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Quantitative Analysis of the Marker Components in Glycyrrhizae Radix et Rhizoma by Processing Method (포제(炮製)에 따른 감초 중 liquiritin, glycyrrhizin 및 glycyrrhetinic acid의 함량분석)

  • Seo, Chang-Seob;Kim, Jung-Hoon;Shin, Hyeun-Kyoo;Hwang, Seock-Yeon;Kim, Byoung-Soo
    • Journal of Haehwa Medicine
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    • v.23 no.1
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    • pp.93-104
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    • 2014
  • Glycyrrhizae Radix et Rhizoma has been extensively used by human beings as a medicinal herb as well as natural sweetener. In this study, we performed quantification analysis of three major constituents including liquiritin, glycyrrhizin, and glycyrrhetinic acid in the 70% ethanol extracts of non-processed Glycyrrhizae Radix et Rhizoma and processed Glycyrrhizae Radix et Rhizoma using a high-performance liquid chromatography coupled with photodiode array detector. The analytical column for separation of the 3 constituents used a Gemini C18 column kept at $40^{\circ}C$ by the gradient elution of two mobile phase. The amounts of liquiritin, glycyrrhizin, and glycyrrhetinic acid in non-processed Glycyrrhizae Radix et Rhizoma were 2.57%, 3.52%, and not detected. After processing by roasting, the best roasting temperature and time of iquiritin, glycyrrhizin, and glycyrrhetinic acid were $160^{\circ}C$-15 min (2.46%), $160^{\circ}C$-15 min (3.67%), and $240^{\circ}C$-15 min (0.76%), respectively.

Methods for Improving the Applicability of Wood Powder Spacers to Liner Board Manufacturing (산업용지 제조에서 목질계 스페이서의 적용성 개선방안)

  • Yoon, Do-Hyun;Sung, Yong Joo
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.47 no.4
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    • pp.160-167
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    • 2015
  • The reduction of energy consumption in papermaking process has been considered as one of the major issue in the paper technology. The energy efficiency of paper mill becomes more significant for the mill which manufacture the board grade products such as linerboard with recycled paper such as OCC. The application of lignocellulose spacer to the board grade paper stock would be the feasible solution by increasing the paper bulk and the drying efficiency. The major defects originated from the application of the lignocellulose spacer could be the loss of strength properties. In this study, the ways for improving the strength properties of the spacer-added linerboard were suggested and evaluated. The effects of the addition of various types polyelectrolytes were tested and the different methods of polyelectrolytes were applied for finding the efficient way. The pretreatments of lignocellulose spacer with the polyelectrolytes during wood spacer hydration resulted in the higher strength properties than the typical application method such as the addition to the mixed stock. Multilayer treatments of the spacer with polyelectrolytes were also evaluated and leaded to the higher strength properties with the similar bulk improvement.

Accelerating Numerical Analysis of Reynolds Equation Using Graphic Processing Units (그래픽처리장치를 이용한 레이놀즈 방정식의 수치 해석 가속화)

  • Myung, Hun-Joo;Kang, Ji-Hoon;Oh, Kwang-Jin
    • Tribology and Lubricants
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    • v.28 no.4
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    • pp.160-166
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    • 2012
  • This paper presents a Reynolds equation solver for hydrostatic gas bearings, implemented to run on graphics processing units (GPUs). The original analysis code for the central processing unit (CPU) was modified for the GPU by using the compute unified device architecture (CUDA). The red-black Gauss-Seidel (RBGS) algorithm was employed instead of the original Gauss-Seidel algorithm for the iterative pressure solver, because the latter has data dependency between neighboring nodes. The implemented GPU program was tested on the nVidia GTX580 system and compared to the original CPU program on the AMD Llano system. In the iterative pressure calculation, the implemented GPU program showed 20-100 times faster performance than the original CPU codes. Comparison of the wall-clock times including all of pre/post processing codes showed that the GPU codes still delivered 4-12 times faster performance than the CPU code for our target problem.

A Study on the Apparel Sizing System of ISO for Chinese Adult Women (중국 성인여성(中國 成人女性)의 ISO에 따른 의류치수규격 연구(衣類値數規格 硏究))

  • Sohn, Hee-Soon;Wee, Hye-Jung;Kim, Eun-Hee;Kang, Yeon-Kyung
    • Journal of Fashion Business
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    • v.10 no.1
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    • pp.58-78
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    • 2006
  • This study materializes body type measurement based on ISO(International Standard Organization)size system, targeting 1381 Chinese women, and suggests clothes size standards. It provides basic information on Chinese women size for Korean clothes companies advanced in China to strengthen the national competitiveness of Korean clothing industry. First, after the body type examination, based on the ISO's drop value, the results of types are in its decreasing order: A, M, H, and D. Second, women upper garment sizes by body types are set in the section of height 152cm, 160cm, and 168cm. Garment sizes are suggested based on the section that has more than 0.8% of appearance rate for the survey target: A, H, and M. Third, the clothes sizes of women pants are set in the section of height 152cm, 160cm, and 168cm just with the same as the upper garment.

Efficient Strategy to Identify Gene-Gene Interactions and Its Application to Type 2 Diabetes

  • Li, Donghe;Wo, Sungho
    • Genomics & Informatics
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    • v.14 no.4
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    • pp.160-165
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    • 2016
  • Over the past decade, the detection of gene-gene interactions has become more and more popular in the field of genome-wide association studies (GWASs). The goal of the GWAS is to identify genetic susceptibility to complex diseases by assaying and analyzing hundreds of thousands of single-nucleotide polymorphisms. However, such tests are computationally demanding and methodologically challenging. Recently, a simple but powerful method, named "BOolean Operation-based Screening and Testing" (BOOST), was proposed for genome-wide gene-gene interaction analyses. BOOST was designed with a Boolean representation of genotype data and is approximately equivalent to the log-linear model. It is extremely fast, and genome-wide gene-gene interaction analyses can be completed within a few hours. However, BOOST can not adjust for covariate effects, and its type-1 error control is not correct. Thus, we considered two-step approaches for gene-gene interaction analyses. First, we selected gene-gene interactions with BOOST and applied logistic regression with covariate adjustments to select gene-gene interactions. We applied the two-step approach to type 2 diabetes (T2D) in the Korea Association Resource (KARE) cohort and identified some promising pairs of single-nucleotide polymorphisms associated with T2D.

Wide Dynamic Range CMOS Image Sensor with Adjustable Sensitivity Using Cascode MOSFET and Inverter

  • Seong, Donghyun;Choi, Byoung-Soo;Kim, Sang-Hwan;Lee, Jimin;Shin, Jang-Kyoo
    • Journal of Sensor Science and Technology
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    • v.27 no.3
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    • pp.160-164
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    • 2018
  • In this paper, a wide dynamic range complementary metal-oxide-semiconductor (CMOS) image sensor with the adjustable sensitivity by using cascode metal-oxide-semiconductor field-effect transistor (MOSFET) and inverter is proposed. The characteristics of the CMOS image sensor were analyzed through experimental results. The proposed active pixel sensor consists of eight transistors operated under various light intensity conditions. The cascode MOSFET is operated as the constant current source. The current generated from the cascode MOSFET varies with the light intensity. The proposed CMOS image sensor has wide dynamic range under the high illumination owing to logarithmic response to the light intensity. In the proposed active pixel sensor, a CMOS inverter is added. The role of the CMOS inverter is to determine either the conventional mode or the wide dynamic range mode. The cascode MOSFET let the current flow the current if the CMOS inverter is turned on. The number of pixels is $140(H){\times}180(V)$ and the CMOS image sensor architecture is composed of a pixel array, multiplexer (MUX), shift registers, and biasing circuits. The sensor was fabricated using $0.35{\mu}m$ 2-poly 4-metal CMOS standard process.

Quantization and Calibration of Color Information From Machine Vision System for Beef Color Grading (소고기 육색 등급 자동 판정을 위한 기계시각 시스템의 칼라 보정 및 정량화)

  • Kim, Jung-Hee;Choi, Sun;Han, Na-Young;Ko, Myung-Jin;Cho, Sung-Ho;Hwang, Heon
    • Journal of Biosystems Engineering
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    • v.32 no.3
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    • pp.160-165
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    • 2007
  • This study was conducted to evaluate beef using a color machine vision system. The machine vision system has an advantage to measure larger area than a colorimeter and also could measure other quality factors like distribution of fats. However, the machine vision measurement is affected by system components. To measure the beef color with the machine vision system, the effect of color balancing control was tested and calibration model was developed. Neural network for color calibration which learned reference color patches showed a high correlation with colorimeter in L*a*b* coordinates and had an adaptability at various measurement environments. The trained network showed a very high correlation with the colorimeter when measuring beef color.

Process Development for Automotive Hybrid Hood using Magnesium Alloy AZ31B Sheet (마그네슘 합금 AZ31B 판재를 이용한 자동차 하이브리드 후드 개발 프로세스)

  • Jang, D.H.
    • Transactions of Materials Processing
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    • v.20 no.2
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    • pp.160-166
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    • 2011
  • Weight reduction while maintaining functional requirements is one of the major goals in the automotive industry. The use of lightweight magnesium alloys offers great potential for reducing weight because of the low density of these alloys. However, the formability and the surface quality of the final magnesium alloy product for auto-body structures are not acceptable without a careful optimization of the design parameters. In order to overcome some of the main formability limitations in the stamping of magnesium alloys, a new approach, the so-called "hybrid technology", has been recently proposed for body-in-white structural components. Within this approach, necessary level of mechanical joining can be obtained through the use of lightweight material-steel adhesion promoters. This paper presents the development process of an automotive hybrid hood assembly using magnesium alloy sheets. In the first set of material pairs, the selected materials are magnesium alloy AZ31B alloy and steel(SGCEN) as inner and outer panels, respectively. In order to optimize the design of the inner panel, the stamping process was analyzed with the finite element method (FEM). Laser welding by CW Nd:YAG were used to join the magnesium alloy sheets. Based on the simulation results and mechanical test results of the joints, the determination of die design variables and their influence on formability were discussed. Furthermore, a prototype based on the proposed design was manufactured and the static stiffness test was carried out. The results demonstrate the feasibility of the proposed hybrid hood with a weight reduction of 25.7%.

Enhancement of the Speed Response of PMSM Sensorless Control Using A New Adaptive Sliding Mode Observer (새로운 적응 슬라이딩 모드 관측기를 이용한 PMSM 센서리스 속도 응답특성 향상)

  • Kim, Hong-Ryel;Son, Ju-Beom;Lee, Jang-Myung
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.1
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    • pp.160-167
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    • 2010
  • This paper proposes an adaptive sliding mode observer (SMO), which adds the estimation function of the stator resistance to a new sliding mode observer for the robust sensorless control of permanent magnet synchronous motor (PMSM) with variable parameters. To reduce the chattering problem commonly found in the conventional sliding mode observer where the low-pass filter and additional position compensation of the rotor are used, the sigmoid function is used for the control of a switching function in this research. With the estimation of the stator resistance, the proposed observer can improve the control performance by reducing the estimation error of the motor's speed. Note that the stator resistance is varying with the ambient temperature and becomes an error source for the sensorless control of PMSM. The new sliding mode observer has better efficiency than the conventional adaptive sliding mode observer by reducing the time consuming integral calculations. The stability of the proposed adaptive sliding mode observer is verified by the Lyapunov function in determining the observer gains, and the effectiveness of the observer is demonstrated by simulations and experiments.

The Hydrogen Production from the Hydrolysis of Mg-Graphite Pellet for Military Fuel Cells (군용 연료전지 적용을 위한 Mg-Graphite 펠렛의 가수분해 반응을 이용한 수소생산)

  • Park, Minsun;Yu, Minkyu;Kim, Jongsoo;Kwon, Hyuksang
    • Journal of the Korea Institute of Military Science and Technology
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    • v.18 no.2
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    • pp.160-166
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    • 2015
  • On board hydrogen generation from the hydrolysis of an active metal is very attractive due to its economical, convenient, and safe reasons. A Mg-graphite pellet has been designed as a hydrogen source for portable fuel cell. Mg (1 g) + 0.10 g graphite pellet showed an excellent hydrogen generation rate that is equivalent to 15.8 ml/g.min from its hydrolysis. The hydrogen generation rate of the pellet is significantly increased due to the galvanic corrosion by galvanic cells between Mg anode and graphite cathode in a 10.wt. % NaCl solution at a room temperature.