• Title/Summary/Keyword: HAB

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Identification of a Domain in Yeast Chitin Synthase 3 Required for Biogenesis of Chitin Ring, But Not Cellular Chitin Synthesis

  • Park Hyun-Sook;Park Mee-Hyun;Kim Chi-Hwa;Woo Jeeun;Lee Jee-Yeon;Kim Sung-Uk;Choi Wonja
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2000.10a
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    • pp.39-45
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    • 2000
  • It hab been proposed that CHS3-mediated chitin synthesis during the vegitative cell cycle is regulated by CHS4. To investigate direct protein-protein interaction between their coding products, we used yeast two hybrid system and found that a domain of Chs3p was responsible for interaction with Chs4p. This domain, termed MIRC3-4 (maximum interacting region of chs3p with chs4p), spans from 647 to 700 residues. It is well conserved among CHS3 homologs of various fungi such as Candida albicans, Emericella nidulans, Neurospora crassa, Magnaporthe grisea, Ustilago maydis, Glomus versiforme, Exophiala dermatitidis, Rhizopus microsporus. A series of mutaion in the MIRC3-4 resulted in no appearance of chitin ring at the early G 1 phase but did not affect chitin synthesis in the cell wall after cytokinesis. Absence of chitin ring could be caused either by delocalization of Chs3p to the septum or by improper interaction with Chs4p. To discriminate those two, not mutually exclusive, alternatives, mutants cells were immunostained with Chs3p-specific antibody. Some exhibited localization of chs3p to the septum, while others failed. These results indicate that simultaneous localization and activation Chs3p by Chs4p is required for chitin ring synthesis.

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A Regional Approach for Integrated Coastal Management with Scientific and Local Knowledge (연안통합관리의 과학적 및 지역적 접근)

  • Lee Chan-Won
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.6 no.1
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    • pp.21-29
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    • 2003
  • Fishing, aquaculture, coastal tourism and port activities in southern coastal seas are important to the Korean economy Conventional strategies or quick-fixes may not be the best means of addressing coastal issues. Coastal issues in Korean coastal sea include harmful algal blooms (HAB), oxygen depletion, and sea grass disappearance. Regional coastal management plans have been developed during 2001~present after inauguration of Coastal Management Law in 1999. Activities such as eco-pioneer cities, pollution reduction, constitutional rearrangement, environmental regulation, monitoring indicators, and budgeting would be included in regional coastal management Planning. The successful implementation of integrated coastal management is largely dependent on the engagement of government and non-government organizations to increase the chorus of concern. The need to involve coastal area residents in restoring activities was addressed with the creation of NGOs' Association for Masan Bay Restoration (NAMR). Several restoration efforts by NAMR are currently underway in Masan Bay coastal zone with scientific and local knowledge. A new level of dialogue was achieved suggesting a sustainable picture of Masan Bay coastal area regarding to a new port construction.

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One case of SLE patient and the other case of perniotic LE patient (전신성 홍반성 루프스 환자 1례와 동창상 홍반성 루프스 환자 1례에 관한 임상적 고찰)

  • Ryeu, Hyeun-Sin;Lee, Jun-Seong;Kim, Jeong-Ho;Lee, Yong-Koo
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.15 no.2
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    • pp.244-251
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    • 2002
  • Introduction: SLE is autoimmune disease to appear systemic pathology in the connective tissue. Perniotic LE is sub-type of chronic dermal LE which causes purple macules on the terminal part of body-nose, ends of fingers, heals, calfs of the legs, elbows and knees. Objective: The purpose of this study was to estimate the efficiency of oriental medical treatment and management on the SLE and perniotic LE. Subject: We studied 2 patients who visited and hospitalized in Daejon University Oriental Hospital Dept. of Dermatology, with SLE and pemiotic LE from April 2002 till May 2002 Method: We treated them with herb medication, acupuncture and in addition to we consulted western medication if they were needed Results: In case of SLE patient, we considered it to be Yeol-Dok-Chi-Seong, so we priscriped Ga-Mi-So-Dok-Eum1, 2 , Yang-Dok-Baek-ho-Tang first. and till 22 days of hospitalization, we considered to be Gi-Eum-Yang-Heo and priscriped Ji-Hwang-Tang-Hab-Cheong-Sim-Yeon- Ja -Eum-Ga-Mi. but it wasn't adjust and high fever was reaccurred. And till 24 days of hospitalization we priscriped Gal-Geon-Hae-Gi-Tang, and becomed to 25 days, high fever was disappeared and the patient discharged and she has remained generally good condition. In case of Perniotic LE, at first we misdiagnosed her disease as a acral lentiginous melanoma, and we considered it to be Gan-Soo-Yeol-Li-Yeol- Jeung and priscriped Cheong-Pae-Sa-Gan-Tang and transferred her to another hospital, but she was diagnosed Perniotic LE Conclusion: Considering the above results, in case of SLE, in acute phase, we could treat her with oriental-western treatment, and in relief phase, we could treat her with only oriental treatment very efficiently. but in case of perniotic LE, we misdiagnosed it as a acral lentiginous melanoma, but we could experienced very rare perniotic LE case. And also further study is needed on the SLE, and perniotic LE, and we have to systematize of dyagnosis and treatment system.

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Effect of WC Particle Size on the Microstructure, Mechanical and Electrical Properties of Ag/WC Sintered Electrical Contact Material (Ag/WC 소결 전기 접점 소재의 미세조직, 기계적 및 전기적 특성에 미치는 WC 입자 크기의 영향)

  • Soobin Kim;So-Yeon Park;Jong-Bin Lim;Soon Ho Kwon;Kee-Ahn Lee
    • Journal of Powder Materials
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    • v.30 no.3
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    • pp.242-248
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    • 2023
  • The Ag/WC electrical contacts were prepared via powder metallurgy using 60 wt% Ag, 40 wt% WC, and small amounts of Co3O4 with varying WC particle sizes. After the fabrication of the contact materials, microstructure observations confirmed that WC-1 had an average grain size (AGS) of 0.27 ㎛, and WC-2 had an AGS of 0.35 ㎛. The Ag matrix in WC-1 formed fine grains, whereas a significantly larger and continuous growth of the Ag matrix was observed in WC-2. This indicates the different flow behaviors of liquid Ag during the sintering process owing to the different WC sizes. The electrical conductivities of WC-1 and WC-2 were 47.8% and 60.4%, respectively, and had a significant influence on the Ag matrix. In particular, WC-2 exhibited extremely high electrical conductivity owing to its large and continuous Ag-grain matrix. The yield strengths of WC-1 and WC-2 after compression tests were 349.9 MPa and 280.7 MPa, respectively. The high yield strength of WC-1 can be attributed to the Hall-Petch effect, whereas the low yield strength of WC-2 can be explained by the high fraction of high-angle boundaries (HAB) between the WC grains. Furthermore, the relationships between the microstructure, electrical/mechanical properties, and deformation mechanisms were evaluated.

Data-driven Model Prediction of Harmful Cyanobacterial Blooms in the Nakdong River in Response to Increased Temperatures Under Climate Change Scenarios (기후변화 시나리오의 기온상승에 따른 낙동강 남세균 발생 예측을 위한 데이터 기반 모델 시뮬레이션)

  • Gayeon Jang;Minkyoung Jo;Jayun Kim;Sangjun Kim;Himchan Park;Joonhong Park
    • Journal of Korean Society on Water Environment
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    • v.40 no.3
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    • pp.121-129
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    • 2024
  • Harmful cyanobacterial blooms (HCBs) are caused by the rapid proliferation of cyanobacteria and are believed to be exacerbated by climate change. However, the extent to which HCBs will be stimulated in the future due to increased temperature remains uncertain. This study aims to predict the future occurrence of cyanobacteria in the Nakdong River, which has the highest incidence of HCBs in South Korea, based on temperature rise scenarios. Representative Concentration Pathways (RCPs) were used as the basis for these scenarios. Data-driven model simulations were conducted, and out of the four machine learning techniques tested (multiple linear regression, support vector regressor, decision tree, and random forest), the random forest model was selected for its relatively high prediction accuracy. The random forest model was used to predict the occurrence of cyanobacteria. The results of boxplot and time-series analyses showed that under the worst-case scenario (RCP8.5 (2100)), where temperature increases significantly, cyanobacterial abundance across all study areas was greatly stimulated. The study also found that the frequencies of HCB occurrences exceeding certain thresholds (100,000 and 1,000,000 cells/mL) increased under both the best-case scenario (RCP2.6 (2050)) and worst-case scenario (RCP8.5 (2100)). These findings suggest that the frequency of HCB occurrences surpassing a certain threshold level can serve as a useful diagnostic indicator of vulnerability to temperature increases caused by climate change. Additionally, this study highlights that water bodies currently susceptible to HCBs are likely to become even more vulnerable with climate change compared to those that are currently less susceptible.

Variation in Harmful Algal Blooms in Korean coastal waters since 1970 (1970년대 이후 한국 연안의 적조 발생 변화)

  • Lim, Weol-Ae;Go, Woo-Jin;Kim, Kyoung-Yeon;Park, Jong-Woo
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.5
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    • pp.523-530
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    • 2020
  • Based on the results of harmful algal blooms (HABs) monitoring by the National Institute of Fisheries Science and local governments, the effects of changes in the marine environment on HABs are described. Since the beginning of HABs monitoring in 1972, they continued to increase from the 1980s to the 1990s. After the largest number of HAB incidents (109) in 1998; the trend declined until the 2010s. Most HABs in the 1970s were caused by diatoms. In the 1980s, coastal dinoflagellates caused HABs; Cochlodinium polykrikoides blooms have been occurring continuously since 1993. There are three HAB species that cause damage to fisheries in Korea. The high-density bloom of Karenia mikimotoi caused mass mortality in shellfish in Jinhae Bay in 1981. Karenia sp. blooms occurring around Tongyeong in 1992 killed aquaculture fish. Since the occurrence of the largest fisheries damage of KRW 76.6 billion in 1995 caused by C. polykrikoides blooms, they have been occurring continuously. The concentration of nutrients in coastal waters was the highest in the 1980s and has declined since the mid-1990s. This reduction in nutrient concentration is a good explanation for the decreasing number of HABs. Since 2016, a summer high water temperature of 30℃ or more has appeared, and the range and scale of C. polykrikoides blooms have been greatly reduced. In 2016, K. mikimotoi blooms occurred around Wando, Jangheung and Goheung and small scale blooms of C. polykrikoides occurred around Yeosu. There were no C. polykrikoides blooms in 2017; however, Alexandrium affine blooms occurred from Yeosu to Tongyeong. There was a small-scale blooms of C. polykrikoides in 2018 compared to those in the previous years. Our results show that reduction in nutrients and the high water temperature owing to climate change are a good explanation for variation in HABs in Korean coastal waters.

A Dog Park Planning Model for Promoting Animal Welfare Culture in Regional Community, Korea (지역사회의 동물복지문화 증진을 위한 도그파크 계획 모형)

  • Lim Soo-Hee;Lee Gwan-Gyu;Yang Byoung-E;Park Jong-Hwa;Sin Nam-Sik
    • Journal of the Korean Institute of Landscape Architecture
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    • v.33 no.4 s.111
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    • pp.129-142
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    • 2005
  • Korea's pet-related society has been fast growing without the base and preparations of socio-cultural animal welfare. For the most part, Korea's current public parks, in particular, have a space structure in which a lot of friction between the general public who are not fond of dogs and dog owners in public places has been happening unavoidably. A lot of countries that are taking a lead role in animal welfare have built dog parte that the general public and dogs can enjoy together. This research starts with the realization that the concept of 'dog park' needs to be introduced in Korea as more and more Koreans own dogs and other pets. This research aims to provide guidance for dog park planning by drawing a dog park planning model and to promote basics for co-existence of dogs and people in a park and set in place animal welfare early and raise the level of awareness. Total 7 types of dog put 56 planning items including dog zone, dog playground, and agility, and a selective matrix by which it is possible to select essential recommendatory optional items by each type of dog park were drawn in this research. Overall there were the highest needs in separated area for dogs in park. A dog park planning model is designed as follows. 1) To select a dog park type that was introduced. 2) To set up facilities applicable in common and planning items desired in advance by each type. 3) To zone dog park areas by the priority order of planning items that were introduced and to position necessary facilities. 4) To plan program that should be were introduced. A dog park was expected to take some positive roles such as providing opportunities to socialize dogs, activating social communities, more effective park management by participating local community members and so on.

Analysis of influence on water quality and harmful algal blooms due to weir gate control in the Nakdong River, Geum River, and Yeongsan River (낙동강, 금강 및 영산강 가동보 운영이 수질 및 녹조현상에 미치는 영향 분석)

  • Seo, Dongil;Kim, Jaeyoung;Kim, Jinsoo
    • Journal of Korea Water Resources Association
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    • v.53 no.10
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    • pp.877-887
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    • 2020
  • A 3-Dimensional hydrodynamic and water quality model was applied to evaluate the effects of weir gate operations on water quality and harmful algal bloom (HAB) occurrences at selected locations in the Nakdong River, Geum River, and Yeongsan River. For the Geum River and Yeongsan River, when the gates are left open, annual and summer Chl-a and HABs were decreased at upstream locations, Sejong Weir and Seungchon Weir, but summer average concentrations of Chl-a and HABs were increased at downstream locations, Baekje Weir and Juksan Weir. For the open scenario, the reduced hydraulic residence time in the upper stream areas of the Geum River and Yeongsan River would allow less available time for nutrient consumption that would result in higher dissolved inorganic phosphorus concentrations followed by higher algal growth in the downstream areas. However, in the case of the Nakdong River, both annual and summer Chl-a and HABs were increased in all locations for the open scenario. This condition seems to be resulted in due to increased light availability by reduced water depths. Changes in Chl-a and HABs occurrences due to the water gate control in the study sites are different due to differences in physical, chemical, and biological conditions in each location.

Estimation of Water Quality using Landsat 8 Images for Geum-river, Korea (Landsat 8 이미지영상을 이용한 영양염류농도 추정; 금강을 대상으로)

  • Lim, Jisang;Baik, Jongjin;Kim, Hyunglok;Choi, Minha
    • Journal of Korea Water Resources Association
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    • v.48 no.2
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    • pp.79-90
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    • 2015
  • In this study, the water quality parameters of Geum-river were estimated using Landsat 8 satellite image data which had launched in March 2013. The goal of this research is to predict HAB and to monitor spatial pattern of total nitrogen (TN) and total phosphorus (TP) because both TN and TP are the dominant factors of the growth of harmful algal blooms (HABs). To investigate the relationship between satellite band reflectance and in situ measurement value, Pearson' correlation coefficient analysis was used. The band2, 3, 4 and 5 reflectance values among 11 bands of Landsat 8 were used which was highly associated with detecting TN and TP. The 20 in situ data set with satellite's overpass time were identified. TN showed positive relation with band 2 (0.48), band3 (0.62), band4 (0.57) at a significance level of p<0.05. TP also showed high correlation for band2 (0.59), band3 (0.59), band4 (0.58) at a significance level of p<0.01. The optimal regression equation models were constructed for TN and TP based on multiple regression equations. The estimated concentration based on derived regression equations of TN and TP were compared with in situ measurement data. Finally, the spatial pattern of the two parameters was able be monitored through mapping on November 12, 2013 and April 21, 2014.

Figurative Analysis of Korea Tradition Metal Rice Bowl - To Choson and the Modern Age Center - (한국 전통 금속 밥그릇의 조형적 해석 -조선 및 근대를 중심으로-)

  • 윤형건
    • Archives of design research
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    • v.17 no.1
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    • pp.99-108
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    • 2004
  • Metal tableware of korea had been used from former days along with own to rice bowl exclusive use, this metal tableware has our country characteristic identity from the country that do rice to chief food to unique thing. This by recent publication we individual and peculiar ours create may. Hab, Yonyu, Omok, Okbalri of modeling of our country metal rice bowl are 4 kinds greatly. First is that is all lid in our country's metal rice bowl by 3 greatly to cultural meaning that is filled in modeling. Second, it is that there is man and woman old and the young official business while divide man and woman old and the young in our country's metal rice bowl, third, that size changes by other rice bowl according as age increases point. And item that cause definite effect in figurative feature of metal rice bowl is [ Existence and nonexistence of hoof ], [ Oral narration department's shape ], [ Reverence of oral narration belonging / Ratio of Body's height ], and [ Reverence of oral narration belonging / Ratio about Body maximum ] of it 4 be. This research finds identity of our country's design and it is basic research about that is wished to graft together in several Land of Supreme Happiness illuminating in several angles with our country characteristic metal rice bowl.

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