• Journal of Biomedical Engineering Research
• /
• v.35 no.4
• /
• pp.99-104
• /
• 2014

Generally, human eye blinks are closely associated with the cognitive state or visual attention such as attentional requirements on visual stimuli. These previous studies have reported that eye blinks are related to explicit visual attention using blink rate, pattern and blink timing across subjects. However, these results have been obtained in a well-controlled experimental settings. So, it would prove difficult to investigate human's natural response in a continuous and realistic situation. In our study, we measured the eye blink intervals while participants viewed a movie clip. And we analyzed the blink interval data for relationship between visual attention and eye blink intervals. 24 participants took part in two experimental sessions, first session to measure the IEBI while viewing the movie clip and second session to conduct a memory performance test using a self-questionnaire, which were spaced 3 weeks apart. The results indicate significantly higher memory performance at long IEBI period than short IEBI period while watching a movie clip(t = 3.257, df = 17, p < 0.005, 2-tailed). In addition, memory performance score significantly correlated with the IEBI value(spearman's rho = 0.40, N = 36, p < 0.01, 2-tailed). Our results suggest that IEBI is used to measure or assess visual attention while wiewing the movie that it is capable of simulating aspects of real-life experiences by visual attention. Thus, we expect IEBI to be used to measure or assess our visual attention, cognition, further emotion about not only movies, advertisements and other cultural contents but also cognitive science.

• Journal of Adhesion and Interface
• /
• v.13 no.2
• /
• pp.73-84
• /
• 2012

The transfer mechanism of optical information at the interface of air and glass (the air-glass IF) has been investigated by thoroughly fulfilling the theoretical and experimental analyses regarding the FTIR (Frustrated Total Internal Reflection) and moisture effects on the fingerprint onto a glass cup with water. As for the fingerprint onto a glass cup with water its image was observed to be very vivid, which turned out to be due to the difference between the two light intensities reflected on the air-glass IF and the wet fingerprint ridge by manipulating the optical theories such as Fresnel relation, Snell's law, FTIR, GT (general transmission) and so on. In addition, the experimental inspection for FTIR and moisture effects on the fingerprint image also evidenced the fact that the vivid fingerprint image originated from the moisture effect rather than the FTIR phenomenon.

• Korean Journal of Materials Research
• /
• v.29 no.4
• /
• pp.271-276
• /
• 2019

Oxide-dispersion-strengthened (ODS) alloy has been developed to increase the mechanical strength of metallic materials; such an improvement can be realized by distributing fine oxide particles within the material matrix. In this study, the ODS layer was formed in the surface region of Zr-based alloy tubes by laser beam treatment. Two kinds of Zr-based alloys with different alloying elements and microstructures were used: KNF-M (recrystallized) and HANA-6 (partial recrystallized). To form the ODS layer, $Y_2O_3$-coated tubes were scanned by a laser beam, which induced penetration of $Y_2O_3$ particles into the substrates. The thickness of the ODS layer varied from 20 to $55{\mu}m$ depending on the laser beam conditions. A heat affected zone developed below the ODS layer; its thickness was larger in the KNF-M alloy than in the HANA-6 alloy. The ring tensile strengths of the KNF-M and HANA-6 alloy samples increased more than two times and 20-50%, respectively. This procedure was effective to increase the strength while maintaining the ductility in the case of the HANA-6 alloy samples; however, an abrupt brittle facture was observed in the KNF-M alloy samples. It is considered that the initial microstructure of the materials affects the formation of ODS and the mechanical behavior.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.14 no.5
• /
• pp.871-879
• /
• 2011

The internal deck structure of turtle ship has been investigated with the following approach manner. Firstly the 5 species of turtle ship are identified by examining the characteristics of 5 turtle ships revealed by the librarian or paintings. Secondly the centers of gravity and buoyancy for each type are calculated to evaluate the turtle ship's buoyancy stability. Thirdly the optimal deck structures for 5 turtle ships are additionally assessed from the viewpoint of the interoperability of soldier's missions to get more meaningful conclusion. From the results obtained by the well refined analyses above, one can identify that Changjeguyseon and Lee Chung Mu Gong descendent family's turtle ship possess one layer deck, and the tongjeyoung and jwasuyoung turtle ship consist of 1 and half story deck, and the one disclosed by Yoon has 2 story structure.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.9
• /
• pp.1629-1635
• /
• 2016

A novel bacteriophage, PBES 02, infecting Cronobacter sakazakii was isolated and characterized. It has a spherical head of 90 nm in diameter and a tail of 130 nm in length, and belongs to Myoviridae as observed under a transmission electron microscope. The major virion protein appears to be 38 kilodaltons (kDa) in size. The latent period of PBES 02 is 30 min and the burst size is 250. Infectivity of the phage remained intact after exposure to temperatures ranging from 4℃ to 55℃ for 1 h. It was also stable after exposure to pHs ranging from 6 to 10 for 1 h. The phage effectively removed contaminating Cronobacter sakazakii from broth infant formula. PBES 02 has a double-stranded DNA genome of 149,732 bases. Its GC ratio is 50.7%. Sequence analysis revealed that PBES 02 has 299 open reading frames (ORFs) and 14 tRNA genes. Thirty-nine ORFs were annotated, including 24 related to replication and regulation functions, 10 related to structural proteins, and 5 related to DNA packaging. The genome of PBES 02 is closely related to that of two other C. sakazakii phages, CR3 and CR8. Comparison of DNA sequences of genes encoding the major capsid protein revealed a wide geographical distribution of related phages over Asia, Europe, and America.

• Nuclear Engineering and Technology
• /
• v.42 no.2
• /
• pp.193-202
• /
• 2010

In order to study the cladding properties of zirconium after a loss-of-coolant accident (LOCA)-simulation oxidation and water quenching test, commercial Zircaloy-4 and two kinds of HANA claddings were oxidized at temperatures ranging from $900^{\circ}C$ to $1250^{\circ}C$ and exposed for 300 s, and then cooled to $700^{\circ}C$ before quenching. Microstructural observations were made to evaluate the matrix characteristics with the chemical compositions after the LOCA-simulation test. Ring compression testing was then performed to compare the ductile behaviour of the HANA and Zircaloy-4 claddings. An X-ray diffraction (XRD) analysis was carried out for temperatures ranging from room temperature to $1250^{\circ}C$ for the oxide layer to verify the oxide crystal structure at each oxidation temperature.

• Journal of the Korean Society for Heat Treatment
• /
• v.18 no.3
• /
• pp.164-171
• /
• 2005

Iodine-Induced Stress Corrosion Cracking (ISCC) properties of Zircaloy-4 and HANA4 developed in KAERI for the high burn-up nuclear fuel cladding were evaluated. To confirm the effect of final heat treatment on ISCC resistance of Zr-alloy, stress relieved and recrystallized specimens were prepared and tested. With the pre-cracked specimen at internal surface, ISCC crack propagation rates and threshold stress intensity factor ($K_{ISCC}$) based on the fracture mechanics were measured by internal pressurization test at $350^{\circ}C$ in iodine environment. $K_{ISCC}$ of Zircaloy-4 and HANA4 cladding were $3.3MPa{\cdot}m^{1/2}$ and $4.4MPa{\cdot}m^{1/2}$, respectively. Pitting corrosion at the crack surface was observed and it seemed that TG crack propagation was derived from the pitting.

• Proceedings of the Korean Nuclear Society Conference
• /
• 2005.05a
• /
• pp.423-424
• /
• 2005

The performance of HANA claddings was evaluated in out-of-pile conditions. All the performance test results revealed that HANA claddings were superior to the reference claddings such as Zircaloy-4 and A-cladding. Corrosion resistance was improved by 60 to 70% compared to the commercial claddings. Creep, burst, tensile, LOCA, wear and microstructural properties were shown to be as good as the commercial claddings.

• Korean Journal of Materials Research
• /
• v.29 no.8
• /
• pp.483-490
• /
• 2019

Currently, the Korean nuclear industry uses ZIRLO as material for nuclear fuel cladding(zirconium alloy). KEPCO Nuclear Fuel is in the process of developing a HANA alloy to enable domestic production of cladding. Cladding manufacture involves multistage heat treatments and pickling processes, the latter of which is vital for the removal of defects and impurities on the cladding surface. SMUT that forms on the cladding surface during such pickling process is a source of surface defects during heat treatment and post-treatment processes if not removed. This study analyzes ZIRLO, HANA-4, and HANA-6 alloy claddings to extensively study the SEM/EDS, XRD, and particle size characteristics of SMUT, which are second phase particles that are formed on the cladding surface during pickling processes. Using the analysis results, this study observes SMUT formation characteristics according to Nb concentration in Zr alloys during the washing process following the pickling process. In addition, this study observes SMUT removal characteristics on cladding surfaces according to concentrations of nitric acid and hydrofluoric acid in the acid solution.

• Journal of Pharmaceutical Investigation
• /
• v.41 no.2
• /
• pp.117-123
• /
• 2011

Loxoprofen sodium, a 2-phenylpropionate non-steroidal anti-inflammatory drug (NSAID), has marked analgesic and antipyretic activities and relatively weak gastrointestinal ulcerogenicity. The purpose of the present study was to evaluate the bioequivalence of two loxoprofen sodium tablets, Hana loxoprofen sodium tablet (Hana Pharm. Co., Ltd.) and Dongwha Loxonin$^{(R)}$ tablet (Dongwha Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The in vitro release of loxoprofen from the two loxoprofen sodium formulations was tested using KP IX Apparatus II method with various dissolution media. Twenty four healthy Korean male volunteers, $22.83{\pm}1.862$ years in age and $69.92{\pm}9.14$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ crossover study was employed. After a single tablet containing 60 mg as loxoprofen sodium was orally administered, blood samples were taken at predetermined time intervals and the concentrations of loxoprofen in serum were determined using a online column-switching HPLC method with UV/Vis detection. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC^t$, $C_{max}$ and $T_{max}$ were calculated, and computer programs (Equiv Test and K-BE Test 2002) were utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and un-transformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, Dongwha Loxonin$^{(R)}$ tablet, were 2.03, 2.99 and -9.49% for $AUC_t$, $C_{max}$, and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log0.8 to log1.25 (e.g., log0.9831~log1.0535 and log0.9455~log1.1386 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Hana loxoprofen sodium tablet was bioequivalent to Dongwha Loxonin$^{(R)}$ tablet.