• The Journal of Korean Medicine
• /
• v.23 no.1
• /
• pp.145-155
• /
• 2002

Objectives : Korean traditional medicinal herbs and some formulas have been used to improve the function of the hematopoietic system. The present research is to examine the effect of DanSamSaMul- Tang(DSSMT) as a biological response modifier related to hemato-potentiating function using bone marrow cell as a testing system. Methods : Mice with leukopenia and thrombocytopenia induced by CTX were treated with DSSMT Extracts. Then we observed cytokines mRNA expression level, the number of CFU-GEMM and BFU-E, and the expression of TPO and SCF in bone marrow cells of mice. Results : In the DSSMT group, the gene expressions of hematopoietic cytokines were increased significantly and the number of CFU-GEMM and BFU-E of this group was significantly increased compared to the group treated only with EPO and IL-3. The expressions of TPO and SCF in the group treated with DSSMT were higher than those of the control group. Conclusions : We showed that DSSMT has a good effect on the hematopoietic system. This could also be used as important research data for Korean oriental medicine about hemato-potentiating.

• Health Policy and Management
• /
• v.33 no.2
• /
• pp.173-184
• /
• 2023

Background: The coronavirus disease 2019 pandemic has been challenging the healthcare service, i.e., the vitalization of the point of care accompanying self-testing in vitro diagnostic medical devices (IVDs). This study aims to suggest priority criteria to classify self-testing IVDs using the analytic hierarchy process technique. Methods: Two dimensions of the characteristics embedded in the IVDs and the diseases to be diagnosed with self-testing IVDs were parallelly considered and independently investigated. In addition, three expert panels consisting of laboratory medical doctors (n=11), clinicians (n=10), and citizens (n=11) who have an interest in the selection of self-testing IVDs were asked to answer to questionnaires. Priorities were derived and compared among each expert panel. Results: First of all, ease of specimen collection (0.241), urgency of the situation (0.224), and simplicity of device operation (0.214) were found to be the most important criteria in light of the functional characteristics of self-testing IVDs. Medical doctors valued the ease of specimen collection, but the citizen's panel valued self-management of the disease more. Second, considering the characteristics of the diseases, the priority criteria were shown in the order of prevalence of diseases (0.421), fatality of disease (0.378), and disease with stigma (0.201). Third, medical doctors responded that self-testing IVDs were more than twice as suitable for non-communicable diseases as compared to communicable diseases (0.688 vs. 0.312), but the citizen's group responded that self-testing IVDs were slightly more suitable for infectious diseases (0.511 vs. 0.489). Conclusion: Our findings suggested that self-testing IVDs could be primarily classified as the items for diagnosis of non-communicable diseases for the purpose of self-management with easy specimen collection and simple operation of devices, taking into account the urgency of the situation as well as prevalence and fatality of the disease.

• Human Ecology Research
• /
• v.55 no.1
• /
• pp.13-26
• /
• 2017

This study investigated the latent groups depending on married working women's work-family spillover. The effects of factors that determine mental health subgroups and differences were also analyzed. Mixture modeling was applied to the Korean Longitudinal Survey of Women & Families to achieve the research objectives. The major findings of this study were as follows. First, there were four subgroups that could be defined according to the work-family spillover: mid-level spillover group (mid-positive and mid-negative spillover group), high-level spillover group (high-positive and high-negative spillover group), low-level spillover group (low-positive and low-negative spillover group), and high-negative and low-positive spillover group. Second, the results of mixture regression analysis to test the effect of eco-system variables showed that age, academic background, non-traditional family value, number of children, work hours, wage income, and availability of the maternity leave were significant determinants of the latent groups. The probability of classifying in the high-negative and low-positive spillover group increased when women showed a lower academic background and wage income, higher number of children and older age, and longer work hours than others. Third, the high-level spillover group, and the high-level spillover group showed the lowest stress and the lowest depression; however, the low-level spillover group reported the highest stress and the highest depression. Implications, limitations, and future directions were discussed based on the results.

• The Journal of Korean Academy of Prosthodontics
• /
• v.34 no.3
• /
• pp.533-538
• /
• 1996

A study of shear bond strength between porcelain and alloy pretreated with sandblasting, sputter etching, and sputter etching after sandblasting was established by Instron universal testing machine. 1. Sputter etched group after sandblasted(group IV) and sandblasted group(group II) were stronger than control group(group I) (P<0.05). 2. Sputter etched group(group III) and control group(group I) were not different(P>0.05).

• Proceedings of the Korean Fiber Society Conference
• /
• 2007.11a
• /
• pp.401-402
• /
• 2007

See Full Text

• Culinary science and hospitality research
• /
• v.18 no.3
• /
• pp.252-265
• /
• 2012

This study was intended to develop a value-added and functional sauce with addition of Chungkukjang powder. This study was conducted as the following procedure. 10%, 20%, 30%, and 40% of Chungkukjang powder was respectively added to make different Bechamel sauces. And then, physical testing (moisture, color value, viscosity, salinity, spreadability and pH) and sensory testing (a quantitative descriptive analysis and an acceptance test) were performed. After that, the correlation between the physical testing and the sensory testing was investigated to choose an optimal mixture ratio. The study results are presented as follows. As the addition percentage of Chungkukjang powder increased, a-value, b-value, salinity, spreadability, and pH significantly increased (p<0.001), but moisture content, L-value and viscosity decreased. The QDA result indicated that, regarding color intensity(5.89), Chungkukjang flavor(5.32) and Chungkukjang taste(6.26), the 40% addition group had the highest value, and that, regarding thickness(6.42), milk flavor(5.00), oily taste(5.21), mouth feel(5.32), the control group had the highest value. As a result, as the addition percentage of Chungkukjang powder increased, color intensity, Chungkukjang flavor, and Chungkukjang taste increased, but thickness, milk flavor, oily taste, and mouth feel decreased. According to the result of acceptance test, the 20% addition group had the highest value in terms of appearance, flavor, taste, glossy and overall acceptance. As shown earlier, it is considered that proper addition of Chungkukjang powder positively affects the overall acceptance, and that the 20% addition of Chungkukjang powder is most suitable to improve the sensory and physical quality-characteristics of Bechamel sauce.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.30 no.2
• /
• pp.112-120
• /
• 2014

Purpose: This study compared the shear bond strength of heat pressed and feldspathic porcelain to metal. Through thermocycling, the clinical aspect of heat pressed porcelain fused metal was estimated. Materials and Methods: 90 non-precious metal specimens were made ($4{\times}4{\times}8 mm$) and divided to three groups. All spicimens were treated and built-up with the porcelain ($4{\times}4{\times}3 mm$) by 2 different methods according to group: Group I: $Inspiration^{(R)}$, Group II: Ivoclar, IPS $Inline^{(R)}PoM$, Group III: GC Initial IQ-One $Body^{(R)}PoM$. The half of each group's specimens were thermocycled. All specimens' shear bond strength were measured by Instron universal testing machine. Exact measuring point was far 1 mm from porcelain/metal interface to the porcelain side. For the statistical analysis, 2-way ANOVA was used. Results: In no-thermocycling specimens, the shear bond strength showed no statistical significance between each group (P > 0.05). In comparison between nothermocycling and thermocycling specimens in each group, the shear bond strength was decreased according to thermocycling, but there was no statistical significance (P > 0.05). In thermocycling specimens, there was no statistical significance between each group (P > 0.05). Conclusion: In feldspathic porcelain and other two types heat pressed porcelain, there was no statistical difference in the shear bond strength of porcelain to metal. The heat pressed porcelain seems to be clinically useful for the aspect of the shear bond strength.

• Journal of Pharmacopuncture
• /
• v.17 no.2
• /
• pp.57-66
• /
• 2014

Objectives: This study was performed to analyze single dose toxicity and the lethal dose of Scolopendrid Pharmacopuncture in rats. Methods: All experiments were conducted at the Korea Testing & Research Institute (KTR), an institution authorized to perform non-clinical studies, under the regulations of Good Laboratory Practice (GLP). Sprague-Dawley rats were chosen for the pilot study. Doses of Scolopendrid pharmacopuncture, 0.1, 0.5, and 1.0 mL, were administered to the experimental group, and 1.0 mL doses of normal saline solution were administered to the control group. This study was conducted under the approval of the Institutional Animal Ethic Committee. Results: No deaths or abnormalities occurred in any of the groups. No significant changes in the weight, hematological parameters or clinical chemistry were noted between the control group and the experimental group. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The above findings suggest Scolopendrid Pharmacopuncture is a relatively safe to use for treatment. Further studies on the subject should be conducted to yield more concrete evidence.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.24 no.5
• /
• pp.465-475
• /
• 2004

This paper is the first part of the study on the development of a smart active layer (SAL) sensor, which consists of two parts. In this first part, the theory and concept of the SAL sensor is investigated, which is designed for the detection of elastic waves caused by internal cracks and damages in structures. For the development SAL sensor, (i) the basic theory of elastic waves was studied, (ii) the feasible study of the SAL as an elastic waves detection sensor using the finite element analysis (FEA) with respect to a piezoceramic disc was performed. (iii) the comparison of performances between some piezoceramic sensors and a commercial acoustic emission (AE) sensor was accomplished to ensure the applicability by the experimental means, such as a pencil lead break test. Also, the conceptional study for the SAL sensor, which can be utilized for the effective detection and locating of defects by the arrangement of regularly distributed sensors, was discussed.

• Phonetics and Speech Sciences
• /
• v.3 no.4
• /
• pp.63-70
• /
• 2011

Recent studies on English $L^*$ (low pitch accent) have revealed the difference of changes in acoustic manifestation between utterances produced by Koreans and those produced by native speakers of English. However, not much effort has been made to compare $L^*$ focused constituents and non-focused constituents. At the same time, most previous works on focus realization are lacking in terms of normalization of acoustic measurement. Therefore, this research is dedicated to comparing the $L^*$ focused items and non-focused items realized by Koreans and Americans and to examining the realization of English $L^*$ produced by the two language groups with improved normalization of the acoustic features (F0, intensity and duration). Within-group analysis comparing focused words and non-focused words showed both Americans and Koreans prolonged the $L^*$ focused syllables but the effect size of syllable lengthening made by Koreans was far less than that made by Americans. Furthermore, significant F0 lowering was found in Americans but not in Koreans. However, the effect of intensity change caused by $L^*$ focus was not significant within each group. The effect of focused words was tested between the two groups revealing that Koreans implemented English $L^*$ focus with higher F0, lower intensity and shorter duration than Americans. In the instances in which a significant Group x Focus Location (initial, middle and final of a sentence) interaction was found, further analysis testing the effect of Group on each Focus Location was conducted. The testing showed that the Koreans produced shorter syllables at initial and middle of a sentence and higher F0 at initial of a sentence than Americans. Implications for the intonation training were also discussed.