• Korean Journal of Health Education and Promotion
• /
• v.14 no.2
• /
• pp.125-147
• /
• 1997

This study was conducted in order to identify the extent to which Health Belief Model (HBM) constructs explain the likelihood of taking preventive behaviors for AIDS among the young adolescents in Korea. HBM was applied as the theoretical framework for developing questionnaire items in this study. The survey instrument included all of the constructs of Health Belief Model, namely, perceived susceptibility, perceived severity, perceived benefit, perceived barriers, cue to actions for preventive behaviors concerning AIDS. Additionally, demographic characteristics of the respondents, their sexual experiences, and AIDS Knowledge Test were included in the study. Each of HBM constructs were developed with a 5-point Likert type scale from l(never agree) to 5 (absolutely agree). The survey was conducted with a total of 247 military men in a city on September 18, 1996, using self-reported questionnaire. The results of the study were summarized as follows: 1. Because the subjects for this study were military soldiers, their demographic characteristics were limited to all men, young age, and ummarried. Educational status was evenly distributed between high school graduates and university students. 2. On the average, the respondents started their first sexual relationship at 18 years old and 82.6% of them did not use condom when having their first sexual experience. Thirty-one percent of the subjects had sexual contact with prostitutes and the average number of sexual contact with prostitutes was 5 times during the past 2 years. 3. The results of AIDS Knowledge Test scores demonstrated that the respondents had a high level of knowledge about AIDS. However, some misconceptions about transmission of AIDS through casual contact were still prevailed. Sixty-six percent of the respondents expressed that people infected with HIV should be isolated from the society in order to protect the general public. 4. All the respondents expressed that they had heard about AIDS before. TV was found to be the source which provided information on AIDS most frequently. 5. Among fundamental constructs of Health Belief Model, scores of perceived benefit of taking preventive action against AIDS marked the highest score, while scores of perceived susceptibility were the lowest. As a result of Multiple Stepwise Regression analysis, 13 variable groups were found to predict the preventive action by 25%. Among them, only perceived benefit variables was the most significant factor to explain preventive behaviors by 17%.

• Journal of Korean Medicine for Obesity Research
• /
• v.15 no.2
• /
• pp.104-110
• /
• 2015

Objectives: The herb of Agastache rugosa (AR) is a traditional herbal medicine used for colds, vomiting and furuncles. However, there are few reports to investigate the inhibitory effects of AR on obesity. In this study, the effects of AR on high fat diet (HFD)-induced obesity and its mechanism of actions were investigated in experimental animals. Methods: The mice were fed HFD for 4 weeks to induce obesity. After randomly divided into normal fat diet, HFD and AR groups, 200 mg/kg of AR was administrated for 4 weeks with continuous HFD feeding while vehicle was orally treated to HFD group. Food intake and body weight were recorded weekly. Results: Increased body weight by HFD was improved by AR treatment. AR administration inhibited an increase of visceral fat weight as well as adipocyte hypertrophy. Hepatic steatosis was ameliorated in AR-treated mice. In addition, treatment of AR attenuated the expression of adipogenic transcription factor, peroxisome proliferator-activated receptor (PPAR)-gamma in the epididymal adipose tissue. Also the increased serum leptin level by HFD was maintained in AR group, leading to inhibition of food intake. Conclusions: AR treatment showed inhibitory effects on HFD-induced obesity by inhibition of PPAR-gamma and reduction of food intake. AR could be an alternative treatment for obesity.

• Molecules and Cells
• /
• v.19 no.3
• /
• pp.356-364
• /
• 2005

Intramolecular excimer formation of 1,3-di(1-pyrenyl) propane(Py-3-Py) and fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) were used to evaluate the effect of ethanol on the rate and range of lateral and rotational mobilities of bulk bilayer structures of synaptosomal plasma membrane vesicles (SPMVs) from the bovine cerebral cortex. Ethanol increased the excimer to monomer fluorescence intensity ratio (I'/I) of Py-3-Py in the SPMVs. Selective quenching of both DPH and Py-3-Py by trinitrophenyl groups was used to examine the range of transbilayer asymmetric rotational mobility and the rate and range of transbilayer asymmetric lateral mobility of SPMVs. Ethanol increased the rotational and lateral mobility of the outer monolayer more than of the inner one. Thus ethanol has a selective fluidizing effect within the transbilayer domains of the SPMVs. Radiationless energy transfer from the tryptophans of membrane proteins to Py-3-Py was used to examine both the effect of ethanol on annular lipid fluidity and protein distribution in the SPMVs. Ethanol increased annular lipid fluidity and also caused membrane proteins to cluster. These effects on neuronal membranes may be responsible for some, though not all, of the general anesthetic actions of ethanol.

• Journal of the Korea Society of Computer and Information
• /
• v.21 no.6
• /
• pp.89-96
• /
• 2016

Damage and attack size of cyber terror is growing to the national size. Not only targeting at a certain companies or individuals but number of cyber terror targeting government bodies or unspecific people is increasing. This is because compared to traditional weapon, input cost is very cheap but ripple effect and shock are much stronger, affecting not only certain groups but also each individuals. 'Anti-terror measurement for protection of nation and public safety' passed last month is one of the renowned measurement passed regardless of objection from opposition party. The opposition party went against this through filibuster for 192 hours but this finally passed National Congress due to lack of oppositions. Korean government is taking post actions after passage of anti-terror measurement. Legislation of enforcement ordinance and regulations is due by 6th of next month. This regulation will be executed from June 4th after legislation. Whenever there is any security issues such as hacking of Korea Hydro and Nuclear Power and National Intelligence Service happens, lot of attention is made to those hackers. However, social recognition or management of those hackers need lot more improvement. Especially, as market of internet of things is increasing, there is an increased anxiety on information security. But as we only rely on security solutions, this problems are keep happening. Therefore, active investment on nurturing hackers who play the role of 'spear and shield' shall be made. Government should put more efforts to allow white hackers to show their abilities. We should have a policy for supporting high-quality programs such as BoB. To make information protection industry into future growth engine, it is necessary to nurture professionals for information protection and white hackers through special programs. Politicians should make related regulations as soon as possible to remove factors that prevent swift management of cyber attack due to lack of legislation. Government should pay lot more financial investment to nurturing professional manpower than now. Protecting life and asset of nation is responsibility and duty of our government. We all should recognize that controlling cyber attack is a part of national defense.

• Archives of Pharmacal Research
• /
• v.28 no.7
• /
• pp.839-847
• /
• 2005

The aim of this study was to provide the basis to further examine the mode of action of ethanol. Fluorescent probes reported to have different membrane mobilities were used to evaluate the effect of dimyristoylphosphatidylethanol (DMPEt) on the lateral and rotational mobilities of liposome lipid bilayers. An experimental procedure, based on the selective quenching of 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane (Py-3-Py) by trinitrophenyl groups, was used. DMPEt increased the bulk lateral and rotational mobilities, and had a greater fluidizing effect on the outer than the inner monolayer. These effects of DMPEt on liposomes may be responsible for some, but not all, of the general anesthetic actions of ethanol.

• Journal of the Korean Data and Information Science Society
• /
• v.23 no.3
• /
• pp.559-568
• /
• 2012

This paper deals with the relations between the quality of life and the life satisfaction of the elderly based on the 2008 national survey data of the actual living condition of the elderly and welfare need. We found that the questions about the quality of life is categorized by three groups such as self consolidation, harmony between generations and hope for later activity, which is the order of the power of the affection to life satisfaction. The result of this paper could be used as a basic document for taking efficient actions for the welfare services to the elderly.

• Restorative Dentistry and Endodontics
• /
• v.45 no.3
• /
• pp.31.1-31.20
• /
• 2020

Matrix metalloproteinases (MMPs) are enzymes that can degrade collagen in hybrid layer and reduce the longevity of adhesive restorations. As scientific understanding of the MMPs has advanced, useful strategies focusing on preventing these enzymes' actions by MMP inhibitors have quickly developed in many medical fields. However, in restorative dentistry, it is still not well established. This paper is an overview of the strategies to inhibit MMPs that can achieve a long-lasting material-tooth adhesion. Literature search was performed comprehensively using the electronic databases: PubMed, ScienceDirect and Scopus including articles from May 2007 to December 2019 and the main search terms were "matrix metalloproteinases", "collagen", and "dentin" and "hybrid layer". MMPs typical structure consists of several distinct domains. MMP inhibitors can be divided into 2 main groups: synthetic (synthetic-peptides, non-peptide molecules and compounds, tetracyclines, metallic ions, and others) and natural bioactive inhibitors mainly flavonoids. Selective inhibitors of MMPs promise to be the future for specific targeting of preventing dentin proteolysis. The knowledge about MMPs functionality should be considered to synthesize drugs capable to efficiently and selectively block MMPs chemical routes targeting their inactivation in order to overcome the current limitations of the therapeutic use of MMPs inhibitors, i.e., easy clinical application and long-lasting effect.

• The KIPS Transactions:PartC
• /
• v.10C no.6
• /
• pp.665-674
• /
• 2003

In this paper, we propose an approach to correlate alerts using a clustering analysis of data mining techniques in order to support intrusion detection system. Intrusion detection techniques are still far from perfect. Current intrusion detection systems cannot fully detect novel attacks. However, intrucsion detection techniques are still far from perfect. Current intrusion detection systems cannot fully detect novel attacks or variations of known attacks without generating a large amount of false alerts. In addition, all the current intrusion detection systems focus on low-level attacks or anomalies. Consequently, the intrusion detection systems to underatand the intrusion behind the alerts and take appropriate actions. The clustering analysis groups data objects into clusters such that objects belonging to the same cluster are similar, while those belonging to different ones are dissimilar. As using clustering technique, we can analyze alert data efficiently and extract high-level knowledgy about attacks. Namely, it is possible to classify new type of alert as well as existed. And it helps to understand logical steps and strategies behind series of attacks using sequences of clusters, and can potentially be applied to predict attacks in progress.

• Journal of Nutrition and Health
• /
• v.45 no.5
• /
• pp.462-469
• /
• 2012

We investigated dietary effects of prickly pear cactus (Opuntina ficus-indica) on plasma lipids, platelet aggregation (PA), hemolysis, plasma TBARS and liver enzymes. Twenty eight volunteer diving women in Jeju island had daily 20 g cactus tea containing 27% prickly pear cactus (PPC) powder for 4 weeks, and data for the study subjects were analyzed, on the basis of diagnostic criteria for blood pressure (BP)(${\geq}$ 140/90 mmHg), plasma cholesterol (${\geq}$ 200 mg/dL) and triglyceride (${\geq}$ 150 mg/dL). The subjects with higher BP had higher plasma total cholesterol (TC) and triglyceride (TG) concentrations than those with normal BP. Those with higher TC also had higher TG. Subjects with normal BP or normal TC had higher initial slope of PA than their higher counterpart in BP and TC. PPC intake decreased plasma TG in those with higher BP. PPC intake significantly decreased the elevated initial slope in groups with normal BP, TC, and TG. Hemolysis after PPC intake decreased significantly in all the subjects and plasma TBARS decreased in the subjects with higher plasma TC and higher TG. Glutamic-oxaloacetic transaminase (GOT) significantly increased and total bilirubin significantly decreased in all the subjects after PPC intake. The present study with diving women showed that beneficial effects of short term intake of prickly pear cactus might differ depending on the subject conditions in term of blood pressure, and plasma lipids. However, long term usage of prickly pear cactus may provide preventive effects of cardiovascular diseases to all the population, presumably by hypolipidemic, antithrombotic, and antioxidant actions of its bioactive flavonoids and soluble fiber.

• Korean Journal of Environmental Agriculture
• /
• v.40 no.4
• /
• pp.295-312
• /
• 2021

BACKGROUND: Global warming is one of the most pressing environmental issues which concomitantly complicates global climate change. Methane emission is a balance between methanogenesis and methane consumption, both of which are driven by microbial actions in different ecosystems producing methane, one of the major greenhouse gases. Paddy fields are major sources of anthropogenic methane emissions and could be compounded by organic fertilization. METHODS AND RESULTS: Literature reviews were conducted to give an overview of the global warming conditions and to present the relationship of carbon and methane to greenhouse gas emissions, and the need to understand the underlying processes of methane emission. A more extensive review was done from studies on methane emission in paddy fields under organic fertilization with greater emphasis on long term amendments. Changes in paddy soils due to organic fertilization include alterations of the physicochemical properties and changes in biological components. There are diverse phylogenetic groups of methanogens and methane oxidizing bacteria involved in methane emission. Also, multiple factors influence methanogenesis and methane oxidation in rice paddy fields under organic fertilization and they should be greatly considered when developing mitigating steps in methane emission in paddy fields especially under long term organic fertilization. CONCLUSION(S): This review showed that organic fertilization, particularly for long term management practices, influenced both physicochemical and biological components of the paddy fields which could ultimately affect methanogenesis, methane oxidation, and methane emission. Understanding interrelated factors affecting methane emission helps create ways to mitigate their impact on global warming and climate change.