• Journal of dental hygiene science
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• v.20 no.2
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• pp.118-124
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• 2020

The purpose of this comparison of case reports is to introduce the results of the application of new devices for the management of growing Class III malocclusions in children. Two 8-year-old boys had a chief complaint of anterior crossbite. Anterior crossbite correction using a tandem traction bow appliance (TTBA) or a Carriere Motion 3D Class III appliance with a Transforce appliance was planned. By comparing cephalometric radiographs before and after treatment, changes in skeletal growth and incisor inclination to the Frankfort horizontal (FH) plane could be measured. Both devices increased SNA and ANB angles, N-I Pg-A, U1 to SN, and U1 to FH. Both appliances improved facial features and resolution of anterior crossbite. The TTBA and Carriere Motion 3D Class III appliance had similar effects when applied as early treatment for growing mesio-occlusions and anterior crossbite in two boys. However, long-term outcome assessments and well-designed comparative studies are still required.

• Journal of Microbiology
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• v.41 no.2
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• pp.63-72
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• 2003

Chronic inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis, affects around 2 in every 1000 individuals in western countries and its incidence, particularly amongst children, is increasing. IBD shows extreme morbidity with impact on all aspects of quality of life. If left untreated, IBD can lead to death. Conventional treatment of IBD involves powerful immunosuppressive chemotherapies and surgical intervention. Long-term anti-inflammatory medication is required and so patients are often subject to a spectrum of unpleasant side effects. Interleukin-10 (IL-10) is a cytokine that acts to suppress inflammation. When however administered by injection, the high levels of IL-10 that are distributed throughout the body also lead to side effects. Lactococcus lactis can be genetically engineered to secrete biologically active cytokines. When applied to the mucosa, these L. lactis can actively deliver such cytokines. By use of this principle we developed a new therapeutic approach for IBD. Administration of L. lactis that secretes murine IL-10 cures and prevents IBD in mice. The use of the engineered L. lactis gets around the problem of delivering IL-10, allowing dramatic reduction of the effective dose. A sincere concern exists about the possible dangers of uncontrolled, deliberate release of genetically modified microorganisms, such as could occur following application in healthcare. We engaged in the establishment of adequate means for biological growth control of engineered L. lactis by targeted gene exchange between thyA and hIL-10.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.4
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• pp.893-898
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• 1996

The occlusal disharmonies resulted from labially protruded or malpositioned teeth can damage the periodontium and induce the non-inflammatory gingival recession. For these cases, a conservative approach was performed by improving oral hygiene and correcting the axial and positional status of the gingivally recessed teeth and removing the prematurely contacted areas. In some cases, rapid remission of tooth mobility and gradual decrease of gingival recession was observed just after start of treatment. In cases of gingival recession in permanent lower incisors of the children with mixed dentition, the treatment of choice is non-surgical conservative approaches. In cases when the gingival inflammation can be controlled through reinforcing the oral hygiene, when attached gingiva have a potential to increase in width through growth (not more than 1 year after eruption or not yet arrived at adult level), and when the recession can be corrected by moving the teeth from labial cortical plate through orthodontic treatment, the conservative measures would be the first choice. On the contrary, when recession has exceeded beyond the level of CEJ, when the gingival inflammation existed with the cause of poor oral hygiene, when the attached gingiva have little potential to increase (for example, more than 8 years after eruption), and when the conservative measures yielded no benefit after 4-8 weeks of treatment, the surgical approaches should be sought.

• Korean Institute of Interior Design Journal
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• v.14 no.4 s.51
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• pp.79-86
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• 2005

According to the new multi-media appeared as a result of rapid growth of the information and science technique, the school library must be changed to the integration of the teach-study media resource from the existing print media. It means that the school library has to play a role of the study center with a different media from the existing teaching material, teaching instrument, facility and opportunity. The Information education must be conducted in the way of an integrated education course and able to do both information transaction and problem settlement. The education facility to solve this problem is the school library. Therefore, the school library becomes important more and more. It means that the school library is the center of entire study and education material for the teacher and student is focused on it. It is urgent to make the standard of the school library In order to cope with the new education and information environments. And especially it is very important to make a plan about the location and scale of the school library to improve the quality of the children's studying activity. The location of the school library is decided under consideration of the relationship with other room of school house and the proper scale of it is between 2.5units and 7.0units of classroom based on the number of class.

• Korean Journal of Child Studies
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• v.37 no.2
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• pp.143-155
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• 2016

Objective: The purpose of the study was to investigate the effects of psychological well-being on married immigrant women's parenting efficacy. Methods: The participants consisted of 145 married immigrant mothers who were members of multi-cultural family support centers in Andong, Young-ju, Uiseung, and Munkyung cities in Gyeongsangbuk-do province. Results: The main results are as follows. First, the levels of language competence and education were significantly related to psychological well-being, suggesting that the level of language competence as well as the level of education could be main factors for psychological well-being. Further, numbers of children and monthly household income were significantly related to parenting efficacy. Second, psychological well-being was correlated with parenting efficacy of married immigrant women, demonstrating that psychological well-being was the most effective variable for parenting efficacy. Third, self-acceptance, environmental mastery, and personal growth in the psychological well-being significantly predicted parenting efficacy. Conclusion: These findings suggested that we should reconsider the importance of psychological well-being in supporting programs for parenting.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.5
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• pp.1180-1186
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• 1999

A wide ranges of chemicals released into the environment have potential to interfere with physiological and development process by disrupting endocrine pathways. Endocrine system embraces a multitude of mechanisms of action, including effect on growth, behavior, reproduction and immune function. These environmental endocrine disruptors are present in environment and pose potential health consequences to human and wildlife. The best known form in endocrine distruptors involves substances which mimic or block the action of natural hormone in the body. Endocrine disruptor have been variously defined as exogenous agents that interfere with the synthesis, secretion, transport, metabolism, binding action or elimination of the natural hormones in the body which are responsible for the maintenance of homeostasis, reproduction developmental and/or behavior. Many compounds polluted into the environment by human activity are capable of disrupting the endocrine system of animals, including fish, wildlife, and humans. Among these chemicals are pesticides, industrial chemicals, and other anthropogenic products. It has been alleged that several adverse effects on human health are linked with exposure to chemicals which are claimed to be endocrine disrupters, that is, increased incidence of testicular, prostate and female breast cancer, time dependent reductions in sperm quality and quantity, increased incidence of cryptorchidism (undescended testicles) and hypospadias(malformation of the penis), altered physical and mental de velopment in children. This observation is currently the only example of chemically mediated endocrine disruption which has resulted in a clear effect at the population level.

• Toxicological Research
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• v.21 no.4
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• pp.271-278
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• 2005

Reproductive and developmental toxicology is concerned with various physical or chemical agents interfering with fertility in both gender or normal growth of offsprings. Reproductive and developmental toxicology is rather a complex science, with many fields, i.e., various endpoints are involved and many different mechanisms of action. For that reason, diverse aspects must be considered when attempting to assess possible adverse health effects in the area of reproductive and developmental toxicology. The thalidomide tragedy made it clear to regulatory authorities around the world that systematic, comprehensive evaluation of the reproductive cycle was needed to adequately evaluate the potential of medicinal drugs to impair the process of reproduction or the development of embryos, fetuses, and children. International Conference on Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use (ICH) and U.S. Food and Drug Administration (FDA) developed a guideline to assess the reproductive and developmental toxicity. Also these guidelines have since been applied to the detection and regulation of environmental toxicants, food additives, and so on. Although it was hoped that testing procedures of guideline would be updated constantly to reflect the current state of the science in reproductive and developmental toxicology, it was not until this decade that regulatory guidelines and testing methods have been altered in a significant way. In this paper, we would like to present the recommended approaches and recent trends for improvement of testing guidelines or experimental methods in reproductive and developmental toxicology.

• The Journal of Korean Academic Society of Nursing Education
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• v.25 no.4
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• pp.459-470
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• 2019

Purpose: The purpose of this qualitative study was to identify the nature of precocious puberty and to explore what it means in primary schools. Methods: The participants of this phenomenological study were nine primary school girls who were diagnosed with precocious puberty and experienced hormone therapeutics, applying a convenience sampling method. Data were collected from July 2017 to January 2018 through individual in-depth interviews of the participants, including gestures, facial expressions and nonverbal means. The data analysis followed the method of Giorgi. Results: The study identified 37 concepts, 12 clusters, and five themes from experiences of precocious puberty. The essential five themes were as follows: 'ashamed and concealing experience', 'there is no therapeutics option', 'difficulties in the process of therapeutics', 'difficulties in daily life', and 'ambivalence toward therapeutics'. Conclusion: The findings of this study indicate physical, psychological and social difficulties faced by girls with precocious puberty. Based on this results of the study, it is necessary to develop nursing intervention programs focusing on healthy growth and development for children with precocious puberty.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.12
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• pp.391-397
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• 2021

One of the sustainable development goals is to promote good health and well-being for all people. Child health is a top priority since their health issues can have a detrimental impact on human capital development, which is a critical input for the growth model. This paper applies the health production model to explore the determinants that influence the health of children under the age of five. The results of a survey of 203 households in Ho Chi Minh City, Vietnam, were examined. Child health is measured using anthropometric indicators such as weight-for-age, height-for-age, and weight-for-height (ZWFH). Three separate multinomial logistic models are regressed to examine the drivers of child health as proxied by z-score weight for age, z-score height for age, and z-score weight for height. The significance of input variables relating to a child's attributes, household, and environment was validated by the findings. The inclusion of overweight besides under-nourished indexes is novel because it reflects the current trend of child over-nutrition. The findings of the study highlight the importance of a wide range of initiatives to enhance child health. Moreover, the genetic effect is found to be crowded out by environmental and household factors. The finding verifies that despite their parents' moderate height, the future generation of Vietnamese can achieve the desired height.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.487-494
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• 2016

This study aimed to visualize a pig character targeting the golden pig in Geuknakjeon of Bulguksa Temple. As for a pig, it is included in this list of the 12 Chinese zodiac animals and controls Haeshinjang. Today, the characters market is enjoying rapid growth due to diversification of platforms. However, we do not see many characters made out of Korean traditional cultures and customs. This study first looks into significance of pigs that are often observed in Korean traditional culture and then offers possibilities of their being transformed into contemporary characters. In order to achieve the research goals, the study shed new light on the golden pig in Bulguksa Temple. As making contemporary applications to , the study proceeded with work of visualization. As for a face of a character, the study focused on that of the pig but regarding a body, the study applied a man's body. After all, the study came up with this SD character in a second-proportioned figure. This study discuses formative characteristics of existing Buddhist cultural assets and uses the character for improving understanding on Korean traditional culture. In the future, the study will propose ideas on animation contents development targeting infants and children.