• 제목/요약/키워드: Group Signature

검색결과 138건 처리시간 0.03초

Genetic diversity and divergence among Korean cattle breeds assessed using a BovineHD single-nucleotide polymorphism chip

  • Kim, Seungchang;Cheong, Hyun Sub;Shin, Hyoung Doo;Lee, Sung-Soo;Roh, Hee-Jong;Jeon, Da-Yeon;Cho, Chang-Yeon
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권11호
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    • pp.1691-1699
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    • 2018
  • Objective: In Korea, there are three main cattle breeds, which are distinguished by coat color: Brown Hanwoo (BH), Brindle Hanwoo (BRH), and Jeju Black (JB). In this study, we sought to compare the genetic diversity and divergence among there Korean cattle breeds using a BovineHD chip genotyping array. Methods: Sample data were collected from 168 cattle in three populations of BH (48 cattle), BRH (96 cattle), and JB (24 cattle). The single-nucleotide polymorphism (SNP) genotyping was performed using the Illumina BovineHD SNP 777K Bead chip. Results: Heterozygosity, used as a measure of within-breed genetic diversity, was higher in BH (0.293) and BRH (0.296) than in JB (0.266). Linkage disequilibrium decay was more rapid in BH and BRH than in JB, reaching an average $r^2$ value of 0.2 before 26 kb in BH and BRH, whereas the corresponding value was reached before 32 kb in JB. Intra-population, interpopulation, and Fst analyses were used to identify candidate signatures of positive selection in the genome of a domestic Korean cattle population and 48, 11, and 11 loci were detected in the genomic region of the BRH breed, respectively. A Neighbor-Joining phylogenetic tree showed two main groups: a group comprising BH and BRH on one side and a group containing JB on the other. The runs of homozygosity analysis between Korean breeds indicated that the BRH and JB breeds have high inbreeding within breeds compared with BH. An analysis of differentiation based on a high-density SNP chip showed differences between Korean cattle breeds and the closeness of breeds corresponding to the geographic regions where they are evolving. Conclusion: Our results indicate that although the Korean cattle breeds have common features, they also show reliable breed diversity.

Wearable Computers

  • Cho, Gil-Soo;Barfield, Woodrow;Baird, Kevin
    • 섬유기술과 산업
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    • 제2권4호
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    • pp.490-508
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    • 1998
  • One of the latest fields of research in the area of output devices is tactual display devices [13,31]. These tactual or haptic devices allow the user to receive haptic feedback output from a variety of sources. This allows the user to actually feel virtual objects and manipulate them by touch. This is an emerging technology and will be instrumental in enhancing the realism of wearable augmented environments for certain applications. Tactual displays have previously been used for scientific visualization in virtual environments by chemists and engineers to improve perception and understanding of force fields and of world models populated with the impenetrable. In addition to tactual displays, the use of wearable audio displays that allow sound to be spatialized are being developed. With wearable computers, designers will soon be able to pair spatialized sound to virtual representations of objects when appropriate to make the wearable computer experience even more realistic to the user. Furthermore, as the number and complexity of wearable computing applications continues to grow, there will be increasing needs for systems that are faster, lighter, and have higher resolution displays. Better networking technology will also need to be developed to allow all users of wearable computers to have high bandwidth connections for real time information gathering and collaboration. In addition to the technology advances that make users need to wear computers in everyday life, there is also the desire to have users want to wear their computers. In order to do this, wearable computing needs to be unobtrusive and socially acceptable. By making wearables smaller and lighter, or actually embedding them in clothing, users can conceal them easily and wear them comfortably. The military is currently working on the development of the Personal Information Carrier (PIC) or digital dog tag. The PIC is a small electronic storage device containing medical information about the wearer. While old military dog tags contained only 5 lines of information, the digital tags may contain volumes of multi-media information including medical history, X-rays, and cardiograms. Using hand held devices in the field, medics would be able to call this information up in real time for better treatment. A fully functional transmittable device is still years off, but this technology once developed in the military, could be adapted tp civilian users and provide ant information, medical or otherwise, in a portable, not obstructive, and fashionable way. Another future device that could increase safety and well being of its users is the nose on-a-chip developed by the Oak Ridge National Lab in Tennessee. This tiny digital silicon chip about the size of a dime, is capable of 'smelling' natural gas leaks in stoves, heaters, and other appliances. It can also detect dangerous levels of carbon monoxide. This device can also be configured to notify the fire department when a leak is detected. This nose chip should be commercially available within 2 years, and is inexpensive, requires low power, and is very sensitive. Along with gas detection capabilities, this device may someday also be configured to detect smoke and other harmful gases. By embedding this chip into workers uniforms, name tags, etc., this could be a lifesaving computational accessory. In addition to the future safety technology soon to be available as accessories are devices that are for entertainment and security. The LCI computer group is developing a Smartpen, that electronically verifies a user's signature. With the increase in credit card use and the rise in forgeries, is the need for commercial industries to constantly verify signatures. This Smartpen writes like a normal pen but uses sensors to detect the motion of the pen as the user signs their name to authenticate the signature. This computational accessory should be available in 1999, and would bring increased peace of mind to consumers and vendors alike. In the entertainment domain, Panasonic is creating the first portable hand-held DVD player. This device weight less than 3 pounds and has a screen about 6' across. The color LCD has the same 16:9 aspect ratio of a cinema screen and supports a high resolution of 280,000 pixels and stereo sound. The player can play standard DVD movies and has a hour battery life for mobile use. To summarize, in this paper we presented concepts related to the design and use of wearable computers with extensions to smart spaces. For some time, researchers in telerobotics have used computer graphics to enhance remote scenes. Recent advances in augmented reality displays make it possible to enhance the user's local environment with 'information'. As shown in this paper, there are many application areas for this technology such as medicine, manufacturing, training, and recreation. Wearable computers allow a much closer association of information with the user. By embedding sensors in the wearable to allow it to see what the user sees, hear what the user hears, sense the user's physical state, and analyze what the user is typing, an intelligent agent may be able to analyze what the user is doing and try to predict the resources he will need next or in the near future. Using this information, the agent may download files, reserve communications bandwidth, post reminders, or automatically send updates to colleagues to help facilitate the user's daily interactions. This intelligent wearable computer would be able to act as a personal assistant, who is always around, knows the user's personal preferences and tastes, and tries to streamline interactions with the rest of the world.

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Slot Hybridization을 이용한 연속 회분식 반응기내 미생물 분포 조사 (Microbial Communities of Activated Sludge in an Anaerobic/Aerobic Sequencing Batch Reactor using Slot Hybridization)

  • 전체옥;신금주;이대성;서판길;박종문
    • 대한환경공학회지
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    • 제22권5호
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    • pp.939-947
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    • 2000
  • 연속 회분식 반응기를 이용하여 생물학적 인 제거에 관한 미생물 분포 연구를 수행하였다. 탄소원으로 초산을 넣은 합성 폐수를 사용하였고 미생물 체류 시간과 수리학적 체류 시간은 각각 10일과 16시간으로 유지하였다. 인 방출과 흡수가 운전 시간이 경과됨에 따라 점점 빠르게 일어났으며 약 200일 경과 후 안정적인 인 제거가 유지되었다. 안정적인 생물학적 인 제거가 유지될 때의 미생물 분포를 조사하기 위하여 17개의 ribosomal RNA (rRNA) signature probe를 합성하여 슬러지로부터 분리한 전체 rRNA에 대하여 slot hybridization을 실시하였다. 분리한 전체 RNA에는 proteobacteria의 베타군 (beta subclass)에 속하는 rRNA가 가장 많이 함유되어 있음을 확인하였고 CTE probe와 관계된 rRNA가 다음으로 많이 분포하였다. 전통적으로 생물학적 인 제거를 담당하는 미생물로 여겨져 왔던 Acinetobacter, Aeromonas, Pseudomonas의 rRNA는 10% 미만으로 존재하고 있음이 확인되었다. 이러한 결과로부터 Rhodocyclus 그룹같은 proteobacteria의 베타군과 CTE에 속하는 미생물이 인 제거에 중요한 역할을 수행할 것으로 생각되었고 Acinetobacter, Aeromonas, Pseudomonas 등은 생물학적 인 제거에 있어서 과평가된 것으로 판단되었다.

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동북아시아 지역에서의 공기괴별 HFC-23/HCFC-22의 배출특성 (Emission Characteristics of HFC-23 (CHF3)/HCFC-22 (CHClF2) between Different Air Masses in Northeastern Asia)

  • 리선란;김주일;김경렬
    • 한국대기환경학회지
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    • 제26권5호
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    • pp.490-498
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    • 2010
  • HCFC-22 (chlorodifluoromethane, $CHClF_2$), one of the major components in various refrigeration, is emitted mostly from developing countries, as its consumption is not limited until 2013 by the Montreal Protocol. In addition, HFC-23 (trifluoromethane, $CHF_3$), a by-product in the manufacture of HCFC-22, is also a powerful greenhouse gas. Here, we discuss the regional emission characteristics of these compounds based on high-frequency in-situ measurements using the "Medusa" GC-MS system. HCFC-22 and HFC-23 baseline concentrations measured at Gosan (Jeju Island, Korea) from November 2007 to December 2008 increased by 1.8 ppt/yr and 0.6 ppt/yr, respectively. Pollution events of these compounds were observed, very frequently (e.g., ~2~3 times) at Gosan than baseline levels. All the measurement data were divided into four groups by simultaneously considering the ratio (HFC-23/HCFC-22) and concentration (HCFC-22) at Trinidad Head (TH, California, USA). The residence time of trajectories were then analyzed in each of the four groups. The results exhibited the existence of a strong correlation with air mass origin for each group: 1) Air masses originating from Siberia in the north and from the Pacific in the south had ratios of 0.08~0.12 and concentrations of 196.9~254.3 ppt which is highly comparable to background air at TH. 2) Air masses passing over the Southern China exhibited similar ratios but higher HCFC-22 concentrations. 3) Air masses passing over the Northern China had ratios of 0.12~0.21. 4) Air masses passing over Korea and/or Japan had ratios of 0.01~0.08. Our results suggest that the HFC-23/HCFC-22 ratio can be used as a good indicator for the assessment of the pollution with Chinese origin. We also confirmed differences in air masses traveling over Northern and Southern China, most likely due to differences in air mass travelling speed over these regions before arriving at Gosan. This signature may be treated as one of the critical components in identifying the emission sources from different parts of China.

글로벌 전자무역의 실현을 위한 eUCP의 역할과 개정방안 (A Study on the Roles and Revision of eUCP for Global Electronic Trading)

  • 최석범;홍성규
    • 무역상무연구
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    • 제18권
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    • pp.105-134
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    • 2002
  • In the Spring of 2000, the Banking Commission of the ICC decided to appoint a working group to draft a supplement to the UCP 500 to clarify the position regarding electronic presentation under a documentary credit. Provisions was drafted to supplement its existing rules for documentary credit, that is, UCP 500. These new provisions known as Supplement to UCP 500 for Electronic Presentation was approved by the ICC Banking Commission at the beginning of November 2001 and came in force as of 1 April 2002 The eUCP covers matters such as definitions of key terms such as electronic record, electronic signature, format, paper document, received. An eUCP Credit must specify the formats in which electronic records are to be presented and if not, electronic records may be presented in any format. Electronic records may be presented separately and need not be presented at the same time. The purpose of this paper is to understand the main substance of eUCP and to facilitate the introduction of electronic letter of credit by studying the problems and revision of eUCP and new electronic UCP. The main substances of eUCP are electronic address as place for presentation of electronic records, flexibility of the formats of electronic records to be presented, endowment of the notice of completeness of presentation to the beneficiary, one electronic record satisfying one or more originals or copies of an electronic record, the electronic records to be examined including the electronic record at the hyperlink to an external system or the referenced system, no remark as to the time period for the examination of documents. The Roles of eUCP are the Promotion of the Electronic Trade, the Supply of Basis on the Uniform Rules for Electronic Letter of Credit, the introduction of Electronic Trade Model. The characteristics of eUCP are a supplement to the UCP, no address of any issues relating to the issuance or advice of Credit electronically, independence of specific technologies and developing electronic commerce system, that is, Bolero Service. The Problems of eUCP are flexibility of format of electronic record, heavy burden on the side of banks, and the problems regrading the number of presentation, the notice of completeness of presentation, no provision in regard to the time to examine the electronic records, and representation of the electronic records. In the revision of eUCP to resolve the problems, the things to be taken into consideration are as follows; the designation of the format allowing the banks to examine electronically, prohibition of the paper documents, the development of the system receiving the electronic records, the addition of the reception notice on the side of the banks, the setting of the time to examine the electronic records, the construction of the backup system or the dual processing system.

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Mucosal Immunity Related to FOXP3+ Regulatory T Cells, Th17 Cells and Cytokines in Pediatric Inflammatory Bowel Disease

  • Cho, Jinhee;Kim, Sorina;Yang, Da Hee;Lee, Juyeon;Park, Kyeong Won;Go, Junyong;Hyun, Chang-Lim;Jee, Youngheun;Kang, Ki Soo
    • Journal of Korean Medical Science
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    • 제33권52호
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    • pp.336.1-336.12
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    • 2018
  • Background: We aimed to investigate mucosal immunity related to forkhead box P3 ($FOXP3^+$) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). Methods: Mucosal tissues from terminal ileum and colon and serum samples were collected from twelve children with IBD and seven control children. Immunohistochemical staining was done using anti-human FOXP3 and anti-$ROR{\gamma}t$ antibodies. Serum levels of cytokines were analyzed using a multiplex assay covering interleukin $(IL)-1{\beta}$, IL-4, IL-6, IL-10, IL-17A/F, IL-21, IL-22, IL-23, IL-25, IL-31, IL-33, interferon $(IFN)-{\gamma}$, soluble CD40L, and tumor necrosis factor-${\alpha}$. Results: $FOXP3^+$ Treg cells in the lamina propria (LP) of terminal ileum of patients with Crohn's disease were significantly (P < 0.05) higher than those in the healthy controls. $ROR{\gamma}t^+$ T cells of terminal ileum tended to be higher in Crohn's disease than those in the control. In the multiplex assay, serum concentrations (pg/mL) of IL-4 ($9.6{\pm}1.5$ vs. $12.7{\pm}3.0$), IL-21 ($14.9{\pm}1.5$ vs. $26.4{\pm}9.1$), IL-33 ($14.3{\pm}0.9$ vs. $19.1{\pm}5.3$), and $IFN-{\gamma}$ ($15.2{\pm}5.9$ vs. $50.2{\pm}42.4$) were significantly lower in Crohn's disease than those in the control group. However, serum concentration of IL-6 ($119.1{\pm}79.6$ vs. $52.9{\pm}39.1$) was higher in Crohn's disease than that in the control. Serum concentrations of IL-17A ($64.2{\pm}17.2$ vs. $28.3{\pm}10.0$) and IL-22 ($37.5{\pm}8.8$ vs. $27.2{\pm}3.7$) were significantly higher in ulcerative colitis than those in Crohn's disease. Conclusion: Mucosal immunity analysis showed increased $FOXP3^+$ T reg cells in the LP with Crohn's disease while Th17 cell polarizing and signature cytokines were decreased in the serum samples of Crohn's disease but increased in ulcerative colitis.

중국 현대 클라리넷 작품 중 민족음악 요소 연구 『목마의 노래』와 『파미이지음』을 중심으로 (A Study of Ethnomusicological Elements in Modern Chinese Clarinet focus on 『the Shepherd Horse』 and 『the Voice of the Pamir』)

  • 증광;안성희
    • 한국콘텐츠학회논문지
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    • 제22권6호
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    • pp.261-272
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    • 2022
  • 중국의 오랜 역사 과정에서 풍부하고 소중한 소수민족의 전통음악은 형성되었다. 각 민족은 발전 과정에서 독특한 자연환경과 특수한 생활과 생산 방식에 따라 자기만의 세계관과 음악 문화를 만들어 냈다. 클라리넷은 서양 악기로서, 중국에 전래되는 과정에서 중국 소수민족 문화의 영향을 어느 정도 받아왔다. 따라서 음악가들은 중국 소수민족 음악 중의 여러 요소를 표현하는 데에 서양 악기를 사용하는 방법을 모색했다. 본 논문은 중국 소수민족 음악의 요소를 사용하여 창작된 현대 클라리넷 작품 작곡가 왕염의 『목마의 노래』와 작곡가 호벽정의 『파미이지음』을 중심으로 작품의 형성 유래, 작품에 나타난 예술적인 표현 특징 등 두 측면에서 클라리넷에서 표현되는 민족적인 요소를 분석하고자 한다. 구체적으로는 민족음악의 모드 음계, 박자, 리듬과 선율의 표현기법, 그리고 소수민족 전통 악기를 모방한 소리의 특징 등 다섯 가지 내용으로 구성된다. 또한 지역, 생산, 생활, 민족 정서 등과 접목하여 작품에 사용된 타지크족과 몽골족 음악에 나타난 민족문화의 특징을 분석한다. 본 연구는 중국 현대 클라리넷 작품의 음악 스타일을 습득하고자 하는 창작자와 연주자에게 이론적인 근거를 제공하고 서양 악기로 중국 전통 음악을 연주할 더 좋은 방법을 모색하고자 한다.

Rendezvous Mission to Apophis: III. Polarimetry of S-type: For A Better Understanding of Surficial Evolution

  • 김주연;정민섭;진선호;심채경;박윤수;;권유나;문홍규;최영준;김명진
    • 천문학회보
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    • 제46권2호
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    • pp.57.4-58
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    • 2021
  • Asteroids have undergone various processes such as impacts, space weathering, and thermal evolution. Because they expose their surfaces to space without atmosphere, these evolutional processes have been recorded directly on their surfaces. The remote-sensing observations have been conducted to reveal these evolutional histories of the target asteroids. For example, crater and boulder distributions are unambiguous evidence for past nondestructive impacts with other celestial bodies. Multiband and spectroscopic observations have revealed space-weathering history (as well as compositions). Whereas most physical quantities have been examined intensively using spacecraft and telescopes, only a little has been studied on "the grain size". It is one of the fundamental physical quantities for diagnosing the collisional and thermal history of asteroids. Our group has conducted polarimetric research of asteroids (as well as Moon [1]) to determine the particle size and further investigate the evolutional histories of target asteroids [2],[3]. For example, the existence of regolith on an S-type asteroid, Toutatis, was suggested almost twenty years before space exploration [4]. Moreover, we reported that near-Sun asteroids indicate a signature of submillimeter grains, which could be created by a thermal sintering process by solar radiation [5]. However, it is important to note that in-situ polarimetry has not been reported on the asteroid surface, although the Korean Lunar Exploration Program aims to do polarimetry on the lunar surface [6]. Therefore, it is expected that the polarizer mounted on the Korean Apophis spacecraft can make the first estimate of the grain size and its regional variation over the Apophis surface. In this presentation, we outline research of S-type asteroid surfaces through remote-sensing observations and consider the role of polarimetry. Based on this review, we consider the purpose, potentiality, and strategy of the polarimetry using the onboard device for the Apophis spacecraft. We will report a possible polarization phase curve of Apophis estimated from ordinary chondrites and past observational data of S-type asteroids, taking account of the space weathering effect. Based on this estimation, we will consider the strategy of how to determine the particle size (and space weathering degree) of the Apophis surface. We will also mention the detectability of dust hovering on the surface.

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