• Experimental and Molecular Medicine
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• 제50권11호
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• pp.3.1-3.11
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• 2018

This study aimed to verify the effects of estrogen on the onset and development of adolescent idiopathic scoliosis and the mechanisms associated with these effects by constructing a pubescent bipedal rat model. Experiments were conducted to investigate whether scoliosis progression was prevented by a Triptorelin treatment. One hundred twenty bipedal rats were divided into female, OVX (ovariectomy), OVX + E2, Triptorelin, sham, and male groups. According to a spinal radiographic analysis, the scoliosis rates and curve severity of the female and OVX + E2 groups were higher than those in the OVX, Triptorelin, and male groups. The measurements obtained from the sagittal plane of thoracic vertebrae CT confirmed a relatively slower growth of the anterior elements and a faster growth of the posterior elements between T11 and T13 in the female and OVX + E2 groups than in the OVX and Triptorelin groups. Histomorphometry and immunohistochemistry revealed a significantly longer hypertrophic zone of the vertebral cartilage growth plates that expressed more type X collagen and less type II collagen in the OVX and Triptorelin groups than in the female and OVX + E2 groups. Ki67 immunostaining confirmed an increase in the proliferation of vertebral growth plate chondrocytes in the OVX group compared with the female and OVX + E2 groups. In conclusion, estrogen obviously increased the incidence of scoliosis and curve severity in pubescent bipedal rats. The underlying mechanism may be a loss of coupling of the endochondral ossification between the anterior and posterior columns. Triptorelin decreased the incidence of scoliosis and curve magnitudes in bipedal female rats.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제8권1호
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• pp.43-49
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• 1997

본 연구는 아동의 기질특성이 신체발육에 영향을 주는가를 알아보기 위해 설계되었다. Thomas와 Chess에 의해 개발된 기질설문지의 한국 표준화 판을 이용하여 3세에서 7세 사이의 남녀 아동 395명의 기질을 측정하였다. 동시에 각 아동의 신장과 체중을 측정한 후 한국 소아 신체 발육 표준치에 근거하여 신장 및 체중 절대치를 백분율 값으로 전환하였다. 기질의 난이도 지수인 요인 A 점수 및 9가지 기질범주 점수와 신장 및 체중 백분율 값 및 신장에 따른 체중 백분율 값 사이에 상관분석을 실시하였다. 가족 평균 월 수입액에 따라 7단계로 분류한 가정 경제력을 통제변수로 하여 경제력을 통제하였다. 그 결과 기질적으로 어려운 아이일수록 동일 연령의 아동들에 비해 체중이 낮았으며, 동일한 신장을 갖는 아동들 중에서도 체중이 낮은쪽에 포함되었다. 이런 경향은 여자 아동들에서 두드러졌다. 이 결과는 기질특성이 심리적 발달뿐만 아니라 신체 성장과도 관련이 있음을 보여주는 것이다.

• 대한한방소아과학회지
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• 제30권4호
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• pp.87-98
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• 2016

Objectives The purpose of this study is to evaluate the effect of herbal medicine in children's growth. Methods 51 children from the age of 5 to 16 were participated in this study (27 of boys and 24 of girls). The participants were from the department of the pediatrics in Daegu hanny university oriental medical hospital. They were measured their body composition and their bone age, the height percentile of their first and the last visit. Then, those were compared by the Korean Association of Pediatrics' Growth Statistics Curve. Results 1. Generally, total children's average height and weight were significantly increased after the herbal medical treatment. The differences between their height and the general populations' average height, their weight and general populations' average weight were significantly decreased after the treatment. 2. Total children's average soft lean mass, body fat mass, BMI were also significantly increased after the herbal medical treatment. 3. The mean height percentiles of the children has increased by 1.47 percentile. The mean weight percentiles of the children decreased 1.08 percentile. 4. The height percentiles were increased in every group except the group of boys younger than 9 and older than 12 year old. Other than the group of boys younger than 9-year-old and the group of 10-11-year-old boys, every group showed decreasing weight percentile. Conclusions The herbal medical treatment helped children with growth retardation.

• ALGAE
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• 제21권3호
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• pp.311-316
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• 2006

The effects of light quality and irradiance on the growth of Cochlodinium polykrikoides were investigated in the laboratory. At 25°C and 30 psu the irradiance-growth curve was described as μ = 0.34 (I-9.76)/(I+12.5), (r=0.98). This suggests half-saturation photon flux density (PFD) (Ks) of 32.0 μmol photons m–2 s–1, and a compensation PFD (Ic) of 9.76 μmol photons m–2 s–1. Because the Ic equates to a depth of ca. 15.4 m, these responses suggest that irradiance at the depth around and below the thermocline in Yeosuhae Bay would provide favorable conditions for C. polykrikoides. Photoinhibition did not occur at 300 μmol photons m–2 s–1, which was the maximum irradiance used in this study. Blue (450 nm), yellow (590 nm) and red (650 nm) light had different effects on the growth of C. polykrikoides: it grew well under blue light, but not under yellow light. This implies that C. polykrikoides is more likely to cause an outbreak of red tide in the open sea where blue-green wavelengths predominate, rather than in enclosed water bodies where suspended particles absorb most of the blue wavelengths, and yellow-orange wavelengths predominate.

• 대한한방소아과학회지
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• 제25권1호
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• pp.49-62
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• 2011

Objectives: The purpose of this study is to evaluate the effect of the herbal medicine in children's growth. Methods: 67 of the children in the age from 3 to 16 were participated in this study(31 of boys and 36 of girls). Department of the pediatrics, $\bigcirc\bigcirc$ university oriental medical hospital, and the participants were measured their body composition and their bone age, the height percentile of the first and the last visit were measured, and those were compared by the Korean Association of Pediatrics' Growth Statistics Curve. Results: 1. Generally, total children's average height and weight were significantly increased after the herbal medical treatment. The comparison between the height and the average height, the weight and the average weight were significantly decreased after the herbal medical treatment. 2. Total children's average soft lean mass, body fat mass, BMI, basal metabolic rate, abdominal circumference and hip circumference were also significantly increased after the herbal medical treatment. 3. The mean height percentile of the children showed 0.88 percentile upwardly. The mean weight percentile of children showed 1.84 percentile upwardly. 4. The height percentile was increased in the group of boys younger than 13, and a group of girls older than 12 year old. Other than a group of boys older than 14, every group showed increasing weight percentile. Conclusions: The herbal medical treatment helped children with growth retardation.

• 한국전자파학회논문지
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• 제8권4호
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• pp.382-389
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• 1997

본 논문에서는 다결정 AlN 박막을 이용하여 800 MHz 대역의 표면탄성파 펼터를 시험제작한 연구 결과를 제시한다. 고주파 스퍼터링 방법에 의하여 실리콘 기판위에 증착시켜 X선 rocking curve의 반치폭이 $3^{\circ}$이고 박막 성장 방향으로 결정의 c축이 우선 배향된 박막을 얻었다. 임펄수 모텔링 기법을 이용하여 시험제작된 표면탄성파 필터는 중심주파수 865 MHz, 3 dB 대역폭 45 MHz이며 측정된 주파수 응답곡선으로부터 유도된 전기기계 결합상수는 0.8 %, 표면탄성파 전달속도는 5,709 m/s이다.

• 기술혁신학회지
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• 제10권4호
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• pp.654-686
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• 2007

과학기술 수준을 정확히 측정 분석하기 위해서는 우리 기술수준과 비교대상의 위치, 그리고 해당 기술의 이론적인 상한 수준을 우선 전제해야만 한다. 그리고 각각의 기술변화 정도를 파악하는 것이 추가적으로 필요하다. 우리나라 및 비교대상에 대한 동태적 측면이 고려되어 현재의 위치와 함께 과정과 경로도 중요시 되어야 한다. 이를 위해서 이 연구는 기술발전 단계와 성장곡선 개념을 활용하는 방안을 제시한다. 이론적 및 가상적 사례 적용 결과, 우리나라 기술수준의 향상은 뚜렷하게 보이고 있으나 같은 기간에 지속적으로 변화하고 있는 세계최고기술 수준과는 여전히 격차가 존재하는 것으로 추정된다. 추정 결과가 사실이라고 가정할 경우, 우리나라 기술의 실질적인 추격의 가능성은 그리 크지 않은 것으로 보인다. 특히, 바이오신약 장기 분야와 지능형로봇 분야의 경우에는 세계최고기술 수준과의 격차기간이 더욱 벌어지고 있는 것으로 추정되어 해당 분야에 대한 실질적이고, 심층적인 검토 및 분석이 시급히 요구된다. 이 연구는 기술수준 측정과 분석을 성장곡선 유형의 추정을 통해 위상분석과 변화과정을 파악하여 궁극적인 추격의 가능성을 제시한다. 이론적 타당성과 현실적 적용성에 대한 검증을 위해 향후 구체적인 사례분석이 필요하다.

• 한국작물학회지
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• 제44권1호
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• pp.55-58
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• 1999

Plant water status during growth is directly and indirectly associated with seed yield. The objective of the present study was to determine the genotypic differences in leaf water characteristics at an early growth stage of soybean [Glycine max (L.) Merrill] plants through the pressure-bomb technique. Measurements of water potential as well as relative water content (RWC) were made at the third leaf from the fully-expanded top leaf of eight different soybean genotypes grown for 31 to 35 days after field emergence. On the basis of the modified exponential model, pressure-volume (PV) curves were fitted well ($R^2$=0.92＊＊ to 0.99＊＊ for the curvi-linear region and R=0.67＊＊ to 0.96＊＊ for the linear region), indicating that a segmented model using PROC NLIN of SAS could be used effectively to estimate the leaf water characteristics. The regression analysis for the pressure-volume (PV) curve revealed genotypic variation in the solute potential at saturation (Ψ$_{s,sat}$ :-10.7 to -14.8 bar), solute potential at incipient plasmolysis (Ψ$_{s,ip}$ : -14.3 to -18.3 bar), RWC at incipient plasmolysis (RW $C_{ip}$ : 83.3 to 91.7%), high integrated turgor pressure from saturation to plasmolysis ( $_1$$^{b}$ : 0.39 to 0.81), and maximum volumetric modulus of elasticity ($\varepsilon$$_{max}$ : 150 to 445 bar).).

• Journal of Microbiology and Biotechnology
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• 제8권3호
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• pp.229-236
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• 1998

6-Substituted derivatives of 1-［(2-hydroxyethoxy)methyl］-6-(phenylthio)thymine (HEPT) were synthesized by introducing alkyl groups with the aid of chlorotrimethylsilane, and then purified ranging 40 to 81 % of yield. Because of their peculiar structures, we presumed that HEPT derivatives would contain extra biological activities other than their already known anti-human immunodeficiency viral (HIV -1) activities. In this study, we investigated the possible effects of the HEPT derivatives on bacterial growth and found their selective antibiotic activities against gram-positive strains. We could not observe the corresponding activity from a disc-zone test, but confirmed the activity by liquid cultivation. Since the growth rate of cells was easily recovered, the antibiotic function was suggested to be bacteriostatic. We also suggested that the intracellular fate of HEPT derivatives would be fast. A HEPT derivative f-3 was shown to synergize unidirectionally toward chloramphenicol (Chr). With 0.1 mM f-3, the Chr-directed growth-inhibitory curve appeared 4 hours earlier than found without the additive. Interestingly, from the data of SDS-polyacrylamide gel electrophoresis (PAGE), we found that a membrane-bound protein having a molecular weight of 70-kDa was overexpressed by f-3 in S. aureus.

• 대한금속재료학회지
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• 제48권9호
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• pp.791-797
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• 2010

The creep crack growth rate (da/dt) of the Cr-Mo steels tested by pre-crack and the voltage (or resistance) variables were related into fracture parameter (Ct), crack growth coefficient (H), and an exponent (q) in the parts of Base, weld and HAZ. The fracture parameter (Ct) has various variables relating to the specimen and crack shape, applied stress, and creep strain curve. The H and q was inferred by OLS regression (ordinary least square method), and the H values were solved in statistics and probability assessment, which were attained fromPDF's distributions (probability density function). The HAZ part has the highest value of q by OLS regression and the widest distribution of H by PDF of WEIBULL, which means that the crack sensitivity of HAZ should be cautioned against the creep crack growth and failure.