• 제목/요약/키워드: Growth of Solid

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구강 편평세포암종에서 태반성장인자의 발현 (EXPRESSION OF PLACENTA GROWTH FACTOR IN THE ORAL SQUAMOUS CELL CARCINOMA)

  • 이상구;김철환
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제31권1호
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    • pp.27-34
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    • 2009
  • Angiogenesis is essential for solid tumor growth and progression. Among the pro-angiogenetic factors, vascular endothelial growth factor(VEGF), also known as vascular permeability factor, is the most important as a mitogen for vascular endothelium. The VEGF family of molecules currently consists of six growth factors, VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and placenta growth factor(PlGF). Over-expression of PlGF is associated with angiogenesis under pathological conditions such as ischemia, inflammation, and cancer. Hence, the goal of this study is to identify the correlation of clinicopathlogical factors and the up-regulation of PlGF expression in oral squamous cell carcinoma. We studied the immunohistochemical staining of PlGF, PlGF gene expression and a real time quantitative RT-PCR in 20 specimens of 20 patients with oral squamous cell carcinoma. The results were as follows. 1. In the immunohistochemical study of poorly differentiated and invasive oral squamous cell carcinoma, the high level staining of PlGF was observed. And the correlation between immunohistopathological PlGF expression and histological differentiation of specimens was significant (Pearson correlation analysis, significance [r] >0.6, P < .05). 2. In the PlGF gene RT-PCR analysis, PlGF expression was more in tumor tissue than in adjacent normal tissue. Paired-samples analysis determined the difference of PlGF mRNA expression level between the cancer tissue and the normal tissue (Student's t - test, P < .05) These findings suggest that up-regulation of the PlGF gene may play a role in progression and local metastasis in invasive oral squamous cell carcinoma.

Characteristics of mycelial growth and fruit body of Sparassis latifolia strains and selection of suitable incubation conditions in liquid spawn

  • Lee, Yunhae;Gwon, Heemin;Jeon, Daehoon;Choi, Jongin;Lee, Youngsoon
    • 한국균학회소식:학술대회논문집
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    • 한국균학회 2018년도 춘계학술대회 및 임시총회
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    • pp.29-29
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    • 2018
  • Sparassis latifolia is called "Cauliflower Mushroom" and is known as an edible mushroom that has high content of ${\beta}$-glucan. Recently, artificial cultivation of S. latifolia has been done by bottle, plastic bag and wood cultivation in Korea. However it is not widely used because there are low incubation ratio and yield. For the high efficiency of production, we aim to find the superior strains and media for better mycelial and fruit body growth. First, we analyzed the genetic relationship among 31 strains and divided five groups with three kinds of URP primers. And then ten strains were selected from five groups based on the experiment of mycelial growth. The suitability of media for mycelial growth was different according to media type. The suitable solid and liquid media for mycelial growth of S. latifolia isolates were PDA and M2, respectively. In addition, with regard to C/N ratio, the mycelial growth increased even until C/N 160. Second, we investigated the production of fruitbody of the strains by plastic bag cultivation. The substrate was mixed with larch sawdust, corn flour, and wheat flour (8:1:1, v/v). Moisture content of substrate was controlled by about 60% with 10% molasses solution. Out of 31 strains, 19 strains formed primordia. The eight strains produced more than 140g/1kg in fresh weight. Third, molasses culture media was selected for the mycelial growth. And molasses suitable sugar content and input aeration were around 8Brix% and 0.3~0.6vvm, respectively. The longer the incubation period is, the more dried weight of mycelia increased, but medium volume decreased. Therefore, the best incubation period was 9 to 11 days depending on strains. In the future, research project entitled development of culture system and new variety for stable production of S. latifolia will be considered as a new item.

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인삼 조 Saponin과 조즙액이 인삼근부병균 Fusarium solani와 Erwinia carotovora의 생육에 미치는 영향 (Effect of crude ginseng saponin and raw ginseng juice on the growth of ginseng root rot organisms, Fusarium solani and Erwinia carotovora)

  • 박창석;오승환
    • 한국응용곤충학회지
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    • 제20권1호
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    • pp.1-5
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    • 1981
  • 인삼 조사포닌과 인삼즙액이 인삼 근부패를 일으키는 병원균 Fusarium solani와 Erwinia carotovora의 생장과 증식 및 포자발아에 미치는 영향을 조사하여 다음과 같은 결과를 얻었다. 1. 인삼 조 Saponin의 농도가 증가됨에 따라 F. solani의 대형분생포자의 발아율은 억제 되었으며 500 ppm 이상 첨가시 현저하게 억제 되었다. 2. 토양 추출액은 초기에 F. solani의 포자 발아를 억제하는 효과가 있었으나 24시간후에는 무효화되었다. 3. 인삼 조 Saponin의 첨가 농도가 증가됨에 따라 F. solani의 포자형성량이 감소되었으며 고체배지에서 이러한 현상은 더욱 뚜렷하게 나타났다. 4. 인삼 Saponin을 첨가 했을시 균사생장량은 약간 감소되었으나 농도에 따른 감소율은 인정되지 않았다. 5. 인삼 조 사포닌은 농도가 증가 될 수록 F. solani의 Colony 형성을 억제하였으나 인삼즙액은 농도가 증가될수록 현저하게 F. solani의 Colony수를 증가시켰다. 6. 인삼 조 Saponin과 인삼즙액 모두 E. carotovora의 생장을 촉진시켰다.

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수치모델을 이용한 고성만 양식 참굴의 연구 -I. 먹이가 참굴의 성장에 미치는 영향- (Modeling Oyster Populations Dynamics -I. Effect of Available Food on Growth of the Pacific Oyster Crassostrea gigas in Goseong Bay, Korea-)

  • 오경희;방익찬;;김윤;김성연;박윤정;최광식
    • 한국수산과학회지
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    • 제35권4호
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    • pp.327-335
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    • 2002
  • Effects of available food on growth of commercially cultured Pacific oysters, Crassostrea gigas in Goseong Bay on the south coast were studied using a numerical model. levels of total protein, carbohydrate and lipid in particulate organic matter in the water column as well as chlorophyll a concentration were determined for estimating total available food for oyster growth. Environmental parameters including water temperature, salinity and total suspended solid were also monitored for the model. Oyster growth was also monitored by means of measuring shell length and tissue wet weight increase on a monthly basis. Simulation results from the numerical model indicated that chlorophyll a is not a good representative of available food for the oysters in Goseong Bay. In contrast, available food in the water column measured by filtration of the organic particles and analyzed in terms of total lipids, carbohydrates and protein was well matched with simulated oyster growth in the Bay which is similar to observed growth. The model also suggested that oysters have relatively low retention efficiency of $50\%$ or less. This result indicates that oysters in the bay utilize only a part of food particle available in the water column, as reported in other studies.

카리장석의 유기농 무와 비트 생육촉진효과 (Effect of Potash Feldspar on the Growth of Organic Radish and Beet)

  • 심창기;김민정;김용기;홍성준;박종호;한은정;김석철;이승복
    • 한국유기농업학회지
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    • 제24권3호
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    • pp.413-425
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    • 2016
  • 칼륨(K)은 식물의 생육에 필요한 기본 요소 중의 하나이다. 본 연구는 분상, 입상, 사상의 카리장석 제형별로 유기농 무와 비트의 생육에 미치는 영향을 구명하고자 수행하였다. 시설하우스에서 15일 육묘한 무와 비트 묘를 정식하기 전에 3종의 0.1% 카리장석을 토양에 혼화 처리하였다. 처리한 모든 종류의 카리장석은 무와 비트의 뿌리 경도를 제외하고 무처리에 비해 유의적으로 무와 비트의 뿌리, 줄기생육 및 당도를 향상시켰다. 특히, 분상 카리장석이 가장 효과적으로 무와 비트의 생육을 촉진하였다. 농가에서 유기농 비트와 무의 근권에 카리장석을 시용할 경우 지상부와 지하부의 생육을 촉진할 수 있을 것으로 판단한다.

열처리 조건에 따른 이온주입된 실리콘의 재결정화 (Thermal Annealing Condition Dependence of Ion-implanted Silicon Recrystallization)

  • 이창희;이순일
    • 한국진공학회지
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    • 제4권4호
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    • pp.386-393
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    • 1995
  • 이온주입된 실리콘 시료들의 열처리 조건에 따른 재결정화를 분광 타원해석법(Spectroscopic Ellipsometry, SE)을 사용하여 연구하였다. 열처리 후에도 잔류하는 결함들의 양과 분포를 구하기 위한 시료의 층구조 분석에 있어서 손상층의 유효굴절율은 Bruggeman 유효매질이론을 이용하여 구하였으며 기준 비정질실리콘 데이터로서는 완화된 비정질실리콘의 광학상수와 이온주입에 의해서 만들어진 비정질 실리콘의 광학상수를 함께 사용하였다. 조사된 대부분의 열처리 조건하에서 고체상 적층성장(solid-phase epitaxial growth)과정에 따라 비정질층이 재결정화되는 것이 관측되었다.

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Electrical and Rheological Properties of Colloidal of Alumina Suspensions

  • Wang, Xu-Hong;Yoshihiro Hirata
    • 한국결정성장학회:학술대회논문집
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    • 한국결정성장학회 2000년도 Proceedings of 2000 International Nano Crystals/Ceramics Forum and International Symposium on Intermaterials
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    • pp.215-232
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    • 2000
  • The Valence(Z) of positively and negatively charged alumina particles in the dilute suspensions was analyzed with the electrical conductivity of the suspensions. The mobility of negative particles was lower than that of positive particles at a similar Z value because of the stronger effect of chemical bonding over the hydrated particle surfaces. The apparent viscosity of acidic suspensions of 1-40 vol % solid was lower than that of basic suspensions. This result was discussed based on the three important effects of the valence, concentration and nature of hydrated surface of alumina particles. The density of alumina compacts consolidated by filtration through gypsum molds became lower for the basic suspensions than for the acidic suspensions. This result was correlated to the properties of the colloidal alumina suspensions.

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마그네시아의 소결과 미세구조에 미치는 $TiO_2$의 영향 (Influence of $TiO_2$ on Sintering and Microstructure of Magnesia)

  • 이윤복;박홍채;오기동
    • 한국세라믹학회지
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    • 제31권5호
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    • pp.471-476
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    • 1994
  • The influence of TiO2 addition on the sintering and microstructure of magnesia ceramics was studied. An excess amount of TiO2 over the solid solubility limit reacted with magnesia to form Mg2TiO4 compound above 130$0^{\circ}C$. The deviation of lattice parameter of MgO was estimated to be under 0.2% when existence of TiO2 in MgO. The addition of TiO2 markedly promoted the densification of MgO at comparatively low temperature and the sintered density of about 98% of the theorectical was obtained at 150$0^{\circ}C$, 2h. The densification was mainly governed by grain growth of MgO and the effect of Mg2TiO4 existing as a second phase on depression of grain growth of MgO was not exhibited.

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국내 리매뉴팩쳐링 산업의 활성화 방안에 관한 연구 (A Study on Active Implementations of Remanufacturing Industry in Korea)

  • 김현수;한대희
    • 산업경영시스템학회지
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    • 제23권59호
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    • pp.105-118
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    • 2000
  • The rise in population and the increase of urbanization and industrial growth has resulted in an ever-increasing volume of municipal solid waste that must be regularly collected, transported, and ultimately disposed of. Therefore, over the last decade the public, commercial and legislative awareness of environmental issues has been increased dramatically on earth particularly some industrial countries which has a shortage of landfill capacity. A quality, cost and delivery lead-time are usually considered as the competitive factors for each industry. However, the concepts of environmental issue are emerging common terms and concerns more seriously. More attention than ever is being focused on the recycling and source reduction techniques to reduce the total volume of waste. Unfortunately, however, a shortage of landfill capacity and increasing disposal cost requests a fundamental solution about the environmental issue. That is the remanufacturing which allow manufacturers to minimize waste, production cost and to turn end-of-life product into a profitable product. The objectives of this research were to growth the remanufacturing system by suggesting issues and implementation methods for the remanufacturing. In order to accomplish these objectives, we introduced backgrounds of appearance and benefits of the remanufacturing.

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갈색무늬병의 시기별 이병 및 낙엽 정도가 '후지'/M.9 사과나무의 과실품질 및 신초생장에 미치는 영향 (Influence of Seasonal incidence and Defoliation Degree of Marssonina Blotch on Fruit Quality and Shoot Growth of 'Fuji'/M.9 Apple Tree)

  • 박무용;사공동훈;권헌중;도윤수;송양익;이동혁
    • 원예과학기술지
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    • 제31권5호
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    • pp.523-530
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    • 2013
  • 본 조사연구는 갈색무늬병(Diplocarpon mali Harada et Sawamura)의 시기별 이병 및 낙엽 정도가 '후지'/M.9 사과나무의 신초생장과 과실품질에 미치는 영향을 조사하고자 실시하였다. 2009년 군위지역에서의 갈색무늬병 발생은 7월 중에 시작되었고, 10월 말에 10% 정도 낙엽이 되었다. 2010년에는 갈색무늬병 발생은 6월 초에 시작하였다. 낙엽률은 9월 말에 20%이었고, 10월 말에 50%에 도달하였다. 2010년 정단신초의 이차생장량은 2009년보다 약 3배 더 높았다. 2009년 과실 성숙기 동안의 가용성 고형물 함량과 착색 정도(Hunter a value)는 각각 $13.8^{\circ}Brix$, 16.2까지 올라갔다. 2010년 과실 성숙기 동안의 가용성 고형물 함량은 10월초 이후로 $12.1-12.6^{\circ}Brix$ 범위에 머물렀고, 착색은 낙엽이 20%된 9월 말 이후에 높아지기 시작하였다. 낙엽 정도에 따른 과실품질에 있어, 10월 말 과대지의 낙엽율이 30% 이상이 되면 착색도가 감소되었고, 낙엽율이 50% 이상이 되면 과중과 가용성 고형물 함량이 감소되었다. 10월 말 30% 이상 낙엽구의 과실 종경과 횡경은 30% 미만 낙엽구과 비교해 볼 때, 8월 중순부터 감소되기 시작하였다. 2010년 8월말 과대지에서 이차생장한 부위 잎의 광합성 속도는 기존의 과대지 중간 부위의 잎과 비슷하였다. 그러나 과실의 크기와 가용성 고형물 함량은 과대지의 이차생장한 부위 잎의 광합성 활동에 영향을 받지 않았다.