• 한국심리학회지 : 문화 및 사회문제
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• 제18권4호
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• pp.505-532
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• 2012

이 연구는 청소년학생들의 정신건강에 영향을 주는 성장과정의 상처, 열등감, 성격장애 간 관계를 분석하고자 하였다. 최종 분석대상은 중·고교생 2,119명을 표집, 조사·수집된 자료를 분석했다. 차이분석, 중다회귀분석, 경로분석 결과, 성장과정의 상처, 열등감, 성격장애, 정신건강 요인 면에서 여학생들과 고등학생들이, 그리고 가정경제 환경이 곤란한 학생들과 학업성적 수준이 하위권 학생들이 상대적으로 문제가 있음이 의미 있게 밝혀졌다. 열등감에 영향을 주는 성장과정의 상처 요인은 행복감, 안정감, 인정감의 상처 순으로 유의미하게 영향을 주는 것으로 확인되었고, 성격장애에 영향을 미치는 성장과정의 상처 요인은 행복감, 안정감, 자신감, 사랑, 평등감의 상처 순으로 유의미하게 영향을 주는 것으로 밝혀졌다. 또한 정신건강에 유의미하게 영향을 주는 성장과정의 상처 요인은 행복감, 안정감, 자신감, 사랑, 평등감의 상처 순으로 밝혀졌다. 그리고 정신건강에 미치는 관련변인들의 영향력은 전반적으로 성장과정 상처의 직접효과보다 성격장애와 열등감을 통한 간접효과가 높게 나타났다. 이는 성장과정의 상처가 열등감과 성격장애로 이어지고 궁극적으로 정신건강으로 악화될 수 있다는 교육적 시사점과 함께 가정환경의 건강성과 교육적 성장환경의 중요성을 일깨워 준다.

• Childhood Kidney Diseases
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• 제24권1호
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• pp.14-18
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• 2020

Chronic kidney disease-mineral bone disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism caused by CKD. Patients with early-stage CKD who present with disordered regulation of bone and mineral metabolism may be asymptomatic. However, if untreated, the condition can be a significant barrier in achieving optimal bone strength, linear growth, and cardiovascular health in pediatric patients with CKD. Thus, the current study evaluated the definition, pathogenesis, diagnosis, and management of pediatric CKD-MBD.

• 대한한방소아과학회지
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• 제35권1호
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• pp.18-29
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• 2021

Objectives The purpose of this study is to provide evidence of treatment of growth disorder Methods We have reviewed clinical studies of growth disorder in children and adolescent through 6 databases until February, 2020. The searching keywords were "short stature OR dwarfism OR growth disorder" AND "acupuncture OR electric acupuncture OR electroacupuncture OR moxibustion OR herb medicine OR cupping OR Korean medicine OR oriental medicine OR chuna OR pharmacopuncture OR qigong OR traditional medicine OR traditional Korean medicine OR Korean medicine". There was no limit to time and language. Results As a result of the initial search, a total of 270 papers from six domestic databases were found. Among these papers, 156 papers were selected after excluding duplicated papers, and 109 of them were further excluded after checking the title and the abstract. Additionally, 28 papers were excluded by reviewing the full text. The author, year, number of patients, treatment, evaluation tools, and results of a total of 19 papers were included in this study and were summarized. 90.5% of the studies have shown that herbal remedies have improved childhood growth. Conclusions Random control studies and large-scale observational studies are needed in future to show high-quality evidence for the treatment of Korean medicine in pediatric growth.

• 대한불안의학회지
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• 제3권1호
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• pp.3-7
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• 2007

Anxiety disorder is likely caused by an interaction of multiple loci in brain, rather than a single locus. Hyperactive neurotransmitter circuits between the cortex, thalamus, amygdala, and hypothalamus are responsible for production of anxiety symptoms. Familial studies performed on anxiety disorder suggested that anxiety disorder should be caused by genetic etiology. Numerous linkage and association studies showed different genetic loci of anxiety disorder. Candidate genes have been focused on important neurotransmitters, neuropeptide, or genes affecting neuronal growth, development, protection or apoptosis. Anxiety disorder has various symptoms and comorbid diseases in family or proband. Therefore, further studies focused on symptomatic dimension of anxiety disorder or responses to drugs are required.

• 생물정신의학
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• 제13권1호
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• pp.32-37
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• 2006

Background : Several studies have suggested that alterations of cytokine level could be related to the pathophysiology of bipolar disorder. In this study, we measured plasma level of Interleukin-12(IL-12), a pro-inflammatory cytokine and transforming growth factor-${\beta}$1(TGF-${\beta}$1), an anti-inflammatory cytokine before and after treatment in acute manic patients. Methods : The plasma concentrations of IL-12 and TGF-${\beta}$1 were measured using quantitative ELISA in 18 bipolar disorder patients and 25 normal controls at admission and 6 weeks later. The psychopathology was measured by Brief Psychiatric Rating Scale(BPRS) and Young Mania Rating Scale(YMRS). Results : IL-12 levels were significantly higher in bipolar manic patients than in controls before treatment. Following the 6-week treatment, the IL-12 level was decreased than before treatment, but sustained still higher level than normal control. TGF-${\beta}$1 level was not significant different between manic patients and normal controls before treatment, but was increased after treatment comparing with before treatment in bipolar patients. The ratio of IL-12 and TGF-${\beta}$1 was significantly decreased after treatment. Conclusion : Cytokine abnormalities in bipolar disorder might be involved in the pathophysiology of the illness. It is possible that TGF-${\beta}$1 plays an important role in the regulation of immunological imbalance in bipolar disorder.

• 구강회복응용과학지
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• 제30권2호
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• pp.170-175
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• 2014

성장장애는 두개안면부의 골격성장과 영구치의 조기상실에 영향을 미친다. 본 증례는 성장장애 환자에서 치아를 조기 상실한 부위에 무피판 술식으로 임플란트를 식립 시 컴퓨터 단층촬영(CT)을 통한 인접치아의 확인과 임플란트 가이드의 필요성을 살펴보았다. 특발성 저신장과 3급 정신지체의 20세의 여환에서 구치의 회복을 위해 임플란트 고정성 보철을 계획하였다. CT 영상에서 인접치가 심하게 협측으로 위치되어 있었고, 이를 반영하여 가이드를 제작후 임플란트를 식립하였다. 이상 위치된 인접치를 기준으로 임플란트를 식립할 경우 협측 골의 천공이 발생할 수 있다. 그러므로 성장장애 환자에서 치아 조기 상실부에 임플란트를 식립 시 CT를 통한 치아의 위치 확인과 가이드의 제작이 요구된다.

• Journal of Dairy Science and Biotechnology
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• 제25권1호
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• pp.27-31
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• 2007

Colostrum has lots of bioactive components and many growth factors including insulin-like growth factors, transforming growth factors and epidermal growth factor. Colostrum and milk derived growth factors widely mediate the growth of overall development and could be used as treatment of gastrointestinal disorder, wound repair process, bioacrivity in the neonatal GI tract and induction of oral tolerance. It is possible that milk derived growth factors as potential neutraceuticals for the specific consumers may have a great role in future food industry.

• 대한한방소아과학회지
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• 제27권4호
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• pp.50-56
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• 2013

Objectives The purpose of this study is to evaluate the effect of the herbal medicine in treating digestive system problem on children's growth. Methods We studied 135 children who visited ${\bigcirc}{\bigcirc}$ oriental medical hospital to treat digestive system problem from March 2010 to February 2012. We measured their height and body weight on their first time visit and a year later. We compared them using the Growth Statistics Curve made by the Korean Association of Pediatrics, 2007. Results Generally, total children's average height and weight were significantly increased after the herbal medicine. The difference between the height and weight of treated children and the average height and weight was significant. Conclusions Herbal medicine to treat disorder of digestive system helped growth of children.

• 한국약용작물학회지
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• 제22권2호
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• pp.140-146
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• 2014

This study was carried out to investigate the difference of the content of soil chemical components and growth characteristics in six years old ginseng affected by application of decomposing plant residues in paddy-converted field. The results show that aerial parts of ginseng are no difference between press cake (PC) 200 kg/10a and control but subterranean parts of ginseng PC 200 kg/10a, especially quantity related root fresh weight and tap root diameter, are statically about 1.6 times heavier and about 1.2 times thicker than the ginseng control. Furthermore, the survival rate of PC 200 kg/10a is 67.1% rise significantly compare with the control 50.7%. But compared with the PC 200 kg/10a and the PC 400 kg/10a, ginseng root growth and survival rate of PC 400 kg/10a get worse and that increase physiological disorder occurrence rate than PC 200 kg/10a. Even though there are no significant differences between the ginseng of decomposing plant residues except press cake treatment and the ginseng of control in growth characteristics, it does tend to increase the survival rate and decrease the physiological disorder occurrence rate in most fertilizer treatment except for RSC 2 ton/10a, RSC 4 ton/10a and RH 4 kL/10a. Noted that EC is highly increased and exceeded 1.7 ds/m in RSC 2 ton/10a, RSC 4 ton/10a and RH 4kL/10a. It would be caused physiological disorder in many ways and affected ginseng growth characteristics, survival rate.

• 정신신체의학
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• 제4권1호
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• pp.13-20
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• 1996

This study was performed to explore the frequency of panic attack induced by sodium lactate in alcohol dependence patients and to compare the extent of blunted growth hormone reponses after clonidine infusion with that of normal controls. The authors investigated 10 alcohol dependence patients receiving inpatient care in Hangang Sacred Heart Hospital from March 2, 1993 to August 31, 1993 and 10 normal controls. The disagnosis of alcohol dependence was based on DSM-III-R. Thirty minutes after the sodium lactate infusions clonidins were administrated. Venous bloods were sampled before the sodium lactate infusions, and 30, 45, 60, 90 minutes after the administrations of clonidine. Plasma growth hormone levels were measured by RIA method. The results were as follows : 1) In the questionaires of Hamilton Anxiety Rating Scale, Hamilton Depression Raing Scale, CAGE, Korean MAST, the scores of alcohol dependent patients were higher than those of normal controls. 2) Sixty percent of alcohol dependence patients and twenty percent of normal controls had panic attacks induced by sodium lactate. 3) All panic attacks induced by sodium lactate were relieved after clonidine infusions. 4) There were blunted growth hormone responses after clonidine infusions in alcohol dependence patients who had sodium lactate induced panic attacks like panic disorder patients. These results suggest that alcohol dependence patients may have noradrenergic abnormality same as panic disorder patients and two disorder may have high biological correlations each other.