• 제목/요약/키워드: Group movement

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총명탕(聰明湯)과 목근피총명탕(木槿皮聰明湯)이 CT105와 ${\beta}A$로 유도된 Alzheimer's Disease 병태(病態) 모델에 미치는 영향 (The Effects of ChongMyungTang(CMT) and ChongMyungTang added Hibiscus syriacus(MCMT) Extract on the Alzheimer's Disease Model Induced by CT-105 and ${\beta}A$)

  • 박지운;정인철;이상룡
    • 동의신경정신과학회지
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    • 제17권1호
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    • pp.37-57
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    • 2006
  • Objective : This research investigates the effect of the CMT and MCMT on Alzheimer‘s disease. Methods : The effects of the CMT and MCMT extract on (1) amyloid precursor proteins(APP), acetylcholinesterase(AChE) mRNA of PC-12 cells treated with CT-105; (2) the AChE activity and the APP production of PC-12 cell treated with CT-105; (3) the behavior; (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA, GFAP, CD68 abd CD11b; (5) the infarction area of the hippocampus in Alzheimer's diseased mice induced with ${\beta}A$ were investigated. Results : 1. The CMT and MCMT extract suppressed the expression of APP, AChE, and mRNA in PC-12 cells treated with CT-105. 2. The CMT and MCMT extract suppressed the AChE activity, and the production of APP significantly in PC-12 cells treated with CT-105. 3. For the CMT and MCMT extract group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency. 4. The CMT and MCMT extract suppressed the over-expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA, GFAP, CD68 abd CD11bCD68/GFAP, in the mice with Alzheimer's disease induced by ${\beta}A$. 5. The CMT and MCMT extract reduced the infarction area of hippocampus with Alzheimer's disease induced by ${\beta}A$ 6. The MCMT showed more excellent effects than CMT in the every experiments except PC-12 cells. Conclusions : These results suggest that the CMT and MCMT extract may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the CMT and MCMT extract for Alzheimer's disease is suggested for future research.

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목근피(木槿皮)가 CT105와 ${\beta}A$로 유도된 Alzheimer's Disease 병태(病態) 모델에 미치는 영향 (The Effects of Hibiscus syriacus(HSS) Extract on the Alzheimer's Disease Model Induced by CT-105 and ${\beta}A$)

  • 최병만;정인철;이상룡
    • 동의신경정신과학회지
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    • 제15권2호
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    • pp.119-139
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    • 2004
  • This research investigates the effect of the Hibiscus syriacus(HSS) on Alzheimer's disease. Specifically, the effects of the HSS extract on (1) $IL-1{\beta}$, IL-6, and $TNF-{\alpha}$ mRNA of PC-12 cells treated with LPS; (2) amyloid precursor proteins(APP), acetylcholinesterase(AChE), and glial fibrillary acidic protein(GFAP) mRNA of PC-12 cells treated with CT-105; (3) the AChE activity and the APP production of PC-12 cell treated with CT-105; (4) the behavior; (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, $IL-1{\beta}$ mRNA, $TNF-{\alpha}$ mRNA, and reactive oxygen species(ROS); (5) the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with ${\beta}A$ were investigated. The results were summarized below ; 1. The HSS extract suppressed the expression of $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ mRNA in THP-l cells treated with LPS. 2. The HSS extract suppressed the expression of APP, AChE, and GFAP mRNA in PC-12 cells treated with CT-105. 3. The HSS extract suppressed the AChE activity, and the production of APP significantly in PC-12 cells treated with CT-105. 4. For the HSS extract group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency. 5. The HSS extract suppressed the over-expression of $IL-1{\beta}$, $TNF-{\alpha}$, $IL-1{\beta}$ and $TNF-{\alpha}$ mRNA, CD68/GFAP, ROS in the mice with Alzheimer's disease induced by ${\beta}A$. 6. The HSS extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by ${\beta}A$. These results suggest that the HSS extract may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the HSS extract for Alzheimer's disease is suggested for future research.

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차원 인체 스캔 데이터를 활용한 한국 중년여성 토르소 원형 설계 (Torso Pattern Design for Korean Middle-Aged Women using 3D Human Body Scan Data)

  • 김혜진;박순지
    • 한국의류산업학회지
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    • 제13권4호
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    • pp.600-613
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    • 2011
  • The purpose of this study is to provide Torso pattern for Korean middle-aged women using 3D human body scan data. 155 women in their 40's or 50's were measured by Martin's anthropometry. Merging the data of 914 middle aged women provided by Korean agency for technology and standards, total of 1,069 subjects' data were analyzed. For data analysis, ANOVA, factor analysis and cluster analysis were done using SPSS PC+. And representative subject of each cluster was selected and they participated in 3D scanning and Torso pattern suggested for middle-aged women Torso pattern which investing the amount of ease according to each group for diffuse front interscye 30%, armscye circumference 30%, back interscye 40% using 3D human body scan data. The results of this study are as follows. Firstly, as a result of the factor analysis, the first factor was 'obesity index of body', The second factor was 'verticality size of body', The third factor was 'verticality length of upper bodice', The fourth factor was 'drop value to represent silhouette', and the fifth factor was 'physique of upper bodice'. And, middle-aged women type were classified 3 types according to the cluster analysis. Type 1(Y-type) was the long upper Torso with wide shoulder. Type 2(H-type) was flat-body type with comparatively thin upper bodice and thin lower bodice. And type 3(A-type) was the obese type with comparatively thin upper bodice and fat lower bodice. Secondly, using CAD program, point filtering was performed and approximated surface model was made. It used that generated surface smoothing corrected for abnormally extruded points and scattered points based on the curvature information. And 3D surfaces were flatted onto the plane by the internal tools of CAD program. Difference ratios of outline length and area between 3D curves and 2D plane were 0.42% and 0.54%, respectively. Third, wearing test by the sensory evaluation showed that distinct difference almost every category. The movement functionality test shows that, in all the tests which reveal significant differences, especially, 'comparison pattern A' experienced inconvenience to neck width and neck depth.

대학 교양무용 수업의 반성적 실천 사례 (The Case Study of Reflective Practice of the Liberal Dance Class in University)

  • 박지원;김제영;김지영
    • 한국콘텐츠학회논문지
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    • 제13권11호
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    • pp.626-635
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    • 2013
  • 이 연구의 목적은 대학의 교양교육으로 이루어지는 무용 수업에서 교육내용 설계와 개선을 위한 실천적인 사례 연구이다. 이 연구는 15주간의 무용 강좌에서 40명이 참여한 생활무용 프로그램에 관하여 다루고 있다. 학생들의 인터뷰 내용과 보고서, 수업을 진행한 강사의 평가서를 토대로 수업사례에서의 실천적 의미를 탐구하고 과정을 중시하는 질적 연구로 이루어졌다. 그 결과, 다음과 같은 세 가지 측면의 경험적 의미를 발견할 수 있었다. 첫째, '생각하는 춤'의 경험이다. 기능적인 움직임에 그치지 않고, 춤의 매력과 감성과 문화를 모두 경험할 수 있었다는 점에서이다. 둘째, '소통하는 춤'의 경험이다. 새로운 동료와의 교제, 소극적인 성향의 극복, 상대를 배려하는 춤의 매너에서 춤을 통한 사회성을 경험할 수 있었다는 것이다. 셋째, '함께 만드는 춤'의 경험이다. 모둠활동의 구성원으로써 성실함과 책임감 있는 태도, 협동적인 과제 수행에서의 보람을 언급했다. 교사의 관점에서 바라보는 수업의 반성적 평가는 다음과 같다. 교양교육으로써 무용교육은 학생들의 표현적 개성과 잠재력을 개발하는 것이 중요하다는 것이다. 기초안무를 그대로 답습하고 기능만을 강요하는 것은 오히려 학생을 지치게 할 수 있다는 점이다. 따라서 교양교육으로써 무용교육은 움직임 활동을 통해 자신을 새롭게 발견하고, 창의적인 생각을 이어나갈 수 있도록 유도하는 것에 초점을 두어야 한다.

제4기 토함분지 (Quaternary Toham Basin)

  • 최성자;홍덕균;최위찬;김명진;이석규
    • 자원환경지질
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    • 제37권5호
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    • pp.533-541
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    • 2004
  • 활성단층 연구가 시작된 이래로 제4기 퇴적층에 대한 관심이 높아지게 되었으며 단구 지형에 퇴적된 미고결 퇴적물에 대하여 많은 자료가 축척되어 있으나, 지금까지 고결된 제4기 지층에 대한 자료는 보고 된 바 없다. 토함산 동쪽의 탐정리와 장항리에는 단단하게 고화되어 있는 역층이 두껍게 발달하고 있다. 이 층을 조양도폭(Tateiwa, 1924)에서는 연일층군의 기저역암인 천북역암으로 보았으며, 손문 등(2000)는 제3기 퇴적분지인 와읍분지 남서부 지괴를 구성하고 있는 송전층에 대비한 바 있으나, 이 퇴적층의 분포를 추적하여 보면 제4기의 미고결 역질층과 정면으로 대치되고 있다. 이 역질층에 협재되어 있는 적갈색 내지 청회색의 사질층에 대한 OSL 연대 측정결과 85∼92ka의 연대가 산출되었으므로 신제3기 전기 마이오세의 천북역암이 아닌 제4기 최후기 간빙기(MIS 5c∼5e)로 확인되었다. 이 역질층을 토함산층으로 명명하였으며 거각력질 층준과 역질 층준으로 분류된다. 이 층은 연일구조선의 분절단층인 외동단층과 연일단층에 의하여 규제되는 북북동방향의 장방형 퇴적분지 내에서 발달하고 있으며, 이 분지를 토함분지라 정하였다. 플라이오세부터 가해진 동서압축력에 의한 서향 역단층 운동은 최후기 간빙기 동안인 약 10만 년 전 까지 계속되었으며, 서향압축에 수반된 정단층이 동쪽으로 일어나 붕적층이 퇴적되어 토함분지가 형성되었다.

녹용대보탕이 ${\beta}-Amyloid$로 유도(誘導)된 Alzheimer's Disease 병태(病態) 모델에 미치는 영향(影響) (The Effects of NogYongDaeBoTang,(NYDBT)on the Alzheimer's Disease Model Induced by CT-105 and $A{\beta}$)

  • 서규태;이은경;최철홍;정대규
    • 동의신경정신과학회지
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    • 제18권2호
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    • pp.101-132
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    • 2007
  • Objective : This research investigates the effect of the NogYongDaeBoTang,(NYDBT) on Alzheimer's disease. Method : The effects of the NYDBT extract on (1) $IL-1{\beta}$, IL-6, and $TNF-{\alpha}$ mRNA of PC-12 cells treated with LPS; (2) acetylcholinesterase(AChE), amyloid precursor proteins(APP), and glial fibrillary acidic protein(GFAP) mRNA the AChE activity and the APP production of PC-12 cell treated with CT-105; (3) the behavior; (4) expression of $IL-1{\beta}$, $TNF-{\alpha}$, MDA, $IL-1{\beta}$ mRNA, and $TNF-{\alpha}$ mRNA; (5) the infarction area of the hippocampus, and brain tissue injury in Alzheimer‘s diseased mice induced with ${\beta}A$ were investigated. Results : 1. The NYDBT extract suppressed the expression of $IL-1{\beta}$, IL-6 and $TNF-{\alpha}$ mRNA in BV2 microglia cell line treated with LPS. 2. The NYDBT extract suppressed the expression of $IL-1{\beta}$, IL-6, and $TNF-{\alpha}$ protein production in BV2 microglia cell line treated with LPS. 3. For the NYDBT extract group a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by $A{\beta}$ in the Morris water maze experiment, which measured stop-through latency, and distance movement-through latency. 4. The NYDBT extract suppressed the over-expression of $IL-1{\beta}$ protein, $TNF-{\alpha}$ protein, MDA, and CD68/CD11b, in the mice with Alzheimer's disease induced by $A{\beta}$. 5. The NYDBT extract reduced the infarction area of hippocampus, and controlled the injury of brain tissue in the mice with Alzheimer's disease induced by $A{\beta}$. 6. The NYDBT extract reduced the Tau protein, GFAP protein, and presenilin1/2 protein (immunohistochemistry) of hippocampus in the mice with Alzheimer's disease induced by $A{\beta}$. Conclusions : These results suggest that the NYDBT extract may be effective for the prevention and treatment of Alzheimer's disease.

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손과 손가락 근관절운동이 노년기 여성의 악력과 잡기력에 미치는 영향 (The Effect of Hand and Finger Exercise on Grip Strength and Pinch Pressure in Elderly Women)

  • 김종임;김현리;김선애
    • 근관절건강학회지
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    • 제9권1호
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    • pp.18-27
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    • 2002
  • Introduction : Exercise has been suggested as an important nursing strategy in which to help elderly maintain functional performance and to enhanced quality of life. Most of exercise study has been reported on fitness exercise such as walking, swimming, dance etc for health of elderly. There have been few reports about exercise on the promotion of small and fine movement of elderly. The purpose of this pilot study was to determine an effect of 6 weeks hand and finger exercise in home to improve hand muscle strength such as grip strength and finger pinch pressure. Materials and Methods Design: This pilot study was used one group pre and post-test design. Sample: Twelve elderly women above 60 years of age or older living in community were selected by convenient sampling. Procedure: Signed informed consent was obtained prior to participate in this study. The authors met elderly and taught hand and finger exercise, daily a week for 6 weeks, within 30 minutes per session. But exercise frequency and strength were not same. Instruments: Left and right grip strength were measured by Bulb Dynamometer(made in USA) and left and right pinch pressure were measured by Baseline Hydraulic Pinch Gauge(made in USA). Data analysis: Discriptive data analyses were performed on all variables. Wilcoxon matched-pairs Signed-Ranks test were used to find difference of grip strength and pinch pressure between pre and post exercise using SPSS 10.0 for Window. Results: Samples age ranged from 60 to 73, Mean age was 65.3. All were women. Ten elderly were diagnosed osteoarthritis and one had DM. After six weeks hand and finger exercise, Left and right grip strength were higher than those of before exercise(Z=-2.667, P<0.01 ; Z=-3.065, p<0.01). And left pinch pressure after hand and linger exercise were higher than that of before pinch pressure (Z=-2.315, p<0.05). But Right pinch pressure was not shown significant change(Z=-1.099, p>0.05). Conclusions: Although this study was limited by the sample size and design, the findings provide some important implications for community based exercise nursing intervention. Short term (six weeks) exercise of hand and linger is shown to be useful as nursing intervention to maintain routine daily activities such as eating, writing, grip something for elderly.

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자연기흉에 대한 Thoracoscopy 의 임상적의의 (Clinical Significance of Thoracoscopy on Spontaneous Pneumothorax)

  • 김영태;김근호
    • Journal of Chest Surgery
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    • 제8권1호
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    • pp.19-28
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    • 1975
  • The thoracoscopic study was reported on 21 cases of spontaneous pneumothorax requiring surgical management, and clinical values of thoracoscopic examination on spontaneous pneumothorax were also discussed. patients were treated in the Department of .Thoracic Surgery, Hanyang University Hospital for the period of two Years from May 1972 to April 1974. For exact detection of etiologic factors on spontaneous pneumothorax, the thoracoscopic examination in the intrapleural space was performed in parallel with X-ray study. this study, the difference of diagnostic and therapeutic significance between radiological and thoracoscopic findings were observed and compared simultaneously. The results are summerized as follows: Patients age was distributed between 3 and 70 years old with highest incidence in the age group of sixty decade [33. 3%], and sex ratio of male to female was 5:2. The tuberculous processes which developed superficial subpleural layer in the lung parenchyme, on the pulmonary surface could be observed by thoracoscopic examination in a characteristic picture. detection ratio of pulmonary tuberculosis by the radiologic study to that by thoracoscopy was 8:2. The adhesion between the visceral and the parietal pleura which could possibly make a rupture of the alveola and the visceral pleura was found to be localized in a small area of the lung surface. The other part of the lung surface was free of the adhesion and, therefore, the movement of the lung took place completely without any difficulty. The ruptured orifice of the pleura and pathological changes surrounding the orifice can be detected by thoracoscopy, but not by other means such as radiologic examination. A single tuberculous bleb and multiple emphysematous blebs were found on 6 cases out of 21 cases of spontaneous pneumothorax. Among these cases, radiologic Study revealed the bleb only in one patient. On the other hand, the blebs were found in all the six patients by means of thoracoscopic examination. It gives the detection ratio of bleb by radiologic study to that by thoracoscopy was 1:6. By thoracoscopy, the rupture on the lung surface were visualized on the 10 patients out of a total of 21 patients [10 patients of visual rupture]. However, the rupture of the pleura was not observed on the rest of 11 patients even by thoracoscopic examination [11 patients of non visual rupture]. Five patients [50%] out of ten who had the visual rupture on the lung surface was required a surgical operation to remove pneumothorax. For the patients who were detected to have the visual rupture of the pleura by thoracoscopy, be considered in the early stage of closed thoracostomy. of 21 patients, 16 patients [11 patients of non visual rupture of the pleura and 5 patients of visual rupture of the pleura] who received no surgical management, were treated with closed thoracostomy with continuous suction, and the` pneumothorax was healed completely up in each cases. Therapeutic measures for the remaining 5 patients of visual rupture of the pleura who were subjected to surgical approach for radical treatment of spontaneous pneumothorax were accordingly complicated, and the following different procedures were properly indicated case by case, that is, rib resection thoracostomy, simple closure of ruptured visceral pleura, wedged resection of the lung, and lobectomy.

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Arshile Gorky와 Jackson Pollock의 Painting이 현대의상 직물 문양에 미친 영향 (The Influence of Arshile Gorky's & Jackson Pollock's Painting on Modern Fashion)

  • 정흥숙
    • 한국의류학회지
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    • 제16권3호
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    • pp.197-207
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    • 1992
  • Expressionism, is as diverse as the artists invo)ved, in a very broad sense two main tendencies may be noted. The first is that of the Action painters, concerned in different ways with the gesture of the brush and the texture of the paint. It included such major artists as Arshile Gorky, Jackson Pollock, Willem De Keening, and Franz Kline. The other group consisted of the Color Field painters, concerned with the statement of an abstract sign or tranquil image in terms of a large, unified color shape or area. Here must be included Mark Rothko, Barnett Newman, Ad Rdinhardt, as well as, to a degree, Adolph Gottlieb, Robert Motherwell, and Clyf(ord Still. In this paper, 1 selected two artists Arshile Gorky and Jackson Pollock independent charac-teristics and studied the influence of their Action painting on the fabrics of modern fashion. However, it should be noted it was never the intention of the critic Harold Rosenberg, in coining this term, to imply that Action painting was a kind of athletic exercise. Nor is it true that the furious and seemingly haphazard scattering of the paint involved a completely uncontrolled, intuitive act. There is no question that, in the paintings of Jackson Pollock, Arshile Gorky and many of the other Abstract Expressionists, the element of intuition or the accidental plays a large and deliberate part; this was indeed one of the principal contributions of Abstract Expressionism which had found its own inspiration in surrealism's 'psychic automaton'. However, nothing that an experienced and accomplished artist does can be completely accidental. Aside from their intrinsic quality, the spun-out skeins of poured pigments contributed other elements that changed the course of modern painting. There was the concept of the all-over painting, the painting seemingly without beginning or end, extending to the very limits of the canvas and implying an extension even beyond. The feeling of absorption or participation is heightened by the ambiguity of the picture space. The colors and lines, although never punctur-ing deep perspective holes in the surface, still create an illusion of continuous movement, a billowing, a surging back and forth, within a limited depth. To study the influence of Abstract Expressionism on the fabric of modern fashion, 1 selected and examined four fashion magazines: Collezioni published in France, Bazaar in Italy, Gap in Japan and Vogue in the U.S.a. froim January 1989 to June 1991. As a result of this review I found that some fabrics used in modern clothing are printed in a dripping, pouring and splashing style without any meaning or form. Slides included in the presentation show that modern fabrics which are printed in such a style were influenced by Abstract Expressionism. The slides also show that these abstract prints are well suited to modern fashion design.

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학령기 아동의 감각처리능력과 놀이 선호도의 상관관계 (The Correlation of Sensory Processing Abilities and Play Preferences of School-Age Children)

  • 김예지;김지원;윤나래;장문영
    • 대한감각통합치료학회지
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    • 제12권1호
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    • pp.1-11
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    • 2014
  • 목적 : 본 연구의 목적은 학령기 아동의 감각처리능력과 놀이선호도 간의 관련성을 파악하고 놀이선호도에 영향을 주는 감각처리요인을 알아보고자 한다. 연구 방법 : 2012년 10월 22일부터 24일까지 경남 김해시에 소재한 초등학교의 S초등학교의 4학년 아동 48명을 대상으로 Short Sensory Profile (SSP)과 Pediatric Interest Profile (PIP)을 사용하여 감각처리능력과 놀이선호도를 평가 분석하였다. 결과 : 전체 대상자의 감각처리능력과 8가지 놀이 항목의 빈도, 선호도, 숙련도에서. Outdoor activities 선호도는 맛/냄새 민감성, 청각여과, 총점과 상관관계가 유의한 것으로 나타났고, Creative activities 선호도와 숙련도는 맛/냄새 민감성과의 상관관계가 유의한 것으로 나타났다. Lessons / Classes 선호도는 촉각 민감성, 맛/냄새민감성, 움직임 민감성, 청각여과, 시각/청각 민감성, 총점과 유의한 상관관계를 가지고, Lessons / Classes 빈도와 숙련도는 시각/청각 민감성과 유의한 상관관계를 가진다. 결론 : 본 연구에서 감각처리기능과 놀이선호도의 상관관계가 통계적으로 유의하게 나타나지는 않았으나 일부 놀이 항목과는 유의한 상관관계를 가지고 있는 것으로 나타났다. 연구에 제시된 학령기 아동의 감각처리능력과 상관관계가 있는 놀이 항목을 확인하여 아동의 놀이 선호도와 놀이 작업치료 시 제공하는 놀이 활동의 수준을 결정할 수 있는 기초자료를 제공에 의의가 있다.