• Tuberculosis and Respiratory Diseases
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• 제85권4호
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• pp.341-348
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• 2022

Background: An accurate diagnosis in patients with interstitial lung diseases (ILDs) by multidisciplinary discussion (MDD) based on histopathologic information is essential for optimal treatment. Transbronchial lung cryobiopsy (TBLC) has increasingly been used as a diagnostic alternative to surgical lung biopsy. This study aimed to evaluate the appropriate methods of TBLC in patients with ILD in Korea. Methods: A total of 27 patients who underwent TBLC were included. TBLC procedure details and clinical MDD diagnosis using TBLC histopathologic information were retrospectively analyzed. Results: All procedures were performed under general anesthesia with the fluoroscopic guidance in the operation room using flexible bronchoscopy and endobronchial balloon blocker. The median procedure duration was less than 30 minutes, and the median number of biopsies per participant was 2. Most of the bleeding after TBLC was not severe, and the rate of pneumothorax was 25.9%. The most common histopathologic pattern was alternative (48.2%), followed by indeterminate (33.3%) and usual interstitial pneumonia (UIP)/probable UIP (18.5%). In the MDD after TBLC, the most common diagnosis was idiopathic pulmonary fibrosis (33.3%), followed by smoking-related ILD (25.9%), nonspecific interstitial pneumonia (18.6%), unclassifiable-ILD (14.8%), and others (7.4%). Conclusion: This first single-center experience showed that TBLC using a flexible bronchoscopy and endobronchial balloon blocker with the fluoroscopic guidance under general anesthesia may be a safe and adequate diagnostic method for ILD patients in Korea. The diagnostic yield of MDD was 85.2%. Further studies are needed to evaluate the diagnostic yield and confidence of TBLC.

• Korean Journal of Radiology
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• 제21권7호
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• pp.779-792
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• 2020

Recent advances in computer technology have generated a new area of research known as radiomics. Radiomics is defined as the high throughput extraction and analysis of quantitative features from imaging data. Radiomic features provide information on the gray-scale patterns, inter-pixel relationships, as well as shape and spectral properties of radiological images. Moreover, these features can be used to develop computational models that may serve as a tool for personalized diagnosis and treatment guidance. Although radiomics is becoming popular and widely used in oncology, many problems such as overfitting and reproducibility issues remain unresolved. In this review, we will outline the steps of radiomics used for oncology, specifically addressing applications for breast cancer patients and focusing on technical issues.

• 대한기관식도과학회지
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• 제13권2호
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• pp.65-67
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• 2007

Congenital epiglottic cyst is rare cause of stridor in neonate and if managed inadequately, disaster such as death can occur. Diagnosis of congenital epiglottic cyst includes imaging studies and endoscopy. Fiberoptic or rigid endoscopic examination excludes other causes of stridor in neonate. Complete excision of cyst is treatment of choice under suspension laryngoscopic guidance. Here, we report a case of congenital epiglottic cyst and concomitant laryngomalacia presenting with seizure and respiratory difficulty in neonate with a review of literature.

• 대한치과보철학회지
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• 제62권1호
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• pp.28-37
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• 2024

심한 하악 전돌증이 있는 환자의 경우 교정치료나 악교정수술을 활용하여 치료를 시도할 수 있으나, 장기간의 교정치료 및 수술의 침습적인 거부감이 있는 환자에서 보철적으로만 개선해야 하는 상황이 존재할 수 있다. 골격성 III급 부정교합 환자는 전방유도가 없으며, 수직적인 저작 양식을 보여주기 때문에 이러한 측면을 고려하여 치료하는 것이 중요하다. 또한, 전치부의 반대교합을 개선하기 위한 방법으로 교합수직고경을 거상하는 술식을 선택하기 쉬운데, 이는 종종 불리한 결과를 야기할 수 있으므로 신중한 진단 및 치료계획의 수립이 필요하다. 본 증례에서는 하악 전돌 및 비대칭을 가진 환자에서 단계적인 치료과정을 통하여 기존의 교합수직고경을 그대로 유지하며 임플란트 및 자연치를 이용한 최종 고정성 보철 수복을 진행하였다. 이에 기능적이고 심미적으로 적절한 결과를 보여, 환자의 진단 및 치료 과정에 대해 보고하고자 한다.

• Journal of Acupuncture Research
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• 제41권
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• pp.160-167
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• 2024

The present study employs the Delphi method to devise a consensus-based protocol for utilizing integrated acupuncture in treating medial tibial stress syndrome (MTSS). Twenty acupuncture experts contributed opinions across six key themes, including diagnosis, acupuncture points, additional Traditional Oriental Medicine modalities, treatment rationale, treatment duration/frequency, and integration of yoga/naturopathic therapies. Consensus, defined as a 70% agreement or higher, was reached on all themes, reflecting a collective acknowledgment of the necessity for a holistic approach to MTSS management. The final protocol includes six diagnostic criteria, six acupuncture points, one additional modality, two Traditional Oriental Medicine therapies, four treatment rationales, and six yoga/naturopathic therapies. The present comprehensive protocol offers valuable guidance for healthcare professionals seeking an integrated approach to MTSS management.

• 생물정신의학
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• 제12권2호
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• pp.151-158
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• 2005

Background:Clozapine is a unique atypical antipsychotic medication. It is considered to be superior, even amongst the newer agents, in treatment-resistant schizophrenia. However, de novo emergence or exacerbation of obsessive-compulsive(OC) symptoms during treatment with clozapine has been reported. We prospectively evaluated 19 cases which newly developed OC symptoms during clozapine treatment and discussed the treatment of OC symptoms induced by it. Methods:We recruited 19 patients(8 males, 11 females) with a DSM-IV diagnosis of schizophrenia and schizoaffective disorder who had developed OC symptoms during clozapine treatment. OC symptoms were assessed using the Padua-ICMA and YBOCS on a monthly basis over three months. Results:Eleven female and eight male patients were enrolled and the average age of patients was 32.8 years. At baseline, no patients showed OC symptoms. Moderate to severe OC symptoms appeared with mean daily dose of 298.68 mg of clozapine. There were no significant differences in improving OC symptoms between the clozapine dose reduction group and the OC treatment group. Conclusion:We noticed the possibility that the appearance of OC symptoms is connected with the effect of clozapine. The clozapine-induced OC symptoms were improved both by reducing clozapine daily doses, and by adding OC treatment drugs. With other atypical antipsychotics now available, to know and treat the side effects of clozapine would be of considerable value, offering clinical guidance in making a decision on treatment-resistant schizophrenia.

• Journal of Trauma and Injury
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• 제36권3호
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• pp.269-275
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• 2023

A Morel-Lavallée lesion results from a degloving injury between the muscle fascia and the subcutaneous layer. It is most commonly found in the trochanteric area but can occur at other sites. The treatment of the condition varies according to the medical circumstances, as well as the size and chronicity of the condition. A case of large (18×6 and 10×5 cm) bilateral posttraumatic Morel-Lavallée lesions with no underlying bone fracture is presented; the case occurred in a 49-year-old male patient 4 weeks posttrauma. Ultrasound scans showed bilateral large collections of anechoic fluid, which were aspirated under ultrasound guidance and further managed by compression bandages. There were no further complications. The objective of this case report is to present this unique and educational case, as well as to provide an overview of the pathophysiology, diagnosis, and management of Morel-Lavallée lesions. We conclude by discussing the importance of having a high index of suspicion to ensure early detection and prompt treatment of such lesions to avoid complications.

• 대한정형외과 초음파학회지
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• 제8권1호
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• pp.26-30
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• 2015

정형외과적 영역에서 족부 족관절 부의의 손상은 흔한 문제이다. 비록 손상들이 생명을 위협하지는 않지만 정확한 진단이나 치료가 지연됐을 시에는 하지의 기능에 장애를 유발 할 수 있으므로 정확한 진단이 장기간의 합병증을 예방 할 수 있다. 초음파는 비용-효과면에서 우수하고 방사선 피폭의 염려가 없으며 연부 조직의 검사에 유용하고 역동적 검사를 시행할 수 있어서 아킬레스건 파열에서 그 유용성이 증가하고 있다. 초음파 영상은 아킬레스건 파열의 진단적 도구이다. 영상의학적 검사 없이 아킬레스건 파열을 진단하기 위해서는 신체 검사와 환자의 병력에 필요하지만 개인 의원에서는 약 20%에서 파열을 놓지는 것으로 알려져 있다. 초음파 영상 하에서 정상적인 섬유 구조의 단절이 아킬레스건 파열의 진단이 되며 실시간으로 족배 굴곡 및 족저 굴곡을 함으로써 단절이 더 확대되는 것을 관찰 할 수 있다. 그리고 수술 후나 보존적인 치료를 시행하는 경우에도 추시 관찰 기간 동안 지속적으로 초음파를 통해 건의 상태를 관찰할 수 있는 유용한 도구이다.

• 대한치과보철학회지
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• 제60권4호
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• pp.301-312
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• 2022

광범위한 전악 보철 수복 시 적절한 교합 수직 고경(occlusal vertical dimension)의 설정은 성공적인 치료를 위해 매우 중요한 단계이자 치료의 시작점이 된다. 수직 고경의 변경을 통한 술식은 치료가 침습적일 수 있으며, 환자 및 임상의들의 많은 시간과 비용, 노력을 필요로 하기 때문에, 진단 및 치료 진행 과정에 다각적인 분석과 심도 깊은 고찰이 필수적이다. 본 논문에서는 선행 문헌들의 검토를 통해 수직 고경의 개념과 관련된 여러 쟁점들에 대해 정리하고, 다양한 수직 고경 평가법들을 정리하여 전악 구강 회복 치료 시 적절한 수직 고경을 설정하기 위한 임상적 방법과 이에 대한 근거를 제시하고자 한다.

• Archives of Plastic Surgery
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• 제45권6호
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• pp.512-516
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• 2018

Background Dermoid cysts are congenital tumors that are benign. Dermoid cysts with intracranial extension can cause serious neurological complications. It is important, therefore, to determine whether a patient has a dermoid cyst when their chief concern at a doctor's visit is a mass in the head or neck area. In this study, we present a literature review of dermoid cysts and an analysis of the authors' experiences, with the goal of providing guidance useful for the diagnosis and treatment of dermoid cysts. Methods This study retrospectively analyzed the medical records of 62 patients who visited the two medical clinics with which the authors are affiliated. The patients were enrolled between October 2003 and January 2017. Results Of the 62 patients analyzed in this study, 32 were 0 to 5 years of age (52%) and 23 were 17 years of age or older (37%). Forty-seven patients underwent 1 or more imaging study during the process of diagnosis. Thirty-two patients were suspected to have a dermoid cyst. Forty-nine patients were analyzed to determine the depth of the cyst. Bone was seen in 43 patients through imaging tests or during actual surgery, and nine of the 43 had bony problems (21%). Conclusions This study found that dermoid cysts were present in many adults, and that a high rate of deep lesions was observed, as well as many cases in which even the bone was affected. These results suggest, therefore, that dermoid cysts should be considered, and medical professionals should actively conduct imaging studies.