 개발이 2019년까지의 e-Navigation 주요개발 과제로 승인되었다. S-Mode는 주요 사용자인 항해사, 선장 및 도선사에게 표준화된 화면, 기능 제공을 통해 친숙한 업무환경을 통해 상황인식에 기여함으로써 항해안전성을 향상시키고, 교육 훈련 측면에서의 선원의 부담을 경감시키기 위한 목적으로 개발 예정이다. S-Mode 가이드라인 개발을 위해서, HCD(인간중심적 설계)에 기반 하여, 항해설비에 대한 인적측면에서의 개선이 이루어질 것으로 예상된다. 본 연구에서는 ECDIS를 활용하여 S-Mode 가이드라인 개발을 위한 주요 방안 및 항해화면의 개선방안을 연구하였다.

• Journal of the Korean Vacuum Society
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• v.11 no.2
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• pp.119-126
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• 2002

The optogalvanic signals were measured using hollow cathode discharge tube with argon as buffer gas at change of discharge currents. A change of ionization rate due to electron collision causes an increase or decrease of the electric conductivity, This change in electric conductivity generates the optogalvanic signal. We conclude that optogalvanic signal has close relation with change of the lowest metastable atoms density at low current.