• Journal of Breast Disease
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• v.6 no.2
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• pp.52-59
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• 2018

Purpose: This study aimed to determine whether clinicopathological factors are potentially associated with successful breast-conserving surgery (BCS) after neoadjuvant chemotherapy (NAC) and develop a nomogram for predicting successful BCS candidates, focusing on those who are diagnosed with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative tumors during the pre-NAC period. Methods: The training cohort included 239 patients with an HR-positive, HER2-negative tumor (${\geq}3cm$), and all of these patients had received NAC. Patients were excluded if they met any of the following criteria: diffuse, suspicious, malignant microcalcification (extent >4 cm); multicentric or multifocal breast cancer; inflammatory breast cancer; distant metastases at the time of diagnosis; excisional biopsy prior to NAC; and bilateral breast cancer. Multivariate logistic regression analysis was conducted to evaluate the possible predictors of BCS eligibility after NAC, and the regression model was used to develop the predicting nomogram. This nomogram was built using the training cohort (n=239) and was later validated with an independent validation cohort (n=123). Results: Small tumor size (p<0.001) at initial diagnosis, long distance from the nipple (p=0.002), high body mass index (p=0.001), and weak positivity for progesterone receptor (p=0.037) were found to be four independent predictors of an increased probability of BCS after NAC; further, these variables were used as covariates in developing the nomogram. For the training and validation cohorts, the areas under the receiver operating characteristic curve were 0.833 and 0.786, respectively; these values demonstrate the potential predictive power of this nomogram. Conclusion: This study established a new nomogram to predict successful BCS in patients with HR-positive, HER2-negative breast cancer. Given that chemotherapy is an option with unreliable outcomes for this subtype, this nomogram may be used to select patients for NAC followed by successful BCS.

• Korean Journal of Breeding Science
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• v.41 no.4
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• pp.451-455
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• 2009

Lilium lancifolium, which is one of the Korean native lilies, possesses several useful genetic characteristics such as growth vigor, bulbil formation and resistance to Fusarium. Hybridization was performed to insert useful traits of Asiatic hybrid "Dreamland" as the male parent with upward direction and dark brown spotless on the petal into L. lancifolium as the female parent. The rate of pollen germination of L. lancifolium and "Dreamland" were 30% and 60%, respectively. The pollen germination ratio of $F_1$ progenies at flowering date was 25-57%, which is between the parents'pollen germination ratio. The individual flowering time was between 113 days and 131 days after planting. Of 99% of all plants, the leaf shape index was more than five, which means that the leaf shape of $F_1$ plants is more influenced by female than male parent. The flower color was separated into four types. 51.5% of the progenies showed orange and 44.2% showed light orange, respectively. The colors seemed to be highly influenced by female parents. Mixed colors of parents, orange yellow and light yellow orange, were 3.1%, 1.2%, respectively. Flowering directions were segregated by three different ways, upside, side, and downside. Side direction, which is medium type between female and male parent, was 73%. All progenies showed lots of spot on petals except one offspring. The percentage of bulbil formation on leaf axil was 49.4%. Among those, the maximum number of bulbil formation was 25. The mean number of bulbil formation per plant was five.

• Journal of Climate Change Research
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• v.8 no.4
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• pp.415-424
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• 2017

This study was conducted to estimate carbon stocks of Pinus densiflora with drawing volume of trees in each tree height and DBH applying the suitable stem taper equation and tree specific carbon emission factors, using collected growth data from all over the country. Information on distribution area, tree age, tree number per hectare, tree volume and volume stocks were obtained from the $5^{th}$ National Forest Inventory (2006~2010) and Statistical yearbook of forest (2016), and method provided in IPCC GPG was applied to estimate carbon stock and uptake. Performance in predicting stem diameter at a specific point along a stem in Pinus densiflora by applying Kozak's model, $d=a_{1}DBH^{a_2}a_3^{DBH}X^{b_{1}Z^2+b_2ln(Z+0.001)+b_3\sqrt{Z}+b_4e^z+b_5(\frac{DBH}{H})}$, which is well known equation in stem taper estimation, was evaluated with validations statistics, Fitness Index, Bias and Standard Error of Bias. Consequently, Kozak's model turned out to be suitable in all validations statistics. Stem volume table of P. densiflora was derived by applying Kozak's model and carbon stock tables in each tree height and DBH were developed with country-specific carbon emission factors ($WD=0.445t/m^3$, BEF = 1.445, R = 0.255) of P. densiflora. As the results of analysis in carbon uptake for each province, the values were high with Gangwon-do $9.4tCO_2/ha/yr$, Gyeongsandnam-do and Gyeonggi-do $8.7tCO_2/ha/yr$, Chungcheongnam-do $7.9tCO_2/ha/yr$ and Gyeongsangbuk-do $7.8tCO_2/ha/yr$ in order, and Jeju-do was the lowest with $6.8tC/ha/yr$. Total carbon stocks of P. densiflora were 127,677 thousands tC which is 25.5% compared with total percentage of forest and carbon stock per hectare (ha) was $84.5tC/ha/yr$ and $7.8tCO_2/ha/yr$, respectively.

• International Area Studies Review
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• v.20 no.2
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• pp.3-23
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• 2016

In this study, we used actual proof analysis, based on SVAR model according to economy theory, to observe the impact of actual and financial market of Korea, Japan, and China that have adopted quantitative easing export based strategy of growth, an unconventional monetary policy of the U.S. As a result of estimation, it appears that real effective exchange rate rise shock of Korea, Japan, and China against U.S. dollar has a negative influence on current account and index of industrial product, which are real economy. It can be implied that the result is driven from the fact that strong home currency of Korea, Japan, and China decreases price competitiveness of exports, causing negative influence on real economy. The real effective exchange rate shock against U.S. dollar appeared to decrease national bond rate of Korea and Japan, while increasing that of China. In instances of Korea and Japan, it is implied that national bond rate decreases as foreigner investment funds flow in, considering foreign-exchange profit through advanced financial market with high opening extent. On the other hand, because there are strong regulation on opening extent of Chinese financial markets, the influence seems to be greater for domestic policy, rather than a foreign influence. Lastly, Korea showed a more dramatic variable reaction to exchange rate shock compared to Japan or China. It is implied from the result that Korea is relatively more susceptible and fragile in regards of international status of economic size and currency.

• Journal of The Korean Society of Integrative Medicine
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• v.6 no.4
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• pp.171-182
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• 2018

Purpose : The purpose of this study was to examine the relationship between the characteristics of caregivers and adults with intellectual disability, and social support, family function, and rehabilitation needs in caregivers. Methods : A total 98 pairs of adults with intellectual disability and their caregivers participated in this study. The researchers examined the general characteristics of the adults with intellectual disability and their caregivers. The evaluation included analysis of the level of activities of daily living, ability to communicate, and health status of the adults with intellectual disability, while the family income, health status, utility and the need for rehabilitation, social support (multidimensional scaled perceived social support, MSPSS) and family function (adaptation, partnership, growth, affection, resolve, and APGAR index) of the caregivers were measured. The data collected were analyzed to determine the relationship of the characteristics of adults with intellectual disability and the social support, family function, and rehabilitation needs of caregivers using regression and correlation analysis. Results : The rehabilitation needs were significantly correlated with the age of the adults with intellectual disability (p<.01), and the subjective health status of the caregivers (p<.05). The education level of the caregivers affected social support significantly ($R^2=.058$, p=.021). The communication ability of the adults with intellectual disability affected family function ($R^2=.071$, p=.01). The social support of caregivers had a significant effect on family function ($R^2=.488$, p<.001). Conclusion : These findings suggest that the barriers to community rehabilitation should be lowered, and the authors discussed the results of the present investigation.

• Journal of Korea Technology Innovation Society
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• v.21 no.4
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• pp.1577-1605
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• 2018

This study analyzes China's technology billionaires. However, this study does not show the accumulating process of wealth in each of the Chinese billionaires, because there are many technology billionaires, but only deals with the macro analysis of the technology billionaire; the pattern of existence, comparison with other industries, the process of wealth creation reflecting China's particularity, and comparison with the world's technology billionaires. The findings of this study are as follows. First, more than 10 billion yuan of Chinese billionaires will emerge from 2004. Second, in the early days, illegal and corruption made rich, but the wealth of own efforts has gradually increased. Third, the real estate and manufacturing billionaires are still strong overall, but the growth of billionaires in technology, medicine and finance industry is remarkable. Fourth, in the case of the top 10 richest, four are from real estate, four from technology, and two from manufacturing and distribution. Most technology billionaires are in Guangdong, Zhejiang, Beijing and Shanghai. The determinants of the number of billionaires are GDP, exchange rate to US Dollar and Shenzen Stock Index, and those of technology billionaire are GDP and exchange rate. Given the relationship with existing theories, this study can be called the fifth type of billionaire research. Conceptually, the main reason for accumulating wealth is the search for policy opportunities, market opportunities and technology opportunities.

• Journal of the Korea Organic Resources Recycling Association
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• v.27 no.3
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• pp.15-25
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• 2019

The study was conducted to compare the chemical properties and microbial activity of soil and the crop productivity by applying homemade liquid fertilizers (LF) used in leading cucumber farms as well as to evaluate the eco-friendly LFs to substitute for a chemical fertilizer. Three homemade LFs, EM, starfish, and native microbes, and a chemical LF were regularly fertigated per three days during the growing season. Chemical LF contained the highest pH, EC (electrical conductivity), and concentrations of T-N, $P_2O_5$, K, Ca, and Mg, while the lowest EC level was observed for EM LF. Soil EC was the highest to the 3.0 dS/m for chemical LF-plots, with lowering soil pH, OM (organic matter), and Mg concentration. Soil chemical properties mostly increased in native microbes LF-plots. However, soil microbial properties were not significantly different among the LF treatment plots. OTU (operational taxonomic units), richness estimator, and diversity index of bacteria and fungi increased in the chemical LF and EM LF based on the pyrosequencing analysis. SPAD and PS II values on the treated-cucumber leaves were seasonally decreased from 32 to 60 days after transplanting, with the rapid decline observed at 45 days after transplanting. Number of leaves and crop height increased in the treatments with EM and native microbes LF. LF treated-cucumber crops were not significantly different for total fresh weight and fruit yield.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.352-362
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• 2019

The study investigates one of the long-standing, but still controversial issues in modern finance from the international and domestic perspectives. That is, financial components and differences on corporate profitability are identified and compared under the primary hypotheses. Empirical research settings include the sample data as KOSPI-listed chaebol firms, time reference covering the post-era of the global financial turmoil and two differently defined profitability indices measured by the market- and the book-value bases. A majority of total 7 explanatory variables except firm size and leverage ratio reveal their statistically significant power to explain profitability indices for the chaebol firms in the first hypothesis. The results are generally compatible with those obtained from their counterparts of non-chaebol firms. In the second hypothesis applying multinomial logistic model, the chaebol firms are classified into three groups according to the level of profitability. It is then confirmed that variables to represent the market-valued debt ratio, business risk and growth potential are financially discriminating factors among the three groups. The study may provide a new vision to identify financial factors of corporate profitability for Korean chaebol firms after the global financial crisis, which can enhance the benefits of interested parties at the government or corporate level in a virtuous cycle.

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.1
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• pp.10-20
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• 2019

Individual dental age is used as an index of chronological age estimation and is an important indicator of the child's growth stage. Dental age does change greatly over time, but it changes constantly. And updating information about this change is important. The purpose of this study was to provide information about tooth eruption stage using diagnostic model analysis and to investigate tooth eruption sequence and estimate chronological age based on this information. Tooth eruption stages were measured on a diagnostic model from 488 patients in 5 - 13 year old children. Based on the information on eruption stage, eruption sequence in maxilla was first permanent molar, central incisor, lateral incisor, first premolar, canine, second premolar and second permanent molar. Eruption sequence in mandible was first permanent molar, central incisor, lateral incisor, canine, first premolar, second premolar and second permanent molar. There were significant differences between males and females in the eruption stage of canine, first and second premolar, and second molar at several ages. The chronological age of male and female was estimated by the coefficient of determination of 0.816, 0.826 respectively.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.661-670
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• 2021

Research trends can be usefully used to determine the importance of research topics by period, identify insufficient research fields, and discover new fields. In this study, research trends of urban spaces, where various problems are occurring due to population concentration and urbanization, were analyzed by topic modeling. The analysis target was the abstracts of papers listed in the Korea Citation Index (KCI) published between 2002 and 2019. Topic modeling is an algorithm-based text mining technique that can discover a certain pattern in the entire content, and it is easy to cluster. In this study, the frequency of keywords, trends by year, topic derivation, cluster by topic, and trend by topic type were analyzed. Research in urban regeneration is increasing continuously, and it was analyzed as a field where detailed topics could be expanded in the future. Furthermore, urban regeneration is now becoming a regular research field. On the other hand, topics related to development/growth and energy/environment have entered a stagnation period. This study is meaningful because the correlation and trends between keywords were analyzed using topic modeling targeting all domestic urban studies.