• 한방안이비인후피부과학회지
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• 제35권1호
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• pp.81-90
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• 2022

Objectives : The purpose of this study is to report a case of bilateral facial palsy in a patient with Guillain-Barre Syndrome after coronavirus disease 2019(COVID-19) vaccination. Methods : The patient diagnosed as Guillain-Barre Syndrome and Bilateral facial palsy after COVID-19 vaccination. We applied Korean medical treatment including acupuncture and herbal medicine for bilateral facial palsy. We used HBGS(House-Brackmann Grading System), VAS(Visual Analog Scale) to estimate the symptoms. Results : After the treatment, both facial palsy showed big improvement. Compared to the onset, HBGS improved by Grade 1/2 and VAS by 2. Conclusions : This case report shows effect of Korean medicine on Bilateral facial palsy and suggests a possibility of Korean medicine to treat adverse events following COVID-19 vaccination.

• Annals of Clinical Neurophysiology
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• 제6권2호
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• pp.92-97
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• 2004

Background: There were several studies comparing prognostic factors in Guillain-Barre syndrome treated with intravenous immunoglobulin and plasmapheresis. However, there were controversies in what were significant factors and there were few studies so far comparing the therapeutic outcomes in patients treated with immunoglobulin. This study was aimed to determine the prognostic factors which affected the therapeutic outcome of Guillain-Barre syndrome treated with intravenous immunoglobulin. Method: We retrospectively reviewed the medical records of patients with Guillain-Barre syndrome admitted to our hospital between January 1999 and March 2004. All patients were treated with intravenous immunoglobulin. Outcome and prognosis were followed up after four weeks using the overall disability sum score. Results: Thirty-six patients were enrolled in this study. According to the clinical and electrophysiological findings, 17 patients were AIDP, 10 were axonal forms, two were mixed and seven had electrophysiologically no evidence of abnormalities. At a follow-up of four weeks, disabilities at the nadir (p<0.001) and admission (P<0.012), initial manifestations of bulbar symptom (P<0.024) and electrodiagnostic features (P<0.013) were significantly correlated with outcome in patients treated with intravenous immunoglobulin. But only disabilities at the nadir (P<0.033) and electrodiagnostic features (P<0.018) were significant in the multivariate logistic regression analysis. Conclusion: Among the patient treated with intravenous immunoglobulin, the outcomes were significantly different according to the neurological status at the nadir. Therefore early diagnosis, administration of intravenous immunoglobulin and preventing complications during acute stages are essential to minimize neurological deficit and shorten the periods of recovery.

• 한방재활의학과학회지
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• 제25권1호
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• pp.95-101
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• 2015

Objectives The purpose of this case is to report the improvement after Korean medical combined treatment about patient with Guillain-Barre syndrome. Methods We treated patient using electroacupuncture, moxibustion, herbal medication, and rehabilitation therapy for 59 days. Results The weakness of muscles of upper extremities were recovered to normal level, and the muscle power of lower extremities was improved enough to walking with walker. Conclusions We conclude that Korean medical combined treatment is an effective to improve the power of muscle having weakness. But there is a limit on this report due to sufficient number of case. Further studies will be needed.

• Annals of Clinical Neurophysiology
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• 제10권1호
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• pp.70-73
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• 2008

By definition, the time to reach nadir in Guillain-Barre syndrome (GBS) is within four weeks. This is in contrast to the chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), which progress for at least two months. However, CIDP can take a relapsing and remitting form and could mimic treatment related fluctuations of GBS (GBS-TRFs) especially during the early phase of disease. We report a patient with CIDP who initially presented with a rapidly progressive limb weakness mimicking GBS, but finally showed good recovery after long term corticosteroid therapy.

• Annals of Clinical Neurophysiology
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• 제7권1호
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• pp.25-27
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• 2005

The Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy marked by flaccid areflexic paralysis. Although the pathogenesis of GBS remains incompletely defined, considered as an autoimmune disease most frequently triggered by an previous infection. Antecedent infections with Campylobacter jejuni, cytomegalovirus, Ebstein-Barr virus, Mycoplasma pneumoniae, Haemophilus influenzae, human immunodeficiency virus, enterovirus, rotavirus are common. But, it is rare that GBS following typhoid fever. We present a case of typical GBS after antecedent Salmonella typhi infection.

• Clinical Pain
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• 제18권2호
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• pp.111-114
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• 2019

Guillain-Barre syndrome (GBS) is usually characterized by acute areflexic ascending paralysis with minimal sensory involvement. Only a few cases of GBS associated with scrub typhus have been reported. Previous case reports focused on the laboratory findings, pathogenesis, and clinical manifestation. Unlike the previous case, neuropathic pain was a prominent symptom of GBS in our case. We report scrub-typhus-related GBS with a detailed description of the clinical manifestations, especially neuropathic pain, along with results of serial follow-up electrodiagnostic studies.

• Annals of Clinical Neurophysiology
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• 제13권1호
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• pp.54-57
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• 2011

The Guillain-Barre Sydrome (GBS) is post-infectious autoimmune disease and it could be caused by auto-antibodies produced after infections. Mycoplasma pneumoniae is one of rare cause of GBS and known to be associated with antibody to galactocerebroside (GalC) which is a major neutral glycolipid constituent of myelin. We report a case of GBS with immunoglobulin M GalC antibody after M. pneumoniae infection.

• Annals of Clinical Neurophysiology
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• 제4권1호
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• pp.60-62
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• 2002

Two separate cranial nerve variants of Guillain-Barre syndrome(GBS) have been reported. One is Miller-Fisher syndrome, the other is polyneuritis cranialis. Involvement of the extraocular muscles in variants of GBS is well recognized, but complete external and internal opthalmoplegia is rare. Optic neuritis remains the only consistent, albeit very uncommon, evidence of inflammation of central nervous system myelin in GBS. This propose that GBS is part of a spectrum of central and peripheral inflammation. This case is an unusual clinical variant who had ptosis, opthalmoplegia, areflexia, ataxia, optic neurritis, marked oropharyngeal, and neck and shoulder weakness. This combined regional from is able to misdiagnose initially as botulism or diphtheria and less so, myasthenia. So if we were consider variant from of GBS, it is possible for make a correct diagnosis more easily and treatment without delay.

• Journal of Chest Surgery
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• 제35권11호
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• pp.835-838
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• 2002

편평상피 세포암으로 우측 폐 상엽 절제술을 시행한 68세 남자 환자에서 나타난 기엥바레 증후군에 대하여 보고하고자 한다. 환자는 수술 후 6일 째 갑작스럽고 양측성의 하지의 근력약화 및 호흡부전과 감각실조를 호소했다. 응급으로 기관내 삽관 후 인공환기기를 거치했다. 근력 약화 후 2일, 20일, 40일째 전기진단적 검사를 시행하였다. 운동신경전도장애가 현저하게 나타났다. 지속적인 운동말단신경잠시, 전도 시간의 분산, 부분적인 운동신경전도차단이 나타났으며 이와 같은 것들은 기엥바레 증후군의 진단적 특징이다. 보조적인 치료와 함께 정주적 면역 글로불린의 부가적인 사용을 시행하였으며 병세는 근력 약화 후 6주만에 회복되었다.

• 대한한방내과학회지
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• 제25권4호
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• pp.418-425
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• 2004

The Guillain-Barre Syndrome(GBS), also called acute inflammatory demyelinating polyneuropathy and Landry's ascending paralysis, is an inflammatory disorder of the peripheral nerves - those outside the brain and spinal cord. It is characterized by the rapid onset of weakness and, often, paralysis of the legs, arms, breathing muscles and face. Finally, it leads to respiratory embarrassment and death. There is often a history of antecedent respiratory or gastrointestinal infection. Recently one patient was admitted with GBS. This patient was a 30 year-old man with quadriparesis, both facial palsy, numbness of hands and feet, and gait disturbance. After two weeks of oriental medicine and acupuncture treatment most symptoms improved. Therefore, this application of oriental medicine is reported with a plea for further investigation.