• Title/Summary/Keyword: HBC

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A Case-Control Study on Association Between Hepatocellular Carcinoma and Infection of Hepatitis B and Hepatitis C Virus (B형간염바이러스 및 C형간염바이러스의 표식자 양성율과 원발성 간세포 암의 연관성에 대한 환자-대조군 연구)

  • Ahn, Hyeong-Sik;Kim, Min-Ho;Kim, Young-Sick;Kim, Joung-Soon
    • Journal of Preventive Medicine and Public Health
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    • v.30 no.1 s.56
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    • pp.1-15
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    • 1997
  • To investigate the association between hepatocellular carcinema(HCC) and infection of hepatitis B virus(HBV) and hepatitis C virus(HCV) in an HBV endemic area, a case-control study of 254 patients with HCC and of 1,270 age and sex matched health control subjects was done. Among the 254 HCC patients 166(65.4%) were positive for hepatitis B surface antigen(HBsAg), 49(19.3%) were positive for HCV antibody (anti-HCV Ab). The crude odd ratio of patients with HBsAg was 36.1(95% CI :22.4-58.2) and with anti-HCV Ab was 9.0(95% CI :5.5-14.6). In an analysis, which HBsAg(-), HBcAb(-), anti-HCV Ab(-) group was chosen as referent group, odd ratio of HBsAg(+) group was 14.4(95% CI: 7.2-28.9) and of anti- HCV Ab(+) was 10.7(95% CI: 2.9-40.0). odd ratio of anti-HCV Ab(+), HBsAg(+) group and anti-HCV Ab(+), HBsAg(-), HbcAb(+) group for HCC were elevated to 27.3(95% CI : 9.0-82.9), 15.9(95% CI:7.1-35.8) respectly, The odd ratio of anti-HCV Ab(-), HBsAg(-), HBcAb(+) group was 2.4(95% CI : 1.1-5.0). These result suggested that HBV and HCV were associated with HCC. In HBV endemic area patients with HBcAb alone should be considered risk group for HCC.

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Preliminary Result from Rapid Cadence Photometric Monitoring of HBC722

  • Baek, Gi-Seon;Green, Joel D.;Pak, Soo-Jong;Lee, Jeong-Eun;Eon, Yi-Seulj;Park, Won-Kee;Choi, Chang-Su;Kang, Won-Seok;Im, Myung-Shin
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.113.2-113.2
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    • 2011
  • We observed a low-mass pre-main sequence star, HBC722 (also known as $LkH{\alpha}$ 188 G4), with Camera for QUasars in EArly uNiverse (CQUEAN) attached to 2.1 Otto Struve telescope at McDonald Observatory, USA. HBC722 is a new FU orionis-type object in the direction of NGC7000/IC5070, which produced large amplitude optical outbursts (${\delta}V$=4.7 mag over one year) for a few months and reached the peak in 2010 September. We carried out the photometric observation in SDSS r,i, and z band in 2011 April, July and August to monitor the long term decrease of its brightness. We also made continuous observation in r-band for half night in July, and whole two nights in August to investigate short term variability which could be related to the rotation of the central star or the inner circumstellar disk. In this poster, we present a preliminary result of the photometric observation for HBC722.

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Variability Analysis of HBC722 using Lomb-Scargle Periodogram

  • Baek, Giseon;Pak, Soojong;Green, Joel D.;Jeon, Yiseul;Choi, Changsu;Lee, Jeong-Eun;Im, Myungshin;Meschiari, Stefano
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.52.1-52.1
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    • 2013
  • We present preliminary results of the photometric variability analysis in SDSS r, i and z bands for a newly confirmed FU Orionis-type object, HBC 722. We observed HBC 722 from 2011 April to 2012 November, with Camera for Quasars in Early uNiverse (CQUEAN) attached to the 2.1m Otto Struve telescope at McDonald Observatory, USA. The rapid cadence monitoring observations (minute timescale) were conducted in chosen photometric nights during observation campaigns to get adequate number of samples for short term period analysis. As this object is in active state, temperature at the inner disk/stellar surface can be characterized by the colors between r, i and z bands. Also, It is theorized that a sudden cataclysmic accretion associated with FU Orionis-type outburst can give rise to detectable "hot spots" on the central star and rotational asymmetries in the disk instability region. Thus the periodic variabilities of three bands would trace the stellar rotation or Keplerian rotation at the instability region of the inner accretion disk. Additionally, the range of instabilities could be estimated on the assumption of a temperature distribution for the HBC 722 disk. This analysis can provide a clue for understanding enhanced disk accretion of Class II young stellar object.

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Analysis of Human Body Channel Based on Impulse Response Signals (임펄스 응답 신호를 이용한 인체 채널 분석)

  • Kang, Taewook;Lee, Jae-Jin;Oh, Wangrok
    • Journal of IKEEE
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    • v.26 no.1
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    • pp.36-42
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    • 2022
  • This study presents an analysis of the human body channel as an electric signal path using body impulse response (BIR). The human body communications (HBC) has recently emerged as an effective signal transmission method to create wireless body area networks (WBAN). We provide body channel characteristics based on measured BIR in a proper experimental environment for the HBC using capacitive coupling with a customized channel sounding device, which can be applied as a guideline for the HBC system design. The frequency response of the BIR, extracted by a customized signal processing for the measure signals, shows the channel path loss (CPS) between 0 MHz and 100 MHz with an average CPS of approximately 46.8 dB. In addition, the relative noise power distributions can provide estimations on the signal to noise ratio at the HBC receiver in terms of capacitor and resistor values in the measured frequency band and the frequency band lower than 3 MHz considering the baseband signal detection.

Clinical Significance on the Serologic Profiles of HBV Markers in Various Liver Diseases (각종(各種) 간질환(肝疾患)에서의 B형(型) 간염(肝炎) Virus 표식자(標識子) 발현(發顯)에 대한 임상적(臨床的) 고찰(考察))

  • Yu, Byung-Hee;Lee, Choong-Kyu;Kim, Jong-Hwa;Kim, Kwang-Ill;Lee, Chong-Suk
    • The Korean Journal of Nuclear Medicine
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    • v.17 no.2
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    • pp.49-55
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    • 1983
  • By radioimmunoassay, serologic markers of Hepatitis B Virus were studied in 44 patients with acute viral hepatitis, 10 patients with chronic persistent hepatitis, 10 patients with chronic active hepatitis, 44 patients with liver cirrhosis and 25 patients with primary hepato cellular carcinoma. The results were follows: 1) HBsAg was present in 77.2% of AVH, 40% of CPH, 80% of CAH, 55.1% of LC and 68 % of PHC. In this HBsAg positive groups, all but one in liver cirrhosis had Anti-HBc. 2) Anti-HBs was most commonly detected in CPR and accompanied by Anti-HBc except one case in AVH. 3) Anti-HBc was the only marker detected in 11.4% of AVH, 20% of CPH, 20% of CAH, 16.3% of LC and 8% of PHC. 4) HBeAg was most commonly found in HBsAg-positive CPH but Anti-HBe was most frequently detected in PHC. 5) The absence of HBV markers was noted in 2.3% of AVH, 10% of CPH, 8% of PHC except CAH and LC.

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Post-outburst observation of HBC722 in Pelican nebula

  • Yang, Yuna;Park, Won-Kee;Sung, Hyunil;Lee, Sanggak;Yoon, Tae-Seog;Lee, Jeongeun;Kang, Wonseok;Park, Keunhong;Cho, Dong-Hwan
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.59.1-59.1
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    • 2013
  • HBC722 (also known as LkHa 188-G4 and PTF 10qpf; A. Miller et al., 2011) is one of the FU Orionis-like young stellar objects which outbursted in August 2010 (Semkov et al., 2010). We have been monitoring the post-outburst phase of this object since November 2010 with Korean Astronomy and Space Science Institute Near Infrared Camera System (KASINICS), at Bohyunsan Optical Astronomy Observatory (BOAO). Four filters, J, H, Ks, and H2 band, were used for this observation. We did aperture photometry to find photometric variation. The light curve shows a long period brightness change. After decrease of the brightness, which was reported at the KAS 2011 fall meeting, HBC722 brightens up slowly now. However we cannot confirm any short period variations, previously reported by Green et al (2013), due to large scatters in the obtained light curve.

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The Color Variability Monitoring of HBC722

  • Baek, Giseon;Pak, Soojong;Green, Joel D.;Kang, Wonseok;Jeon, Yiseul;Choi, Changsu;Lee, Jeong-Eun;Im, Myungshin
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.103.1-103.1
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    • 2012
  • We present the results of SDSS r, i and z band photometry for HBC722 (also known as $LkH{\alpha}$ 188 G4, PTF10qpf and V2493 Cyg), with Camera for Quasars in Early uNiverse (CQUEAN) attached to 2.1m Otto Struve telescope at McDonald Observatory, USA. HBC722 is a newly erupted FU Orionis type object, which produced optical outburst (${\Delta}V$=4.7 mag) over a year that peaked in 2010 September. We carried out the monitoring observations during 48 nights from 2011 April to 2012 June to check the short-term and the long-term variabilities for chasing the Keplerian rotation of the system. Comparing the photometric results of r, i and z band, we describe the color variability which is related to the physical properties of the system like circumstellar disk and accretion process.

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Seroepidemiology of Hepatitis A and Hepatitis B in Korean Children (학동기 아동에서 A형 및 B형 간염의 혈청학적 역학조사 -1998년 현재 서울 일부지역을 대상으로-)

  • Ko, Jae-Sung;Bae, Sun-Hwan;Chung, Ju-Young;Chung, June-Key;Seo, Jeong-Kee
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.2 no.1
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    • pp.40-45
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    • 1999
  • Purpose: The aim of this study is to investigate the seroepidemiology of hepatitis A and hepatitis B in Korean children. Methods: 801 children aged 6 to 12 years were enrolled. IgG antibody to hepatitis A virus (anti-HAV), hepatitis B surface antigen (HBsAg), antibody to HBsAg (anti-HBs), and IgG antibody to HBc (anti-HBc) were measured by radioimmunoassay. Results: Of the 801 children, the seroprevalence of anti-HAV was 0%. Three (0.4%) were seropositive for HBsAg. The seroprevalence of anti-HBs was 61.8%. Two (0.4%) of 495 anti-HBs positive subjects were positvie for anti-HBc. Of the 801 children, 658 (82.1%) had received hepatitis B vaccination. Conclusions: Since natural anti-HAV is not acquired in the childhood, the outbreak of hepatitis A is possible in adolescents and young adults. The decrease in seroprevalence of HBsAg and the increase in seroprevalence of anti-HBs might result from hepatitis B vaccination program in childhood.

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Biological Control of Root-knot Nematode by Lysobacter capsici YS1215 (Lysobacter capsici YS1215를 이용한 뿌리혹선충(Root-knot nematode)의 생물학적 방제)

  • Lee, Yong-Sung;Park, Yun-Suk;Kim, Sun-Bae;Kim, Kil-Yong
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.2
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    • pp.105-111
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    • 2013
  • The experiments were carried out to investigate the biocontrol potential of Lysobacter capsici YS1215 on root-knot nematode and to characterize its lytic enzyme activities. L. capsici YS1215 showed chitinase and gelatinase activities on the medium containing 0.5% chitin or 0.5% gelatin as substrates. Cell growth of L. capsici YS1215 was highest at 6 days, and the highest activities of chitinase (4.0 unit $ml^{-1}$) and gelatinase (7.43 unit $ml^{-1}$) were observed on 3 and 5 days after incubation, respectively. To investigate the effect of L. capsici YS1215 on tomato growth and nematode infection, the plants in pot trial were treated with bacterial culture (BC), half of bacterial culture (HBC), only bacterial medium (BM), tap water (TW) and commercial nematicide (CN). HBC treatd plants showed the higher shoot fresh weight and dry weight on $5^{th}$week after incubation while BM, HBC and BC had consistently higher values than TW at $9^{th}$ week. HBC appeared to be the highest shoot fresh length at $9^{th}$ week. Both CN and BC showed lower number of egg mass, root gall, and population of juveniles in soil compared to BC, HBC, BM and TW. These results suggest that L. capsici YS1215 with its strong ability of lytic enzyme production can be one of the most significant candidates for biocontrol agents against root-knot nematodes.

Efficacy of Hepatitis B Immune Globulin for Prevention of De Novo Hepatitis B in Living-related Liver Transplantation (생체 부분 간이식에서 De Novo Hepatitis B에 대한 B형 간염 면역글로불린의 예방적 효과)

  • Kim, Sang-Jong;Hwang, Soo-Jung;Park, Sung-Eun;Choe, Yon-Ho;Lee, Suk-Koo;Joh, Jae-Won;Kim, Sung-Joo;Lee, Kwang-Woong;Seo, Jeong-Meen
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.6 no.1
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    • pp.32-38
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    • 2003
  • Purpose: Hepatic allografts from donors with hepatitis B core antibody have been demonstrated to transmit hepatitis B virus (HBV) infection to recipients after liver transplantation (LT). The efficacy of hepatitis B immune globulin (HBIg) to prevent de novo hepatitis B was investigated by comparing active immunization in the early phase to HBIg monotherapy in the late phase of pediatric liver transplants at Samsung Medical Center. Methods: Among pediatric liver transplants, from May, 1996 to June, 2002, 15 recipients who were hepatitis B surface antigen (HBsAg) (-) received an allograft from a donor with hepatitis B core antibody (HBcAb) (+). Except two who died from unrelated causes, eleven of 13 recipients were HBsAb (+), and 2 were naive (HBsAb(-), HBcAb(-)). All patients were vaccinated for HBV before LT. In the early phase (January, 1997~November, 1997, 3 patients), HBsAb (+) recipients received booster vaccination after LT. In the late phase (December, 1997~, 10 patients), all recipients were given booster vaccination and received HBIg therapy in order to maintain HBsAb titer greater than 200 IU/L. Lamivudine was given in one case because of severe side effect of HBIg. We retrospectively analyzed the effect of the preventive therapy for de novo hepatitis B through medical records. Results: De novo hepatitis B developed in three of 13 recipients (23.1%). All of 3 patients who received active immunization in the early phase became HBsAg (+) at 7~19 months after transplantation. One of them was naive before LT and the other two were HBsAb (+). All of 10 recipients who were given HBIg in the late phase remained HBsAg (-) at 7~55 months' follow-up. Conclusion: Passive immunization with HBIg was effective for prevention of de novo hepatitis B in HBsAg (-) recipients of hepatic allografts from HBcAb (+) donors.

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