• Title/Summary/Keyword: HAM-D

Search Result 509, Processing Time 0.027 seconds

Correlation between Instrument on Pattern Identification for Depression and Psychological Tests by Statistical Analysis (통계적 분석을 통한 우울증 변증도구와 심리검사의 상관성 연구)

  • Kim, Hwan;Lee, Hun-Soo;Lee, Eun Jung;Park, Joon-Ho;Kang, Wee-Chang;Jung, In Chul
    • Journal of Oriental Neuropsychiatry
    • /
    • v.27 no.3
    • /
    • pp.131-146
    • /
    • 2016
  • Objectives: This study was performed to determine the correlation between Instrument on Pattern Identification for Depression and Psychological tests by Pearson Correlation Coefficient and Regression analysis.Methods: Two assessors carried out the evaluation using the instrument on pattern identification for depression. They also performed the following psychological tests: Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State-Trait Anger Expression Inventory (STAXI), the Temperament and Character Inventory (TCI), Insomnia Severity Index (ISI_Total), Self-disclosure Inventory, subjective well-being Inventory, Health perception Inventory, and Personality Assessment Inventory (PAI). A total of 167 participants who got HAM-D score over 12 were targeted for the evaluation. Our research team carried out Pearson correlation coefficient analyses and regression analysis between pattern identification for depression and Psychological tests. We listed the results by descending order and interpreted the results.Results: Pearson correlation analysis revealed the following results: 1) Stagnation of Liver Gi was associated with BDI (0.60) and STAI (0.55); 2) Dual Deficiency of the Heart and Spleen was associated with BDI (0.60), ISI_Total (0.52), and STAI (0.42); 3) Relieving stagnation of Phlegm-Gi was associated with BDI (0.65), STAI (0.54), and Subjective well-being inventory (−0.52); 4) Gi-deficiency Mingled with sputum was associated with BDI (0.50), ISI_Total (0.40), and STAI (0.395); 5) Stagnant Gi transforming into fire was associated with BDI (0.56), STAI_TR (0.51), and Health perception Inventory (−0.458); 6) Yin-Deficiency with Effulgent Fire was associated with BDI (0.55), ISI_total (0.54), and STAI (0.41).Conclusions: Through correlation analysis between Instrument on Pattern Identification for Depression and Psychological tests, we could suggest a System for Oriental Medical Diagnosis for Depression.

Antimutagenic and Cytotoxic Effects of an Ethanol Extract of Buckwheat Sprout (메밀싹 에탄올 추출물의 항돌연변이원성 및 암세포 성장억제 효과)

  • Cui, Cheng-Bi;Lee, Eui-Yong;Ham, Seung-Shi;Lee, Deuk-Sik
    • Applied Biological Chemistry
    • /
    • v.51 no.3
    • /
    • pp.212-218
    • /
    • 2008
  • This study was performed to determine the antimutagenic and anticancer effects of ethanol extract of buckwheat sprout using Ames test and SRB assay, respectively. An ethyl acetate fraction (200 ${\mu}/plate$) from the ethanol extract of buckwheat sprout showed inhibition rate of 80.6% against the mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Salmonella typhimurium TA100 strain. Also the ethyl acetate fraction (200 ${\mu}/plate$) showed higher antimutagenic activity than other fractions against the mutagenesis induced by 4-nitroquinoline-1-oxide (4NQO) in Salmonella typhimurium TA98 and TA100. In addition, the ethyl acetate fraction (200 ${\mu}/plate$) showed high antimutagenic effect of 80.9% and 85.9% against the mutation of TA98 and TA100 strains induced by 3-amino-1,4-dimethyl-5H-pyrido-(4,3-b)indol (Trp-P-1), respectively. The cytotoxic effects of each solvent fraction from the ethanol extract of buckwheat sprout against human cancer cell lines including lung carcinoma (A549), gastric carcinoma (AGS), breast adenocarcinoma (MCF-7), hepatocellular carcinoma (Hep3B), and colon adenocarcinoma (Colo 205) were investigated. The ethyl acetate fraction of buckwheat sprout ethanol extract at the concentration of 1.0 mg/ml showed strong cytotoxic activities of 70.3, 94.8, 79.6, 82.3, and 73.2% against A549, AGS, MCF-7, Hep3B and Colo 205 cancer cell lines, respectively.

Development of a Risk Management Information System(RMIS) for the LPG refueling station by utilizing GIS (지리정보시스템(GIS)을 이용한 LPG 충전소 위험관리정보시스템 개발에 관한 연구)

  • Ham, Eun-Gu;Roh, Sam-Kew
    • 한국가스학회:학술대회논문집
    • /
    • 2007.04a
    • /
    • pp.195-200
    • /
    • 2007
  • 본 연구는 도심지에 위치한 LPG 충전소를 연구범위로 하여 공간정보의 활용이 가장 많이 요구되는 안전관리 분야의 업무를 중심으로 공간정보를 효율적으로 구축 활용하기 위하여 데이터베이스를 중심으로 위험관리정보 시스템을 개발하였다. 이를 바탕으로 정량적 위험성 평가의 자동화를 통해 나타난 위험성을 실시간에 제어하기 위한 필요조건을 표준화하여 기초 정보자료로 구축, 이를 지리정보기능과 연동하여 LPG 충전소의 안전검사의 효율화, 사전 위험성 평가, 사고대응 판단의 효과적인 의사결정을 유도 할 수 있는 기반을 제공한다. 위험관리정보시스템(RMIS, Risk Management Information System) 개발절차는 다음과 같다 첫째, 도심지에 위치한 LPG 충전소 위험성 평가를 수행함에 있어서 기본적인 데이터인 부지내(On-site) 관련 자료와 부지 외(Off-site) 관련 자료를 관계형 데이터베이스(RDB, Relational Database)로 개발하였다. 둘째, Visual Basic을 이용하여 사용자가 효과적으로 위험을 관리 제어 할 수 있는 위험관리 통합 데이터베이스 시스템 개발하였다. 셋째, 위험관리 통합 데이터베이스 시스템과 지리정보시스템에 연동을 통한 의사결정 방안 제시하였다. 위험관리정보시스템(RMIS) 프로그램을 개발을 통하여 다음과 같은 결과를 도출하였다. 첫째, 위험관리 데이터 이용하여 사용자와 검사자가 효과적으로 위험을 사전관리 할 수 있는 공유정보를 구축하였다. 둘째, 위험 관리를 부지 내와 부지 외로 나누어 관리함으로서 시설 내부 뿐 만 아니라 시설외부에 미치는 영향을 모두 고려하여 구축하므로 서, 중대사고에 대응 할 수 있는 종합적인 안전관리 기반을 조성하였다. 셋째, 사용자 인터페이스를 바탕으로 비상사태 발생시에 신속하고 정확한 의사결정을 할 수 있는 기반을 조성하였다. 제공하여 응용GIS 구축의 생산성 및 품질 향상에 기여할 뿐만 아니라 우리의 최종목표인 GIS 소프트웨어 자동 생산에도 크게 기여할 것으로 사료된다. 등)을 교통망상에 표시할 수 있음으로서 의사결정에 보다 많은 도움을 줄 수 있을 것이다. 비트율의 증가와 화질 열화는 각각 최대 1.32%와 최대 0.11dB로 무시할 수 있을 정도로 작음을 확인 하였다.을 알 수 있었다. 현지관측에 비해 막대한 비용과 시간을 절약할 수 있는 위성영상해석방법을 이용한 방법은 해양수질파악이 가능할 것으로 판단되며, GIS를 이용하여 다양하고 복잡한 자료를 데이터베이스화함으로써 가시화하고, 이를 기초로 공간분석을 실시함으로써 환경요소별 공간분포에 대한 파악을 통해 수치모형실험을 이용한 각종 환경영향의 평가 및 예측을 위한 기초자료로 이용이 가능할 것으로 사료된다.염총량관리 기본계획 시 구축된 모형 매개변수를 바탕으로 분석을 수행하였다. 일차오차분석을 이용하여 수리매개변수와 수질매개변수의 수질항목별 상대적 기여도를 파악해 본 결과, 수리매개변수는 DO, BOD, 유기질소, 유기인 모든 항목에 일정 정도의 상대적 기여도를 가지고 있는 것을 알 수 있었다. 이로부터 수질 모형의 적용 시 수리 매개변수 또한 수질 매개변수의 추정 시와 같이 보다 세심한 주의를 기울여 추정할 필요가 있을 것으로 판단된다.변화와 기흉 발생과의 인과관계를 확인하고 좀 더 구체화하기 위한 연구가 필요할 것이다.게 이루어질 수 있을 것으로 기대된다.는 초과수익률이 상승하지만, 이후로는 감소하므로, 반전거래전략을 활용하는 경우 주식투자기간은 24개월이하의 중단기가 적합함을 발견하였다. 이상의 행태적 측면과 투자성과측면의 실증결과를 통하여 한국주식시장에 있어서 시장수익률을 평균적으로 초과할 수 있는 거래전략은 존재하므로 이러한 전략을 개발 및 활용할 수 있으며, 특히, 한국주

  • PDF

Comparison of Effects of Different Activation Treatments on Development of Rabbit Embryos Reconstituted with Fetal Fibroblast

  • Lee, H.J.;Yoo, J.G.;Cho, S.R.;Lee, S.L.;Chong, J.R.;Yeo, H.J.;Hwang, J.M.;Park, J.S.;Yea, E.H.;Rho, G.J.;Choe, S.Y.
    • Proceedings of the KSAR Conference
    • /
    • 2001.03a
    • /
    • pp.22-22
    • /
    • 2001
  • To produce reconstituted rabbit embryos with fetal fibroblasts, the present study was evaluated the efficiencies of the different fusion and activation conditions as assessments of subsequent development and chromosome in the embryos. New Zealand White rabbits were used throughout the study. Fetal fibroblasts collected from 22-d of fetuses were cultured in DMEM + 10% FBS in 5% $CO_2$ in air. The culture was maintained for 10 passages. In every passage half of cell suspension were kept In frozen. From rabbits treated with FSH in 30% PVP solution and hCG, oocytes were surgically collected from oviducts at 14 h post-hCG injection and stripped off their cumulus cells by re-pipetting in a 300 IU hyaluronidase solution. Oocytes with an extruded first polar body and dense cytoplasm were enucleated by micromanipulation in Ham's F-10 medium+7.5 g/$m\ell$ cytochalasin B. Euncleation was confirmed under a fluorescence microscope after staining with 5 g/$m\ell$ bisbenzimide for 2 min. Each enucleated oocyte was injected with a fetal fibroblast into a perivitelline space. Reconstructed eggs were compared fusion rates either at 2.0 ㎸/cm or 1.6 ㎸/cm(60 sec, double pulses). After fusion, all eggs were activated with the combination of 5 M ionomycin (5 min) and 10 g/$m\ell$ cycloheximide (CHX, 3h), and cultured in CRlaa medium and transferred into TCM199+10% FBS on day 3. Although there was not significantly differ in fusion rate between treatments (60%, 2.0 ㎸/cm vs. 79.4%, 1.6 ㎸/cm), none of them in the eggs fused with 2.0 ㎸/cm developed to blastocyst. In comparison of development and chromosome status between different activation treatments (Group 1; 5 M ionomycin/10 g/$m\ell$ CHX, Group 2; 5 M ionomycin/5 g/$m\ell$ CHX + 2 mM DMAP after fusion with 1.6 ㎸/cm), there were not differ in cleavage and development rates (67.3% and 28.9% in Group 1; 67% and 33% in Group 2). All out of 8 embryos evaluated in Group 1 appeared a normal diploid chromosome sets and mean number of cells (Mean SEM) on day 4.5 of culture was 141.5 23.15 (n=8). It can be concluded that the use of cycloheximide has not happened in chromosome abnormalities, and fetal fibroblasts can be used for cloning in rabbit.

  • PDF

A preliminary study of Oxalis corniculata L. as a new banker plant: Control efficacy against Panonychus citri (McGregor) and feeding ability of two natural enemies on Tetranychina harti (Ewing) (천적유지식물로써 괭이밥에 대한 기초연구: 괭이밥의 귤응애 밀도억제효과와 천적 2종의 괭이밥응애 포식력)

  • Oh, Chang Hak;Jin, Hye Young;Ahn, Tai Hyeon;Song, Yu Jin;Jun, Hye Jeong;Lee, Jun Seok;Ham, Eun Hye
    • Korean journal of applied entomology
    • /
    • v.56 no.3
    • /
    • pp.267-273
    • /
    • 2017
  • To protect plants from damage caused by Panonychus citri (McGregor), practical methods for the use banker plants have been developed to provide a habitat and augment natural enemies of several agricultural pests. The average population density of predatory mites on an Oxalis corniculata (creeping sorrel) sod culture was significantly higher (three times) than that on normal sod culture. Furthemore, the average population density of spider mites on creeping sorrel sod culture was significantly lower (3.7 times) than when weed control was practiced. Average consumption of the eggs and females of Tetranychina harti (Ewing) by Neoseiulus californicus (McGregor) females was approximately 1.96 eggs and 1.93 females per day, respectively. Phytoseiulus persimilis AthiasHenriot females never consumed T. harti. However, total development time of T. harti from egg to adult on O. corniculata was 17.4 days, and hatchability and survival rate were 77.5% and 84.8%, respectively.

Development of the Reference Korean Female Voxel Phantom (한국인 기준여성 체적소형 모의체 개발)

  • Ham, Bo-Kyoung;Cho, Kun-Woo;Yeom, Yoen-Soo;Jeong, Jong-Hwi;Kim, Chan-Hyeong;Han, Min-Cheol
    • Journal of Radiation Protection and Research
    • /
    • v.37 no.1
    • /
    • pp.41-49
    • /
    • 2012
  • The objective of this study is for development of the reference Korean female phantom, HDRK-Woman. The phantom was constructed by adjusting a Korean woman voxel phantom to the Reference Korean data. The Korean woman phantom had been developed based on the high-resolution color slice images obtained from an adult Korean female cadaver. There were a total of 39 organs including the 27 organs specified in ICRP 103 for effective dose calculation. The voxel resolution of the phantom was $1.976{\times}1.976{\times}2.0619\;mm^3$ and the voxel array size is $261{\times}109{\times}825$ in the x, y and z directions. Then, the voxel resolution was changed to $2.0351{\times}2.0351{\times}2.0747\;mm^3$ for adjustment of the height and total bone mass of the phantom to the Reference Korean data. Finally, the internal organs and tissue were adjusted using in-house software program developed for 3D volume adjustment of the organs and tissue. The effective dose values of HDRK phantoms were calculated for broad parallel photon beams using MCNPX Monte Carlo code and compared with those of ICRP phantoms.

Magnetoresistance of Bi Nanowires Grown by On-Film Formation of Nanowires for In-situ Self-assembled Interconnection

  • Ham, Jin-Hee;Kang, Joo-Hoon;Noh, Jin-Seo;Lee, Woo-Young
    • Proceedings of the Korean Magnestics Society Conference
    • /
    • 2010.06a
    • /
    • pp.79-79
    • /
    • 2010
  • Semimetallic bismuth (Bi) has been extensively investigated over the last decade since it exhibits very intriguing transport properties due to their highly anisotropic Fermi surface, low carrier concentration, long carrier mean free path l, and small effective carrier mass $m^*$. In particular, the great interest in Bi nanowires lies in the development of nanowire fabrication methods and the opportunity for exploring novel low-dimensional phenomena as well as practical application such as thermoelectricity[1]. In this work, we introduce a self-assembled interconnection of nanostructures produced by an on-film formation of nanowires (OFF-ON) method in order to form a highly ohmic Bi nanobridge. A Bi thin film was first deposited on a thermally oxidized Si (100) substrate at a rate of $40\;{\AA}/s$ by radio frequency (RF) sputtering at 300 K. The sputter system was kept in an ultra high vacuum (UHV) of $10^{-6}$ Torr before deposition, and sputtering was performed under an Ar gas pressure of 2m Torr for 180s. For the lateral growth of Bi nanowires, we sputtered a thin Cr (or $SiO_2$) layer on top of the Bi film. The Bi thin films were subsequently put into a custom-made vacuum furnace for thermal annealing to grow Bi nanowires by the OFF-ON method. After thermal annealing, the Bi nanowires cannot be pushed out from the topside of the Bi films due to the Cr (or $SiO_2$) layer. Instead, Bi nanowires grow laterally as a mean s of releasing the compressive stress. We fabricated a self-assembled Bi nanobridge (d=192 nm) device in-situ using OFF-ON through annealing at $250^{\circ}C$ for 10hours. From I-V measurements taken on the Bi nanobridge device, contacts to the nanobridge were found highly ohmic. The quality of the Bi nanobridge was also proved by the high MR of 123% obtained from transverse MR measurements. These results manifest the possibility of self-assembled nanowire interconnection between various nanostructures for a variety of applications and provide a simple device fabrication method to investigate transport properties on nanowires without complex patterning and etching processes.

  • PDF

Effects of Maturity at Harvest and Wilting Days on Quality of Round Baled Rye Silage

  • Kim, J.G.;Chung, E.S.;Seo, S.;Ham, J.S.;Kang, W.S.;Kim, D.A.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.14 no.9
    • /
    • pp.1233-1237
    • /
    • 2001
  • A study was conducted to determine the effects of maturity at harvest and wilting days on the quality of round baled rye (Secale cereale L.) silage. This study was a $3{\times}3$ factorial arrangement in a split plot design with 3 replicates. The main plot was 3 harvesting dates at the stage of boot (20 Apr.), heading (29 Apr.) and flowering (14 May). The subplot was wilting day : 0 (unwilted), 0.5 and 1 day (0, 1, and 2 days at boot stage). Acid detergent fiber (ADF) and neutral detergent fiber (NDF) contents of rye silage were significantly greater than those of rye before ensiling, but crude protein (CP) content and in vitro dry matter digestibility (IVDMD) were vice versa. Buffering capacity (BC) of rye harvested at flowering stage was decreased from 264 to 202 meq/kg at 1 day wilting, however, it was increased when harvested at boot or heading stage. The pH in wilted silage was the highest while that of flowering stage was the lowest. Water soluble carbohydrate (WSC) content of wilting rye was lower than that of unwilted, and the lowest at late harvesting stage. All plots had minimal WSC content for silage fermentation. Wilting treatment and delayed harvesting date caused an increase in dry matter (DM) content of round bale silage. The content of ammonia-N expressed as a portion of total N showed negative correlation with DM content. High quality silage according to ammonia-N content could be obtained from mid-harvest with wilting. There were highly significant differences in each organic acid between harvesting dates and wilting periods. Acetic and butyric acid contents were increased with delayed harvesting and prolonged wilting period, the lactic acid content, however, was decreased. This study demonstrated that harvest of rye from heading to flowering stage with wilting would be a recommendable method for making high quality rye silage using round bale system.

Myocardial Protection by Recombinant Soluble P-selectin Glyco-protein Ligand-1: Suppression of Neutrophil and Platelet Interaction Following Ischemia and Reperfusion

  • Ham, Sang-Soo;Jang, Yoon-Young;Song, Jin-Ho;Lee, Hyang-Mi;Kim, Kwang-Joon;Hong, Jun-Sik;Shin, Yong-Kyoo
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.4 no.6
    • /
    • pp.515-523
    • /
    • 2000
  • Polymorphonuclear leukocytes (PMNs) play an important role in myocardial ischemia/reperfusion (MI/R) injury. Moreover, platelets are also important blood cells that can aggravate myocardial ischemic injury. This study was designed to test the effects of PMNs and platelets separately and together in provoking cardiac dysfunction in isolated perfused rat hearts following ischemia and reperfusion. Additional control rat hearts were perfused with $75{\times}10^6$ PMNs, with $75{\times}10^6$ platelets, or with $75{\times}10^6\;PMNs+75{\times}10^6$ platelets over a five minute perfusion followed by a 75 min observation period. No significant reduction in coronary flow (CF), left ventricular developed pressure (LVDP), or the first derivative of LVDP (dP/dt max) was observed at the end of the observation period in any non-ischemic group. Similarly, global ischemia (I) for 20 min followed by 45 minutes of reperfusion (R) produced no sustained effects on the final recovery of any of these parameters in any group of hearts perfused in the absence of blood cells. However, I/R hearts perfused with either PMNs or platelets alone exhibited decreases in these variables of $5{\sim}10%$ (p<0.05 from control). Furthermore, I/R hearts perfused with both PMNs and platelets exhibited decreases of 50 to 60% in all measurements of cardiac function (p<0.01). These dual cell perfused I/R hearts also exhibited marked increases in cardiac myeloperoxidase (MPO) activity indicating a significant PMN infiltration, and enhanced P-selectin expression on the coronary microvascular endothelium. All cardiaodynamic effects as well as PMN accumulation and P-selectin expression were markedly attenuated by a recombinant soluble PSGL-1 which inhibits selectin mediated cell adhesion. These results provide evidence that platelets and PMNs act synergistically in provoking post-reperfusion cardiac dysfunction, and that this may be largely due to cell to cell interactions mediated by P-selectin. These results also demonstrate that a recombinant soluble PSGL-1 reduces myocardial reperfusion injury by platelet and PMNs interaction.

  • PDF

A High-resolution Study of Isotopic Compositions of Precipitation (고해상도 강우동위원소변동에 대한 연구)

  • Lee, Jeonghoon;Kim, Songyi;Han, Yeongcheol;Na, Un-Sung;Oh, Yoon Seok;Kim, Young-Hee;Kim, Hyerin;Ham, Ji-Young;Choi, Hye-Bin;Koh, Dong-Chan
    • Economic and Environmental Geology
    • /
    • v.48 no.5
    • /
    • pp.371-377
    • /
    • 2015
  • Isotopic compositions of precipitation have been used to understand moisture transport in the atmosphere and interactions between precipitation and groundwater. Isotopic compositions of speleothems and ice cores, so called, ''paleoarchives'', can be utilized to interpret climate of the past and global circulation models (GCMs). The GCMs are able to explain the paleoarchives, can be validated by the precipitation isotopes. The developments of stable isotope analyzers make high-resolution isotopic studies feasible. Therefore, a high-resolution study of precipitation isotopes is needed. For this study, precipitation samples were collected for every 5 to 15 minutes, depending on precipitation rates, using an auto-sampler for precipitation isotopes near coastal area. The isotopic compositions of precipitation range from -5.7‰ (-40.1‰) to -10.8‰ (-74.3‰) for oxygen (hydrogen). The slope of ${\delta}^{18}O-{\delta}D$ diagram for the whole period is 6.8, but that of each storm is 5.1, 4.2, 7.9 and 7.7, respectively. It indicates that evaporation occurred during the first two storms, while the latter two storm did not experience any evaporation. The isotopic fractionations of precipitation has significant implications for the water cycle and high-resolution data of precipitation isotopes will be needed for the future studies.