• Title/Summary/Keyword: Growth Effect

Search Result 17,891, Processing Time 0.061 seconds

Effect of CP-2 Extracted from Coptis and Croton tiglium L. on the Growth and Steroidgenesis of Follicular Granulosa Cells (콥티스속 근경과 탈지된 클로톤 종자의 혼합 추출물(CP-2)이 난포 Granulosa Cell에 미치는 영향)

  • 김종배;김종배;문정조;한영복;김종배
    • Korean Journal of Animal Reproduction
    • /
    • v.17 no.1
    • /
    • pp.13-19
    • /
    • 1993
  • We investigated the effects of CP-2 extracted from the mixture of Copis and Croton tiglium L, which showed very high cytotoxic effect to the various tumor cells, on the growth and steroidenesis of primary and transformed cell lines PA-GS6 and PO-GRS1 by cotransfectionwith SV40 and Ha ras oncogenes. CP-2 inhibited the growth of PA-GS6 and PO-GRS1 in a dose dependent manner when the growth of them was measured by cell number and by protein content, while CP-2 did not affect the growth of primary granulose cells. Productions of progesterone ofprimary and transformed granulosa cells were stimulated by forskolin, but this stimulatory effect was blocked by treatment of CP-2. Clinical application of CP-2 asa new anti-cancer drug and utilization of transformed granulosa cells as a model system for the screening of anti-cancer drug were also discussed.

  • PDF

High-Skilled Inventor Emigration as a Moderator for Increased Innovativeness and Growth in Sending Countries

  • Kim, Jisong;Lee, Nah Youn
    • East Asian Economic Review
    • /
    • v.23 no.1
    • /
    • pp.3-26
    • /
    • 2019
  • This study investigates the effect of high-skilled inventor emigration rate on growth rate of the country of origin (COO). Inventor emigrants represent the human capital that can generate highly innovative work. The social network they form spurs knowledge diffusion and technology transfer back to their COOs, which in turn affects innovation and growth in their home countries. We run dynamic panel estimation for 154 countries during 1990-2011, and empirically show that a positive and statistically significant effect exists for the interaction of inventor emigration and trade. The result indicates that the direct negative impact of the brain drain can be mitigated by the positive feedback effect generated by the high-skilled inventor emigrants abroad. When coupled with an active trade policy that reinforces growth, countries can partially recoup the direct effect of the human capital loss. We stress the importance of international trade for successful technology transfer to occur, and offer insights for policies that can utilize the benefits of the rich social network of their high-skilled emigrants.

The effect of Anemarrhena asphodeloides ethanolic extracts on hair growth effect in mice (지모(知母) 에탄올 추출물이 쥐의 모발 성장에 미치는 영향)

  • Park, Jang-Soon
    • Journal of the Korea Convergence Society
    • /
    • v.9 no.8
    • /
    • pp.219-224
    • /
    • 2018
  • We have studied anemarrhena asphodeloides, a hair growth promoter as an alternative medicine agent to compensate for the disadvantages of minoxidil, which has excellent hair growth promoting effect on follicular epithelial cells. anemarrhena asphodeloide, an Rhizome plant of aemarrhena asphodeloide family, is a traditional medicinal plant used in Korea as an antipyretic, antidiabetic, antidepressant, antiinflammatory. We applied and observed anemarrhena asphodeloides ethanol extracts to the back of mice, and there was no significant difference in body weight and food intake among all groups of mice. The ethanol extract of anemarrhena asphodeloides showed vigorous hair growth promoting effect without changing the serum composition and thus it is considered to be useful as a hair growth promoter in the future.

Effect of Graphite on Rice Growth (흑연(GRAPHITE)의 벼 생육에 미치는 영향)

  • Hwang, Cher-Won
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.36 no.2
    • /
    • pp.86-91
    • /
    • 2003
  • Carbon material such as graphite and activated charcoal can promote the growth of some formsog bacteria. We examined whether this bacterial growth promoting effect can have a positive influence on field crops. Refined graphite was mixed into the standard soil used in rice cultivation. Varying soil graphite mixtures of 0.1%, 0.5% and 1% were used to cultivate rice seedling for 3 weeks. After transplanting in the filed, rice plants were cultivated for 4 months. To observe the effect of graphite(carbon material) during the cultivation of rice, we examined various different growth components in this research. During the transplanting stage, growth promoting effect of carbon was observed in the 0.1% carbon added soil. However, there were not much difference between graphite added soil and standard soil in the other stages. Rice yield was highest in the soil with 0.1% graphite.

The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion (찔레뿌리 추출물을 주성분으로 하는 천연물 조성물의 발모촉진 효과에 관한 전임상 및 임상시험 연구)

  • Kim, Joong-Hark;Hong, Sung-Kil;Hwang, Sung-Jue;Son, Sang-Wook;Choi, Yong-Soon
    • Korean Journal of Medicinal Crop Science
    • /
    • v.20 no.2
    • /
    • pp.108-116
    • /
    • 2012
  • In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing $Rosa$ $mutiflora$ roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP ($125.0{\pm}4.9\;FU/cm^2$) compared to before treatment ($104.3{\pm}4.7\;FU/cm^2$, p < 0.05), and hair thickness were also significantly increased ($0.066{\pm}0.003$ mm) than before treatment ($0.055{\pm}0.002$ mm, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with $1.23{\pm}0.05$ (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

A Study on the Morpholgies and Mechanical Properties of Sn-Zn Eutectic Alloys (Sn-Zn 공정합금(共晶合金)의 응고속도(凝固速度)에 따른 조직(組織)과 기계적(機械的) 성질(性質)에 관한 연구(硏究))

  • Lee, J.H.;Lee, K.W.
    • Journal of Korea Foundry Society
    • /
    • v.5 no.4
    • /
    • pp.258-270
    • /
    • 1985
  • The structures and mechanical properties of undirectionally solidified Sn-Zn eutectic alloys have been examined over the growth range 7mm/h to 6,000mm/h. The structures of unidirectionally solidified Sn-Zn eutectic alloys were primarily broken-lamellar at growth rates below 760mm/h and became fibrous at higher growth rates above that. At a growth rate 3,084mm/h the structures were fibrouse only. There is no dendrites at any growth rates, but occasionally ribbon-like morphologies were seen. The under cooling increased parabolically with growth rate increase. The hardness of specimes increased with growth rates increase but heat-treated specimen decreased after growth rates 760mm/h and became constant value. The effect of heat-treatment was good at lower growth rate. At room temperature tensile strength increased with growth rates up to R=990mm/h and then tensile strength became near-constant value. The effect of heat-treatment was well at lower growth rate.

  • PDF

Market Access Approach to Urban Growth

  • MOON, YOON SANG
    • KDI Journal of Economic Policy
    • /
    • v.42 no.3
    • /
    • pp.1-32
    • /
    • 2020
  • This paper studies urban growth in Korean cities. First, I document that population growth patterns change over time and that the current population distribution supports random urban growth. I confirm two empirical laws-Zipf's law and Gibrat's law-both of which hold in the period of 1995-2015, but do not hold in the earlier period of 1975-1995. Second, I find a systematic employment growth pattern of Korean cities in spite of the random population growth. I examine market access effects on employment growth. Market access, a geographical advantage, has a significant influence on urban employment growth. The market access effect is higher in the Seoul metropolitan area than in the rest of the country. This effect is stronger on employment growth in the manufacturing industry compared to employment growth in the service industry. These results are robust with various checks (e.g., different definitions of urban areas). The results here suggest that policymakers should consider geographical characteristics when they make policy decisions with respect to regional development.

Growth Mechanism Evolution of ZnO Nanostructures by Leidenfrost Effect in Ultrasonic Spray Pyrolysis Deposition (초음파 분무 열분해법에 의한 ZnO 나노구조 성장시 Leidenfrost 효과에 의한 성장 거동 변화)

  • Han, In Sub;Park, Il-Kyu
    • Korean Journal of Materials Research
    • /
    • v.27 no.11
    • /
    • pp.609-616
    • /
    • 2017
  • We investigated a Leidenfrost effect in the growth of ZnO nanostructures on silicon substrates by ultrasonic-assisted spray pyrolysis deposition(SPD). Structural and optical properties of the ZnO nanostructures grown by varying the growth parameters, such as substrate temperature, source concentration, and suction rate of the mist in the chambers, were investigated using field-emission scanning electron microscopy, X-ray diffraction, and photoluminescence spectrum analysis. Structural investigations of the ZnO nanostructures showed abnormal evolution of the morphologies with variation of the substrate temperatures. The shape of the ZnO nanostructures transformed from nanoplate, nanorod, nanopencil, and nanoprism shapes with increasing of the substrate temperature from 250 to $450^{\circ}C$; these shapes were significantly different from those seen for the conventional growth mechanisms in SPD. The observed growth behavior showed that a Leidenfrost effect dominantly affected the growth mechanism of the ZnO nanostructures.

A Study on the Effect of a Single Overload on Fatigue Crack Retardation (단일과대하중이 피로균열성장에 미치는 영향에 관한 연구)

  • Kim, Kyung-Su;Kim, Sung-Cahn;Shin, Chun-Sik;Park, Jin-Young;Lee, Chang-Hwan
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
    • /
    • 2002.10a
    • /
    • pp.73-78
    • /
    • 2002
  • Ships and ocean structures are generally under random loading. Various type of variable-amplitude loading affects fatigue crack growth and fatigue life. However interaction effects due to irregularity of loading including random loading have not explained exactly and it is difficult to examined fatigue crack growth behaviour and fatigue life for this reason. Therefore in this paper crack growth tests with constant-amplitude loading including a single overload were conducted to measure plastic zone size near crack tip of DENT specimen. And the observed plastic zone sized were discussed in terms of crack growth rate. As a result of this the effect the plastic rue size due to the overload is examined on the effect on crack growth rate and, consequently, fatigue life.

  • PDF

Effect of Growth Retardants on the Growth of Periila fuetescens var. acuta (차즈기(Perilla frutescens var. acuta)의 생육에 미치는 생장억제제의 영향)

  • Lee, Jong-Suk;Park, Young-Min
    • Journal of the Korean Society of Environmental Restoration Technology
    • /
    • v.7 no.2
    • /
    • pp.1-11
    • /
    • 2004
  • The purpose of this study was to determine usability as potted flowers and garden plants by controlled plant height using growth retardants. There was no significant difference on the dwarfing effect according to the degree of exposure the sun, but growth was well under full exposure to the sun. The plant height was decreased by application of Cycocel (CCC), Bonzi (paclobutrzol), Ancymidol, and Uniconazole compared to the control group, and treatment of Bonzi $5mg{\cdot}L^{-1}$ was most dwarfing effect for both full sun exposure or 70% controlled shading condition. No consistent different was found in stem diameter, leaf color change, the content of chlorophyll and anthocyanin when the concentration of plant growth retardants was altered. These factors were affected only by light intensity. In comparison to the results of the control group, leaf length, leaf width, plant width and petiole length were all reduced by the application of growth retardants.